Orally administered rubiscolin-6, a δ opioid peptide derived from Rubisco, stimulates food intake via leptomeningeal lipocallin-type prostaglandin D synthase in mice

Molecular Nutrition and Food Research

Volumn 56, Issue 8, 2012, Pages 1315-1323

  Kaneko, Kentaro ^a   Lazarus, Michael ^b   Miyamoto, Chihiro ^a   Oishi, Yo ^b   Nagata, Nanae ^b   Yang, Shuzhang ^a   Yoshikawa, Masaaki ^c   Aritake, Kosuke ^b   Furuyashiki, Tomoyuki ^a,d   Narumiya, Shuh ^a,d   Urade, Yoshihiro ^b   Ohinata, Kousaku ^a  

^a KYOTO UNIVERSITY   (Japan)

^b OSAKA BIOSCIENCE INSTITUTE   (Japan)

^c RESEARCH INSTITUTE FOR PRODUCTION DEVELOPMENT   (Japan)

^d JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

Opioid; L PGDS; NPY; Orexigenic effect; Peptide

Indexed keywords

CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; DELTA OPIATE RECEPTOR; ISOMERASE; LIPOCALIN; MEMBRANE PROTEIN; NEUROPEPTIDE Y; PEPTIDE FRAGMENT; PROSTAGLANDIN R2 D ISOMERASE; PROSTAGLANDIN R2 D-ISOMERASE; PTGS1 PROTEIN, MOUSE; PTGS2 PROTEIN, MOUSE; RIBULOSEBISPHOSPHATE CARBOXYLASE; RUBISCOLIN 6;

ANIMAL; ARTICLE; C57BL MOUSE; DRUG EFFECT; DRUG POTENTIATION; EATING; GENETICS; MALE; METABOLISM; MOUSE; ORAL DRUG ADMINISTRATION;

ADMINISTRATION, ORAL; ANIMALS; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; EATING; INTRAMOLECULAR OXIDOREDUCTASES; LIPOCALINS; MALE; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; NEUROPEPTIDE Y; PEPTIDE FRAGMENTS; RECEPTORS, OPIOID, DELTA; RIBULOSE-BISPHOSPHATE CARBOXYLASE;

EID: 84865134397     PISSN: 16134125     EISSN: 16134133     Source Type: Journal    
DOI: 10.1002/mnfr.201200155     Document Type: Article

References (52)

1. Morley, J. E., Anorexia of aging: physiologic and pathologic. Am. J. Clin. Nutr. 1997, 66, 760-773.
2. Elmquist, J. K., Hypothalamic pathways underlying the endocrine, autonomic, and behavioral effects of leptin. Int. J. Obes. Relat. Metab. Disord. 2001, 25, S78-82.
3. Inui, A., Asakawa, A., Bowers, C. Y., Mantovani, G. et al., Ghrelin, appetite, and gastric motility: the emerging role of the stomach as an endocrine organ. FASEB J. 2004, 18, 439-456.
4. Gosnell, B. A., Levine, A. S., Morley, J. E., The effects of aging on opioid modulation of feeding in rats. Life Sci. 1983, 32, 2793-2799.
5. Brantl, V., Teschemacher, H., Henschen, A., Lottspeich, F., Novel opioid peptides derived from casein (β-casomorphins). Isolation from bovine casein peptone. Hoppe. Seylers. Z. Physiol. Chem. 1979, 360, 1211-1216.
6. Yoshikawa, M., Yoshimatsu, T., Chiba, H., Opioid peptides from human β-casein. Agric. Biol. Chem. 1984, 48, 3185-3187.
7. Fukudome, S., Yoshikawa, M., Opioid peptides derived from wheat gluten: their isolation and characterization. FEBS Lett. 1992, 296, 107-111.
8. Yang, S., Yunden, J., Sonoda, S., Doyama, N. et al., Rubiscolin, a δ selective opioid peptide derived from plant Rubisco. FEBS Lett. 2001, 509, 213-217.
9. Yang, S., Kawamura, Y., Yoshikawa, M., Effect of rubiscolin, a δ opioid peptide derived from Rubisco, on memory consolidation. Peptides 2003, 24, 325-328.
10. 1 receptors. Peptides 2007, 28, 1998-2003.
11. Ohinata, K., Agui, S., Yoshikawa, M., Soymorphins, novel μ opioid peptides derived from soy β-conglycinin β-subunit, have anxiolytic activities. Biosci. Biotechnol. Biochem. 2007, 71, 2618-2621.
12. B systems. Am. J. Physiol. Gastrointest. Liver Physiol. 2010, 299, 799-805.
13. Ellis, R. J., The most abundant protein in the world. Trends Biochem. Sci. 1979, 4, 241-244.
14. 2 involved in regulation of physiological sleep. Proc. Natl. Acad. Sci. USA 2006, 103, 17949-17954.
15. 2 in the hypothermia of rats caused by bacterial lipopolysaccharide. Proc. Natl. Acad. Sci. USA 1982, 79, 6093-6097.
16. 2 stimulates food intake via the neuropeptide Y system in mice. FEBS Lett. 2008, 582, 679-684.
17. Beuckmann, C. T., Lazarus, M., Gerashchenko, D., Mizoguchi, A. et al., Cellular localization of lipocalin-type prostaglandin D synthase (beta-trace) in the central nervous system of the adult rat. J. Comp. Neurol. 2000, 428, 62-78.
18. Stanley, B. G., Daniel, D. R., Chin, A. S., Leibowitz, S. F., Paraventricular nucleus injections of peptide YY and neuropeptide Y preferentially enhance carbohydrate injestion. Peptides 1985, 6, 1205-1211.
19. Beck, B., Stricker-Krongrad, A., Burlet, A., Nicolas, J. P. et al., Influence of diet composition on food intake and hypothalamic neuropeptide Y (NPY) in the rat. Neuropeptides 1990, 17, 197-203.
20. Billington, C. J., Briggs, J. E., Harker, S., Grace, M. et al., Neuropeptide Y in hypothalamic paraventricular nucleus: a center coordinating energy metabolism. Am. J. Physiol. 1994, 266, R1765-1770.
21. Wang, J., Akabayashi, A., Dourmashkin, J., Yu, H. J. et al., Neuropeptide Y in relation to carbohydrate intake, corticosterone and dietary obesity. Brain Res. 1998, 802, 75-88.
22. Carpino, L. A., Han, G. Y., The 9-fluorenylmethoxycarbonyl function, a new base-sensitive amino-protecting group. J. Amer. Chem. 1970, 92, 5748-5749.
23. 2 as a mediator of allergic asthma. Science 2000, 287, 2013-2017.
24. Mizoguchi, A., Eguchi, N., Kimura, K., Kiyohara, Y. et al., Dominant localization of prostaglandin D receptors on arachnoid trabecular cells in mouse basal forebrain and their involvement in the regulation of non-rapid eye movement sleep. Proc. Natl. Acad. Sci. USA 2001, 98, 11674-11679.
25. 2 synthase knock-out mice. J. Biol. Chem. 2005, 280, 29946-29955.
26. Tanaka, R., Miwa, Y., Mou, K., Tomikawa, M. et al., Knockout of the l-pgds gene aggravates obesity and atherosclerosis in mice. Biochem. Biophys. Res. Commun. 2009, 378, 851-856.
27. Ohinata, K., Inui, A., Asakawa, A., Wada, K. et al., Albutensin A and complement C3a decrease food intake in mice. Peptides 2002, 23, 127-133.
28. 4 subtype suppresses food intake in mice. Prostaglandins Other Lipid Mediat. 2006, 81, 31-36.
29. Ohinata, K., Suetsugu, K., Fujiwara, Y., Yoshikawa, M., Suppression of food intake by a complement C3a agonist [Trp5]-oryzatensin(5-9). Peptides 2007, 28, 602-606.
30. 4 receptor in mice. FEBS Lett. 2008, 582, 773-777.
31. 2-dependent mechanism in mice. Peptides 2009, 30, 1105-1108.
32. Lee, E. C, Yu, D., Martinez, de. Velasco. J. et al., A highly efficient Escherichia coli-based chromosome engineering system adapted for recombinogenic targeting and subcloning of BAC DNA. Genomics 2001, 73, 56-65.
33. Kanki, H., Suzuki, H., Itohara, S., High-efficiency CAG-FLPe deleter mice in C57BL/6J background. Exp. Anim. 2006, 55, 137-141.
34. Tronche, F., Kellendonk, C., Kretz, O., Gass, P. et al., Disruption of the glucocorticoid receptor gene in the nervous system results in reduced anxiety. Nat. Genet. 1999, 23, 99-103.
35. Schwartz, M. W., Woods, S. C., Porte, D. Jr., Seeley, R. J. et al., Central nervous system control of food intake. Nature 2000, 404, 661-671.
36. Yang, S., Sonoda, S., Chen, L., Yoshikawa, M., Structure-activity relationship of rubiscolin as delta opioid peptides. Peptides 2003, 24, 503-508.
37. Bzdega, T., Chin, H., Kim, H., Jung, H. H. et al., Regional expression and chromosomal localization of the delta opiate receptor gene. Proc. Natl. Acad. Sci. USA 1993, 90, 9305-9309.
38. Mansour, A., Fox, C. A., Akil, H., Watson, S. J., Opioid-receptor mRNA expression in the rat CNS: anatomical and functional implications. Trends Neurosci. 1995, 18, 22-29.
39. Gray, A. C., Coupar, I. M., White, P. J., Comparison of opioid receptor distributions in the rat central nervous system. Life Sci. 2006, 79, 674-685.
40. Kodani, E., Xuan, Y. T., Shinmura, K., Takano, H. et al., δ-opioid receptor-induced late preconditioning is mediated by cyclooxygenase-2 in conscious rabbits. Am. J. Physiol. Heart. Circ. Physiol. 2002, 283, H1943-H1957.
41. Patel, H. H., Hsu, A. K., Gross, G. J., COX-2 and iNOS in opioid-induced delayed cardioprotection in the intact rat. Life Sci. 2004, 75, 129-140.
42. Urade, Y., Kitahama, K., Ohishi, H., Kaneko, T. et al., Dominant expression of mRNA for prostaglandin D synthase in leptomenings, choroid plexus, and oligodendrocytes of the adult rat brain. Proc. Natl. Acad. Sci. USA 1993, 90, 9070-9074.
43. 2 receptors. J. Neurochem. 2008, 104, 1345-1357.
44. Adrian, T. E., Allen, J. M., Bloom, S. R., Ghatei, M. A. et al., Neuropeptide Y distribution in human brain. Nature 1983, 306, 584-586.
45. 2 in rat brain. Proc. Natl. Acad. Sci. USA 1983, 80, 6114-6118.
46. 2α in postmortem human brain. Brain Res. 1985, 342, 110-116.
47. 2α binding sites in monkey brain. Brain Res. 1989, 478, 143-148.
48. 2- and neuropeptide Y-dependent mechanism in mice. Prostaglandins Other Lipid Mediat. 2009, 90, 81-84.
49. 2A receptors in the shell of the nucleus accumbens. J. Neurosci. 2011, 31, 10067-10075.
50. Ohinata, K., Yoshikawa, M., Food intake regulation by central complement system. Adv. Exp. Med. Biol. 2008, 632, 35-46.
51. Lin, L., Chen, J., York, D. A., Bray, G. A., β-casomorphins stimulate and enterostatin inhibits the intake of dietary fat in rats. Peptides 1998, 19, 325-331.
52. 1-7 attenuates the suppression of fat intake by enterostatin. Peptides 2000, 21, 1377-1381.