SIRT1 limits the function and fate of myeloid-derived suppressor cells in tumors by orchestrating HIF-1α-dependent glycolysis

Cancer Research

Volumn 74, Issue 3, 2014, Pages 727-737

  Liu, Guangwei ^a,c   Bi, Yujing ^d   Shen, Bo ^b   Yang, Hui ^a,c   Zhang, Yan ^a,c   Wang, Xiao ^a,c   Liu, Huanrong ^a,c   Lu, Yun ^a,c   Liao, Jiongbo ^a,c   Chen, Xi ^a,c   Chu, Yiwei ^a,c  

^a BEIJING UNIVERSITY OF POSTS AND TELECOMMUNICATIONS   (China)

^b Institute of Radiomedicine   (China)

^c FUDAN UNIVERSITY   (China)

^d BEIJING INSTITUTE OF MICROBIOLOGY AND EPIDEMIOLOGY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

HYPOXIA INDUCIBLE FACTOR 1ALPHA; MAMMALIAN TARGET OF RAPAMYCIN; SIRTUIN 1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER PREVENTION; CARCINOGENESIS; CELL DIFFERENTIATION; CELL FATE; CELL FUNCTION; CELL LINEAGE; CONTROLLED STUDY; GLYCOLYSIS; INFLAMMATION; MOUSE; MYELOID DERIVED SUPPRESSOR CELL; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DEFICIENCY; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; SUPPRESSOR CELL; TUMOR ASSOCIATED LEUKOCYTE; TUMOR CELL DESTRUCTION; TUMOR GROWTH;

ANIMALS; ANOXIA; CELL DIFFERENTIATION; DISEASE MODELS, ANIMAL; GLYCOLYSIS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; MELANOMA, EXPERIMENTAL; METABOLIC NETWORKS AND PATHWAYS; MICE; MICE, KNOCKOUT; MYELOID CELLS; NEOPLASMS; SIRTUIN 1; SPLEEN; TOR SERINE-THREONINE KINASES; TUMOR BURDEN;

EID: 84893873953     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-13-2584     Document Type: Article

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