Rapamycin reduces seizure frequency in tuberous sclerosis complex

Journal of Child Neurology

Volumn 24, Issue 4, 2009, Pages 477-

  Muncy, Jennifer ^b   Butler, Ian J ^a   Koenig, Kay Mary ^a  

^a UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF TEXAS   (United States)

Author keywords

Rapamycin; Seizures; Tuberous sclerosis

Indexed keywords

CARBAMAZEPINE; ETIRACETAM; GABAPENTIN; LAMOTRIGINE; OXCARBAZEPINE; PHENOBARBITAL; RAPAMYCIN; TIAGABINE; TOPIRAMATE; VALPROIC ACID;

ARTICLE; CASE REPORT; CHILD; DISEASE COURSE; DRUG DOSE INCREASE; DRUG DOSE REDUCTION; DRUG DOSE TITRATION; DRUG EFFICACY; DRUG MECHANISM; FEMALE; HUMAN; OUTCOME ASSESSMENT; PRIORITY JOURNAL; SCHOOL CHILD; SEIZURE; TREATMENT DURATION; TUBEROUS SCLEROSIS;

ANTICONVULSANTS; CARBAMAZEPINE; CEREBRAL CORTEX; CHILD; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG THERAPY, COMBINATION; FEMALE; FRUCTOSE; HUMANS; IMMUNOSUPPRESSIVE AGENTS; MAGNETIC RESONANCE IMAGING; NEUROSURGICAL PROCEDURES; PARESIS; SEIZURES; SIROLIMUS; TREATMENT OUTCOME; TUBEROUS SCLEROSIS; VIRUS DISEASES;

EID: 64249118425     PISSN: 08830738     EISSN: None     Source Type: Journal    
DOI: 10.1177/0883073808324535     Document Type: Article

References (1)

1. Zeng LH, Xu L., Gutmann DH, Wong M. Rapamycin prevents epilepsy in a mouse model of tuberous sclerosis complex. Ann Neurol. 2008;63:444-453.