Studies on the Enantiomers of RC-33 as Neuroprotective Agents: Isolation, Configurational Assignment, and Preliminary Biological Profile

Chirality

Volumn 25, Issue 11, 2013, Pages 814-822

  Rossi, Daniela ^a   Pedrali, Alice ^a   Marra, Annamaria ^a   Pignataro, Luca ^b   Schepmann, Dirk ^c   Wünsch, Bernhard ^c   Ye, Lian ^d   Leuner, Kristina ^d   Peviani, Marco ^a   Curti, Daniela ^a   Azzolina, Ornella ^a   Collina, Simona ^a  

^a UNIVERSITY OF PAVIA   (Italy)

^b UNIVERSITY OF MILAN   (Italy)

^c UNIVERSITY OF MÜNSTER   (Germany)

^d UNIVERSITY HOSPITAL ERLANGEN   (Germany)

Author keywords

1 receptor agonists; absolute configuration assignment; asymmetric hydrogenation; chemical correlation; enantioselective HPLC; neuroprotective agents

Indexed keywords

1 [3 (1,1' BIPHEN) 4 YL]BUTYL PIPERIDINE; NEUROPROTECTIVE AGENT; OPIATE AGONIST; PIPERIDINE DERIVATIVE; SIGMA 1 OPIATE RECEPTOR; UNCLASSIFIED DRUG;

ARTICLE; ASYMMETRIC SYNTHESIS; BIOLOGICAL ACTIVITY; CALCIUM TRANSPORT; CHIRALITY; CHROMATOGRAPHY; CONTROLLED STUDY; DRUG ISOLATION; ENANTIOMER; ENANTIOSELECTIVITY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IN VITRO STUDY; NEUROPROTECTION; OPTICS; PRIORITY JOURNAL; SEPARATION TECHNIQUE;

ABSOLUTE CONFIGURATION ASSIGNMENT; ASYMMETRIC HYDROGENATION; CHEMICAL CORRELATION; ENANTIOSELECTIVE HPLC; NEUROPROTECTIVE AGENTS; Σ1 RECEPTOR AGONISTS;

ANIMALS; BIPHENYL COMPOUNDS; BRAIN; GUINEA PIGS; NEUROPROTECTIVE AGENTS; PC12 CELLS; PIPERIDINES; RATS; RECEPTORS, SIGMA; STEREOISOMERISM;

EID: 84886639929     PISSN: 08990042     EISSN: 1520636X     Source Type: Journal    
DOI: 10.1002/chir.22223     Document Type: Article

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