Synthesis and receptor binding studies of some new arylcarboxamide derivatives as sigma-1 ligands

Bioorganic and Medicinal Chemistry Letters

Volumn 24, Issue 4, 2014, Pages 1021-1025

  Zampieri, Daniele ^a   Laurini, Erik ^a   Vio, Luciano ^a   Golob, Samuel ^a   Fermeglia, Maurizio ^a   Pricl, Sabrina ^a   Mamolo, Maria Grazia ^a  

^a UNIVERSITY OF TRIESTE   (Italy)

Author keywords

Arylcarboxamide derivatives; Radioligand binding assays; Receptors

Indexed keywords

AMIDE; SIGMA 1 OPIATE RECEPTOR; SIGMA 2 OPIATE RECEPTOR;

ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; DRUG BINDING SITE; DRUG RECEPTOR BINDING; DRUG SYNTHESIS; NONHUMAN; PHARMACOPHORE; RAT;

ARYLCARBOXAMIDE DERIVATIVES; RADIOLIGAND BINDING ASSAYS; Σ-RECEPTORS;

AMIDES; ANIMALS; BINDING SITES; DOSE-RESPONSE RELATIONSHIP, DRUG; GUINEA PIGS; LIGANDS; MOLECULAR DYNAMICS SIMULATION; MOLECULAR STRUCTURE; RATS; RECEPTORS, SIGMA; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84893779615     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2014.01.032     Document Type: Article

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