Orally administered soymorphins, soy-derived opioid peptides, suppress feeding and intestinal transit via gut μ1-receptor coupled to 5-HT1A, D2, and GABAB systems

American Journal of Physiology - Gastrointestinal and Liver Physiology

Volumn 299, Issue 3, 2010, Pages

  Kaneko, Kentaro ^a   Iwasaki, Masashi ^a   Yoshikawa, Masaaki ^b   Ohinata, Kousaku ^a  

^a KYOTO UNIVERSITY   (Japan)

^b OSAKA UNIVERSITY   (Japan)

Author keywords

1 opioid receptor; Anorexigenic activity; Small intestinal motility; Soy conglycinin subunit

Indexed keywords

2 DIPROPYLAMINO 8 HYDROXYTETRALIN; BACLOFEN; BROMOCRIPTINE; N TERT BUTYL 3 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL] 2 PHENYLPROPIONAMIDE; NALOXONAZINE; NALOXONE; OPIATE PEPTIDE; RACLOPRIDE; SACLOFEN; SOYBEAN PROTEIN; SOYMORPHIN; UNCLASSIFIED DRUG; 4 AMINOBUTYRIC ACID B RECEPTOR; DOPAMINE 2 RECEPTOR; MU OPIATE RECEPTOR; SEROTONIN 1A RECEPTOR; VEGETABLE PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG MECHANISM; ENZYME ACTIVATION; FEEDING BEHAVIOR; FOOD INTAKE; GABAERGIC SYSTEM; GASTROINTESTINAL TRANSIT; INTESTINE; INTESTINE MOTILITY; MALE; MOUSE; NEUROTRANSMITTER RELEASE; NONHUMAN; PRIORITY JOURNAL; ANIMAL; BAGG ALBINO MOUSE; DRUG EFFECT; DRUG POTENTIATION; EATING; GASTROINTESTINAL MOTILITY; METABOLISM; ORAL DRUG ADMINISTRATION; PHYSIOLOGY; SMALL INTESTINE;

ADMINISTRATION, ORAL; ANIMALS; EATING; GASTROINTESTINAL MOTILITY; INTESTINE, SMALL; MICE; MICE, INBRED BALB C; PLANT PROTEINS; RECEPTOR, SEROTONIN, 5-HT1A; RECEPTORS, DOPAMINE D2; RECEPTORS, GABA-B; RECEPTORS, OPIOID, MU;

EID: 77956993773     PISSN: 01931857     EISSN: 15221547     Source Type: Journal    
DOI: 10.1152/ajpgi.00081.2010     Document Type: Article

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