메뉴 건너뛰기




Volumn 9, Issue 3, 2014, Pages 779-785

The role of claudin-5 in blood-brain barrier (BBB) and brain metastases (Review)

Author keywords

Blood brain barrier; Brain metastases; Claudin 5; Claudins; Permeability; Tight junctions

Indexed keywords

BLOOD-BRAIN BARRIER; BRAIN NEOPLASMS; CLAUDIN-5; ENDOTHELIAL CELLS; HUMANS; JUNCTIONAL ADHESION MOLECULES; NEOPLASM METASTASIS; TIGHT JUNCTIONS;

EID: 84893844241     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr.2013.1875     Document Type: Article
Times cited : (134)

References (72)
  • 1
    • 84878654284 scopus 로고    scopus 로고
    • Role of the blood-brain barrier in the formation of brain metastases
    • Wilhelm I, Molnár J, Fazakas C, Haskó J and Krizbai IA: Role of the blood-brain barrier in the formation of brain metastases. Int J Mol Sci 14: 1383-1411, 2013.
    • (2013) Int J Mol Sci , vol.14 , pp. 1383-1411
    • Wilhelm, I.1    Molnár, J.2    Fazakas, C.3    Haskó, J.4    Krizbai, I.A.5
  • 2
    • 0022005333 scopus 로고
    • Epidemiology of brain tumors: The national survey of intracranial neoplasms
    • Walker AE, Robins M and Weinfeld FD: Epidemiology of brain tumors: the national survey of intracranial neoplasms. Neurology 35: 219-226, 1985.
    • (1985) Neurology , vol.35 , pp. 219-226
    • Walker, A.E.1    Robins, M.2    Weinfeld, F.D.3
  • 3
    • 27644546807 scopus 로고    scopus 로고
    • Brain metastases: Epidemiology and pathophysiology
    • Gavrilovic IT and Posner JB: Brain metastases: epidemiology and pathophysiology. J Neurooncol 75: 5-14, 2005.
    • (2005) J Neurooncol , vol.75 , pp. 5-14
    • Gavrilovic, I.T.1    Posner, J.B.2
  • 4
    • 0037093972 scopus 로고    scopus 로고
    • Incidence of brain metastases in a cohort of patients with carcinoma of the breast, colon, kidney, and lung and melanoma
    • Schouten LJ, Rutten J, Huveneers HA and Twijnstra A: Incidence of brain metastases in a cohort of patients with carcinoma of the breast, colon, kidney, and lung and melanoma. Cancer 94: 2698-2705, 2002.
    • (2002) Cancer , vol.94 , pp. 2698-2705
    • Schouten, L.J.1    Rutten, J.2    Huveneers, H.A.3    Twijnstra, A.4
  • 5
    • 84857034419 scopus 로고    scopus 로고
    • Brain metastases: Pathobiology and emerging targeted therapies
    • Preusser M, Capper D, Ilhan-Mutlu A, et al: Brain metastases: pathobiology and emerging targeted therapies. Acta Neuropathol 123: 205-222, 2012.
    • (2012) Acta Neuropathol , vol.123 , pp. 205-222
    • Preusser, M.1    Capper, D.2    Ilhan-Mutlu, A.3
  • 6
    • 4344694453 scopus 로고    scopus 로고
    • Incidence proportions of brain metastases in patients diagnosed (1973 to 2001) in the Metropolitan Detroit Cancer Surveillance System
    • Barnholtz-Sloan JS, Sloan AE, Davis FG, Vigneau FD, Lai P and Sawaya RE: Incidence proportions of brain metastases in patients diagnosed (1973 to 2001) in the Metropolitan Detroit Cancer Surveillance System. J Clin Oncol 22: 2865-2872, 2004.
    • (2004) J Clin Oncol , vol.22 , pp. 2865-2872
    • Barnholtz-Sloan, J.S.1    Sloan, A.E.2    Davis, F.G.3    Vigneau, F.D.4    Lai, P.5    Sawaya, R.E.6
  • 7
    • 77956620769 scopus 로고    scopus 로고
    • Current treatment strategies for brain metastasis and complications from therapeutic techniques: A review of current literature
    • Platta CS, Khuntia D, Mehta MP and Suh JH: Current treatment strategies for brain metastasis and complications from therapeutic techniques: a review of current literature. Am J Clin Oncol 33: 398-407, 2010.
    • (2010) Am J Clin Oncol , vol.33 , pp. 398-407
    • Platta, C.S.1    Khuntia, D.2    Mehta, M.P.3    Suh, J.H.4
  • 11
    • 75049084451 scopus 로고    scopus 로고
    • The role of whole brain radiation therapy in the management of newly diagnosed brain metastases: A systematic review and evidence-based clinical practice guideline
    • Gaspar LE, Mehta MP, Patchell RA, et al: The role of whole brain radiation therapy in the management of newly diagnosed brain metastases: a systematic review and evidence-based clinical practice guideline. J Neurooncol 96: 17-32, 2010.
    • (2010) J Neurooncol , vol.96 , pp. 17-32
    • Gaspar, L.E.1    Mehta, M.P.2    Patchell, R.A.3
  • 12
    • 74949144656 scopus 로고    scopus 로고
    • The role of stereotactic radiosurgery in the management of patients with newly diagnosed brain metastases: A systematic review and evidence-based clinical practice guideline
    • Linskey ME, Andrews DW, Asher AL, et al: The role of stereotactic radiosurgery in the management of patients with newly diagnosed brain metastases: a systematic review and evidence-based clinical practice guideline. J Neurooncol 96: 45-68, 2010.
    • (2010) J Neurooncol , vol.96 , pp. 45-68
    • Linskey, M.E.1    Andrews, D.W.2    Asher, A.L.3
  • 13
    • 75049084643 scopus 로고    scopus 로고
    • The role of chemotherapy in the management of newly diagnosed brain metastases: A systematic review and evidence-based clinical practice guideline
    • Mehta MP, Paleologos NA, Mikkelsen T, et al: The role of chemotherapy in the management of newly diagnosed brain metastases: a systematic review and evidence-based clinical practice guideline. J Neurooncol 96: 71-83, 2010.
    • (2010) J Neurooncol , vol.96 , pp. 71-83
    • Mehta, M.P.1    Paleologos, N.A.2    Mikkelsen, T.3
  • 14
    • 75049083726 scopus 로고    scopus 로고
    • The role of surgical resection in the management of newly diagnosed brain metastases: A systematic review and evidence-based clinical practice guideline
    • Kalkanis SN, Kondziolka D, Gaspar LE, et al: The role of surgical resection in the management of newly diagnosed brain metastases: a systematic review and evidence-based clinical practice guideline. J Neurooncol 96: 33-43, 2010.
    • (2010) J Neurooncol , vol.96 , pp. 33-43
    • Kalkanis, S.N.1    Kondziolka, D.2    Gaspar, L.E.3
  • 15
    • 75049083262 scopus 로고    scopus 로고
    • The role of emerging and investigational therapies for metastatic brain tumors: A systematic review and evidence-based clinical practice guideline of selected topics
    • Olson JJ, Paleologos NA, Gaspar LE, et al: The role of emerging and investigational therapies for metastatic brain tumors: a systematic review and evidence-based clinical practice guideline of selected topics. J Neurooncol 96: 115-142, 2010.
    • (2010) J Neurooncol , vol.96 , pp. 115-142
    • Olson, J.J.1    Paleologos, N.A.2    Gaspar, L.E.3
  • 16
    • 84869870044 scopus 로고    scopus 로고
    • Biology of brain metastases and novel targeted therapies: Time to translate the research
    • Fokas E, Steinbach JP and Rödel C: Biology of brain metastases and novel targeted therapies: time to translate the research. Biochim Biophys Acta 1835: 61-75, 2013.
    • (2013) Biochim Biophys Acta , vol.1835 , pp. 61-75
    • Fokas, E.1    Steinbach, J.P.2    Rödel, C.3
  • 17
    • 70450263474 scopus 로고    scopus 로고
    • Cellular elements of the blood-brain barrier
    • Correale J and Villa A: Cellular elements of the blood-brain barrier. Neurochem Res 34: 2067-2077, 2009.
    • (2009) Neurochem Res , vol.34 , pp. 2067-2077
    • Correale, J.1    Villa, A.2
  • 18
    • 0021972672 scopus 로고
    • Endothelial fenestral diaphragms: A quick-freeze, deep-etch study
    • Bearer EL and Orci L: Endothelial fenestral diaphragms: a quick-freeze, deep-etch study. J Cell Biol 100: 418-428, 1985.
    • (1985) J Cell Biol , vol.100 , pp. 418-428
    • Bearer, E.L.1    Orci, L.2
  • 19
    • 0014481056 scopus 로고
    • Junctions between intimately apposed cell membranes in the vertebrate brain
    • Brightman MW and Reese TS: Junctions between intimately apposed cell membranes in the vertebrate brain. J Cell Biol 40: 648-677, 1969.
    • (1969) J Cell Biol , vol.40 , pp. 648-677
    • Brightman, M.W.1    Reese, T.S.2
  • 20
    • 0026581496 scopus 로고
    • Structural domains of the tight junctional intramembrane fibrils
    • Lane NJ, Reese TS and Kachar B: Structural domains of the tight junctional intramembrane fibrils. Tissue Cell 24: 291-300, 1992.
    • (1992) Tissue Cell , vol.24 , pp. 291-300
    • Lane, N.J.1    Reese, T.S.2    Kachar, B.3
  • 21
    • 0027394873 scopus 로고
    • Transcytosis of protein through the mammalian cerebral epithelium and endothelium. II. Adsorptive transcytosis of WGA-HRP and the blood-brain and brain-blood barriers
    • Villegas JC and Broadwell RD: Transcytosis of protein through the mammalian cerebral epithelium and endothelium. II. Adsorptive transcytosis of WGA-HRP and the blood-brain and brain-blood barriers. J Neurocytol 22: 67-80, 1993.
    • (1993) J Neurocytol , vol.22 , pp. 67-80
    • Villegas, J.C.1    Broadwell, R.D.2
  • 22
    • 84878654284 scopus 로고    scopus 로고
    • Role of the blood-brain barrier in the formation of brain metastases
    • Wilhelm I, Molnár J, Fazakas C, Haskó J and Krizbai IA: Role of the blood-brain barrier in the formation of brain metastases. Int J Mol Sci 14: 1383-1411, 2013.
    • (2013) Int J Mol Sci , vol.14 , pp. 1383-1411
    • Wilhelm, I.1    Molnár, J.2    Fazakas, C.3    Haskó, J.4    Krizbai, I.A.5
  • 23
    • 0022005333 scopus 로고
    • Epidemiology of brain tumors: The national survey of intracranial neoplasms
    • Walker AE, Robins M and Weinfeld FD: Epidemiology of brain tumors: the national survey of intracranial neoplasms. Neurology 35: 219-226, 1985.
    • (1985) Neurology , vol.35 , pp. 219-226
    • Walker, A.E.1    Robins, M.2    Weinfeld, F.D.3
  • 24
    • 27644546807 scopus 로고    scopus 로고
    • Brain metastases: Epidemiology and pathophysiology
    • Gavrilovic IT and Posner JB: Brain metastases: epidemiology and pathophysiology. J Neurooncol 75: 5-14, 2005.
    • (2005) J Neurooncol , vol.75 , pp. 5-14
    • Gavrilovic, I.T.1    Posner, J.B.2
  • 25
    • 0037093972 scopus 로고    scopus 로고
    • Incidence of brain metastases in a cohort of patients with carcinoma of the breast, colon, kidney, and lung and melanoma
    • Schouten LJ, Rutten J, Huveneers HA and Twijnstra A: Incidence of brain metastases in a cohort of patients with carcinoma of the breast, colon, kidney, and lung and melanoma. Cancer 94: 2698-2705, 2002.
    • (2002) Cancer , vol.94 , pp. 2698-2705
    • Schouten, L.J.1    Rutten, J.2    Huveneers, H.A.3    Twijnstra, A.4
  • 26
    • 84857034419 scopus 로고    scopus 로고
    • Brain metastases: Pathobiology and emerging targeted therapies
    • Preusser M, Capper D, Ilhan-Mutlu A, et al: Brain metastases: pathobiology and emerging targeted therapies. Acta Neuropathol 123: 205-222, 2012.
    • (2012) Acta Neuropathol , vol.123 , pp. 205-222
    • Preusser, M.1    Capper, D.2    Ilhan-Mutlu, A.3
  • 27
    • 4344694453 scopus 로고    scopus 로고
    • Incidence proportions of brain metastases in patients diagnosed (1973 to 2001) in the Metropolitan Detroit Cancer Surveillance System
    • Barnholtz-Sloan JS, Sloan AE, Davis FG, Vigneau FD, Lai P and Sawaya RE: Incidence proportions of brain metastases in patients diagnosed (1973 to 2001) in the Metropolitan Detroit Cancer Surveillance System. J Clin Oncol 22: 2865-2872, 2004.
    • (2004) J Clin Oncol , vol.22 , pp. 2865-2872
    • Barnholtz-Sloan, J.S.1    Sloan, A.E.2    Davis, F.G.3    Vigneau, F.D.4    Lai, P.5    Sawaya, R.E.6
  • 28
    • 77956620769 scopus 로고    scopus 로고
    • Current treatment strategies for brain metastasis and complications from therapeutic techniques: A review of current literature
    • Platta CS, Khuntia D, Mehta MP and Suh JH: Current treatment strategies for brain metastasis and complications from therapeutic techniques: a review of current literature. Am J Clin Oncol 33: 398-407, 2010.
    • (2010) Am J Clin Oncol , vol.33 , pp. 398-407
    • Platta, C.S.1    Khuntia, D.2    Mehta, M.P.3    Suh, J.H.4
  • 32
    • 75049084451 scopus 로고    scopus 로고
    • The role of whole brain radiation therapy in the management of newly diagnosed brain metastases: A systematic review and evidence-based clinical practice guideline
    • Gaspar LE, Mehta MP, Patchell RA, et al: The role of whole brain radiation therapy in the management of newly diagnosed brain metastases: a systematic review and evidence-based clinical practice guideline. J Neurooncol 96: 17-32, 2010.
    • (2010) J Neurooncol , vol.96 , pp. 17-32
    • Gaspar, L.E.1    Mehta, M.P.2    Patchell, R.A.3
  • 33
    • 74949144656 scopus 로고    scopus 로고
    • The role of stereotactic radiosurgery in the management of patients with newly diagnosed brain metastases: A systematic review and evidence-based clinical practice guideline
    • Linskey ME, Andrews DW, Asher AL, et al: The role of stereotactic radiosurgery in the management of patients with newly diagnosed brain metastases: a systematic review and evidence-based clinical practice guideline. J Neurooncol 96: 45-68, 2010.
    • (2010) J Neurooncol , vol.96 , pp. 45-68
    • Linskey, M.E.1    Andrews, D.W.2    Asher, A.L.3
  • 34
    • 75049084643 scopus 로고    scopus 로고
    • The role of chemotherapy in the management of newly diagnosed brain metastases: A systematic review and evidence-based clinical practice guideline
    • Mehta MP, Paleologos NA, Mikkelsen T, et al: The role of chemotherapy in the management of newly diagnosed brain metastases: a systematic review and evidence-based clinical practice guideline. J Neurooncol 96: 71-83, 2010.
    • (2010) J Neurooncol , vol.96 , pp. 71-83
    • Mehta, M.P.1    Paleologos, N.A.2    Mikkelsen, T.3
  • 35
    • 75049083726 scopus 로고    scopus 로고
    • The role of surgical resection in the management of newly diagnosed brain metastases: A systematic review and evidence-based clinical practice guideline
    • Kalkanis SN, Kondziolka D, Gaspar LE, et al: The role of surgical resection in the management of newly diagnosed brain metastases: a systematic review and evidence-based clinical practice guideline. J Neurooncol 96: 33-43, 2010.
    • (2010) J Neurooncol , vol.96 , pp. 33-43
    • Kalkanis, S.N.1    Kondziolka, D.2    Gaspar, L.E.3
  • 36
    • 75049083262 scopus 로고    scopus 로고
    • The role of emerging and investigational therapies for metastatic brain tumors: A systematic review and evidence-based clinical practice guideline of selected topics
    • Olson JJ, Paleologos NA, Gaspar LE, et al: The role of emerging and investigational therapies for metastatic brain tumors: a systematic review and evidence-based clinical practice guideline of selected topics. J Neurooncol 96: 115-142, 2010.
    • (2010) J Neurooncol , vol.96 , pp. 115-142
    • Olson, J.J.1    Paleologos, N.A.2    Gaspar, L.E.3
  • 37
    • 84869870044 scopus 로고    scopus 로고
    • Biology of brain metastases and novel targeted therapies: Time to translate the research
    • Fokas E, Steinbach JP and Rödel C: Biology of brain metastases and novel targeted therapies: time to translate the research. Biochim Biophys Acta 1835: 61-75, 2013.
    • (2013) Biochim Biophys Acta , vol.1835 , pp. 61-75
    • Fokas, E.1    Steinbach, J.P.2    Rödel, C.3
  • 38
    • 70450263474 scopus 로고    scopus 로고
    • Cellular elements of the blood-brain barrier
    • Correale J and Villa A: Cellular elements of the blood-brain barrier. Neurochem Res 34: 2067-2077, 2009.
    • (2009) Neurochem Res , vol.34 , pp. 2067-2077
    • Correale, J.1    Villa, A.2
  • 39
    • 0021972672 scopus 로고
    • Endothelial fenestral diaphragms: A quick-freeze, deep-etch study
    • Bearer EL and Orci L: Endothelial fenestral diaphragms: a quick-freeze, deep-etch study. J Cell Biol 100: 418-428, 1985.
    • (1985) J Cell Biol , vol.100 , pp. 418-428
    • Bearer, E.L.1    Orci, L.2
  • 40
    • 0014481056 scopus 로고
    • Junctions between intimately apposed cell membranes in the vertebrate brain
    • Brightman MW and Reese TS: Junctions between intimately apposed cell membranes in the vertebrate brain. J Cell Biol 40: 648-677, 1969.
    • (1969) J Cell Biol , vol.40 , pp. 648-677
    • Brightman, M.W.1    Reese, T.S.2
  • 41
    • 0026581496 scopus 로고
    • Structural domains of the tight junctional intramembrane fibrils
    • Lane NJ, Reese TS and Kachar B: Structural domains of the tight junctional intramembrane fibrils. Tissue Cell 24: 291-300, 1992.
    • (1992) Tissue Cell , vol.24 , pp. 291-300
    • Lane, N.J.1    Reese, T.S.2    Kachar, B.3
  • 42
    • 0027394873 scopus 로고
    • Transcytosis of protein through the mammalian cerebral epithelium and endothelium. II. Adsorptive transcytosis of WGA-HRP and the blood-brain and brain-blood barriers
    • Villegas JC and Broadwell RD: Transcytosis of protein through the mammalian cerebral epithelium and endothelium. II. Adsorptive transcytosis of WGA-HRP and the blood-brain and brain-blood barriers. J Neurocytol 22: 67-80, 1993.
    • (1993) J Neurocytol , vol.22 , pp. 67-80
    • Villegas, J.C.1    Broadwell, R.D.2
  • 44
    • 0035129369 scopus 로고    scopus 로고
    • Heterogeneity in expression and subcellular localization of claudins 2, 3, 4, and 5 in the rat liver, pancreas, and gut
    • Rahner C, Mitic LL and Anderson JM: Heterogeneity in expression and subcellular localization of claudins 2, 3, 4, and 5 in the rat liver, pancreas, and gut. Gastroenterology 120: 411-422, 2001.
    • (2001) Gastroenterology , vol.120 , pp. 411-422
    • Rahner, C.1    Mitic, L.L.2    Anderson, J.M.3
  • 45
    • 43149111598 scopus 로고    scopus 로고
    • Claudin-5 is restricted to the tight junction region of uterine epithelial cells in the uterus of pregnant/gravid squamate reptiles
    • Biazik JM, Thompson MB and Murphy CR: Claudin-5 is restricted to the tight junction region of uterine epithelial cells in the uterus of pregnant/gravid squamate reptiles. Anat Rec (Hoboken) 291: 547-556, 2008.
    • (2008) Anat Rec (Hoboken) , vol.291 , pp. 547-556
    • Biazik, J.M.1    Thompson, M.B.2    Murphy, C.R.3
  • 46
    • 22144441209 scopus 로고    scopus 로고
    • Contribution of claudin-5 to barrier properties in tight junctions of epithelial cells
    • Amasheh S, Schmidt T, Mahn M, et al: Contribution of claudin-5 to barrier properties in tight junctions of epithelial cells. Cell Tissue Res 321: 89-96, 2005.
    • (2005) Cell Tissue Res , vol.321 , pp. 89-96
    • Amasheh, S.1    Schmidt, T.2    Mahn, M.3
  • 47
    • 84872159164 scopus 로고    scopus 로고
    • Quantitative targeted absolute proteomic analysis of transporters, receptors and junction proteins for validation of human cerebral microvascular endothelial cell line hCMEC/D3 as a human blood-brain barrier model
    • Ohtsuki S, Ikeda C, Uchida Y, et al: Quantitative targeted absolute proteomic analysis of transporters, receptors and junction proteins for validation of human cerebral microvascular endothelial cell line hCMEC/D3 as a human blood-brain barrier model. Mol Pharm 10: 289-296, 2013.
    • (2013) Mol Pharm , vol.10 , pp. 289-296
    • Ohtsuki, S.1    Ikeda, C.2    Uchida, Y.3
  • 48
    • 4544311402 scopus 로고    scopus 로고
    • Selective decrease in paracellular conductance of tight junctions: Role of the first extracellular domain of claudin-5
    • Wen H, Watry DD, Marcondes MC and Fox HS: Selective decrease in paracellular conductance of tight junctions: role of the first extracellular domain of claudin-5. Mol Cell Biol 24: 8408-8417, 2004.
    • (2004) Mol Cell Biol , vol.24 , pp. 8408-8417
    • Wen, H.1    Watry, D.D.2    Marcondes, M.C.3    Fox, H.S.4
  • 49
    • 82255163077 scopus 로고    scopus 로고
    • Elucidating the principles of the molecular organization of heteropolymeric tight junction strands
    • Piontek J, Fritzsche S, Cording J, et al: Elucidating the principles of the molecular organization of heteropolymeric tight junction strands. Cell Mol Life Sci 68: 3903-3918, 2011.
    • (2011) Cell Mol Life Sci , vol.68 , pp. 3903-3918
    • Piontek, J.1    Fritzsche, S.2    Cording, J.3
  • 50
    • 84874387050 scopus 로고    scopus 로고
    • Claudin-5 controls intercellular barriers of human dermal microvascular but not human umbilical vein endothelial cells
    • Kluger MS, Clark PR, Tellides G, Gerke V and Pober JS: Claudin-5 controls intercellular barriers of human dermal microvascular but not human umbilical vein endothelial cells. Arterioscler Thromb Vasc Biol 33: 489-500, 2013.
    • (2013) Arterioscler Thromb Vasc Biol , vol.33 , pp. 489-500
    • Kluger, M.S.1    Clark, P.R.2    Tellides, G.3    Gerke, V.4    Pober, J.S.5
  • 51
    • 79960741978 scopus 로고    scopus 로고
    • MMP-mediated disruption of claudin-5 in the blood-brain barrier of rat brain after cerebral ischemia
    • Yang Y and Rosenberg GA: MMP-mediated disruption of claudin-5 in the blood-brain barrier of rat brain after cerebral ischemia. Methods Mol Biol 762: 333-345, 2011.
    • (2011) Methods Mol Biol , vol.762 , pp. 333-345
    • Yang, Y.1    Rosenberg, G.A.2
  • 52
    • 84865300131 scopus 로고    scopus 로고
    • Activation of AMP-activated protein kinase alleviates high-glucose-induced dysfunction of brain microvascular endothelial cell tight-junction dynamics
    • Liu C, Wu J and Zou MH: Activation of AMP-activated protein kinase alleviates high-glucose-induced dysfunction of brain microvascular endothelial cell tight-junction dynamics. Free Radic Biol Med 53: 1213-1221, 2012.
    • (2012) Free Radic Biol Med , vol.53 , pp. 1213-1221
    • Liu, C.1    Wu, J.2    Zou, M.H.3
  • 53
    • 78951486139 scopus 로고    scopus 로고
    • Assessments of tight junction proteins occludin, claudin 5 and scaffold proteins ZO1 and ZO2 in endothelial cells of the rat blood-brain barrier: Cellular responses to neurotoxicants malathion and lead acetate
    • Balbuena P, Li W and Ehrich M: Assessments of tight junction proteins occludin, claudin 5 and scaffold proteins ZO1 and ZO2 in endothelial cells of the rat blood-brain barrier: cellular responses to neurotoxicants malathion and lead acetate. Neurotoxicology 32: 58-67, 2011.
    • (2011) Neurotoxicology , vol.32 , pp. 58-67
    • Balbuena, P.1    Li, W.2    Ehrich, M.3
  • 54
    • 78649646826 scopus 로고    scopus 로고
    • Paracellular tightness and claudin-5 expression is increased in the BCEC/astrocyte blood-brain barrier model by increasing media buffer capacity during growth
    • Helms HC, Waagepetersen HS, Nielsen CU and Brodin B: Paracellular tightness and claudin-5 expression is increased in the BCEC/astrocyte blood-brain barrier model by increasing media buffer capacity during growth. AAPS J 12: 759-770, 2010.
    • (2010) AAPS J , vol.12 , pp. 759-770
    • Helms, H.C.1    Waagepetersen, H.S.2    Nielsen, C.U.3    Brodin, B.4
  • 55
    • 0142026252 scopus 로고    scopus 로고
    • Cyclic AMP induces phosphorylation of claudin-5 immunoprecipitates and expression of claudin-5 gene in blood-brain-barrier endothelial cells via protein kinase A-dependent and-independent pathways
    • Ishizaki T, Chiba H, Kojima T, et al: Cyclic AMP induces phosphorylation of claudin-5 immunoprecipitates and expression of claudin-5 gene in blood-brain-barrier endothelial cells via protein kinase A-dependent and-independent pathways. Exp Cell Res 290: 275-288, 2003.
    • (2003) Exp Cell Res , vol.290 , pp. 275-288
    • Ishizaki, T.1    Chiba, H.2    Kojima, T.3
  • 56
    • 4644271738 scopus 로고    scopus 로고
    • Thr(207) of claudin-5 is involved in size-selective loosening of the endothelial barrier by cyclic AMP
    • Soma T, Chiba H, Kato-Mori Y, et al: Thr(207) of claudin-5 is involved in size-selective loosening of the endothelial barrier by cyclic AMP. Exp Cell Res 300: 202-212, 2004.
    • (2004) Exp Cell Res , vol.300 , pp. 202-212
    • Soma, T.1    Chiba, H.2    Kato-Mori, Y.3
  • 57
    • 84857468365 scopus 로고    scopus 로고
    • ETS-related gene (ERG) controls endothelial cell permeability via transcriptional regulation of the claudin 5 (CLDN5) gene
    • Yuan L, Le Bras A, Sacharidou A, et al: ETS-related gene (ERG) controls endothelial cell permeability via transcriptional regulation of the claudin 5 (CLDN5) gene. J Biol Chem 287: 6582-6591, 2012.
    • (2012) J Biol Chem , vol.287 , pp. 6582-6591
    • Yuan, L.1    Le Bras, A.2    Sacharidou, A.3
  • 58
    • 79951676935 scopus 로고    scopus 로고
    • Tyrosine phosphorylation of VE-cadherin and claudin-5 is associated with TGF-β1-induced permeability of centrally derived vascular endothelium
    • Shen W, Li S, Chung SH, et al: Tyrosine phosphorylation of VE-cadherin and claudin-5 is associated with TGF-β1-induced permeability of centrally derived vascular endothelium. Eur J Cell Biol 90: 323-332, 2011.
    • (2011) Eur J Cell Biol , vol.90 , pp. 323-332
    • Shen, W.1    Li, S.2    Chung, S.H.3
  • 59
    • 84856373406 scopus 로고    scopus 로고
    • Pericyte-derived glial cell line-derived neurotrophic factor increase the expression of claudin-5 in the blood-brain barrier and the blood-nerve barrier
    • Shimizu F, Sano Y, Saito K, et al: Pericyte-derived glial cell line-derived neurotrophic factor increase the expression of claudin-5 in the blood-brain barrier and the blood-nerve barrier. Neurochem Res 37: 401-409, 2012.
    • (2012) Neurochem Res , vol.37 , pp. 401-409
    • Shimizu, F.1    Sano, Y.2    Saito, K.3
  • 60
    • 79960725414 scopus 로고    scopus 로고
    • HIV-1-induced alterations of claudin-5 expression at the blood-brain barrier level
    • András IE and Toborek M: HIV-1-induced alterations of claudin-5 expression at the blood-brain barrier level. Methods Mol Biol 762: 355-370, 2011.
    • (2011) Methods Mol Biol , vol.762 , pp. 355-370
    • András, I.E.1    Toborek, M.2
  • 61
    • 24944459847 scopus 로고    scopus 로고
    • Signaling mechanisms of HIV-1 Tat-induced alterations of claudin-5 expression in brain endothelial cells
    • András IE, Pu H, Tian J, et al: Signaling mechanisms of HIV-1 Tat-induced alterations of claudin-5 expression in brain endothelial cells. J Cereb Blood Flow Metab 25: 1159-1170, 2005.
    • (2005) J Cereb Blood Flow Metab , vol.25 , pp. 1159-1170
    • András, I.E.1    Pu, H.2    Tian, J.3
  • 62
    • 41149121644 scopus 로고    scopus 로고
    • Bradykinin increases blood-tumor barrier permeability by down-regulating the expression levels of ZO-1, occludin, and claudin-5 and rearranging actin cytoskeleton
    • Liu LB, Xue YX, Liu YH and Wang YB: Bradykinin increases blood-tumor barrier permeability by down-regulating the expression levels of ZO-1, occludin, and claudin-5 and rearranging actin cytoskeleton. J Neurosci Res 86: 1153-1168, 2008.
    • (2008) J Neurosci Res , vol.86 , pp. 1153-1168
    • Liu, L.B.1    Xue, Y.X.2    Liu, Y.H.3    Wang, Y.B.4
  • 63
    • 80053560038 scopus 로고    scopus 로고
    • Interendothelial claudin-5 expression depends on cerebral endothelial cell-matrix adhesion by β(1)-integrins
    • Osada T, Gu YH, Kanazawa M, et al: Interendothelial claudin-5 expression depends on cerebral endothelial cell-matrix adhesion by β(1)-integrins. J Cereb Blood Flow Metab 31: 1972-1985, 2011.
    • (2011) J Cereb Blood Flow Metab , vol.31 , pp. 1972-1985
    • Osada, T.1    Gu, Y.H.2    Kanazawa, M.3
  • 64
    • 84866001368 scopus 로고    scopus 로고
    • Sodium caprate transiently opens claudin-5-containing barriers at tight junctions of epithelial and endothelial cells
    • Del Vecchio G, Tscheik C, Tenz K, et al: Sodium caprate transiently opens claudin-5-containing barriers at tight junctions of epithelial and endothelial cells. Mol Pharm 9: 2523-2533, 2012.
    • (2012) Mol Pharm , vol.9 , pp. 2523-2533
    • Del Vecchio, G.1    Tscheik, C.2    Tenz, K.3
  • 65
    • 0033938847 scopus 로고    scopus 로고
    • Claudin-1 and claudin-5 expression and tight junction morphology are altered in blood vessels of human glioblastoma multiforme
    • Liebner S, Fischmann A, Rascher G, et al: Claudin-1 and claudin-5 expression and tight junction morphology are altered in blood vessels of human glioblastoma multiforme. Acta Neuropathol 100: 323-331, 2000.
    • (2000) Acta Neuropathol , vol.100 , pp. 323-331
    • Liebner, S.1    Fischmann, A.2    Rascher, G.3
  • 66
    • 77954908749 scopus 로고    scopus 로고
    • Independent histological risk factors for lymph node metastasis of superficial esophageal squamous cell carcinoma; Implication of claudin-5 immunohistochemistry for expanding the indications of endoscopic resection
    • Chiba T, Kawachi H, Kawano T, et al: Independent histological risk factors for lymph node metastasis of superficial esophageal squamous cell carcinoma; implication of claudin-5 immunohistochemistry for expanding the indications of endoscopic resection. Dis Esophagus 23: 398-407, 2010.
    • (2010) Dis Esophagus , vol.23 , pp. 398-407
    • Chiba, T.1    Kawachi, H.2    Kawano, T.3
  • 67
    • 0035958937 scopus 로고    scopus 로고
    • Claudin promotes activation of pro-matrix metalloproteinase-2 mediated by membrane-type matrix metalloproteinases
    • Miyamori H, Takino T, Kobayashi Y, et al: Claudin promotes activation of pro-matrix metalloproteinase-2 mediated by membrane-type matrix metalloproteinases. J Biol Chem 276: 28204-28211, 2001.
    • (2001) J Biol Chem , vol.276 , pp. 28204-28211
    • Miyamori, H.1    Takino, T.2    Kobayashi, Y.3
  • 68
    • 67650511699 scopus 로고    scopus 로고
    • Caveolae-mediated internalization of occludin and claudin-5 during CCL2-induced tight junction remodeling in brain endothelial cells
    • Stamatovic SM, Keep RF, Wang MM, Jankovic I and Andjelkovic AV: Caveolae-mediated internalization of occludin and claudin-5 during CCL2-induced tight junction remodeling in brain endothelial cells. J Biol Chem 284: 19053-19066, 2009.
    • (2009) J Biol Chem , vol.284 , pp. 19053-19066
    • Stamatovic, S.M.1    Keep, R.F.2    Wang, M.M.3    Jankovic, I.4    Andjelkovic, A.V.5
  • 69
    • 79960738413 scopus 로고    scopus 로고
    • Tracing the endocytosis of claudin-5 in brain endothelial cells
    • Stamatovic SM, Keep RF and Andjelkovic AV: Tracing the endocytosis of claudin-5 in brain endothelial cells. Methods Mol Biol 762: 303-320, 2011.
    • (2011) Methods Mol Biol , vol.762 , pp. 303-320
    • Stamatovic, S.M.1    Keep, R.F.2    Andjelkovic, A.V.3
  • 70
    • 84860514579 scopus 로고    scopus 로고
    • Claudin-5 is involved in breast cancer cell motility through the N-WASP and ROCK signalling pathways
    • Escudero-Esparza A, Jiang WG and Martin TA: Claudin-5 is involved in breast cancer cell motility through the N-WASP and ROCK signalling pathways. J Exp Clin Cancer Res 31: 43, 2012.
    • (2012) J Exp Clin Cancer Res , vol.31 , pp. 43
    • Escudero-Esparza, A.1    Jiang, W.G.2    Martin, T.A.3
  • 71
    • 39549112926 scopus 로고    scopus 로고
    • Phosphorylation of claudin-5 and occludin by rho kinase in brain endothelial cells
    • Yamamoto M, Ramirez SH, Sato S, et al: Phosphorylation of claudin-5 and occludin by rho kinase in brain endothelial cells. Am J Pathol 172: 521-533, 2008.
    • (2008) Am J Pathol , vol.172 , pp. 521-533
    • Yamamoto, M.1    Ramirez, S.H.2    Sato, S.3
  • 72
    • 33745094734 scopus 로고    scopus 로고
    • Rho-mediated regulation of tight junctions during monocyte migration across the blood-brain barrier in HIV-1 encephalitis (HIVE)
    • Persidsky Y, Heilman D, Haorah J, et al: Rho-mediated regulation of tight junctions during monocyte migration across the blood-brain barrier in HIV-1 encephalitis (HIVE). Blood 107: 4770-4780, 2006.
    • (2006) Blood , vol.107 , pp. 4770-4780
    • Persidsky, Y.1    Heilman, D.2    Haorah, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.