New mechanistic explanation for the localization of ulcers in the rat duodenum: Role of iron and selective uptake of cysteamine

Archives of Biochemistry and Biophysics

Volumn 525, Issue 1, 2012, Pages 60-70

  Khomenko, Tetyana ^a,b   Kolodney, Joanna ^a,b   Pinto, John T ^c   McLaren, Gordon D ^a,b   Deng, Xiaoming ^a,b   Chen, Longchuan ^a   Tolstanova, Ganna ^a,b   Paunovic, Brankica ^a   Krasnikov, Boris F ^c   Hoa, Neil ^a   Cooper, Arthur J L ^c   Szabo, Sandor ^a,b  

^a VA LONG BEACH HEALTHCARE SYSTEM   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c NEW YORK MEDICAL COLLEGE   (United States)

Author keywords

Cysteamine absorption; Cysteamine induced duodenal ulcers; Iron; Organic cation transporters; ROS production

Indexed keywords

HISTAMINE RECEPTOR; IRON; MERCAPTAMINE; ORGANIC CATION TRANSPORTER; REACTIVE OXYGEN METABOLITE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DUODENUM ULCER; GASTROINTESTINAL MUCOSA; GASTROINTESTINAL TRACT; GENE EXPRESSION; IN VITRO STUDY; INTESTINE EPITHELIUM CELL; NONHUMAN; PH; PRIORITY JOURNAL; RAT;

ANIMALS; BIOLOGICAL TRANSPORT; CACO-2 CELLS; CYSTAMINE; CYSTEAMINE; DEFEROXAMINE; DUODENAL ULCER; DUODENUM; FEMALE; GENE EXPRESSION REGULATION; HUMANS; INTESTINAL ABSORPTION; INTESTINAL MUCOSA; INTRACELLULAR SPACE; IRON; IRON CHELATING AGENTS; MICE; ORGAN SPECIFICITY; ORGANIC CATION TRANSPORT PROTEINS; RATS; REACTIVE OXYGEN SPECIES; SODIUM;

MUS; RATTUS; RODENTIA;

EID: 84864191003     PISSN: 00039861     EISSN: 10960384     Source Type: Journal    
DOI: 10.1016/j.abb.2012.05.013     Document Type: Article

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