Role of anti-CD40 antibody-mediated costimulation blockade on non-Gal antibody production and heterotopic cardiac xenograft survival in a GTKO.hCD46Tg pig-to-baboon model

Xenotransplantation

Volumn 21, Issue 1, 2014, Pages 35-45

  Mohiuddin, Muhammad M ^a   Singh, Avneesh K ^a   Corcoran, Philip C ^a   Hoyt, Robert F ^a   Thomas III, Marvin L ^b   Lewis, Billeta G T ^b   Eckhaus, Michael ^b   Dabkowski, Nicole L ^c   Belli, Aaron J ^c   Reimann, Keith A ^c   Ayares, David ^d   Horvath, Keith A ^a  

^a NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

^b NATIONAL INSTITUTES OF HEALTH   (United States)

^c UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^d REVIVICOR INC   (United States)

Author keywords

2C10R4; Anti CD40 antibody; cardiac xenograft; CD46; Gal KO pigs; non Gal antibodies; xenotransplantation

Indexed keywords

ANTIBODY; CD40 ANTIGEN; CD40 LIGAND; IMMUNOSUPPRESSIVE AGENT;

ANIMAL; ANTIBODY PRODUCTION; B LYMPHOCYTE; BABOON; GRAFT REJECTION; GRAFT SURVIVAL; IMMUNOLOGY; PIG; PROCEDURES; TRANSGENIC ANIMAL; XENOGRAFT;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; ANTIBODIES; ANTIBODY FORMATION; ANTIGENS, CD40; B-LYMPHOCYTES; CD40 LIGAND; GRAFT REJECTION; GRAFT SURVIVAL; HETEROGRAFTS; IMMUNOSUPPRESSIVE AGENTS; PAPIO; SUS SCROFA; SWINE; TRANSPLANTATION, HETEROLOGOUS;

EID: 84893855969     PISSN: 0908665X     EISSN: 13993089     Source Type: Journal    
DOI: 10.1111/xen.12066     Document Type: Article

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