-
2
-
-
48549098902
-
The pathogenesis and imaging of the tuberous sclerosis complex
-
18414839 10.1007/s00247-008-0832-y
-
Baskin HJ Jr (2008) The pathogenesis and imaging of the tuberous sclerosis complex. Pediatr Radiol 38:936-952
-
(2008)
Pediatr Radiol
, vol.38
, pp. 936-952
-
-
Baskin, Jr.H.J.1
-
3
-
-
49649118165
-
Tuberous sclerosis
-
1:CAS:528:DC%2BD1cXhtVagu7jN 18722871 10.1016/S0140-6736(08)61279-9
-
Curatolo P, Bombardieri R, Jozwiak S (2008) Tuberous sclerosis. Lancet 372:657-668
-
(2008)
Lancet
, vol.372
, pp. 657-668
-
-
Curatolo, P.1
Bombardieri, R.2
Jozwiak, S.3
-
4
-
-
0032438210
-
Tuberous sclerosis complex consensus conference: Revised clinical diagnostic criteria
-
1:STN:280:DyaK1M%2FpsFylsg%3D%3D 9881533 10.1177/088307389801301206
-
Roach ES, Gomez MR, Northrup H (1998) Tuberous sclerosis complex consensus conference: revised clinical diagnostic criteria. J Child Neurol 13:624-628
-
(1998)
J Child Neurol
, vol.13
, pp. 624-628
-
-
Roach, E.S.1
Gomez, M.R.2
Northrup, H.3
-
5
-
-
0034023746
-
National Institutes of Health consensus conference: Tuberous sclerosis complex
-
1:STN:280:DC%2BD3c3ntlaltA%3D%3D 10815131 10.1001/archneur.57.5.662
-
Hyman MH, Whittemore VH (2000) National Institutes of Health consensus conference: tuberous sclerosis complex. Arch Neurol 57:662-665
-
(2000)
Arch Neurol
, vol.57
, pp. 662-665
-
-
Hyman, M.H.1
Whittemore, V.H.2
-
6
-
-
8844231735
-
Diagnosis of tuberous sclerosis complex
-
15563009
-
Roach ES, Sparagana SP (2004) Diagnosis of tuberous sclerosis complex. J Child Neurol 19:643-649
-
(2004)
J Child Neurol
, vol.19
, pp. 643-649
-
-
Roach, E.S.1
Sparagana, S.P.2
-
7
-
-
33847057994
-
Genotype/phenotype correlation in 325 individuals referred for a diagnosis of tuberous sclerosis complex in the United States
-
1:CAS:528:DC%2BD2sXhslCmt7o%3D 17304050 10.1097/GIM.0b013e31803068c7
-
Au KS, Williams AT, Roach ES et al (2007) Genotype/phenotype correlation in 325 individuals referred for a diagnosis of tuberous sclerosis complex in the United States. Genet Med 9:88-100
-
(2007)
Genet Med
, vol.9
, pp. 88-100
-
-
Au, K.S.1
Williams, A.T.2
Roach, E.S.3
-
8
-
-
77954529084
-
The natural history of epilepsy in tuberous sclerosis complex
-
3065368 20041940 10.1111/j.1528-1167.2009.02474.x
-
Chu-Shore CJ, Major P, Camposano S, Muzykewicz D, Thiele EA (2010) The natural history of epilepsy in tuberous sclerosis complex. Epilepsia 51:1236-1241
-
(2010)
Epilepsia
, vol.51
, pp. 1236-1241
-
-
Chu-Shore, C.J.1
Major, P.2
Camposano, S.3
Muzykewicz, D.4
Thiele, E.A.5
-
9
-
-
0027770784
-
Identification and characterization of the tuberous sclerosis gene on chromosome 16
-
European Chromosome 16 Tuberous Sclerosis Consortium 10.1016/0092- 8674(93)90618-Z
-
European Chromosome 16 Tuberous Sclerosis Consortium (1993) Identification and characterization of the tuberous sclerosis gene on chromosome 16. Cell 75:1305-1315
-
(1993)
Cell
, vol.75
, pp. 1305-1315
-
-
-
10
-
-
0030879277
-
Identification of the tuberous sclerosis gene TSC1 on chromosome 9q34
-
9242607 10.1126/science.277.5327.805
-
van Slegtenhorst M, de Hoogt R, Hermans C et al (1997) Identification of the tuberous sclerosis gene TSC1 on chromosome 9q34. Science 277:805-808
-
(1997)
Science
, vol.277
, pp. 805-808
-
-
Van Slegtenhorst, M.1
De Hoogt, R.2
Hermans, C.3
-
11
-
-
0038141979
-
Rheb is a direct target of the tuberous sclerosis tumour suppressor proteins
-
1:CAS:528:DC%2BD3sXktlWnsrk%3D 12771962 10.1038/ncb999
-
Zhang Y, Gao X, Saucedo LJ, Ru B, Edgar BA, Pan D (2003) Rheb is a direct target of the tuberous sclerosis tumour suppressor proteins. Nat Cell Biol 5:578-581
-
(2003)
Nat Cell Biol
, vol.5
, pp. 578-581
-
-
Zhang, Y.1
Gao, X.2
Saucedo, L.J.3
Ru, B.4
Edgar, B.A.5
Pan, D.6
-
12
-
-
33745924695
-
Roles of glutamate receptors and the mammalian target of rapamycin (mTOR) signaling pathway in activity-dependent dendritic protein synthesis in hippocampal neurons
-
1:CAS:528:DC%2BD28XmsVagur0%3D 16651266 10.1074/jbc.M512524200
-
Gong R, Park CS, Abbassi NR, Tang SJ (2006) Roles of glutamate receptors and the mammalian target of rapamycin (mTOR) signaling pathway in activity-dependent dendritic protein synthesis in hippocampal neurons. J Biol Chem 281:18802-18815
-
(2006)
J Biol Chem
, vol.281
, pp. 18802-18815
-
-
Gong, R.1
Park, C.S.2
Abbassi, N.R.3
Tang, S.J.4
-
13
-
-
33749639034
-
Activity- and mTOR-dependent suppression of Kv1.1 channel mRNA translation in dendrites
-
1:CAS:528:DC%2BD28XhtVCiurvN 17023663 10.1126/science.1131693
-
Raab-Graham KF, Haddick PC, Jan YN, Jan LY (2006) Activity- and mTOR-dependent suppression of Kv1.1 channel mRNA translation in dendrites. Science 314:144-148
-
(2006)
Science
, vol.314
, pp. 144-148
-
-
Raab-Graham, K.F.1
Haddick, P.C.2
Jan, Y.N.3
Jan, L.Y.4
-
14
-
-
28044456974
-
Regulation of neuronal morphology and function by the tumor suppressors Tsc1 and Tsc2
-
1:CAS:528:DC%2BD2MXht1Gis77M 16286931 10.1038/nn1566
-
Tavazoie SF, Alvarez VA, Ridenour DA, Kwiatkowski DJ, Sabatini BL (2005) Regulation of neuronal morphology and function by the tumor suppressors Tsc1 and Tsc2. Nat Neurosci 8:1727-1734
-
(2005)
Nat Neurosci
, vol.8
, pp. 1727-1734
-
-
Tavazoie, S.F.1
Alvarez, V.A.2
Ridenour, D.A.3
Kwiatkowski, D.J.4
Sabatini, B.L.5
-
15
-
-
33645738458
-
Complexity of the TOR signaling network
-
1:CAS:528:DC%2BD28Xjs1Grur4%3D 16516475 10.1016/j.tcb.2006.02.002
-
Inoki K, Guan KL (2006) Complexity of the TOR signaling network. Trends Cell Biol 16:206-212
-
(2006)
Trends Cell Biol
, vol.16
, pp. 206-212
-
-
Inoki, K.1
Guan, K.L.2
-
16
-
-
78650987740
-
Tuberous sclerosis complex: Neurological, renal and pulmonary manifestations
-
1:CAS:528:DC%2BC3MXjsFOhs7g%3D 21210335 10.1055/s-0030-1269906
-
Franz DN, Bissler JJ, McCormack FX (2010) Tuberous sclerosis complex: neurological, renal and pulmonary manifestations. Neuropediatrics 41:199-208
-
(2010)
Neuropediatrics
, vol.41
, pp. 199-208
-
-
Franz, D.N.1
Bissler, J.J.2
McCormack, F.X.3
-
17
-
-
81455151255
-
The tuberous sclerosis complex
-
1:CAS:528:DC%2BD2sXisVGit7c%3D 17005952 10.1056/NEJMra055323
-
Crino PB, Nathanson KL, Henske EP (2006) The tuberous sclerosis complex. N Engl J Med 355:1345-1356
-
(2006)
N Engl J Med
, vol.355
, pp. 1345-1356
-
-
Crino, P.B.1
Nathanson, K.L.2
Henske, E.P.3
-
18
-
-
0016724057
-
Rapamycin (AY-22,989), a new antifungal antibiotic. I. Taxonomy of the producing streptomycete and isolation of the active principle
-
1:CAS:528:DyaE28Xis1eruw%3D%3D 10.7164/antibiotics.28.721
-
Vezina C, Kudelski A, Sehgal SN (1975) Rapamycin (AY-22,989), a new antifungal antibiotic. I. Taxonomy of the producing streptomycete and isolation of the active principle. J Antibiot (Tokyo) 28:721-726
-
(1975)
J Antibiot (Tokyo)
, vol.28
, pp. 721-726
-
-
Vezina, C.1
Kudelski, A.2
Sehgal, S.N.3
-
19
-
-
33947193386
-
Use of sirolimus in solid organ transplantation
-
1:CAS:528:DC%2BD2sXkvFehsb4%3D 17335296 10.2165/00003495-200767030-00004
-
Augustine JJ, Bodziak KA, Hricik DE (2007) Use of sirolimus in solid organ transplantation. Drugs 67:369-391
-
(2007)
Drugs
, vol.67
, pp. 369-391
-
-
Augustine, J.J.1
Bodziak, K.A.2
Hricik, D.E.3
-
20
-
-
33846236407
-
Dramatic effect of sirolimus on renal angiomyolipomas in a patient with tuberous sclerosis complex
-
17223050 10.1016/j.ejim.2006.07.017
-
Herry I, Neukirch C, Debray MP, Mignon F, Crestani B (2007) Dramatic effect of sirolimus on renal angiomyolipomas in a patient with tuberous sclerosis complex. Eur J Intern Med 18:76-77
-
(2007)
Eur J Intern Med
, vol.18
, pp. 76-77
-
-
Herry, I.1
Neukirch, C.2
Debray, M.P.3
Mignon, F.4
Crestani, B.5
-
21
-
-
33644827461
-
Rapamycin causes regression of astrocytomas in tuberous sclerosis complex
-
1:CAS:528:DC%2BD28XjtV2ltr8%3D 16453317 10.1002/ana.20784
-
Franz DN, Leonard J, Tudor C et al (2006) Rapamycin causes regression of astrocytomas in tuberous sclerosis complex. Ann Neurol 59:490-498
-
(2006)
Ann Neurol
, vol.59
, pp. 490-498
-
-
Franz, D.N.1
Leonard, J.2
Tudor, C.3
-
22
-
-
47549093135
-
The mTOR inhibitor rapamycin significantly improves facial angiofibroma lesions in a patient with tuberous sclerosis
-
1:CAS:528:DC%2BD1cXhtVCqs7bO 18547304 10.1111/j.1365-2133.2008.08677.x
-
Hofbauer GF, Marcollo-Pini A, Corsenca A et al (2008) The mTOR inhibitor rapamycin significantly improves facial angiofibroma lesions in a patient with tuberous sclerosis. Br J Dermatol 159:473-475
-
(2008)
Br J Dermatol
, vol.159
, pp. 473-475
-
-
Hofbauer, G.F.1
Marcollo-Pini, A.2
Corsenca, A.3
-
23
-
-
77958178123
-
Rapamycin therapy for renal, brain, and skin lesions in a tuberous sclerosis patient
-
20954988 10.3109/0886022X.2010.517345
-
Micozkadioglu H, Koc Z, Ozelsancak R, Yildiz I (2010) Rapamycin therapy for renal, brain, and skin lesions in a tuberous sclerosis patient. Ren Fail 32:1233-1236
-
(2010)
Ren Fail
, vol.32
, pp. 1233-1236
-
-
Micozkadioglu, H.1
Koc, Z.2
Ozelsancak, R.3
Yildiz, I.4
-
24
-
-
66149169973
-
The mammalian target of rapamycin signaling pathway mediates epileptogenesis in a model of temporal lobe epilepsy
-
1:CAS:528:DC%2BD1MXmvVGisL0%3D 2727061 19474323 10.1523/JNEUROSCI.0066- 09.2009
-
Zeng LH, Rensing NR, Wong M (2009) The mammalian target of rapamycin signaling pathway mediates epileptogenesis in a model of temporal lobe epilepsy. J Neurosci 29:6964-6972
-
(2009)
J Neurosci
, vol.29
, pp. 6964-6972
-
-
Zeng, L.H.1
Rensing, N.R.2
Wong, M.3
-
25
-
-
42949140259
-
Rapamycin prevents epilepsy in a Mouse model of tuberous sclerosis complex
-
1:CAS:528:DC%2BD1cXmsFGqt7c%3D 18389497 10.1002/ana.21331
-
Zeng LH, Xu L, Gutmann DH, Wong M (2008) Rapamycin prevents epilepsy in a Mouse model of tuberous sclerosis complex. Ann Neurol 63:444-453
-
(2008)
Ann Neurol
, vol.63
, pp. 444-453
-
-
Zeng, L.H.1
Xu, L.2
Gutmann, D.H.3
Wong, M.4
-
26
-
-
64249118425
-
Rapamycin reduces seizure frequency in tuberous sclerosis complex
-
3072696 19151365 10.1177/0883073808324535
-
Muncy J, Butler IJ, Koenig MK (2009) Rapamycin reduces seizure frequency in tuberous sclerosis complex. J Child Neurol 24:477
-
(2009)
J Child Neurol
, vol.24
, pp. 477
-
-
Muncy, J.1
Butler, I.J.2
Koenig, M.K.3
-
27
-
-
84855163851
-
Surgical timing of the subependymal giant cell astrocytoma (SEGA) with the patients of tuberous sclerosis complex
-
21845566
-
Ekici MA, Kumandas S, Per H et al (2011) Surgical timing of the subependymal giant cell astrocytoma (SEGA) with the patients of tuberous sclerosis complex. Turk Neurosurg 21:315-324
-
(2011)
Turk Neurosurg
, vol.21
, pp. 315-324
-
-
Ekici, M.A.1
Kumandas, S.2
Per, H.3
-
28
-
-
0036263937
-
Neuro-epileptic determinants of autism spectrum disorders in tuberous sclerosis complex
-
12023313 10.1093/brain/awf124
-
Bolton PF, Park RJ, Higgins JN, Griffiths PD, Pickles A (2002) Neuro-epileptic determinants of autism spectrum disorders in tuberous sclerosis complex. Brain 125:1247-1255
-
(2002)
Brain
, vol.125
, pp. 1247-1255
-
-
Bolton, P.F.1
Park, R.J.2
Higgins, J.N.3
Griffiths, P.D.4
Pickles, A.5
-
29
-
-
12244298162
-
Learning disability and epilepsy in an epidemiological sample of individuals with tuberous sclerosis complex
-
1:STN:280:DC%2BD3s7gvFeruw%3D%3D 12622312 10.1017/S0033291702007092
-
Joinson C, O'Callaghan FJ, Osborne JP, Martyn C, Harris T, Bolton PF (2003) Learning disability and epilepsy in an epidemiological sample of individuals with tuberous sclerosis complex. Psychol Med 33:335-344
-
(2003)
Psychol Med
, vol.33
, pp. 335-344
-
-
Joinson, C.1
O'Callaghan, F.J.2
Osborne, J.P.3
Martyn, C.4
Harris, T.5
Bolton, P.F.6
-
30
-
-
0031897224
-
Poor mental development in patients with tuberous sclerosis complex: Clinical risk factors
-
1:STN:280:DyaK1c7nvVygtg%3D%3D 9520012 10.1001/archneur.55.3.379
-
Jozwiak S, Goodman M, Lamm SH (1998) Poor mental development in patients with tuberous sclerosis complex: clinical risk factors. Arch Neurol 55:379-384
-
(1998)
Arch Neurol
, vol.55
, pp. 379-384
-
-
Jozwiak, S.1
Goodman, M.2
Lamm, S.H.3
-
31
-
-
22544488406
-
Infantile spasms and intellectual outcomes in children with tuberous sclerosis complex
-
16043792 10.1212/01.wnl.0000168908.78118.99
-
Goh S, Kwiatkowski DJ, Dorer DJ, Thiele EA (2005) Infantile spasms and intellectual outcomes in children with tuberous sclerosis complex. Neurology 65:235-238
-
(2005)
Neurology
, vol.65
, pp. 235-238
-
-
Goh, S.1
Kwiatkowski, D.J.2
Dorer, D.J.3
Thiele, E.A.4
-
32
-
-
0033991818
-
Mental and behavioural outcome of infantile epilepsy treated by vigabatrin in tuberous sclerosis patients
-
1:CAS:528:DyaK1MXnvFensbg%3D 10642043 10.1016/S0920-1211(99)00082-0
-
Jambaque I, Chiron C, Dumas C, Mumford J, Dulac O (2000) Mental and behavioural outcome of infantile epilepsy treated by vigabatrin in tuberous sclerosis patients. Epilepsy Res 38:151-160
-
(2000)
Epilepsy Res
, vol.38
, pp. 151-160
-
-
Jambaque, I.1
Chiron, C.2
Dumas, C.3
Mumford, J.4
Dulac, O.5
-
33
-
-
39749141046
-
Neuroimaging correlation with neurological severity in tuberous sclerosis complex
-
17869556 10.1016/j.ejpn.2007.07.002
-
Chou IJ, Lin KL, Wong AM et al (2008) Neuroimaging correlation with neurological severity in tuberous sclerosis complex. Eur J Paediatr Neurol 12:108-112
-
(2008)
Eur J Paediatr Neurol
, vol.12
, pp. 108-112
-
-
Chou, I.J.1
Lin, K.L.2
Wong, A.M.3
-
34
-
-
0032052110
-
CT and MR imaging of cerebral tuberous sclerosis
-
10.1016/S0387-7604(98)00022-9
-
Inoue Y, Nemoto Y, Murata R et al (1988) CT and MR imaging of cerebral tuberous sclerosis. Brain Dev 20:209-221
-
(1988)
Brain Dev
, vol.20
, pp. 209-221
-
-
Inoue, Y.1
Nemoto, Y.2
Murata, R.3
-
35
-
-
33947098824
-
Neuroimaging in tuberous sclerosis complex
-
1:CAS:528:DC%2BD2sXkvFegtr4%3D 17351483 10.1097/WCO.0b013e3280895d93
-
Luat AF, Makki M, Chugani HT (2007) Neuroimaging in tuberous sclerosis complex. Curr Opin Neurol 20:142-150
-
(2007)
Curr Opin Neurol
, vol.20
, pp. 142-150
-
-
Luat, A.F.1
Makki, M.2
Chugani, H.T.3
-
36
-
-
84878502738
-
Subependymal nodules and giant cell tumours in tuberous sclerosis complex patients: Prevalence on MRI in relation to gene mutation
-
22936080 10.1007/s00381-012-1892-8
-
Michelozzi C, Di Leo G, Galli F et al (2013) Subependymal nodules and giant cell tumours in tuberous sclerosis complex patients: prevalence on MRI in relation to gene mutation. Childs Nerv Syst 29:249-254
-
(2013)
Childs Nerv Syst
, vol.29
, pp. 249-254
-
-
Michelozzi, C.1
Di Leo, G.2
Galli, F.3
-
37
-
-
0032941743
-
Early diagnosis of subependymal giant cell astrocytoma in children with tuberous sclerosis
-
1:STN:280:DyaK1M7ot1Shug%3D%3D 10084537 10.1136/jnnp.66.3.370
-
Nabbout R, Santos M, Rolland Y, Delalande O, Dulac O, Chiron C (1999) Early diagnosis of subependymal giant cell astrocytoma in children with tuberous sclerosis. J Neurol Neurosurg Psychiatry 66:370-375
-
(1999)
J Neurol Neurosurg Psychiatry
, vol.66
, pp. 370-375
-
-
Nabbout, R.1
Santos, M.2
Rolland, Y.3
Delalande, O.4
Dulac, O.5
Chiron, C.6
-
38
-
-
36249023723
-
Effects of rapamycin on gene expression, morphology, and electrophysiological properties of rat hippocampal neurons
-
3474316 17983731 10.1016/j.eplepsyres.2007.09.009
-
Rüegg S, Baybis M, Juul H, Dichter M, Crino PB (2007) Effects of rapamycin on gene expression, morphology, and electrophysiological properties of rat hippocampal neurons. Epilepsy Res 77:85-92
-
(2007)
Epilepsy Res
, vol.77
, pp. 85-92
-
-
Rüegg, S.1
Baybis, M.2
Juul, H.3
Dichter, M.4
Crino, P.B.5
-
39
-
-
0037741092
-
Subependymal giant cell astrocytoma in children with tuberous sclerosis
-
12715190
-
Cuccia V, Zuccaro G, Sosa F, Monges J, Lubienieky F, Taratuto AL (2003) Subependymal giant cell astrocytoma in children with tuberous sclerosis. Childs Nerv Syst 19:232-243
-
(2003)
Childs Nerv Syst
, vol.19
, pp. 232-243
-
-
Cuccia, V.1
Zuccaro, G.2
Sosa, F.3
Monges, J.4
Lubienieky, F.5
Taratuto, A.L.6
-
40
-
-
38049169559
-
Sirolimus for angiomyolipoma in tuberous sclerosis complex or lymphangioleiomyomatosis
-
1:CAS:528:DC%2BD1cXltFWrtg%3D%3D 3398441 18184959 10.1056/NEJMoa063564
-
Bissler JJ, McCormack FX, Young LR et al (2008) Sirolimus for angiomyolipoma in tuberous sclerosis complex or lymphangioleiomyomatosis. N Engl J Med 358:140-151
-
(2008)
N Engl J Med
, vol.358
, pp. 140-151
-
-
Bissler, J.J.1
McCormack, F.X.2
Young, L.R.3
-
41
-
-
79551594354
-
Fetal and neonatal cardiac rhabdomyomas: Clinical presentation, outcome and association with tuberous sclerosis complex
-
21434532
-
Atalay S, Aypar E, Uçar T et al (2010) Fetal and neonatal cardiac rhabdomyomas: clinical presentation, outcome and association with tuberous sclerosis complex. Turk J Pediatr 52:481-487
-
(2010)
Turk J Pediatr
, vol.52
, pp. 481-487
-
-
Atalay, S.1
Aypar, E.2
Uçar, T.3
-
42
-
-
8844285191
-
Managing epilepsy in tuberous sclerosis complex
-
15563014
-
Thiele E (2004) Managing epilepsy in tuberous sclerosis complex. J Child Neurol 19:680-686
-
(2004)
J Child Neurol
, vol.19
, pp. 680-686
-
-
Thiele, E.1
-
43
-
-
33845927451
-
Gradual formation of an operative corridor by balloon dilation for resection of subependymal giant cell astrocytomas in children with tuberous sclerosis: Specialized minimal access technique of balloon dilation
-
1:STN:280:DC%2BD28jis1GitQ%3D%3D 17163349 10.1055/s-2006-950391
-
Levine NB, Collins J, Franz DN, Crone KR (2006) Gradual formation of an operative corridor by balloon dilation for resection of subependymal giant cell astrocytomas in children with tuberous sclerosis: specialized minimal access technique of balloon dilation. Minim Invasive Neurosurg 49:317-320
-
(2006)
Minim Invasive Neurosurg
, vol.49
, pp. 317-320
-
-
Levine, N.B.1
Collins, J.2
Franz, D.N.3
Crone, K.R.4
-
45
-
-
0032721611
-
Visual field defects associated with vigabatrin therapy
-
1:STN:280:DC%2BD3c%2Fjs1OitQ%3D%3D 10567485 10.1136/jnnp.67.6.716
-
Lawden MC, Eke T, Degg C, Harding GF, Wild JM (1999) Visual field defects associated with vigabatrin therapy. J Neurol Neurosurg Psychiatry 67:716-722
-
(1999)
J Neurol Neurosurg Psychiatry
, vol.67
, pp. 716-722
-
-
Lawden, M.C.1
Eke, T.2
Degg, C.3
Harding, G.F.4
Wild, J.M.5
-
46
-
-
3042825407
-
Combined treatment with vigabatrin and topiramate in West syndrome
-
15224711 10.1177/088307380401900512
-
Buoni S, Zannolli R, Strambi M, Fois A (2004) Combined treatment with vigabatrin and topiramate in West syndrome. J Child Neurol 19:385-386
-
(2004)
J Child Neurol
, vol.19
, pp. 385-386
-
-
Buoni, S.1
Zannolli, R.2
Strambi, M.3
Fois, A.4
-
47
-
-
79958184395
-
A pulse rapamycin therapy for infantile spasms and associated cognitive decline
-
1:CAS:528:DC%2BC3MXnsFWhtbY%3D 3114281 21504792 10.1016/j.nbd.2011.03.021
-
Raffo E, Coppola A, Ono T, Briggs SW, Galanopoulou AS (2011) A pulse rapamycin therapy for infantile spasms and associated cognitive decline. Neurobiol Dis 43:322-329
-
(2011)
Neurobiol Dis
, vol.43
, pp. 322-329
-
-
Raffo, E.1
Coppola, A.2
Ono, T.3
Briggs, S.W.4
Galanopoulou, A.S.5
-
48
-
-
27244460363
-
Tuberous sclerosis complex and the ketogenic diet
-
16190943 10.1111/j.1528-1167.2005.00266.x
-
Kossoff EH, Thiele EA, Pfeifer HH, McGrogan JR, Freeman JM (2005) Tuberous sclerosis complex and the ketogenic diet. Epilepsia 46:1684-1686
-
(2005)
Epilepsia
, vol.46
, pp. 1684-1686
-
-
Kossoff, E.H.1
Thiele, E.A.2
Pfeifer, H.H.3
McGrogan, J.R.4
Freeman, J.M.5
-
49
-
-
84858006041
-
Rapamycin for treatment of epilepsy: Antiseizure, antiepileptogenic, both, or neither?
-
3117496 21852879 10.5698/1535-7511-11.2.66
-
Wong M (2011) Rapamycin for treatment of epilepsy: antiseizure, antiepileptogenic, both, or neither? Epilepsy Curr 11:66-68
-
(2011)
Epilepsy Curr
, vol.11
, pp. 66-68
-
-
Wong, M.1
-
50
-
-
67649382228
-
Inhibition of the mammalian target of rapamycin signaling pathway suppresses dentate granule cell axon sprouting in a rodent model of temporal lobe epilepsy
-
1:CAS:528:DC%2BD1MXotFKgu74%3D 2819377 19553465 10.1523/JNEUROSCI.4179- 08.2009
-
Buckmaster PS, Ingram EA, Wen X (2009) Inhibition of the mammalian target of rapamycin signaling pathway suppresses dentate granule cell axon sprouting in a rodent model of temporal lobe epilepsy. J Neurosci 29:8259-8269
-
(2009)
J Neurosci
, vol.29
, pp. 8259-8269
-
-
Buckmaster, P.S.1
Ingram, E.A.2
Wen, X.3
-
51
-
-
84856372774
-
Post-treatment with rapamycin does not prevent epileptogenesis in the amygdala stimulation model of temporal lobe epilepsy
-
1:CAS:528:DC%2BC38XhvVGgtro%3D 22227620 10.1016/j.neulet.2011.12.051
-
Sliwa A, Plucinska G, Bednarczyk J, Lukasiuk K (2012) Post-treatment with rapamycin does not prevent epileptogenesis in the amygdala stimulation model of temporal lobe epilepsy. Neurosci Lett 509:105-109
-
(2012)
Neurosci Lett
, vol.509
, pp. 105-109
-
-
Sliwa, A.1
Plucinska, G.2
Bednarczyk, J.3
Lukasiuk, K.4
-
52
-
-
84857648355
-
American Epilepsy Society Basic Science Committee and the International League Against Epilepsy Working Group on Recommendations for Preclinical Epilepsy Drug Discovery. Identification of new epilepsy treatments: Issues in preclinical methodology
-
3551973 22292566 10.1111/j.1528-1167.2011.03391.x
-
Galanopoulou AS, Buckmaster PS, Staley KJ et al (2012) American Epilepsy Society Basic Science Committee and The International League Against Epilepsy Working Group on Recommendations for Preclinical Epilepsy Drug Discovery. Identification of new epilepsy treatments: issues in preclinical methodology. Epilepsia 53:571-582
-
(2012)
Epilepsia
, vol.53
, pp. 571-582
-
-
Galanopoulou, A.S.1
Buckmaster, P.S.2
Staley, K.J.3
-
53
-
-
68349100270
-
Rapamycin suppresses seizures and neuronal hypertrophy in a mouse model of cortical dysplasia
-
1:CAS:528:DC%2BD1MXhtVahs7bO 2707106 19470613 10.1242/dmm.002386
-
Ljungberg MC, Sunnen CN, Lugo JN, Anderson AE, D'Arcangelo G (2009) Rapamycin suppresses seizures and neuronal hypertrophy in a mouse model of cortical dysplasia. Dis Model Mech 2:389-398
-
(2009)
Dis Model Mech
, vol.2
, pp. 389-398
-
-
Ljungberg, M.C.1
Sunnen, C.N.2
Lugo, J.N.3
Anderson, A.E.4
D'Arcangelo, G.5
-
54
-
-
60849109211
-
Pharmacological inhibition of mTORC1 suppresses anatomical, cellular, and behavioral abnormalities in neural-specific Pten knock-out mice
-
1:CAS:528:DC%2BD1MXit1Witbo%3D 3904448 19211884 10.1523/JNEUROSCI.5685- 08.2009
-
Zhou J, Blundell J, Ogawa S et al (2009) Pharmacological inhibition of mTORC1 suppresses anatomical, cellular, and behavioral abnormalities in neural-specific Pten knock-out mice. J Neurosci 29:1773-1783
-
(2009)
J Neurosci
, vol.29
, pp. 1773-1783
-
-
Zhou, J.1
Blundell, J.2
Ogawa, S.3
-
55
-
-
77955845741
-
Pharmacological inhibition of the mammalian target of rapamycin pathway suppresses acquired epilepsy
-
1:CAS:528:DC%2BC3cXhtVGrt7zP 2926303 20566381 10.1016/j.nbd.2010.05.024
-
Huang X, Zhang H, Yang J et al (2010) Pharmacological inhibition of the mammalian target of rapamycin pathway suppresses acquired epilepsy. Neurobiol Dis 40:193-199
-
(2010)
Neurobiol Dis
, vol.40
, pp. 193-199
-
-
Huang, X.1
Zhang, H.2
Yang, J.3
-
56
-
-
84863727156
-
Finding a better drug for epilepsy: The mTOR pathway as an antiepileptogenic target
-
1:CAS:528:DC%2BC38Xht1KksbzF 3389589 22578218 10.1111/j.1528-1167.2012. 03506.x
-
Galanopoulou AS, Gorter JA, Cepeda C (2012) Finding a better drug for epilepsy: the mTOR pathway as an antiepileptogenic target. Epilepsia 53:1119-1130
-
(2012)
Epilepsia
, vol.53
, pp. 1119-1130
-
-
Galanopoulou, A.S.1
Gorter, J.A.2
Cepeda, C.3
-
57
-
-
0032498882
-
+ channel is modulated by FK506 and rapamycin
-
1:CAS:528:DyaK1cXitlSlt7Y%3D 9555045 10.1016/S0006-8993(97)01435-2
-
+ channel is modulated by FK506 and rapamycin. Brain Res 786:255-258
-
(1998)
Brain Res
, vol.786
, pp. 255-258
-
-
Terashima, A.1
Nakai, M.2
Hashimoto, T.3
-
58
-
-
33646391271
-
A role for the mTOR pathway in surface expression of AMPA receptors
-
1:CAS:528:DC%2BD28Xks1Oltbg%3D 16677760 10.1016/j.neulet.2006.03.011
-
Wang Y, Barbaro MF, Baraban SC (2006) A role for the mTOR pathway in surface expression of AMPA receptors. Neurosci Lett 401:35-39
-
(2006)
Neurosci Lett
, vol.401
, pp. 35-39
-
-
Wang, Y.1
Barbaro, M.F.2
Baraban, S.C.3
-
59
-
-
38349090475
-
Binding of rapamycin analogs to calcium channels and FKBP52 contributes to their neuroprotective activities
-
1:CAS:528:DC%2BD1cXpvV2ksg%3D%3D 18162540 10.1073/pnas.0710424105
-
Ruan B, Pong K, Jow F et al (2008) Binding of rapamycin analogs to calcium channels and FKBP52 contributes to their neuroprotective activities. Proc Natl Acad Sci USA 105:33-38
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 33-38
-
-
Ruan, B.1
Pong, K.2
Jow, F.3
-
60
-
-
34247111348
-
Rapamycin: Brain excitability studied in vitro
-
1:CAS:528:DC%2BD2sXlsVWgtrs%3D 17284292 10.1111/j.1528-1167.2006.00976.x
-
Daoud D, Scheld HH, Speckmann EJ, Gorji A (2007) Rapamycin: brain excitability studied in vitro. Epilepsia 48:834-836
-
(2007)
Epilepsia
, vol.48
, pp. 834-836
-
-
Daoud, D.1
Scheld, H.H.2
Speckmann, E.J.3
Gorji, A.4
-
61
-
-
81955160719
-
Enhanced GABAergic network and receptor function in pediatric cortical dysplasia Type IIB compared with Tuberous Sclerosis Complex
-
1:CAS:528:DC%2BC3MXhsFGqsLnO 3225687 21889982 10.1016/j.nbd.2011.08.015
-
Cepeda C, Andre VM, Hauptman JS et al (2012) Enhanced GABAergic network and receptor function in pediatric cortical dysplasia Type IIB compared with Tuberous Sclerosis Complex. Neurobiol Dis 45:310-321
-
(2012)
Neurobiol Dis
, vol.45
, pp. 310-321
-
-
Cepeda, C.1
Andre, V.M.2
Hauptman, J.S.3
-
62
-
-
76249084241
-
Mammalian target of rapamycin (mTOR) inhibition as a potential antiepileptogenic therapy: From tuberous sclerosis to common acquired epilepsies
-
1:CAS:528:DC%2BC3cXhsFCms7s%3D 3022513 19817806 10.1111/j.1528-1167.2009. 02341.x
-
Wong M (2010) Mammalian target of rapamycin (mTOR) inhibition as a potential antiepileptogenic therapy: from tuberous sclerosis to common acquired epilepsies. Epilepsia 51:27-36
-
(2010)
Epilepsia
, vol.51
, pp. 27-36
-
-
Wong, M.1
-
63
-
-
84877589482
-
Mammalian target of rapamycin (mTOR) activation in focal cortical dysplasia and related focal cortical malformations
-
Wong M (2011) Mammalian target of rapamycin (mTOR) activation in focal cortical dysplasia and related focal cortical malformations. Exp Neurol 244:22-26
-
(2011)
Exp Neurol
, vol.244
, pp. 22-26
-
-
Wong, M.1
-
64
-
-
78049510428
-
Everolimus for subependymal giant-cell astrocytomas in tuberous sclerosis
-
1:CAS:528:DC%2BC3cXhtl2gsbbP 21047224 10.1056/NEJMoa1001671
-
Krueger DA, Care MM, Holland K et al (2010) Everolimus for subependymal giant-cell astrocytomas in tuberous sclerosis. N Engl J Med 363:1801-1811
-
(2010)
N Engl J Med
, vol.363
, pp. 1801-1811
-
-
Krueger, D.A.1
Care, M.M.2
Holland, K.3
-
65
-
-
33745481867
-
The diverse clinical manifestations of tuberous sclerosis complex: A review
-
16818173 10.1016/j.spen.2006.01.008
-
Rosser T, Panigrahy A, McClintock W (2006) The diverse clinical manifestations of tuberous sclerosis complex: a review. Semin Pediatr Neurol 13:27-36
-
(2006)
Semin Pediatr Neurol
, vol.13
, pp. 27-36
-
-
Rosser, T.1
Panigrahy, A.2
McClintock, W.3
-
66
-
-
8844240684
-
Behavioral and cognitive aspects of tuberous sclerosis complex
-
15563012
-
Prather P, de Vries PJ (2004) Behavioral and cognitive aspects of tuberous sclerosis complex. J Child Neurol 19:666-674
-
(2004)
J Child Neurol
, vol.19
, pp. 666-674
-
-
Prather, P.1
De Vries, P.J.2
-
67
-
-
0014978690
-
Renal angiomyolipoma (hamartoma): Review of the literature and report of 7 cases
-
1:STN:280:DyaE3M7gvVyhuw%3D%3D 5100869
-
McCullough DL, Scott R Jr, Seybold HM (1971) Renal angiomyolipoma (hamartoma): review of the literature and report of 7 cases. J Urol 105:32-44
-
(1971)
J Urol
, vol.105
, pp. 32-44
-
-
McCullough, D.L.1
Scott, Jr.R.2
Seybold, H.M.3
-
68
-
-
0023270237
-
Renal lesions in tuberous sclerosis
-
1:STN:280:DyaL2szhtF2juw%3D%3D 3625844
-
Stillwell TJ, Gomez MR, Kelalis PP (1987) Renal lesions in tuberous sclerosis. J Urol 138:477-481
-
(1987)
J Urol
, vol.138
, pp. 477-481
-
-
Stillwell, T.J.1
Gomez, M.R.2
Kelalis, P.P.3
-
69
-
-
0027758317
-
The natural history of renal angiomyolipoma
-
1:STN:280:DyaK2c%2FkslCjug%3D%3D 8230504
-
Steiner MS, Goldman SM, Fishman EK, Marshall FF (1993) The natural history of renal angiomyolipoma. J Urol 150:1782-1786
-
(1993)
J Urol
, vol.150
, pp. 1782-1786
-
-
Steiner, M.S.1
Goldman, S.M.2
Fishman, E.K.3
Marshall, F.F.4
-
70
-
-
0036830140
-
Tuberous sclerosis complex: Renal imaging findings
-
12409579 10.1148/radiol.2252011584
-
Casper KA, Donnelly LF, Chen B, Bissler JJ (2002) Tuberous sclerosis complex: renal imaging findings. Radiology 225:451-456
-
(2002)
Radiology
, vol.225
, pp. 451-456
-
-
Casper, K.A.1
Donnelly, L.F.2
Chen, B.3
Bissler, J.J.4
-
71
-
-
79958284085
-
Effects of rapamycin on angiomyolipomas in patients with tuberous sclerosis
-
21629335
-
Cabrera Lopez C, Marti T, Catala V et al (2011) Effects of rapamycin on angiomyolipomas in patients with tuberous sclerosis. Nefrologia 31:292-298
-
(2011)
Nefrologia
, vol.31
, pp. 292-298
-
-
Cabrera Lopez, C.1
Marti, T.2
Catala, V.3
-
72
-
-
84856546231
-
Facial angiofibromas treated with topical rapamycin: An excellent choice with fast response
-
22301052
-
Truchuelo T, Díaz-Ley B, Ríos L, Alcántara J, Jaén P (2012) Facial angiofibromas treated with topical rapamycin: an excellent choice with fast response. Dermatol Online J 18:15
-
(2012)
Dermatol Online J
, vol.18
, pp. 15
-
-
Truchuelo, T.1
Díaz-Ley, B.2
Ríos, L.3
Alcántara, J.4
Jaén, P.5
-
73
-
-
41449112167
-
Topical rapamycin inhibits tuberous sclerosis tumor growth in a nude mouse model
-
2266897 18226258 10.1186/1471-5945-8-1
-
Rauktys A, Lee N, Lee L, Dabora SL (2008) Topical rapamycin inhibits tuberous sclerosis tumor growth in a nude mouse model. BMC Dermatol 8:1
-
(2008)
BMC Dermatol
, vol.8
, pp. 1
-
-
Rauktys, A.1
Lee, N.2
Lee, L.3
Dabora, S.L.4
|