메뉴 건너뛰기




Volumn 106, Issue 2, 2014, Pages 45-56

Regulation of with-no-lysine kinase signaling by Kelch-like proteins

Author keywords

Hypertension; Kidney; Kinases; Membrane transport; Ubiquitin

Indexed keywords

CULLIN3 PROTEIN; KELCH LIKE 3 PROTEIN; OXIDATIVE STRESS RESPONSIVE GENE 1; PROTEIN KINASE WNK1; PROTEIN KINASE WNK4; PROTEIN SERINE THREONINE KINASE; STE20 RELATED PROLINE ALANINE RICH KINASE; UNCLASSIFIED DRUG; WITH NO LYSINE KINASE;

EID: 84893815155     PISSN: 02484900     EISSN: 1768322X     Source Type: Journal    
DOI: 10.1111/boc.201300069     Document Type: Article
Times cited : (29)

References (86)
  • 1
    • 0033961690 scopus 로고    scopus 로고
    • The kelch repeat superfamily of proteins: propellers of cell function
    • Adams, J., Kelso, R. and Cooley, L. (2000) The kelch repeat superfamily of proteins: propellers of cell function. Trends Cell Biol. 10, 17-24
    • (2000) Trends Cell Biol. , vol.10 , pp. 17-24
    • Adams, J.1    Kelso, R.2    Cooley, L.3
  • 5
    • 33745076253 scopus 로고    scopus 로고
    • WNK4 kinase regulates surface expression of the human sodium chloride cotransporter in mammalian cells
    • Cai, H., Cebotaru, V., Wang, Y.H., Zhang, X.M., Cebotaru, L., Guggino, S.E. and Guggino, W.B. (2006) WNK4 kinase regulates surface expression of the human sodium chloride cotransporter in mammalian cells. Kidney Int. 69, 2162-2170
    • (2006) Kidney Int. , vol.69 , pp. 2162-2170
    • Cai, H.1    Cebotaru, V.2    Wang, Y.H.3    Zhang, X.M.4    Cebotaru, L.5    Guggino, S.E.6    Guggino, W.B.7
  • 7
    • 84865419996 scopus 로고    scopus 로고
    • Mechanisms of sodium-chloride cotransporter modulation by angiotensin II
    • Castaneda-Bueno, M. and Gamba, G. (2012) Mechanisms of sodium-chloride cotransporter modulation by angiotensin II. Curr. Opin. Nephrol. Hypertens. 21, 516-522
    • (2012) Curr. Opin. Nephrol. Hypertens. , vol.21 , pp. 516-522
    • Castaneda-Bueno, M.1    Gamba, G.2
  • 9
    • 79955534755 scopus 로고    scopus 로고
    • Phenotypes of pseudohypoaldosteronism type II caused by the WNK4 D561A missense mutation are dependent on the WNK-OSR1/SPAK kinase cascade
    • Chiga, M., Rafiqi, F.H., Alessi, D.R., Sohara, E., Ohta, A., Rai, T., Sasaki, S. and Uchida, S. (2011) Phenotypes of pseudohypoaldosteronism type II caused by the WNK4 D561A missense mutation are dependent on the WNK-OSR1/SPAK kinase cascade. J. Cell Sci. 124, 1391-1395
    • (2011) J. Cell Sci. , vol.124 , pp. 1391-1395
    • Chiga, M.1    Rafiqi, F.H.2    Alessi, D.R.3    Sohara, E.4    Ohta, A.5    Rai, T.6    Sasaki, S.7    Uchida, S.8
  • 10
    • 56549094967 scopus 로고    scopus 로고
    • Dietary salt regulates the phosphorylation of OSR1/SPAK kinases and the sodium chloride cotransporter through aldosterone
    • Chiga, M., Rai, T., Yang, S.S., Ohta, A., Takizawa, T., Sasaki, S. and Uchida, S. (2008) Dietary salt regulates the phosphorylation of OSR1/SPAK kinases and the sodium chloride cotransporter through aldosterone. Kidney Int. 74, 1403-1409
    • (2008) Kidney Int. , vol.74 , pp. 1403-1409
    • Chiga, M.1    Rai, T.2    Yang, S.S.3    Ohta, A.4    Takizawa, T.5    Sasaki, S.6    Uchida, S.7
  • 14
    • 0344197746 scopus 로고    scopus 로고
    • Multiple promoters in the WNK1 gene: one controls expression of a kidney-specific kinase-defective isoform
    • Delaloy, C., Lu, J., Houot, A.M., Disse-Nicodeme, S., Gasc, J.M., Corvol, P. and Jeunemaitre, X. (2003) Multiple promoters in the WNK1 gene: one controls expression of a kidney-specific kinase-defective isoform. Mol. Cell Biol. 23, 9208-9221
    • (2003) Mol. Cell Biol. , vol.23 , pp. 9208-9221
    • Delaloy, C.1    Lu, J.2    Houot, A.M.3    Disse-Nicodeme, S.4    Gasc, J.M.5    Corvol, P.6    Jeunemaitre, X.7
  • 16
    • 0042847432 scopus 로고    scopus 로고
    • PASK (proline-alanine-rich STE20-related kinase), a regulatory kinase of the Na-K-Cl cotransporter (NKCC1)
    • Dowd, B.F. and Forbush, B. (2003) PASK (proline-alanine-rich STE20-related kinase), a regulatory kinase of the Na-K-Cl cotransporter (NKCC1). J. Biol. Chem. 278, 27347-27353
    • (2003) J. Biol. Chem. , vol.278 , pp. 27347-27353
    • Dowd, B.F.1    Forbush, B.2
  • 17
    • 0037020095 scopus 로고    scopus 로고
    • Activation of the Na-K-Cl cotransporter NKCC1 detected with a phospho-specific antibody
    • Flemmer, A.W., Gimenez, I., Dowd, B.F., Darman, R.B. and Forbush, B. (2002) Activation of the Na-K-Cl cotransporter NKCC1 detected with a phospho-specific antibody. J. Biol. Chem. 277, 37551-37558
    • (2002) J. Biol. Chem. , vol.277 , pp. 37551-37558
    • Flemmer, A.W.1    Gimenez, I.2    Dowd, B.F.3    Darman, R.B.4    Forbush, B.5
  • 19
    • 33744819162 scopus 로고    scopus 로고
    • TRPV4: a new target for the hypertension-related kinases WNK1 and WNK4
    • Gamba, G. (2006) TRPV4: a new target for the hypertension-related kinases WNK1 and WNK4. Am. J. Physiol. Renal. Physiol. 290, F1303-F1304
    • (2006) Am. J. Physiol. Renal. Physiol. , vol.290
    • Gamba, G.1
  • 21
    • 0023039605 scopus 로고
    • Syndrome of hypertension and hyperkalemia with normal glomerular filtration rate
    • Gordon, R.D. (1986) Syndrome of hypertension and hyperkalemia with normal glomerular filtration rate. Hypertension 8, 93-102
    • (1986) Hypertension , vol.8 , pp. 93-102
    • Gordon, R.D.1
  • 25
    • 33749440293 scopus 로고    scopus 로고
    • WNK protein kinases modulate cellular Cl- flux by altering the phosphorylation state of the Na-K-Cl and K-Cl cotransporters
    • Kahle, K.T., Rinehart, J., Ring, A., Gimenez, I., Gamba, G., Hebert, S.C. and Lifton, R.P. (2006) WNK protein kinases modulate cellular Cl- flux by altering the phosphorylation state of the Na-K-Cl and K-Cl cotransporters. Physiology (Bethesda) 21, 326-335
    • (2006) Physiology (Bethesda) , vol.21 , pp. 326-335
    • Kahle, K.T.1    Rinehart, J.2    Ring, A.3    Gimenez, I.4    Gamba, G.5    Hebert, S.C.6    Lifton, R.P.7
  • 27
    • 80052981806 scopus 로고    scopus 로고
    • Ubiquitin ligase activity of Cul3-KLHL7 protein is attenuated by autosomal dominant retinitis pigmentosa causative mutation
    • Kigoshi, Y., Tsuruta, F. and Chiba, T. (2011) Ubiquitin ligase activity of Cul3-KLHL7 protein is attenuated by autosomal dominant retinitis pigmentosa causative mutation. J. Biol. Chem. 286, 33613-33621
    • (2011) J. Biol. Chem. , vol.286 , pp. 33613-33621
    • Kigoshi, Y.1    Tsuruta, F.2    Chiba, T.3
  • 28
    • 84866547191 scopus 로고    scopus 로고
    • Enhanced phosphorylation of Na(+)-Cl- co-transporter in experimental metabolic syndrome: role of insulin
    • Komers, R., Rogers, S., Oyama, T.T., Xu, B., Yang, C.L., McCormick, J. and Ellison, D.H. (2012) Enhanced phosphorylation of Na(+)-Cl- co-transporter in experimental metabolic syndrome: role of insulin. Clin. Sci. (Lond.) 123, 635-647
    • (2012) Clin. Sci. (Lond.) , vol.123 , pp. 635-647
    • Komers, R.1    Rogers, S.2    Oyama, T.T.3    Xu, B.4    Yang, C.L.5    McCormick, J.6    Ellison, D.H.7
  • 31
    • 77952580741 scopus 로고    scopus 로고
    • The Cullin 3 substrate adaptor KLHL20 mediates DAPK ubiquitination to control interferon responses
    • Lee, Y.R., Yuan, W.C., Ho, H.C., Chen, C.H., Shih, H.M. and Chen, R.H. (2010) The Cullin 3 substrate adaptor KLHL20 mediates DAPK ubiquitination to control interferon responses. EMBO J. 29, 1748-1761
    • (2010) EMBO J. , vol.29 , pp. 1748-1761
    • Lee, Y.R.1    Yuan, W.C.2    Ho, H.C.3    Chen, C.H.4    Shih, H.M.5    Chen, R.H.6
  • 32
    • 79959485783 scopus 로고    scopus 로고
    • PDZ-RhoGEF ubiquitination by Cullin3-KLHL20 controls neurotrophin-induced neurite outgrowth
    • Lin, M.Y., Lin, Y.M., Kao, T.C., Chuang, H.H. and Chen, R.H. (2011) PDZ-RhoGEF ubiquitination by Cullin3-KLHL20 controls neurotrophin-induced neurite outgrowth. J. Cell Biol. 193, 985-994
    • (2011) J. Cell Biol. , vol.193 , pp. 985-994
    • Lin, M.Y.1    Lin, Y.M.2    Kao, T.C.3    Chuang, H.H.4    Chen, R.H.5
  • 34
    • 78751654853 scopus 로고    scopus 로고
    • The WNKs: atypical protein kinases with pleiotropic actions
    • McCormick, J.A. and Ellison, D.H. (2011) The WNKs: atypical protein kinases with pleiotropic actions. Physiol. Rev. 91, 177-219
    • (2011) Physiol. Rev. , vol.91 , pp. 177-219
    • McCormick, J.A.1    Ellison, D.H.2
  • 36
    • 30044442784 scopus 로고    scopus 로고
    • WNK1 regulates phosphorylation of cation-chloride-coupled cotransporters via the STE20-related kinases, SPAK and OSR1
    • Moriguchi, T., Urushiyama, S., Hisamoto, N., Iemura, S., Uchida, S., Natsume, T., Matsumoto, K. and Shibuya, H. (2005) WNK1 regulates phosphorylation of cation-chloride-coupled cotransporters via the STE20-related kinases, SPAK and OSR1. J. Biol. Chem. 280, 42685-42693
    • (2005) J. Biol. Chem. , vol.280 , pp. 42685-42693
    • Moriguchi, T.1    Urushiyama, S.2    Hisamoto, N.3    Iemura, S.4    Uchida, S.5    Natsume, T.6    Matsumoto, K.7    Shibuya, H.8
  • 39
    • 84866543932 scopus 로고    scopus 로고
    • Phosphatidylinositol 3-kinase/Akt signaling pathway activates the WNK-OSR1/SPAK-NCC phosphorylation cascade in hyperinsulinemic db/db mice
    • Nishida, H., Sohara, E., Nomura, N., Chiga, M., Alessi, D.R., Rai, T., Sasaki, S. and Uchida, S. (2012) Phosphatidylinositol 3-kinase/Akt signaling pathway activates the WNK-OSR1/SPAK-NCC phosphorylation cascade in hyperinsulinemic db/db mice. Hypertension 60, 981-990
    • (2012) Hypertension , vol.60 , pp. 981-990
    • Nishida, H.1    Sohara, E.2    Nomura, N.3    Chiga, M.4    Alessi, D.R.5    Rai, T.6    Sasaki, S.7    Uchida, S.8
  • 40
    • 0141455346 scopus 로고    scopus 로고
    • WNK1, a gene within a novel blood pressure control pathway, tissue-specifically generates radically different isoforms with and without a kinase domain
    • O'Reilly, M., Marshall, E., Speirs, H.J. and Brown, R.W. (2003) WNK1, a gene within a novel blood pressure control pathway, tissue-specifically generates radically different isoforms with and without a kinase domain. J. Am. Soc. Nephrol. 14, 2447-2456
    • (2003) J. Am. Soc. Nephrol. , vol.14 , pp. 2447-2456
    • O'Reilly, M.1    Marshall, E.2    Speirs, H.J.3    Brown, R.W.4
  • 41
    • 70349581037 scopus 로고    scopus 로고
    • Targeted disruption of the Wnk4 gene decreases phosphorylation of Na-Cl cotransporter, increases Na excretion and lowers blood pressure
    • Ohta, A., Rai, T., Yui, N., Chiga, M., Yang, S.S., Lin, S.H., Sohara, E., Sasaki, S. and Uchida, S. (2009) Targeted disruption of the Wnk4 gene decreases phosphorylation of Na-Cl cotransporter, increases Na excretion and lowers blood pressure. Hum. Mol. Genet. 18, 3978-3986
    • (2009) Hum. Mol. Genet. , vol.18 , pp. 3978-3986
    • Ohta, A.1    Rai, T.2    Yui, N.3    Chiga, M.4    Yang, S.S.5    Lin, S.H.6    Sohara, E.7    Sasaki, S.8    Uchida, S.9
  • 42
    • 84875158737 scopus 로고    scopus 로고
    • The CUL3-KLHL3 E3 ligase complex mutated in Gordon's hypertension syndrome interacts with and ubiquitylates WNK isoforms: disease-causing mutations in KLHL3 and WNK4 disrupt interaction
    • Ohta, A., Schumacher, F.R., Mehellou, Y., Johnson, C., Knebel, A., Macartney, T.J., Wood, N.T., Alessi, D.R. and Kurz, T. (2013) The CUL3-KLHL3 E3 ligase complex mutated in Gordon's hypertension syndrome interacts with and ubiquitylates WNK isoforms: disease-causing mutations in KLHL3 and WNK4 disrupt interaction. Biochem. J. 451, 111-122
    • (2013) Biochem. J. , vol.451 , pp. 111-122
    • Ohta, A.1    Schumacher, F.R.2    Mehellou, Y.3    Johnson, C.4    Knebel, A.5    Macartney, T.J.6    Wood, N.T.7    Alessi, D.R.8    Kurz, T.9
  • 43
    • 84964677935 scopus 로고    scopus 로고
    • A minor role of WNK3 in regulating phosphorylation of renal NKCC2 and NCC co-transporters in vivo
    • Oi, K., Sohara, E., Rai, T., Misawa, M., Chiga, M., Alessi, D., Sasaki, S. and Uchida, S. (2012) A minor role of WNK3 in regulating phosphorylation of renal NKCC2 and NCC co-transporters in vivo. Biology Open 1, 120-127
    • (2012) Biology Open , vol.1 , pp. 120-127
    • Oi, K.1    Sohara, E.2    Rai, T.3    Misawa, M.4    Chiga, M.5    Alessi, D.6    Sasaki, S.7    Uchida, S.8
  • 44
    • 84881051118 scopus 로고    scopus 로고
    • CUL3 gene analysis enables early intervention for pediatric pseudohypoaldosteronism type II in infancy
    • Osawa, M., Ogura, Y., Isobe, K., Uchida, S., Nonoyama, S. and Kawaguchi, H. (2013) CUL3 gene analysis enables early intervention for pediatric pseudohypoaldosteronism type II in infancy. Pediatr. Nephrol. 28, 1881-1884
    • (2013) Pediatr. Nephrol. , vol.28 , pp. 1881-1884
    • Osawa, M.1    Ogura, Y.2    Isobe, K.3    Uchida, S.4    Nonoyama, S.5    Kawaguchi, H.6
  • 46
    • 77954243057 scopus 로고    scopus 로고
    • Vasopressin induces phosphorylation of the thiazide-sensitive sodium chloride cotransporter in the distal convoluted tubule
    • Pedersen, N.B., Hofmeister, M.V., Rosenbaek, L.L., Nielsen, J. and Fenton, R.A. (2010) Vasopressin induces phosphorylation of the thiazide-sensitive sodium chloride cotransporter in the distal convoluted tubule. Kidney Int. 78, 160-169
    • (2010) Kidney Int. , vol.78 , pp. 160-169
    • Pedersen, N.B.1    Hofmeister, M.V.2    Rosenbaek, L.L.3    Nielsen, J.4    Fenton, R.A.5
  • 47
    • 0346101747 scopus 로고    scopus 로고
    • Characterization of the interaction of the stress kinase SPAK with the Na+-K+-2Cl- cotransporter in the nervous system: evidence for a scaffolding role of the kinase
    • Piechotta, K., Garbarini, N., England, R. and Delpire, E. (2003) Characterization of the interaction of the stress kinase SPAK with the Na+-K+-2Cl- cotransporter in the nervous system: evidence for a scaffolding role of the kinase. J. Biol. Chem. 278, 52848-52856
    • (2003) J. Biol. Chem. , vol.278 , pp. 52848-52856
    • Piechotta, K.1    Garbarini, N.2    England, R.3    Delpire, E.4
  • 48
    • 0037184942 scopus 로고    scopus 로고
    • Cation chloride cotransporters interact with the stress-related kinases Ste20-related proline-alanine-rich kinase (SPAK) and oxidative stress response 1 (OSR1)
    • Piechotta, K., Lu, J. and Delpire, E. (2002) Cation chloride cotransporters interact with the stress-related kinases Ste20-related proline-alanine-rich kinase (SPAK) and oxidative stress response 1 (OSR1). J. Biol. Chem. 277, 50812-50819
    • (2002) J. Biol. Chem. , vol.277 , pp. 50812-50819
    • Piechotta, K.1    Lu, J.2    Delpire, E.3
  • 49
    • 2942606074 scopus 로고    scopus 로고
    • Molecular phylogeny of the kelch-repeat superfamily reveals an expansion of BTB/kelch proteins in animals
    • Prag, S. and Adams, J.C. (2003) Molecular phylogeny of the kelch-repeat superfamily reveals an expansion of BTB/kelch proteins in animals. BMC Bioinformatics 4, 42
    • (2003) BMC Bioinformatics , vol.4 , pp. 42
    • Prag, S.1    Adams, J.C.2
  • 50
    • 84871335612 scopus 로고    scopus 로고
    • Adenylyl cyclase 6 enhances NKCC2 expression and mediates vasopressin-induced phosphorylation of NKCC2 and NCC
    • Rieg, T., Tang, T., Uchida, S., Hammond, H.K., Fenton, R.A. and Vallon, V. (2013) Adenylyl cyclase 6 enhances NKCC2 expression and mediates vasopressin-induced phosphorylation of NKCC2 and NCC. Am. J. Pathol. 182, 96-106
    • (2013) Am. J. Pathol. , vol.182 , pp. 96-106
    • Rieg, T.1    Tang, T.2    Uchida, S.3    Hammond, H.K.4    Fenton, R.A.5    Vallon, V.6
  • 56
    • 84877340391 scopus 로고    scopus 로고
    • Kelch-like 3 and Cullin 3 regulate electrolyte homeostasis via ubiquitination and degradation of WNK4
    • Shibata, S., Zhang, J., Puthumana, J., Stone, K.L. and Lifton, R.P. (2013) Kelch-like 3 and Cullin 3 regulate electrolyte homeostasis via ubiquitination and degradation of WNK4. Proc. Natl. Acad. Sci. U. S. A. 110, 7838-7843
    • (2013) Proc. Natl. Acad. Sci. U. S. A. , vol.110 , pp. 7838-7843
    • Shibata, S.1    Zhang, J.2    Puthumana, J.3    Stone, K.L.4    Lifton, R.P.5
  • 62
    • 77949654325 scopus 로고    scopus 로고
    • Effect of angiotensin II on the WNK-OSR1/SPAK-NCC phosphorylation cascade in cultured mpkDCT cells and in vivo mouse kidney
    • Talati, G., Ohta, A., Rai, T., Sohara, E., Naito, S., Vandewalle, A., Sasaki, S. and Uchida, S. (2010) Effect of angiotensin II on the WNK-OSR1/SPAK-NCC phosphorylation cascade in cultured mpkDCT cells and in vivo mouse kidney. Biochem. Biophys. Res. Commun. 393, 844-848
    • (2010) Biochem. Biophys. Res. Commun. , vol.393 , pp. 844-848
    • Talati, G.1    Ohta, A.2    Rai, T.3    Sohara, E.4    Naito, S.5    Vandewalle, A.6    Sasaki, S.7    Uchida, S.8
  • 64
    • 69449100055 scopus 로고    scopus 로고
    • Expression and phosphorylation of the Na+-Cl- cotransporter NCC in vivo is regulated by dietary salt, potassium, and SGK1
    • Vallon, V., Schroth, J., Lang, F., Kuhl, D. and Uchida, S. (2009) Expression and phosphorylation of the Na+-Cl- cotransporter NCC in vivo is regulated by dietary salt, potassium, and SGK1. Am. J. Physiol. Renal. Physiol. 297, F704-712
    • (2009) Am. J. Physiol. Renal. Physiol. , vol.297
    • Vallon, V.1    Schroth, J.2    Lang, F.3    Kuhl, D.4    Uchida, S.5
  • 65
    • 85027955816 scopus 로고    scopus 로고
    • Angiotensin II induces phosphorylation of the thiazide-sensitive sodium chloride cotransporter independent of aldosterone
    • van der Lubbe, N., Lim, C.H., Fenton, R.A., Meima, M.E., Jan Danser, A.H., Zietse, R. and Hoorn, E.J. (2011) Angiotensin II induces phosphorylation of the thiazide-sensitive sodium chloride cotransporter independent of aldosterone. Kidney Int. 79, 66-76
    • (2011) Kidney Int. , vol.79 , pp. 66-76
    • van der Lubbe, N.1    Lim, C.H.2    Fenton, R.A.3    Meima, M.E.4    Jan Danser, A.H.5    Zietse, R.6    Hoorn, E.J.7
  • 67
    • 0035817725 scopus 로고    scopus 로고
    • WNK kinases, a novel protein kinase subfamily in multi-cellular organisms
    • Verissimo, F. and Jordan, P. (2001) WNK kinases, a novel protein kinase subfamily in multi-cellular organisms. Oncogene 20, 5562-5569
    • (2001) Oncogene , vol.20 , pp. 5562-5569
    • Verissimo, F.1    Jordan, P.2
  • 69
    • 26844532768 scopus 로고    scopus 로고
    • The WNK1 and WNK4 protein kinases that are mutated in Gordon's hypertension syndrome phosphorylate and activate SPAK and OSR1 protein kinases
    • Vitari, A.C., Deak, M., Morrice, N.A. and Alessi, D.R. (2005) The WNK1 and WNK4 protein kinases that are mutated in Gordon's hypertension syndrome phosphorylate and activate SPAK and OSR1 protein kinases. Biochem. J. 391, 17-24
    • (2005) Biochem. J. , vol.391 , pp. 17-24
    • Vitari, A.C.1    Deak, M.2    Morrice, N.A.3    Alessi, D.R.4
  • 73
    • 84878774970 scopus 로고    scopus 로고
    • Disease-causing mutations in KLHL3 impair its effect on WNK4 degradation
    • Wu, G. and Peng, J.B. (2013) Disease-causing mutations in KLHL3 impair its effect on WNK4 degradation. FEBS Lett. 587, 1717-1722
    • (2013) FEBS Lett. , vol.587 , pp. 1717-1722
    • Wu, G.1    Peng, J.B.2
  • 74
    • 0034595634 scopus 로고    scopus 로고
    • WNK1, a novel mammalian serine/threonine protein kinase lacking the catalytic lysine in subdomain II
    • Xu, B., English, J.M., Wilsbacher, J.L., Stippec, S., Goldsmith, E.J. and Cobb, M.H. (2000) WNK1, a novel mammalian serine/threonine protein kinase lacking the catalytic lysine in subdomain II. J. Biol. Chem. 275, 16795-16801
    • (2000) J. Biol. Chem. , vol.275 , pp. 16795-16801
    • Xu, B.1    English, J.M.2    Wilsbacher, J.L.3    Stippec, S.4    Goldsmith, E.J.5    Cobb, M.H.6
  • 75
    • 2242435334 scopus 로고    scopus 로고
    • Regulation of WNK1 by an autoinhibitory domain and autophosphorylation
    • Xu, B.E., Min, X., Stippec, S., Lee, B.H., Goldsmith, E.J. and Cobb, M.H. (2002) Regulation of WNK1 by an autoinhibitory domain and autophosphorylation. J. Biol. Chem. 277, 48456-48462
    • (2002) J. Biol. Chem. , vol.277 , pp. 48456-48462
    • Xu, B.E.1    Min, X.2    Stippec, S.3    Lee, B.H.4    Goldsmith, E.J.5    Cobb, M.H.6
  • 78
    • 0037382807 scopus 로고    scopus 로고
    • WNK kinases regulate thiazide-sensitive Na-Cl cotransport
    • Yang, C.L., Angell, J., Mitchell, R. and Ellison, D.H. (2003) WNK kinases regulate thiazide-sensitive Na-Cl cotransport. J. Clin. Invest. 111, 1039-1045
    • (2003) J. Clin. Invest. , vol.111 , pp. 1039-1045
    • Yang, C.L.1    Angell, J.2    Mitchell, R.3    Ellison, D.H.4
  • 80
    • 36048938340 scopus 로고    scopus 로고
    • The thiazide-sensitive Na-Cl cotransporter is regulated by a WNK kinase signaling complex
    • Yang, C.L., Zhu, X. and Ellison, D.H. (2007b) The thiazide-sensitive Na-Cl cotransporter is regulated by a WNK kinase signaling complex. J. Clin. Invest. 117, 3403-3411
    • (2007) J. Clin. Invest. , vol.117 , pp. 3403-3411
    • Yang, C.L.1    Zhu, X.2    Ellison, D.H.3
  • 81
    • 18244373189 scopus 로고    scopus 로고
    • Mechanisms of WNK1 and WNK4 interaction in the regulation of thiazide-sensitive NaCl cotransport
    • Yang, C.L., Zhu, X., Wang, Z., Subramanya, A.R. and Ellison, D.H. (2005) Mechanisms of WNK1 and WNK4 interaction in the regulation of thiazide-sensitive NaCl cotransport. J. Clin. Invest. 115, 1379-1387
    • (2005) J. Clin. Invest. , vol.115 , pp. 1379-1387
    • Yang, C.L.1    Zhu, X.2    Wang, Z.3    Subramanya, A.R.4    Ellison, D.H.5
  • 86
    • 0028110129 scopus 로고
    • The BTB domain, found primarily in zinc finger proteins, defines an evolutionarily conserved family that includes several developmentally regulated genes in Drosophila
    • Zollman, S., Godt, D., Prive, G.G., Couderc, J.L. and Laski, F.A. (1994) The BTB domain, found primarily in zinc finger proteins, defines an evolutionarily conserved family that includes several developmentally regulated genes in Drosophila. Proc. Natl. Acad. Sci. U. S. A. 91, 10717-10721
    • (1994) Proc. Natl. Acad. Sci. U. S. A. , vol.91 , pp. 10717-10721
    • Zollman, S.1    Godt, D.2    Prive, G.G.3    Couderc, J.L.4    Laski, F.A.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.