Characteristics of small breast and/or ovarian cancer families with germline mutations in BRCA1 and BRCA2

British Journal of Cancer

Volumn 79, Issue 9-10, 1999, Pages 1475-1478

  Ligtenberg, M J L ^a   Hogervorst, F B L ^b   Willems, H W ^a   Arts, P J W ^a   Brink, G ^b   Hageman, S ^b   Bosgoed, E A J ^a   Van Der Looij, E ^a   Rookus, M A ^b   Devilee, P ^c   Vos, E M A W ^b   Wigbout, G ^b   Struycken, P M ^b   Menko, F H ^b,d   Rutgers, E J Th ^b   Hoefsloot, E H ^a   Mariman, E C M ^a   Brunner, H G ^a   Van't Veer, L J ^b  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^b NETHERLANDS CANCER INSTITUTE   (Netherlands)

^c LEIDEN UNIVERSITY   (Netherlands)

^d VU UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Bilateral breast cancer; BRCA1; BRCA2; Breast cancer; Ovarian cancer

Indexed keywords

BRCA1 PROTEIN; BRCA2 PROTEIN;

ARTICLE; BREAST CANCER; CANCER SCREENING; CONTROLLED STUDY; FAMILIAL CANCER; FEMALE; GENE MUTATION; GENETIC PREDISPOSITION; HUMAN; MAJOR CLINICAL STUDY; OPEN READING FRAME; OVARY CANCER; PRIORITY JOURNAL;

EID: 0033009692     PISSN: 00070920     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjc.6690235     Document Type: Article

References (12)

1. Couch FJ, DeShano ML, Blackwood A, Calzone K, Stopfer J, Campeau L, Ganguly A, Rebbeck T and Weber BL (1997) BRCA1 mutations in women attending clinics that evaluate the risk of breast cancer. N Engl J Med 336: 1409-1415
2. Easton DF, Bishop DT, Ford D and Crockford GP (1993) Genetic linkage analysis in familial breast and ovarian cancer: results from 214 families. The Breast Cancer Linkage Consortium, Am J Hum Genet 52: 678-701
3. Hogervorst FBL, Cornelis RS, Bout M, van Vliet M, Oosterwijk JC, Olmer R, Bakker B, Klijn JGM, Vasen HFA, Meijers-Heijboer H, Menko FH, Cornelisse CJ, den Dunnen JT, Devilee P and van Ommen GJB (1995) Rapid detection of BRCA1 mutations by the protein truncation test. Nat Genet 10: 208-212
4. Krainer M, Silva-Arrieta S, FitzGerald MG, Shimada A, Ishioka C, Kanamaru R, MacDonald DJ, Unsal H, Finkelstein DM, Bowcock A, Isselbacher KJ and Haber DA (1997) Differential contributions of BRCA1 and BRCA2 to early-onset breast cancer. N Engl J Med 336: 1416-1421
5. Miki Y, Swensen J, Shattuck-Eidens D, Futreal PA, Harshman K, Tavtigian S, Liu Q, Cochran Ch, Bennett LM, Ding W, Bell R, Rosenthal J, Hussey Ch, Tran Th, McClure M, Frye Ch, Hattier T, Phelps R. Haugen-Strano A, Katcher H, Yakumo K, Gholami Z, Shaffer D, Stone S, Bayer S, Wray Ch, Bogden R, Dayannath P, Ward J, Tonin P, Narod S, Bristow PK, Norris FH, Helvering L, Morrison P, Rosteck P, Lai M, Barrett JC, Lewis C, Neuhausen S, Cannon-Albright L, Goldgar D, Wiseman R, Kamb A and Skolnick MH (1994) A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1. Science 266: 66-71
6. Peelen T, van Vliet M, Petrij-Bosch A, Micremet R, Szabo C, van den Ouweland AWM, Hogervorst F, Brohet R, Ligtenberg MJL, Teugcls E, van der Luijt R, van der Hout AH, Gille JJP, Pals G, Jedema I, Olmer R, van Leeuwen I, Newman B, Plandsoen M, van der Est M, Brink G, Hageman S, Arts PJW, Bakker MM, Willems HW, van der Looij E, Neyns B, Bonduelle M, Jansen R, Oosterwijk JC, Sijmons R, Smeets HJM, van Asperen CJ, Meijers-Heijboer H. Klijn JGM, de Greve J, King MC, Menko FH, Brunner HG, Halley D, van Ommen GJB, Vasen HFA, Cornelisse CJ, van't Veer LJ, de Knijff P, Bakker E and Devilee P (1997) A high proportion of novel mutations in BRCA1 with strong founder effects among Dutch and Belgian hereditary breast and ovarian cancer families. Am J Hum Genet 60: 1041-1049
7. Petrij-Bosch A. Peelen T, van Vliet M, van Eijk R, Olmer R, Drüsedau M, Hogervorst FBL, Hageman S, Arts PJW, Ligtenberg MJL, Meijers-Heijboer H, Klijn JGM, Vasen HFA, Cornelisse CJ, van't Veer LJ, Bakker E, van Ommen GJB and Devilee P (1997) BRCA1 genomic deletions are major founder mutations in Dutch breast cancer patients. Nat Genet 17: 341-345
8. Shattuck-Eidens D, Oliphant A, McClure M, McBride C, Gupte J, Rubano T, Pruss D, Tavtigian SV, Teng DHF, Adey N, Staebell M, Gumpper K, Lundstrom R, Hulick M, Kelly M, Holmen J, Lingenfelter B, Manley S. Fujimura F, Luce M, Ward B, Cannon-Albrigt L, Steele L, Offit K, Gilewski T, Norton L, Brown K, Schulz Ch, Hampel H, Schluger A, Giulotto E, Zuli W, Ravaioli A, Nevanlinna H, Pyrhonen S, Rowley P, Loader S, Osborne MP, Daly M, Tepler I, Weinstein PL, Scalia JL, Michaelson R, Scott RJ, Radice P, Pierotti MA, Garber JE, Isaacs C, Peshkin B, Lippman ME, Dosik MH, Caligo MA, Greenstein RM, Pilarski R, Weber B, Burgemeister R, Frank TS, Skolnick MH and Thomas A (1997) BRCA1 sequence analysis in women at high risk for susceptibility mutations. Risk factor analysis and implications for genetic testing. JAMA 278: 1242-1250
9. Szabo CI and King MC (1997) Population genetics of BRCA1 and BRCA2. Am J Hum Genet 60: 1013-1020
10. Tavtigian SV, Simard J, Rommens J, Couch F, Shattuck-Eidens D, Neuhausen S, Merajver S, Thorlacius S, Offit K, Stoppa-Lyonnet D, Belanger C, Bell R, Berry S, Bogden R, Chen Q, Davis T, Dumont M, Frye C, Hattier T, Jammulapati S, Janecki T, Jiang P, Kehrer R, Leblanc JF, Mitchell JT, McArthur-Morrison J, Nguyen K, Peng Y, Samson C, Schroeder M, Snyder SC, Steele L, Stringfellow M, Stroup C, Swedlund B, Swensen J, Teng D, Thomas A, Tran T, Tran T, Tranchant M, Weaver-Feldhaus J, Wong AKC, Shizuya H, Eyfjord JE, Cannon-Albright L, Labrie F, Skolnick MH, Weber B, Kamb A and Goldgar Dt (1996) The complete BRCA2 gene and mutations in chromosome 13q-linked kindreds. Nat Genet 12: 333-337
11. Wooster R, Neuhausen SL, Mangion J, Quirk Y, Ford D, Collins N, Nguyen K, Seal S, Tran T, Avrill D, Fields P, Marshall G, Narod S, Lenoir GM, Lynch H, Feunteun J, Devilee P, Cornlisse CJ, Menko FH, Daly PA, Onniston W, McManus R, Pye C, Lewis CM, Cannon-Albright LA, Peto J, Ponder BAJ, Skolnick MH, Easton DF, Goldgar DE and Stratton MR (1994) Localization of a breast cancer susceptibility gene, BRCA2, to chromosome 13q 12-13. Science 265: 2088-2090
12. Wooster R, Bignell G, Lancaster J, Swift S, Seal S,Mangion J, Collins N, Gregory S, Gumbs C, Micklem G, Barfoot R, Hamoudi R, Patel S, Rice C, Biggs P, Hashim Y, Smith A, Connor F, Arason A, Gudmundsson J, Ficence D, Kelsell D, Ford D, Tonin P, Bishop DT, Spurr NK, Ponder BAJ, Eeles R, Peto J, Devilee P. Cornelisee C, Lynch H, Narod S, Lenoir G, Egilsson V, Bjork Barkadottir R, Easton DF, Bentley DR, Futreal PA, Ashworth A and Srratton MR (1995) Identification of the breast cancer susceptibility gene. RRCA2. Nature 378: 789-792