δ-Opioid receptor activation stimulates normal diet intake but conversely suppresses high-fat diet intake in mice

American Journal of Physiology - Regulatory Integrative and Comparative Physiology

Volumn 306, Issue 4, 2014, Pages

  Kaneko, Kentaro ^a   Mizushige, Takafumi ^a   Miyazaki, Yuri ^a   Lazarus, Michael ^b,c   Urade, Yoshihiro ^b,c   Yoshikawa, Masaaki ^a   Kanamoto, Ryuhei ^a   Ohinata, Kousaku ^a  

^a KYOTO UNIVERSITY   (Japan)

^b OSAKA BIOSCIENCE INSTITUTE   (Japan)

^c UNIVERSITY OF TSUKUBA   (Japan)

Author keywords

opioid receptor; CRF; Food intake; MC4; PGD2

Indexed keywords

CRF; FOOD INTAKE; MC4; PGD2; Δ-OPIOID RECEPTOR;

ANALGESICS, OPIOID; ANIMALS; CYCLOOXYGENASE INHIBITORS; DIET, HIGH-FAT; EATING; ENKEPHALIN, D-PENICILLAMINE (2,5)-; MALE; MICE; PYRAZOLES; RECEPTORS, OPIOID, DELTA; RECEPTORS, PROSTAGLANDIN; SULFONAMIDES;

EID: 84894052324     PISSN: 03636119     EISSN: 15221490     Source Type: Journal    
DOI: 10.1152/ajpregu.00405.2013     Document Type: Article

References (45)

1. Asakawa A, Inui A, Momose K, Ueno N, Fujino MA, Kasuga M. Endorphins have orexigenic and anxiolytic activities in mice. Neuroreport 9: 2265-2267, 1998.
2. Butler AA, Marks DL, Fan W, Kuhn CM, Bartolome M, Cone RD. Melanocortin-4 receptor is required for acute homeostatic responses to increased dietary fat. Nat Neurosci 4: 605-611, 2001.
3. Bzdega T, Chin H, Kim H, Jung HH, Kozak CA, Klee WA. Regional expression and chromosomal localization of the delta opiate receptor gene. Proc Natl Acad Sci USA 90: 9305-9309, 1993.
4. Carpino LA, Han GY. The 9-fluorenylmethoxycarbonyl function, a new base-sensitive amino-protecting group. J Am Chem 92: 5748-5749, 1970.
5. Clegg DJ, Benoit SC, Air EL, Jackman A, Tso P, D'Alessio D, Woods SC, Seeley RJ. Increased dietary fat attenuates the anorexic effects of intracerebroventricular injections of MTII. Endocrinology 144: 2941-2946, 2003.
6. Cole JL, Berman N, Bodnar RJ. Evaluation of chronic opioid receptor antagonist effects upon weight and intake measures in lean and obese Zucker rats. Peptides 18: 1201-1207, 1997.
7. Cole JL, Leventhal L, Pasternak GW, Bowen WD, Bodnar RJ. Reductions in body weight following chronic central opioid receptor subtype antagonists during development of dietary obesity in rats. Brain Res 678: 168-176, 1995.
8. Cowley MA, Pronchuk N, Fan W, Dinulescu DM, Colmers WF, Cone RD. Integration of NPY, AGRP, and melanocortin signals in the hypothalamic paraventricular nucleus: evidence of a cellular basis for the adipostat. Neuron 24: 155-163, 1999.
9. Czyzyk TA, Romero-Picó A, Pintar J, McKinzie JH, Tschöp MH, Statnick MA, Nogueiras R. Mice lacking δ-opioid receptors resist the development of diet-induced obesity. FASEB J 26: 3483-3492, 2012.
10. Erlanson-Albertsson C, York D. Enterostatin-a peptide regulating fat intake. Obes Res 5: 360-372, 1997.
11. Garza JC, Kim CS, Liu J, Zhang W, Lu XY. Adeno-associated virus-mediated knockdown of melanocortin-4 receptor in the paraventricular nucleus of the hypothalamus promotes high-fat diet-induced hyperphagia, and obesity. J Endocrinol 197: 471-482, 2008.
12. Gelez H, Poirier S, Facchinetti P, Allers KA, Wayman C, Bernabé J, Alexandre L, Giuliano F. Neuroanatomical distribution of the melanocortin-4 receptors in male and female rodent brain. J Chem Neuroanat 40: 310-324, 2010.
13. Gray AC, Coupar IM, White PJ. Comparison of opioid receptor distributions in the rat central nervous system. Life Sci 79: 674-685, 2006.
14. Hou IC, Yoshikawa M, Ohinata K. β-Lactotensin derived from bovine β-lactoglobulin suppresses food intake via the CRF system followed by the CGRP system in mice. Peptides 30: 2228-2232, 2009.
15. Huszar D, Lynch CA, Fairchild-Huntress V, Dunmore JH, Fang Q, Berkemeier LR, Gu W, Kesterson RA, Boston BA, Cone RD, Smith FJ, Campfield LA, Burn P, Lee F. Targeted disruption of the melanocortin-4 receptor results in obesity in mice. Cell 88: 131-141, 1997.
16. Inui A, Asakawa A, Bowers CY, Mantovani G, Laviano A, Meguid MM, Fujimiya M. Ghrelin, appetite, and gastric motility: the emerging role of the stomach as an endocrine organ. FASEB J 18: 439-456, 2004.
17. B systems. Am J Physiol Gastrointest Liver Physiol 299: G799-G805, 2010.
18. Kaneko K, Lazarus M, Miyamoto C, Oishi Y, Nagata N, Yang S, Yoshikawa M, Aritake K, Furuyashiki T, Narumiya S, Urade Y, Ohinata K. Orally administered rubiscolin-6, a γ opioid peptide derived from Rubisco, stimulates food intake via leptomeningeal lipocallin-type prostaglandin D synthase in mice. Mol Nutr Food Res 56: 1315-1323, 2012.
19. 2-NPY system-involvement in orally active orexigenic d opioid peptide. Neuropeptides 6: 353-357, 2012.
20. Kask A, Mutulis F, Muceniece R, Pähkla R, Mutule I, Wikberg JE, Rägo L, Schiöth HB. Discovery of a novel superpotent and selective melanocortin-4 receptor antagonist (HS024): evaluation in vitro and in vivo. Endocrinology 139: 5006-5014, 1998.
21. Kawashima S, Sakihara S, Kageyama K, Nigawara T, Suda T. Corticotropin-releasing factor (CRF) is involved in the acute anorexic effect of α-melanocyte-stimulating hormone: a study using CRF-deficient mice. Peptides 29: 2169-2174, 2008.
22. Kishi T, Aschkenasi CJ, Choi BJ, Lopez ME, Lee CE, Liu H, Hollenberg AN, Friedman JM, Elmquist JK. Neuropeptide YY1 receptor mRNA in rodent brain: distribution, and colocalization with melanocortin-4 receptor. J Comp Neurol 482: 217-243, 2005.
23. Kishi T, Aschkenasi CJ, Lee CE, Mountjoy KG, Saper CB, Elmquist JK. Expression of melanocortin 4 receptor mRNA in the central nervous system of the rat. J Comp Neurol 457: 213-235, 2003.
24. Kishi T, Elmquist JK. Body weight is regulated by brain: a link between feeding, and emotion. Mol Psychiatry 10: 132-146, 2005.
25. Legendre A, Papakonstantinou E, Roy MC, Richard D, Harris RB. Differences in response to corticotropin-releasing factor after short-and long-term consumption of a high-fat diet. Am J Physiol Regul Integr Comp Physiol 293: R1076-R1085, 2007.
26. Lu XY, Barsh GS, Akil H, Watson SJ. Interaction between alphamelanocyte-stimulating hormone and corticotropin-releasing hormone in the regulation of feeding and hypothalamo-pituitary-adrenal responses. J Neurosci 23: 7863-7872, 2003.
27. Mansour A, Fox CA, Akil H, Watson SJ. Opioid-receptor mRNA expression in the rat CNS: anatomical and functional implications. Trends Neurosci 18: 22-29, 1995.
28. 2 as a mediator of allergic asthma. Science 287: 2013-2017, 2000.
29. McMinn JE, Wilkinson CW, Havel PJ, Woods SC, Schwartz MW. Effect of intracerebroventricular α-MSH on food intake, adiposity, c-Fos induction, and neuropeptide expression. Am J Physiol Regul Integr Comp Physiol 279: R695-R703, 2000.
30. Mizoguchi A, Eguchi N, Kimura K, Kiyohara Y, Qu WM, Huang ZL, Mochizuki T, Lazarus M, Kobayashi T, Kaneko T, Narumiya S, Urade Y, Hayaishi O. Dominant localization of prostaglandin D receptors on arachnoid trabecular cells in mouse basal forebrain and their involvement in the regulation of nonrapid eye movement sleep. Proc Natl Acad Sci USA 98: 11674-11679, 2001.
31. Morton GJ, Cummings DE, Baskin DG, Barsh GS, Schwartz MW. Central nervous system control of food intake, and body weight. Nature 443: 289-295, 2006.
32. Negri L, Noviello L, Noviello V. Effects of sauvagine, urotensin I and CRF on food intake in rats. Peptides 6, Suppl 3: 53-57, 2006.
33. Ohinata K, Fujiwara Y, Fukumoto S, Iwai M, Horiuchi M, Yoshikawa M. Angiotensin II and III suppress food intake via angiotensin AT2 receptor and prostaglandin EP4 receptor in mice. FEBS Lett 582: 773-777, 2008.
34. Ohinata K, Inui A, Asakawa A, Wada K, Wada E, Yoshikawa M. Albutensin A and complement C3a decrease food intake in mice. Peptides 23: 127-133, 2002.
35. 2-dependent mechanism in mice. Peptides 30: 1105-1108, 2009.
36. Ohinata K, Suetsugu K, Fujiwara Y, Yoshikawa M. Activation of prostaglandin E receptor EP4 subtype suppresses food intake in mice. Prostaglandins Other Lipid Mediat 81: 31-36, 2006.
37. 5]-oryzatensin(5-9). Peptides 28: 602-606, 2007.
38. 2 stimulates food intake via the neuropeptide Y system in mice. FEBS Lett 582: 679-684, 2008.
39. 2 synthase knock-out mice. J Biol Chem 280: 29946-29955, 2005.
40. Scherrer G, Tryoen-Tóth P, Filliol D, Matifas A, Laustriat D, Cao YQ, Basbaum AI, Dierich A, Vonesh JL, Gavériaux-Ruff C, Kieffer BL. Knockin mice expressing fluorescent delta-opioid receptors uncover G protein-coupled receptor dynamics in vivo. Proc Natl Acad Sci USA 103: 9691-9696.
41. Schwartz MW, Woods SC, Porte DJr Seeley RJ, Baskin DG. Central nervous system control of food intake. Nature 404: 661-671, 2000.
42. Srisai D, Gillum MP, Panaro BL, Zhang XM, Kotchabhakdi N, Shulman GI, Ellacott KL, Cone RD. Characterization of the hyperphagic response to dietary fat in the MC4R knockout mouse. Endocrinology 152: 890-902, 2011.
43. Tanaka R, Miwa Y, Mou K, Tomikawa M, Eguchi N, Urade Y, Takahashi-Yanaga F, Morimoto S, Wake N, Sasaguri T. Knockout of the l-pgds gene aggravates obesity and atherosclerosis in mice. Biochem Biophys Res Commun 378: 851-856, 2009.
44. Xu Y, Elmquist JK, Fukuda M. Central nervous control of energy, and glucose balance: focus on the central melanocortin system. Ann NY Acad Sci 1243: 1-14, 2011.
45. Zhang M, Kelley AE. Enhanced intake of high-fat food following striatal mu-opioid stimulation: microinjection mapping and fos expression. Neuroscience 99: 267-277, 2000.