The effect of a minor constituent of essential oil from Citrus aurantium: The role of β-myrcene in preventing peptic ulcer disease

Chemico-Biological Interactions

Volumn 212, Issue 1, 2014, Pages 11-19

  Bonamin, Flavia ^a   Moraes, Thiago M ^a   Dos Santos, Raquel C ^a   Kushima, Hélio ^a   Faria, Felipe M ^b   Silva, Marcos A ^a   Junior, Ivan V ^a   Nogueira, Leonardo ^a   Bauab, Tais M ^a   Souza Brito, Alba R M ^b   Da Rocha, Lucia R M ^a   Hiruma Lima, Clélia A ^a  

^a SÃO PAULO STATE UNIVERSITY UNESP   (Brazil)

^b UNIVERSITY OF CAMPINAS   (Brazil)

Author keywords

Antioxidant effects; beta; Myrcene; Gastroprotection; Helicobacter pylori; Peptic ulcer

Indexed keywords

ANTIOXIDANT EFFECTS; GASTROPROTECTION; HELICOBACTER PYLORI; PEPTIC ULCER; Β-MYRCENE;

ANIMALS; ANTI-ULCER AGENTS; CITRUS; MALE; MONOTERPENES; OILS, VOLATILE; PEPTIC ULCER; RATS; RATS, WISTAR;

EID: 84893919382     PISSN: 00092797     EISSN: 18727786     Source Type: Journal    
DOI: 10.1016/j.cbi.2014.01.009     Document Type: Article

References (48)

1. H.E. Vonkeman, R.M. Klok, M.J. Postma, J.R. Brouwers, and M.A. Van de Laar Direct medical costs of serious gastrointestinal ulcers among users of NSAID Drugs Aging 24 2007 681 690 (Pubitemid 47294715)
2. R.S. Tang, and F.K. Chan Therapeutic management of recurrent peptic ulcer disease Drugs 72 2012 1605 1616
3. K. Ramakrishnan, and R.C. Salinas Peptic ulcer disease Am. Fam. Physician 76 2007 1005 1012
4. F. Saghaie, I. Karimi, A. Jouyban, and M. Samini Effects of captopril on the cysteamine-induced duodenal ulcer in the rat Exp. Toxicol. Pathol. 64 2012 373 377
5. B. Halliwell, and J.M.C. Gutteridge Free Radicals in Biology and Medicine fourth ed. 2006 Oxford University Press UK
6. E. Günther, D. Althausen, ß-myrcene, in: E. Günther (Ed.), The Essential Oils. The Constituents of Essential Oils. New York, 1949, pp. 8-10.
7. T.M. Moraes, H. Kushima, F.C. Moleiro, R.C. Santos, L.R.M. Rocha, M.O. Marques, W. Vilegas, and C.A. Hiruma-Lima Effects of limonene and essential oil from Citrus aurantium on gastric mucosa: role of prostaglandins and gastric mucus secretion Chem. Biol. Interact. 180 2009 499 505
8. A.Y. Leung Encyclopedia of Commom Natural Ingredients Used in Food, Drugs and Cosmetics third ed. 1980 Wiley New York
9. C.M. Polo, T.M. Moraes, C.H. Pellizzon, M.O. Marques, L.R. Rocha, and C.A. Hiruma-Lima Gastric ulcers in middle-aged rats: the healing effect of essential oil from Citrus aurantium L. (Rutaceae) Evid. Based Complement Altern. Med. 1 2012 20 doi: 10.1155/2012/509451
10. T.M. Moraes, A.L. Rozza, H. Kushima, C.H. Pellizzon, L.R.M. Rocha, and C.A. Hiruma-Lima Healing actions of essential oils from Citrus aurantium and d-limonene in the gastric Mucosa: the roles of VEGF, PCNA, and COX-2 in cell proliferation J. Med. Food 16 2013 1162 1167
11. H. Wagner Multitarget therapy - the future of treatment for more than just functional dyspepsia Phytomedicine 13 2006 122 129 (Pubitemid 44816466)
12. H.Y. Chen, X.L. Ye, X.L. Cui, K. He, Y.N. Jin, Z. Chen, and X.G. Li Cytotoxicity and antihyperglycemic effect of minor constituents from Rhizoma coptis in HepG2 cells Fitoterapia 83 2011 67 73
13. E.D. Olfert, B.M. Cross, and A.A. McWilliam Guide to the Care and Use of Experimental Animals 1993 Canadian Council on Animal Care Ottawa, Ontario pp. 1-213
14. A. Robert, J.E. Nezamis, C. Lancaster, and A.J. Hanchar Cytoprotection by prostaglandins in rats: prevention of gastric necrosis produced by alcohol, HCI, NaOH, hypertonic NaCI and thermal injury Gastroenterology 77 1979 433 443 (Pubitemid 10132046)
15. K.D. Rainsford Gastric ulcerogenicity of non-steroidal anti-inflammatory drugs in mice with mucosa sensitized by cholinomimetic treatment J. Pharmacol. 39 1987 669 672 (Pubitemid 17116321)
16. J.C. Allen, and R.J. Halimton Rancidity and Foods 2000 Blackie Academic and Professional London, UK
17. R. Alder Breakdown in Human Adaptation to Stress 1984 Martinus Ninjihoff Boston 653
18. S. Ueda, T. Yoshikawa, S. Takahashi, H. Ichikawa, M. Yasuda, H. Oyamada, T. Tanigawa, S. Sugino, and M. Kondo Role of free radicals and lipid peroxidation in gastric mucosal injury induced by ischemia-reperfusion in rats Scand. J. Gastroenterol. 162 1989 55 58 (Pubitemid 19220320)
19. S. Szabo Mechanisms of mucosal injury in the stomach and duodenum: time-sequence analysis of morphologic, functional, biochemical and histochemical studies Scand. J. Gastroenterol. 22 1987 21 28 (Pubitemid 17067080)
20. S. Rafatullah, M. Tariq, M.A. Al-Yahya, J.S. Mossa, and A.M. Ageel Evaluation of tumeric (Curcuma longa) for gastric and duodenal antiulcer activity in rats J. Ethnopharmacol. 29 1990 25 34 (Pubitemid 20115460)
21. G.H. Curtis, W.K. Macnaughton, D.G. Gall, and J.L. Wallace Intraluminal pH modulates gastric prostaglandin synthesis Can. J. Physiol. Pharmacol. 73 1995 130 134
22. H. Matsuda, Y. Li, and M. Yoshikawa Gastroprotection of escins Ia, Ib, Iia, And Iib ethanol-induced gastric mucosal lesions in rats Eur. J. Pharmacol. 373 1999 63 70 (Pubitemid 29306711)
23. H. Ohkawa, N. Ohishi, and K. Yagi Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction Anal. Biochem. 95 1979 351 358 (Pubitemid 9194347)
24. M. Anderson Determination of glutathione disulfide in biological samples Methods Enzymol. 113 1985 548 555 (Pubitemid 16195830)
25. T. Yoshikawa, Y. Naito, A. Kishi, T. Tomii, T. Kaneko, S. Linuma, H. Ichikawa, and M. Yasudaet Role of active oxygen, lipid peroxidation, and antioxidants in the pathogenesis of gastric mucosal injury induced by indomethacin in rats Gut 34 1993 732 737 (Pubitemid 23185094)
26. I. Carlberg, and B. Mannervik Glutathione reductase Methods Enzymol. 113 1985 484 490 (Pubitemid 16195819)
27. C.C. Winterbourn, R.E. Hawkins, M. Brian, and R.W. Carrell The estimation of red cell superoxide dismutase activity J. Lab. Clin. Med. 85 1975 337 341
28. J.E. Krawisz, P. Sharon, and W.F. Stenson Quantitative assay for acute intestinal inflammation based on myeloperoxidase activity. Assessment of inflammation in the rat and hamster model Gastroenterology 87 1984 1344 1350 (Pubitemid 15201434)
29. CLSI. Manual Clinical and Laboratory Standards Institute. Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically: approved standards-6a ed. Performance standards for antimicrobial susceptibility testing. Sixteenth informational supplement M100-S16 (tab 2J). Clinical and Laboratory Standards Institute, Wayne, PA, 2006.
30. A. Franke, S. Teyssen, and M.V. Singer Alcohol-related diseases of the esophagus and stomach Dig. Dis. Sci. 25 2005 204 213 (Pubitemid 43325919)
31. S. Siegmund Animal models in gastrointestinal alcohol research - a short appraisal of the different models and their results Best Pract. Res. Clin. Gastroenterol. 17 2003 519 542
32. M.G. Repetto, and S.F. Llesuy Antioxidant properties of natural compounds used in popular medicine for gastric ulcers Braz. J. Med. Biol. Res. 35 2002 523 534 (Pubitemid 34568220)
33. M.N. Gandhi, R.C. Siva, P. Pari, and G. Tejal Role of leukotrienes in NSAID induced gastric ulceration and inflammation in Wistar rats Asian Pac. J. Trop. Dis. 2012 215 219
34. J.L. Wallace Pathogenesis of NSAID-induced gastroduodenal mucosal injury Best Pract. Res. Clin. Gastroenterol. 15 2001 691 703 (Pubitemid 32982360)
35. J.L. Wallace, and D.N. Granger The cellular and molecular basis of gastric mucosal defense FASEB J. 10 1996 731 740 (Pubitemid 26172819)
36. D.A. Brodie, and H.M. Hanson A study of the factors involved in the production of gastric ulcers by the restraint technique Gastroenterology 38 1960 353 360
37. C. Ji, D. Fan, W. Li, L. Guo, Z. Liang, R. Xu, and J. Zhang Evaluation of the anti-ulcerogenic activity of the antidepressants duloxetine, amitriptyline, fluoxetine and mirtazapine in different models of experimental gastric ulcer in rats Eur. J. Pharmacol. 691 2012 46 51
38. L. Laine, K. Takeuchi, and A. Tarnawski Gastric mucosal defense and cytoprotection: bench to bedside Gastroenterology 135 2008 41 60 (Pubitemid 351899027)
39. D.M. Abdallah, H.S. El-Abhar, and D.H. Abdel-Aziz TEMPOL, a membrane permeable radical scavenger, attenuates gastric mucosal damage induced by ischemia-reperfusion: a key role for superoxide anion Eur. J. Pharmacol. 603 2009 93 97
40. J.L. Wallace, and M.J. Miller Nitric oxide in mucosal defense: a little goes a long way Gastroenterology 119 2000 512 520 (Pubitemid 30622002)
41. T. Khomenko, J. Kolodney, J.T. Pinto, G.D. McLaren, X. Deng, L. Chen, G. Tolstanova, B. Paunovic, B.F. Krasnikov, N. Hoa, A.J. Cooper, and S. Szabo New mechanistic explanation for the localization of ulcers in the rat duodenum: role of iron and selective uptake of cysteamine Arch. Biochem. Biophys. 525 2012 60 70
42. C.X. Ji, D.S. Fan, W. Li, L. Guo, Z.L. Xu, R.M. Liang, and J.J. Zhang Evaluation of the anti-ulcerogenic activity of the antidepressants duloxetine, amitriptyline, fluoxetine and mirtazapine in different models of experimental gastric ulcer in rats Eur. J. Pharmacol. 691 2012 46 51
43. A. Allen, and G. Flemstrom Gastroduodenal mucus bicarbonate barrier: protection against acid and pepsin Cell Physiol.: Am. J. Physiol. 288 2005 1 19
44. T. Brzozowski, P.C. Konturek, M. Mierzwa, D. Drozdowicz, W. Bielanski, S. Kwiecien, S.J. Konturek, J. Stachura, W.W. Pawlik, and E.G. Hahn Effect of probiotics and triple eradication therapy on the cyclooxygenase (COX)-2 expression, apoptosis, and functional gastric mucosal impairment in Helicobacter pylori-infected Mongolian gerbils Helicobacter 11 2006 10 20
45. S. Mei, H. Gu, X. Yang, H. Guo, Z. Liu, and W. Cao Prolonged exposure to insulin induces mitochondrion-derived oxidative stress through increasing mitochondrial cholesterol content in hepatocytes Endocrinology 153 2012 2120 2129
46. D. Mustacich, and G. Powis Thioredoxin reductase Biochem. J. 346 2000 1 8 (Pubitemid 30113812)
47. O. Ciftci, I. Ozdemir, S. Tanyildizi, S. Yildiz, and H. Ogozturk Antioxidantive effects of curcumin, β-myrcene, 1,8 cineole against 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced oxidative stress in rats liver Toxicol. Ind. Health 27 2011 447 453
48. G. Nervi, S. Liatopoulou, and L. Cavallaro Does Helicobacter pylori infection eradication modify peptic ulcer prevalence? A 10 years endoscopical survey World J. Gastroenterol. 12 2006 2398 2401