Lung cancer screening: Review and performance comparison under different risk scenarios

Lung

Volumn 192, Issue 1, 2014, Pages 55-63

  Tota, Joseph E ^a   Ramanakumar, Agnihotram V ^a   Franco, Eduardo L ^a  

^a MCGILL UNIVERSITY   (Canada)

Author keywords

Low dose computed tomography; Lung cancer; Performance; Screening

Indexed keywords

COST-BENEFIT ANALYSIS; DECISION SUPPORT TECHNIQUES; EARLY DETECTION OF CANCER; HEALTH CARE COSTS; HEALTH KNOWLEDGE, ATTITUDES, PRACTICE; HUMANS; LUNG NEOPLASMS; MASS SCREENING; PATIENT ACCEPTANCE OF HEALTH CARE; PATIENT SELECTION; PREDICTIVE VALUE OF TESTS; PREVALENCE; RISK ASSESSMENT; RISK FACTORS; SMOKING; SMOKING CESSATION; TOMOGRAPHY, X-RAY COMPUTED;

EID: 84894052348     PISSN: 03412040     EISSN: 14321750     Source Type: Journal    
DOI: 10.1007/s00408-013-9517-x     Document Type: Article

References (108)

1. Parkin DM, Bray F, Ferlay J, Pisani P (2005) Global cancer statistics, 2002. CA Cancer J Clin 55(2):74-108
2. Jemal A, Siegel R, Xu J, Ward E (2010) Cancer statistics, 2010. CA Cancer J Clin 60(5):277-300
3. Couraud S, Zalcman G, Milleron B, Morin F, Souquet PJ (2012) Lung cancer in never smokers: a review. Eur J Cancer 8:1299-1311
4. Eheman C, Henley SJ, Ballard-Barbash R, Jacobs EJ, Schymura MJ, Noone AM, Pan L, Anderson RN, Fulton JE, Kohler BA, Jemal A, Ward E, Plescia M, Ries LA, Edwards BK (2012) Annual Report to the Nation on the Status of Cancer, 1975-2008, featuring cancers associated with excess weight and lack of sufficient physical activity. Cancer 118(9):2338-2366
5. Peto R, Darby S, Deo H, Silcocks P, Whitley E, Doll R (2000) Smoking, smoking cessation, and lung cancer in the UK since 1950: combination of national statistics with two case-control studies. BMJ 321(7257):323-329
6. Halpern MT, Gillespie BW, Warner KE (1993) Patterns of absolute risk of lung cancer mortality in former smokers. J Natl Cancer Inst 85(6):457-464
7. Tong L, Spitz MR, Fueger JJ, Amos CA (1996) Lung carcinoma in former smokers. Cancer 78(5):1004-1010
8. Yang P, Allen MS, Aubry MC, Wampfler JA, Marks RS, Edell ES, Thibodeau S, Adjei AA, Jett J, Deschamps C (2005) Clinical features of 5,628 primary lung cancer patients: experience at Mayo Clinic from 1997 to 2003. Chest 128(1):452-462
9. Bach PB, Mirkin JN, Oliver TK, Azzoli CG, Berry DA, Brawley OW, Byers T, Colditz GA, Gould MK, Jett JR, Sabichi AL, Smith-Bindman R, Wood DE, Qaseem A, Detterbeck FC (2012) Benefits and harms of CT screening for lung cancer: a systematic review. JAMA 20:1-12
10. Pierce JP, Fiore MC, Novotny TE, Hatziandreu EJ, Davis RM (1989) Trends in cigarette smoking in the United States. Projections to the year 2000. JAMA 261(1):61-65
11. Crispo A, Brennan P, Jockel KH, Schaffrath-Rosario A, Wichmann HE, Nyberg F, Simonato L, Merletti F, Forastiere F, Boffetta P, Darby S (2004) The cumulative risk of lung cancer among current, ex- and never-smokers in European men. Br J Cancer 91(7):1280-1286
12. Godtfredsen NS, Prescott E, Osler M (2005) Effect of smoking reduction on lung cancer risk. JAMA 294(12):1505-1510
13. Alberg AJ, Ford JG, Samet JM (2007) Epidemiology of lung cancer: ACCP evidence-based clinical practice guidelines (2nd edn). Chest 132(3 Suppl):29S-55S
14. Haiman CA, Stram DO, Wilkens LR, Pike MC, Kolonel LN, Henderson BE, Le Marchand L (2006) Ethnic and racial differences in the smoking-related risk of lung cancer. N Engl J Med 354(4):333-342
15. Mazzone PJ, Chagoya JC, Arroliga AC (2005) Cause and effect in lung cancer: fueling the fire. Chest 128(1):6-8
16. Nitadori J, Inoue M, Iwasaki M, Otani T, Sasazuki S, Nagai K, Tsugane S (2006) Association between lung cancer incidence and family history of lung cancer: data from a large-scale population-based cohort study, the JPHC study. Chest 130(4):968-975
17. Hung RJ, Baragatti M, Thomas D, McKay J, Szeszenia-Dabrowska N, Zaridze D, Lissowska J, Rudnai P, Fabianova E, Mates D, Foretova L, Janout V, Bencko V, Chabrier A, Moullan N, Canzian F, Hall J, Boffetta P, Brennan P (2007) Inherited predisposition of lung cancer: a hierarchical modeling approach to DNA repair and cell cycle control pathways. Cancer Epidemiol Biomark Prev 16(12):2736-2744
18. Hung RJ, McKay JD, Gaborieau V, Boffetta P, Hashibe M, Zaridze D, Mukeria A, Szeszenia-Dabrowska N, Lissowska J, Rudnai P, Fabianova E, Mates D, Bencko V, Foretova L, Janout V, Chen C, Goodman G, Field JK, Liloglou T, Xinarianos G, Cassidy A, McLaughlin J, Liu G, Narod S, Krokan HE, Skorpen F, Elvestad MB, Hveem K, Vatten L, Linseisen J, Clavel-Chapelon F, Vineis P, Bueno-de-Mesquita HB, Lund E, Martinez C, Bingham S, Rasmuson T, Hainaut P, Riboli E, Ahrens W, Benhamou S, Lagiou P, Trichopoulos D, Holcatova I, Merletti F, Kjaerheim K, Agudo A, Macfarlane G, Talamini R, Simonato L, Lowry R, Conway DI, Znaor A, Healy C, Zelenika D, Boland A, Delepine M, Foglio M, Lechner D, Matsuda F, Blanche H, Gut I, Heath S, Lathrop M, Brennan P (2008) A susceptibility locus for lung cancer maps to nicotinic acetylcholine receptor subunit genes on 15q25. Nature 452(7187):633-637
19. Schwartz AG, Swanson GM (1997) Lung carcinoma in African Americans and Whites. A population-based study in metropolitan Detroit, Michigan. Cancer 79(1):45-52
20. Edwards BK, Ward E, Kohler BA, Eheman C, Zauber AG, Anderson RN, Jemal A, Schymura MJ, Lansdorp-Vogelaar I, Seeff LC, van Ballegooijen M, Goede SL, Ries LA (2010) Annual report to the nation on the status of cancer, 1975-2006, featuring colorectal cancer trends and impact of interventions (risk factors, screening, and treatment) to reduce future rates. Cancer 116(3):544-573
21. Smith L, Brinton LA, Spitz MR, Lam TK, Park Y, Hollenbeck AR, Freedman ND, Gierach GL (2012) Body mass index and risk of lung cancer among never, former, and current smokers. J Natl Cancer Inst 104:778-789
22. Veglia F, Vineis P, Overvad K, Boeing H, Bergmann M, Trichopoulou A, Trichopoulos D, Palli D, Krogh V, Tumino R, Linseisen J, Steindorf K, Raaschou-Nielsen O, Tjonneland A, Gonzalez CA, Martinez C, Dorronsoro M, Barricarte A, Cirera L, Quiros JR, Day NE, Saracci R, Riboli E (2007) Occupational exposures, environmental tobacco smoke, and lung cancer. Epidemiology 18(6):769-775
23. Kunst AE, Groenhof F, Mackenbach JP, Health EW (1998) Occupational class and cause specific mortality in middle aged men in 11 European countries: comparison of population based studies. EU Working Group on Socioeconomic Inequalities in Health. BMJ 316(7145):1636-1642
24. Ekberg-Aronsson M, Nilsson PM, Nilsson JA, Pehrsson K, Lofdahl CG (2006) Socio-economic status and lung cancer risk including histologic subtyping - a longitudinal study. Lung Cancer 51(1):21-29
25. Matukala Nkosi T, Parent ME, Siemiatycki J, Rousseau MC (2012) Socioeconomic position and lung cancer risk: how important is the modeling of smoking? Epidemiology 23(3):377-385
26. Saracci R (1977) Asbestos and lung cancer: an analysis of the epidemiological evidence on the asbestos-smoking interaction. Int J Cancer 20(3):323-331
27. Pershagen G, Akerblom G, Axelson O, Clavensjo B, Damber L, Desai G, Enflo A, Lagarde F, Mellander H, Svartengren M et al (1994) Residential radon exposure and lung cancer in Sweden. N Engl J Med 330(3):159-164
28. Shields PG, Harris CC (2000) Cancer risk and low-penetrance susceptibility genes in gene-environment interactions. J Clin Oncol 18(11):2309-2315
29. Ihsan R, Chauhan PS, Mishra AK, Yadav DS, Kaushal M, Sharma JD, Zomawia E, Verma Y, Kapur S, Saxena S (2011) Multiple analytical approaches reveal distinct gene-environment interactions in smokers and non smokers in lung cancer. PLoS ONE 6(12):e29431
30. Spitz MR, Gorlov IP, Dong Q, Wu X, Chen W, Chang DW, Etzel CJ, Caporaso NE, Zhao Y, Christiani DC, Brennan P, Albanes D, Shi J, Thun M, Landi MT, Amos CI (2012) Multistage analysis of variants in the inflammation pathway and lung cancer risk in smokers. Cancer Epidemiol Biomark Prev 21(7):1213-1221
31. Wilson JM, Jungner YG (1968) Principles and practice of mass screening for disease. Bol Oficina Sanit Panam 65(4):281-393
32. Black WC (2007) Computed tomography screening for lung cancer: review of screening principles and update on current status. Cancer 110(11):2370-2384
33. McWilliams A, MacAulay C, Gazdar AF, Lam S (2002) Innovative molecular and imaging approaches for the detection of lung cancer and its precursor lesions. Oncogene 21(45):6949-6959
34. Ganti AK, Mulshine JL (2006) Lung cancer screening. Oncologist 11(5):481-487
35. Smith RA, Cokkinides V, Brawley OW (2012) Cancer screening in the United States, 2012: a review of current American Cancer Society guidelines and current issues in cancer screening. CA Cancer J Clin 62:129-142
36. Kubik A, Parkin DM, Khlat M, Erban J, Polak J, Adamec M (1990) Lack of benefit from semi-annual screening for cancer of the lung: follow-up report of a randomized controlled trial on a population of high-risk males in Czechoslovakia. Int J Cancer 45(1):26-33
37. Fontana RS, Sanderson DR, Woolner LB, Taylor WF, Miller WE, Muhm JR, Bernatz PE, Payne WS, Pairolero PC, Bergstralh EJ (1991) Screening for lung cancer. A critique of the Mayo Lung Project. Cancer 67(4 Suppl):1155-1164
38. Fontana RS, Sanderson DR, Woolner LB, Taylor WF, Miller WE, Muhm JR (1986) Lung cancer screening: the Mayo program. J Occup Med 28(8):746-750
39. Melamed MR, Flehinger BJ, Zaman MB (1987) Impact of early detection on the clinical course of lung cancer. Surg Clin N Am 67(5):909-924
40. Brett GZ (1969) Earlier diagnosis and survival in lung cancer. Br Med J 4(5678):260-262
41. Melamed MR, Flehinger BJ, Zaman MB, Heelan RT, Perchick WA, Martini N (1984) Screening for early lung cancer. Results of the Memorial Sloan-Kettering study in New York. Chest 86(1):44-53
42. Oken MM, Hocking WG, Kvale PA, Andriole GL, Buys SS, Church TR, Crawford ED, Fouad MN, Isaacs C, Reding DJ, Weissfeld JL, Yokochi LA, O'Brien B, Ragard LR, Rathmell JM, Riley TL, Wright P, Caparaso N, Hu P, Izmirlian G, Pinsky PF, Prorok PC, Kramer BS, Miller AB, Gohagan JK, Berg CD (2011) Screening by chest radiograph and lung cancer mortality: the Prostate, Lung, Colorectal, and Ovarian (PLCO) randomized trial. JAMA 306(17):1865-1873
43. McWilliams A, Lam S (2005) Lung cancer screening. Curr Opin Pulm Med 11(4):272-277
44. Black WC (2000) Overdiagnosis: an underrecognized cause of confusion and harm in cancer screening. J Natl Cancer Inst 92(16):1280-1282
45. Welch HG, Black WC (2010) Overdiagnosis in cancer. J Natl Cancer Inst 102(9):605-613
46. Aberle DR, Berg CD, Black WC, Church TR, Fagerstrom RM, Galen B, Gareen IF, Gatsonis C, Goldin J, Gohagan JK, Hillman B, Jaffe C, Kramer BS, Lynch D, Marcus PM, Schnall M, Sullivan DC, Sullivan D, Zylak CJ (2011) The National Lung Screening Trial: overview and study design. Radiology 258(1):243-253
47. Aberle DR, Adams AM, Berg CD, Black WC, Clapp JD, Fagerstrom RM, Gareen IF, Gatsonis C, Marcus PM, Sicks JD (2011) Reduced lung-cancer mortality with low-dose computed tomographic screening. N Engl J Med 365(5):395-409
48. Infante M, Cavuto S, Lutman FR, Brambilla G, Chiesa G, Ceresoli G, Passera E, Angeli E, Chiarenza M, Aranzulla G, Cariboni U, Errico V, Inzirillo F, Bottoni E, Voulaz E, Alloisio M, Destro A, Roncalli M, Santoro A, Ravasi G (2009) A randomized study of lung cancer screening with spiral computed tomography: three-year results from the DANTE trial. Am J Respir Crit Care Med 180(5):445-453
49. van Iersel CA, de Koning HJ, Draisma G, Mali WP, Scholten ET, Nackaerts K, Prokop M, Habbema JD, Oudkerk M, van Klaveren RJ (2007) Risk-based selection from the general population in a screening trial: selection criteria, recruitment and power for the Dutch-Belgian randomised lung cancer multi-slice CT screening trial (NELSON). Int J Cancer 120(4):868-874
50. Pedersen JH, Ashraf H, Dirksen A, Bach K, Hansen H, Toennesen P, Thorsen H, Brodersen J, Skov BG, Dossing M, Mortensen J, Richter K, Clementsen P, Seersholm N (2009) The Danish randomized lung cancer CT screening trial - overall design and results of the prevalence round. J Thorac Oncol 4(5):608-614
51. Lopes Pegna A, Picozzi G, Mascalchi M, Maria Carozzi F, Carrozzi L, Comin C, Spinelli C, Falaschi F, Grazzini M, Innocenti F, Ronchi C, Paci E (2009) Design, recruitment and baseline results of the ITALUNG trial for lung cancer screening with low-dose CT. Lung Cancer 64(1):34-40
52. Marchiano A, Calabro E, Civelli E, Di Tolla G, Frigerio LF, Morosi C, Tafaro F, Ferri E, Sverzellati N, Camerini T, Mariani L, Lo Vullo S, Pastorino U (2009) Pulmonary nodules: volume repeatability at multidetector CT lung cancer screening. Radiology 251(3):919-925
53. Baldwin DR, Duffy SW, Wald NJ, Page R, Hansell DM, Field JK (2011) UK Lung Screen (UKLS) nodule management protocol: modelling of a single screen randomised controlled trial of low-dose CT screening for lung cancer. Thorax 66(4):308-313
54. Humphrey LL, Teutsch S, Johnson M (2004) Lung cancer screening with sputum cytologic examination, chest radiography, and computed tomography: an update for the U.S. Preventive Services Task Force. Ann Intern Med 140(9):740-753
55. U.S. Preventive Services Task Force (2004) Lung cancer screening: recommendation statement. Ann Intern Med 140(9):738-739
56. Bach PB, Silvestri GA, Hanger M, Jett JR (2007) Screening for lung cancer: ACCP evidence-based clinical practice guidelines (2nd edn). Chest 132(3 Suppl):69S-77S
57. Smith RA, Cokkinides V, Brooks D, Saslow D, Brawley OW (2010) Cancer screening in the United States, 2010: a review of current American Cancer Society guidelines and issues in cancer screening. CA Cancer J Clin 60(2):99-119
58. Wender R, Fontham ET, Barrera E Jr, Colditz GA, Church TR, Ettinger DS, Etzioni R, Flowers CR, Gazelle GS, Kelsey DK, Lamonte SJ, Michaelson JS, Oeffinger KC, Shih YC, Sullivan DC, Travis W, Walter L, Wolf AM, Brawley OW, Smith RA (2013) American Cancer Society lung cancer screening guidelines. CA Cancer J Clin 6:107-117
59. Doll R, Peto R (1978) Cigarette smoking and bronchial carcinoma: dose and time relationships among regular smokers and lifelong non-smokers. J Epidemiol Community Health 32(4):303-313
60. Prindiville SA, Byers T, Hirsch FR, Franklin WA, Miller YE, Vu KO, Wolf HJ, Baron AE, Shroyer KR, Zeng C, Kennedy TC, Bunn PA (2003) Sputum cytological atypia as a predictor of incident lung cancer in a cohort of heavy smokers with airflow obstruction. Cancer Epidemiol Biomark Prev 12(10):987-993
61. Bach PB, Kattan MW, Thornquist MD, Kris MG, Tate RC, Barnett MJ, Hsieh LJ, Begg CB (2003) Variations in lung cancer risk among smokers. J Natl Cancer Inst 95(6):470-478
62. Cassidy A, Duffy SW, Myles JP, Liloglou T, Field JK (2007) Lung cancer risk prediction: a tool for early detection. Int J Cancer 120(1):1-6
63. Spitz MR, Hong WK, Amos CI, Wu X, Schabath MB, Dong Q, Shete S, Etzel CJ (2007) A risk model for prediction of lung cancer. J Natl Cancer Inst 99(9):715-726
64. Cassidy A, Myles JP, van Tongeren M, Page RD, Liloglou T, Duffy SW, Field JK (2008) The LLP risk model: an individual risk prediction model for lung cancer. Br J Cancer 98(2):270-276
65. Spitz MR, Etzel CJ, Dong Q, Amos CI, Wei Q, Wu X, Hong WK (2008) An expanded risk prediction model for lung cancer. Cancer Prev Res (Phila) 1(4):250-254
66. Etzel CJ, Kachroo S, Liu M, D'Amelio A, Dong Q, Cote ML, Wenzlaff AS, Hong WK, Greisinger AJ, Schwartz AG, Spitz MR (2008) Development and validation of a lung cancer risk prediction model for African-Americans. Cancer Prev Res (Phila) 1(4):255-265
67. Tammemagi CM, Pinsky PF, Caporaso NE, Kvale PA, Hocking WG, Church TR, Riley TL, Commins J, Oken MM, Berg CD, Prorok PC (2011) Lung cancer risk prediction: Prostate, Lung, Colorectal And Ovarian Cancer Screening Trial models and validation. J Natl Cancer Inst 103(13):1058-1068
68. Raji OY, Duffy SW, Agbaje OF, Baker SG, Christiani DC, Cassidy A, Field JK (2012) Predictive accuracy of the Liverpool Lung Project risk model for stratifying patients for computed tomography screening for lung cancer: a case-control and cohort validation study. Ann Intern Med 157(4):242-250
69. Tammemagi MC, Katki HA, Hocking WG, Church TR, Caporaso N, Kvale PA, Chaturvedi AK, Silvestri GA, Riley TL, Commins J, Berg CD (2013) Selection criteria for lung-cancer screening. N Engl J Med 368(8):728-736
70. Tammemagi MC, Lam SC, McWilliams AM, Sin DD (2011) Incremental value of pulmonary function and sputum DNA image cytometry in lung cancer risk prediction. Cancer Prev Res (Phila) 4(4):552-561
71. Yee J, Sadar MD, Sin DD, Kuzyk M, Xing L, Kondra J, McWilliams A, Man SF, Lam S (2009) Connective tissue-activating peptide III: a novel blood biomarker for early lung cancer detection. J Clin Oncol 27(17):2787-2792
72. Church TR, Anderson KE, Caporaso NE, Geisser MS, Le CT, Zhang Y, Benoit AR, Carmella SG, Hecht SS (2009) A prospectively measured serum biomarker for a tobacco-specific carcinogen and lung cancer in smokers. Cancer Epidemiol Biomark Prev 18(1):260-266
73. Chaturvedi AK, Caporaso NE, Katki HA, Wong HL, Chatterjee N, Pine SR, Chanock SJ, Goedert JJ, Engels EA (2010) C-reactive protein and risk of lung cancer. J Clin Oncol 28(16):2719-2726
74. Amos CI, Wu X, Broderick P, Gorlov IP, Gu J, Eisen T, Dong Q, Zhang Q, Gu X, Vijayakrishnan J, Sullivan K, Matakidou A, Wang Y, Mills G, Doheny K, Tsai YY, Chen WV, Shete S, Spitz MR, Houlston RS (2008) Genome-wide association scan of tag SNPs identifies a susceptibility locus for lung cancer at 15q25.1. Nat Genet 40(5):616-622
75. Thorgeirsson TE, Geller F, Sulem P, Rafnar T, Wiste A, Magnusson KP, Manolescu A, Thorleifsson G, Stefansson H, Ingason A, Stacey SN, Bergthorsson JT, Thorlacius S, Gudmundsson J, Jonsson T, Jakobsdottir M, Saemundsdottir J, Olafsdottir O, Gudmundsson LJ, Bjornsdottir G, Kristjansson K, Skuladottir H, Isaksson HJ, Gudbjartsson T, Jones GT, Mueller T, Gottsater A, Flex A, Aben KK, de Vegt F, Mulders PF, Isla D, Vidal MJ, Asin L, Saez B, Murillo L, Blondal T, Kolbeinsson H, Stefansson JG, Hansdottir I, Runarsdottir V, Pola R, Lindblad B, van Rij AM, Dieplinger B, Haltmayer M, Mayordomo JI, Kiemeney LA, Matthiasson SE, Oskarsson H, Tyrfingsson T, Gudbjartsson DF, Gulcher JR, Jonsson S, Thorsteinsdottir U, Kong A, Stefansson K (2008) A variant associated with nicotine dependence, lung cancer and peripheral arterial disease. Nature 452(7187):638-642
76. McKay JD, Hung RJ, Gaborieau V, Boffetta P, Chabrier A, Byrnes G, Zaridze D, Mukeria A, Szeszenia-Dabrowska N, Lissowska J, Rudnai P, Fabianova E, Mates D, Bencko V, Foretova L, Janout V, McLaughlin J, Shepherd F, Montpetit A, Narod S, Krokan HE, Skorpen F, Elvestad MB, Vatten L, Njolstad I, Axelsson T, Chen C, Goodman G, Barnett M, Loomis MM, Lubinski J, Matyjasik J, Lener M, Oszutowska D, Field J, Liloglou T, Xinarianos G, Cassidy A, Vineis P, Clavel-Chapelon F, Palli D, Tumino R, Krogh V, Panico S, Gonzalez CA, Ramon Quiros J, Martinez C, Navarro C, Ardanaz E, Larranaga N, Kham KT, Key T, Bueno-de-Mesquita HB, Peeters PH, Trichopoulou A, Linseisen J, Boeing H, Hallmans G, Overvad K, Tjonneland A, Kumle M, Riboli E, Zelenika D, Boland A, Delepine M, Foglio M, Lechner D, Matsuda F, Blanche H, Gut I, Heath S, Lathrop M, Brennan P (2008) Lung cancer susceptibility locus at 5p15.33. Nat Genet 40(12):1404-1406
77. Wang Y, Broderick P, Webb E, Wu X, Vijayakrishnan J, Matakidou A, Qureshi M, Dong Q, Gu X, Chen WV, Spitz MR, Eisen T, Amos CI, Houlston RS (2008) Common 5p15.33 and 6p21.33 variants influence lung cancer risk. Nat Genet 40(12):1407-1409
78. Landi MT, Chatterjee N, Yu K, Goldin LR, Goldstein AM, Rotunno M, Mirabello L, Jacobs K, Wheeler W, Yeager M, Bergen AW, Li Q, Consonni D, Pesatori AC, Wacholder S, Thun M, Diver R, Oken M, Virtamo J, Albanes D, Wang Z, Burdette L, Doheny KF, Pugh EW, Laurie C, Brennan P, Hung R, Gaborieau V, McKay JD, Lathrop M, McLaughlin J, Wang Y, Tsao MS, Spitz MR, Krokan H, Vatten L, Skorpen F, Arnesen E, Benhamou S, Bouchard C, Metspalu A, Vooder T, Nelis M, Valk K, Field JK, Chen C, Goodman G, Sulem P, Thorleifsson G, Rafnar T, Eisen T, Sauter W, Rosenberger A, Bickeboller H, Risch A, Chang-Claude J, Wichmann HE, Stefansson K, Houlston R, Amos CI, Fraumeni JF Jr, Savage SA, Bertazzi PA, Tucker MA, Chanock S, Caporaso NE (2009) A genome-wide association study of lung cancer identifies a region of chromosome 5p15 associated with risk for adenocarcinoma. Am J Hum Genet 85(5):679-691
79. Rafnar T, Sulem P, Stacey SN, Geller F, Gudmundsson J, Sigurdsson A, Jakobsdottir M, Helgadottir H, Thorlacius S, Aben KK, Blondal T, Thorgeirsson TE, Thorleifsson G, Kristjansson K, Thorisdottir K, Ragnarsson R, Sigurgeirsson B, Skuladottir H, Gudbjartsson T, Isaksson HJ, Einarsson GV, Benediktsdottir KR, Agnarsson BA, Olafsson K, Salvarsdottir A, Bjarnason H, Asgeirsdottir M, Kristinsson KT, Matthiasdottir S, Sveinsdottir SG, Polidoro S, Hoiom V, Botella-Estrada R, Hemminki K, Rudnai P, Bishop DT, Campagna M, Kellen E, Zeegers MP, de Verdier P, Ferrer A, Isla D, Vidal MJ, Andres R, Saez B, Juberias P, Banzo J, Navarrete S, Tres A, Kan D, Lindblom A, Gurzau E, Koppova K, de Vegt F, Schalken JA, van der Heijden HF, Smit HJ, Termeer RA, Oosterwijk E, van Hooij O, Nagore E, Porru S, Steineck G, Hansson J, Buntinx F, Catalona WJ, Matullo G, Vineis P, Kiltie AE, Mayordomo JI, Kumar R, Kiemeney LA, Frigge ML, Jonsson T, Saemundsson H, Barkardottir RB, Jonsson E, Jonsson S, Olafsson JH, Gulcher JR, Masson G, Gudbjartsson DF, Kong A, Thorsteinsdottir U, Stefansson K (2009) Sequence variants at the TERT-CLPTM1L locus associate with many cancer types. Nat Genet 41(2):221-227
80. Gail MH, Brinton LA, Byar DP, Corle DK, Green SB, Schairer C, Mulvihill JJ (1989) Projecting individualized probabilities of developing breast cancer for white females who are being examined annually. J Natl Cancer Inst 81(24):1879-1886
81. Decarli A, Calza S, Masala G, Specchia C, Palli D, Gail MH (2006) Gail model for prediction of absolute risk of invasive breast cancer: independent evaluation in the Florence-European Prospective Investigation Into Cancer and Nutrition cohort. J Natl Cancer Inst 98(23):1686-1693
82. Marshall D, Simpson KN, Earle CC, Chu C (2001) Potential cost-effectiveness of one-time screening for lung cancer (LC) in a high risk cohort. Lung Cancer 32(3):227-236
83. Chirikos TN, Hazelton T, Tockman M, Clark R (2002) Screening for lung cancer with CT: a preliminary cost-effectiveness analysis. Chest 121(5):1507-1514
84. Wisnivesky JP, Mushlin AI, Sicherman N, Henschke C (2003) The cost-effectiveness of low-dose CT screening for lung cancer: preliminary results of baseline screening. Chest 124(2):614-621
85. Mahadevia PJ, Fleisher LA, Frick KD, Eng J, Goodman SN, Powe NR (2003) Lung cancer screening with helical computed tomography in older adult smokers: a decision and cost-effectiveness analysis. JAMA 289(3):313-322
86. Manser R, Dalton A, Carter R, Byrnes G, Elwood M, Campbell DA (2005) Cost-effectiveness analysis of screening for lung cancer with low dose spiral CT (computed tomography) in the Australian setting. Lung Cancer 48(2):171-185
87. McMahon PM, Kong CY, Bouzan C, Weinstein MC, Cipriano LE, Tramontano AC, Johnson BE, Weeks JC, Gazelle GS (2011) Cost-effectiveness of computed tomography screening for lung cancer in the United States. J Thorac Oncol 6(11):1841-1848
88. Goulart BH, Bensink ME, Mummy DG, Ramsey SD (2012) Lung cancer screening with low-dose computed tomography: costs, national expenditures, and cost-effectiveness. J Natl Compr Cancer Netw 10(2):267-275
89. Pyenson BS, Sander MS, Jiang Y, Kahn H, Mulshine JL (2012) An actuarial analysis shows that offering lung cancer screening as an insurance benefit would save lives at relatively low cost. Health Aff (Millwood) 31(4):770-779
90. Silvestri GA, Nietert PJ, Zoller J, Carter C, Bradford D (2007) Attitudes towards screening for lung cancer among smokers and their non-smoking counterparts. Thorax 62(2):126-130
91. Patel D, Akporobaro A, Chinyanganya N, Hackshaw A, Seale C, Spiro SG, Griffiths C (2012) Attitudes to participation in a lung cancer screening trial: a qualitative study. Thorax 67(5):418-425
92. CDC (2010) Vital signs: current cigarette smoking among adults aged ≥ 18 years - United States, 2009. Morb Mortal Wkly Rep 59(35):1135-1140
93. Franco EL, Cuzick J, Hildesheim A, de Sanjose S (2006) Chapter 20: issues in planning cervical cancer screening in the era of HPV vaccination. Vaccine 24(Suppl 3):S3/171-S3/177
94. Jonnalagadda S, Bergamo C, Lin JJ, Lurslurchachai L, Diefenbach M, Smith C, Nelson JE, Wisnivesky JP (2012) Beliefs and attitudes about lung cancer screening among smokers. Lung Cancer 77:526-531
95. Franco EL, Mahmud SM, Tota J, Ferenczy A, Coutlee F (2009) The expected impact of HPV vaccination on the accuracy of cervical cancer screening: the need for a paradigm change. Arch Med Res 40(6):478-485
96. Toyoda Y, Nakayama T, Kusunoki Y, Iso H, Suzuki T (2008) Sensitivity and specificity of lung cancer screening using chest low-dose computed tomography. Br J Cancer 98(10):1602-1607
97. Clin B, Morlais F, Guittet L, Gislard A, Marquignon MF, Paris C, Caillard JF, Launoy G, Letourneux M (2009) Performance of chest radiograph and CT scan for lung cancer screening in asbestos-exposed workers. Occup Environ Med 66(8):529-534
98. van Klaveren RJ, Oudkerk M, Prokop M, Scholten ET, Nackaerts K, Vernhout R, van Iersel CA, van den Bergh KA, van't Westeinde S, van der Aalst C, Thunnissen E, Xu DM, Wang Y, Zhao Y, Gietema HA, de Hoop BJ, Groen HJ, de Bock GH, van Ooijen P, Weenink C, Verschakelen J, Lammers JW, Timens W, Willebrand D, Vink A, Mali W, de Koning HJ (2009) Management of lung nodules detected by volume CT scanning. N Engl J Med 361(23):2221-2229
99. Menezes RJ, Roberts HC, Paul NS, McGregor M, Chung TB, Patsios D, Weisbrod G, Herman S, Pereira A, McGregor A, Dong Z, Sitartchouk I, Boerner S, Tsao MS, Keshavjee S, Shepherd FA (2010) Lung cancer screening using low-dose computed tomography in at-risk individuals: the Toronto experience. Lung Cancer 67(2):177-183
100. Taylor KL, Cox LS, Zincke N, Mehta L, McGuire C, Gelmann E (2007) Lung cancer screening as a teachable moment for smoking cessation. Lung Cancer 56(1):125-134
101. van der Aalst CM, van den Bergh KA, Willemsen MC, de Koning HJ, van Klaveren RJ (2010) Lung cancer screening and smoking abstinence: 2 year follow-up data from the Dutch-Belgian randomised controlled lung cancer screening trial. Thorax 65(7):600-605
102. Kovalchik SA, Tammemagi M, Berg CD, Caporaso NE, Riley TL, Korch M, Silvestri GA, Chaturvedi AK, Katki HA (2013) Targeting of low-dose CT screening according to the risk of lung-cancer death. N Engl J Med 369(3):245-254
103. Esserman LJ, Thompson IM Jr, Reid B (2013) Overdiagnosis and overtreatment in cancer: an opportunity for improvement. JAMA 310(8):797-798
104. McWilliams A, Tammemagi MC, Mayo JR, Roberts H, Liu G, Soghrati K, Yasufuku K, Martel S, Laberge F, Gingras M, Atkar-Khattra S, Berg CD, Evans K, Finley R, Yee J, English J, Nasute P, Goffin J, Puksa S, Stewart L, Tsai S, Johnston MR, Manos D, Nicholas G, Goss GD, Seely JM, Amjadi K, Tremblay A, Burrowes P, MacEachern P, Bhatia R, Tsao MS, Lam S (2013) Probability of cancer in pulmonary nodules detected on first screening CT. N Engl J Med 369(10):910-919
105. Cox LS, Clark MM, Jett JR, Patten CA, Schroeder DR, Nirelli LM, Swensen SJ, Hurt RD (2003) Change in smoking status after spiral chest computed tomography scan screening. Cancer 98(11):2495-2501
106. Townsend CO, Clark MM, Jett JR, Patten CA, Schroeder DR, Nirelli LM, Swensen SJ, Hurt RD (2005) Relation between smoking cessation and receiving results from three annual spiral chest computed tomography scans for lung carcinoma screening. Cancer 103(10):2154-2162
107. Ashraf H, Tonnesen P, Holst PJ, Dirksen A, Thorsen H, Dossing M (2009) Effect of CT screening on smoking habits at 1-year follow-up in the Danish Lung Cancer Screening Trial (DLCST). Thorax 64(5):388-392
108. Jett JR, Midthun DE (2011) Screening for lung cancer: for patients at increased risk for lung cancer, it works. Ann Intern Med 155(8):540-542