BRCA1 genomic deletions are major founder mutations in Dutch breast cancer patients

Nature Genetics

Volumn 17, Issue 3, 1997, Pages 341-345

  Petrij Bosch, Anne ^a   Peelen, Tamara ^a   Van Vliet, Margreethe ^a   Van Eijk, Ronald ^a   Olmer, Renske ^a   Drüsedau, Marion ^a   Hogervorst, Frans B L ^b   Hageman, Sandra ^b   Arts, Petronella J W ^c   Ligtenberg, Marjolijn J L ^c   Meijers Heijboer, Hanne ^d   Klijn, Jan G M ^e   Vasen, Hans F A ^f   Cornelisse, Cees J ^a   Van't Veer, Laura J ^b   Bakker, Egbert ^a   Van Ommen, Gert Jan B ^a   Devilee, Peter ^a  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^b NETHERLANDS CANCER INSTITUTE   (Netherlands)

^c RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^d ERASMUS UNIVERSITY ROTTERDAM   (Netherlands)

^e ERASMUS MEDICAL CENTER   (Netherlands)

^f NLD Found Detection Hered Tumours   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ARTICLE; BREAST CANCER; CONTROLLED STUDY; FEMALE; FOUNDER EFFECT; GENE DELETION; HUMAN; MAJOR CLINICAL STUDY; NETHERLANDS; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TUMOR SUPPRESSOR GENE;

BASE SEQUENCE; BLOTTING, SOUTHERN; BRCA1 PROTEIN; BREAST NEOPLASMS; DEOXYRIBONUCLEASE HINDIII; FEMALE; FOUNDER EFFECT; HAPLOTYPES; HUMANS; MIDDLE AGED; MOLECULAR SEQUENCE DATA; MUTATION; NETHERLANDS; OVARIAN NEOPLASMS; POLYMERASE CHAIN REACTION; REPETITIVE SEQUENCES, NUCLEIC ACID; SEQUENCE DELETION;

EID: 16944363592     PISSN: 10614036     EISSN: None     Source Type: Journal    
DOI: 10.1038/ng1197-341     Document Type: Article

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