Phenotypic expression, molecular characterization and transferability of erythromycin resistance genes in Enterococcus spp. isolated from naturally fermented food

Journal of Applied Microbiology

Volumn 116, Issue 3, 2014, Pages 689-699

  Thumu, S C R ^a   Halami, P M ^a  

^a CENTRAL FOOD TECHNOLOGICAL RESEARCH INSTITUTE   (India)

Author keywords

Conjugation; Enterococcus; Erythromycin; Fermented foods; Tetracycline resistance

Indexed keywords

BACILLI; DNA; GENE EXPRESSION;

CONJUGATION; ENTEROCOCCUS; ERYTHROMYCIN; ERYTHROMYCIN RESISTANCE; FERMENTED FOODS; LINCOSAMIDE; MACROLIDES; RESISTANCE GENES; STREPTOGRAMINS; TETRACYCLINE RESISTANCE;

ANTIBIOTICS;

AZITHROMYCIN; BACTERIAL PROTEIN; CLARITHROMYCIN; CLINDAMYCIN; ERM PROTEIN; ERYTHROMYCIN; MIKAMYCIN B; MSR PROTEIN; PRISTINAMYCIN; RIFAMPICIN; TETRACYCLINE; UNCLASSIFIED DRUG; ANTIINFECTIVE AGENT; LINCOSAMIDE; MACROLIDE;

ANTIBIOTIC RESISTANCE; BACTERIUM; CHROMOSOME; GENE EXPRESSION; INHIBITION; MOLECULAR ANALYSIS; PHENOTYPE;

ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIAL CHROMOSOME; BACTERIUM CONTAMINATION; BACTERIUM ISOLATION; CHROMOSOME ANALYSIS; CONJUGATION; CROSS RESISTANCE; DISK DIFFUSION; ENTEROCOCCAL INFECTION; ENTEROCOCCUS; ENTEROCOCCUS CASSELIFLAVUS; ENTEROCOCCUS DURANS; ENTEROCOCCUS FAECALIS; ENTEROCOCCUS FAECIUM; FERMENTED PRODUCT; GENETIC SCREENING; IN VITRO STUDY; MINIMUM INHIBITORY CONCENTRATION; MOLECULAR DYNAMICS; MOLECULAR WEIGHT; NONHUMAN; PHENOTYPE; PLASMID; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; SOUTHERN BLOTTING; BACTERIAL GENE; BACTERIUM CONJUGATION; DRUG EFFECTS; FERMENTATION; FOOD CONTROL; GENETICS; ISOLATION AND PURIFICATION;

ANTI-BACTERIAL AGENTS; CLINDAMYCIN; CONJUGATION, GENETIC; DRUG RESISTANCE, BACTERIAL; ENTEROCOCCUS; ERYTHROMYCIN; FERMENTATION; FOOD MICROBIOLOGY; GENES, BACTERIAL; LINCOSAMIDES; MACROLIDES; PHENOTYPE; PLASMIDS; STREPTOGRAMIN GROUP B;

EID: 84893904140     PISSN: 13645072     EISSN: 13652672     Source Type: Journal    
DOI: 10.1111/jam.12386     Document Type: Article

References (39)

1. Aarestrup, F.M., Agerso, Y., Gerner-Smidt, P., Madsen, M. and Jensen, L.B. (2000) Comparison of antimicrobial resistance phenotypes and resistance genes in Enterococcus faecalis and Enterococcus faecium from humans in the community, broilers, and pigs in Denmark. Diagn Microbiol Infect Dis 37, 127-137.
2. Aarestrup, F.M., Butaye, P. and Witte, W. (2002) Nonhuman reservoirs of enterococci. In The Enterococci: pathogenesis, Molecular Biology, and Antibiotic Resistance ed. Gilmore, M.S., Clewell, D.B., Courvalin, P., Dunny, G.M., Murrau, B.E. and Rice, L.B. pp. 55-99. Washington, DC: ASM.
3. Aeschlimann, J.R., Zervos, M.J. and Rybak, M.J. (1998) Treatment of vancomycin resistant Enterococcus faecium with RP59500 (quinipristin-dalfopristin) administered by intermittent or continuous infusion, alone or in combination with doxycycline, in an in vitro pharmacodynamic infection model with simulated endocardial vegetation. Antimicrob Agents Chemother 42, 2710-2717.
4. Anderson, D.G. and McKay, L.L. (1983) Simple and rapid method for isolating large plasmid DNA from lactic streptococci. Appl Environ Microbiol 46, 549-552.
5. Bailey, M., Chettiah, T. and Mankin, A.S. (2008) Induction of ermC expression by noninducing antibiotics. Antimicrob Agents Chemother 52, 866-874.
6. Chajecka-Wierzchowska, W., Zadernowska, A., Nalepa, B. and Laniewska-Trokenheim, L. (2012) Occurrence and antibiotic resistance of enterococci in ready-to-eat food of animal origin. Afr J Microbiol Res 6, 6773-6780.
7. Chomezynski, P. (1992) One-hour downward alkaline capillary transfer for blotting of DNA and RNA. Anal Biochem 201, 134-139.
8. Clinical Laboratory Standard Institute (CLSI). (2012) Performance standard for antimicrobial testing; Twenty second informational supplement, M100-S22.
9. De Graef, E.M., Decostere, A., De Leener, E., Goossens, H., Baele, M. and Haesebrouck, F. (2007) Prevalence and mechanism of resistance against macrolides, lincosamides, and streptogramins among Enterococcus faecium isolates from food-producing animals and hospital patients in Belgium. Microb Drug Resis 13, 135-141.
10. Edwards, D.D. (2000) Enterococci attract attention of concerned microbiologists. ASM News 66, 540-545.
11. Enne, V.I., Delsol, A.A., Roe, J.M. and Bennett, P.M. (2004) Rifampicin resistance and its fitness cost in Enterococcus faecium. J Antimicrob Chemother 53, 203-207.
12. EUCAST. (2011) European Committee on Antimicrobial Susceptibility Testing, Breakpoint tables for interpretation of MICs and zone diameters. Version 1.3
13. Ganguly, N.K., Arora, N.K., Chandy, S.J., Fairoze, M.N., Gill, J.P.S., Gupta, U., Hossain, S., Joglekar, S. et al. (2011) Rationalizing antibiotic use to limit antibiotic resistance in India. Indian J Med Res 134, 281-294.
14. Gevers, D., Huys, G. and Swings, J. (2003) In vitro conjugal transfer of tetracycline resistance from Lactobacillus isolates to other Gram-positive bacteria. FEMS Microbiol Lett 225, 125-130.
15. Gygax, S.E., Schuyler, J.A., Kimmel, L.E., Trama, J.P., Mordechai, E. and Adelson, M.E. (2006) Erythromycin and clindamycin resistance in group B streptococcal clinical isolates. Antimicrob Agents Chemother 46, 1875-1877.
16. Hayes, J.R., English, L.L., Carter, P.J., Proescholdt, T., Lee, K.Y., Wagner, D.D. and White, D.G. (2003) Prevalence and antimicrobial resistance of Enterococcus species isolated from retail meats. Appl Environ Microbiol 69, 7153-7160.
17. Hayes, J.R., English, L.L., Carr, L.E., Wagner, D.D. and Joseph, S.W. (2004) Multiple-antibiotic resistance of Enterococcus spp. isolated from commercial poultry production environments. Appl Environ Microbiol 70, 6005-6011.
18. Hershberger, E., Donabedian, S., Konstantinou, K. and Zervos, M.J. (2004) Quinipristin-Dalfopristin resistance in Gram-positive bacteria: mechanism of resistance and epidemiology. Clin Infect Dis 28, 92-98.
19. Hidron, A.I., Edwards, J.R., Patel, J., Horan, T.C., Sievert, D.M., Pollock, D.A., Fridkin, S.K., Team, N.H.S.N. et al. (2008) NHSN annual update: antimicrobial-resistant pathogens associated with healthcare-associated infections: annual summary of data reported to the national healthcare safety network at the centers for disease control and prevention, 2006-2007. Infect Control Hosp Epidemiol 29, 996-1011.
20. Jamet, E., Akary, E., Poisson, M., Chamba, J., Bertrand, X. and Serror, P. (2012) Prevalence and characterization of antibiotic resistant Enterococcus faecalis in French cheeses. Food Microbiol 31, 191-198.
21. Koluman, A., Akan, L.S. and Çakiroǧlu, F.P. (2009) Occurrence and antimicrobial resistance of enterococci in retail foods. Food Control 20, 281-283.
22. Leclercq, R. and Courvalin, P. (1991) Bacterial resistance to macrolide, lincosamide, and streptogramin antibiotics by target modification. Antimicrob Agents Chemother 35, 1267-1272.
23. Liu, Y., Liu, K., Lai1, J., Wu, C., Shen, J. and Wang, Y. (2012) Prevalence and antimicrobial resistance of Enterococcus species of food animal origin from Beijing and Shandong Province, China. J Appl Microbiol 114, 555-563.
24. Mora, D., Fortina, M.G., Parini, C., Daffonchio, D. and Manachini, P.L. (2000) Genomic sub-populations within the species Pediococcus acidilactici detected multilocus typing analysis: relationships between pediocin AcH/PA-1 producing and non-producing strains. Microbiology 46, 2027-2038.
25. Novais, C., Coque, T.M., Costa, M.J., Sousa, J.C., Baquero, F. and Peixe, L.V. (2005) High occurrence and persistence of antibiotic-resistant enterococci in poultry food samples in Portugal. J Antimicrob Chemother 56, 1139-1143.
26. Noyal, M.J.C., Menezes, G.A., Harish, B.N., Sujatha, S. and Parija, S.C. (2009) Simple screening tests for detection of carbapenemases in clinical isolates of nonfermentative Gram-negative bacteria. Indian J Med Res 129, 707-712.
27. Ogier, J.C. and Serror, P. (2008) Safety assessment of dairy microorganisms: the Enterococcus genus. Int J Food Microbiol 126, 291-301.
28. Portillo, A., Ruiz-Larrea, F., Zarazaga, M., Alanso, A., Martinez, L.J. and Torres, C. (2000) Macrolide resistance genes in Enterococcus spp. Antimicrob Agents Chemother 44, 967-971.
29. Reynolds, E. and Cove, J.H. (2005) Enhanced resistance to erythromycin is conferred by the enterococcal msrC determinant in Staphylococcus aureus. J Antimicrob Chemother 55, 260-264.
30. Roberts, M.C. (2008) Update on macrolide-licosamide-streptogramin, ketolide, and oxazolidinone resistance genes. FEMS Microbiol Lett 282, 147-159.
31. Schwaiger, K., Helmke, K., Hölzel, C.S. and Bauer, J. (2011) Antibiotic resistance in bacteria isolated from vegetables with regards to the marketing stage (farm vs. supermarket). Int J Food Microbiol 148, 191-196.
32. Seppala, H., Nissinen, A., Yu, Q. and Huovinen, P. (1993) Three different phenotypes of erythromycin resistant Streptococcus pyogenes in Finland. J Antimicrob Chemother 32, 885-891.
33. Sood, S., Malhotra, M., Das, B.K. and Kapil, A. (2008) Enterococcal infections & antimicrobial resistance. Indian J Med Res 128, 111-121.
34. Srinivasan, U., Miller, B., Debusscher, J., Marrs, C.F., Zhang, L., Seo, Y.S., Oh, K.Y., Kim, M.Y. et al. (2011) Identification of a novel keyhole phenotype in double-disc diffusion assays of clindamycin-resistant erythromycin sensitive strains of Streptococcus agalactiae. Microb Drug Resis 17, 121-124.
35. Teuber, M., Meile, L. and Schwarz, F. (1999) Acquired antibiotic resistance in lactic acid bacteria from food. Antonie Van Leeuwenhoek 76, 115-137.
36. Thumu, S.C.R. and Halami, P.M. (2012) Presence of erythromycin and tetracycline resistance genes in lactic acid bacteria from fermented foods of Indian origin. Antonie Van Leeuwenhoek 102, 541-551.
37. Tremblay, C., Letellier, A., Quessy, S., Boulianne, M., Daignault, D. and Archambault, M. (2011) Multiple-antibiotic resistance of Enterococcus faecalis and Enterococcus faecium from cecal contents in broiler chicken and Turkey flocks slaughtered in Canada and plasmid co-localization of tetO and ermB genes. J Food Prot 74, 1639-1648.
38. Wierzbowski, A.K., Boyd, D., Mulvey, M., Hoban, D.J. and Zhanel, G.G. (2005) Expression of the mef(E) gene encoding the macrolide efflux pump protein increases in Streptococcus pneumoniae with increasing resistance to macrolides. Antimicrob Agents Chemother 49, 4635-4640.
39. Zaheer, R., Cook, S.R., Klima1, C.L., Stanford, K., Alexander, T., Topp, E., Read, R.R. and Mc Allister, T.A. (2013) Effect of sub therapeutic vs. therapeutic administration of macrolides on antimicrobial resistance in Mannheimia haemolytica and enterococci isolated from beef cattle. Front Microbiol 4, 1-14.