Reciprocal regulation of Th1- and Th2-cytokine-producing T cells during clearance of parasitemia in Plasmodium falciparum malaria

Infection and Immunity

Volumn 66, Issue 12, 1998, Pages 6040-6044

  Winkler, Stefan ^a   Willheim, Martin ^b   Baier, Karin ^b   Schmid, Daniela ^a   Aichelburg, Alexander ^a   Graninger, Wolfgang ^a   Kremsner, Peter G ^a,c  

^a UNIVERSITY OF VIENNA   (Austria)

^b ALBERT SCHWEITZER HOSPITAL   (Gabon)

^c UNIVERSITY OF TÜBINGEN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 13; INTERLEUKIN 2; INTERLEUKIN 4; INTERLEUKIN 5; MONOCLONAL ANTIBODY; TUMOR NECROSIS FACTOR;

ADOLESCENT; ADULT; ARTICLE; CHILD; CLINICAL ARTICLE; CYTOKINE PRODUCTION; DISEASE COURSE; FEMALE; FLOW CYTOMETRY; HELPER CELL; HUMAN; IMMUNE RESPONSE; MALARIA; MALE; NONHUMAN; PARASITEMIA; PLASMODIUM FALCIPARUM; PRIORITY JOURNAL; REGULATORY MECHANISM; T LYMPHOCYTE SUBPOPULATION;

EID: 0031741637     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/iai.66.12.6040-6044.1998     Document Type: Article

References (34)

1. Clark, I. A., and N. H. Hunt. 1983. Evidence for reactive oxygen intermediates causing hemolysis and parasite death in malaria. Infect. Immun. 39:1-6.
2. D'Andrea, A., M. Aste-Amezaga, N. M. Valianta, X. Ma, M. Kubin, and G. Trinchieri. 1993. IL-10 inhibits human lymphocyte IFN-γ-production by suppressing IL-12 synthesis in accessory cells. J. Exp. Med. 178:1041-1048.
3. De Kossodo, S., C. Monso, P. Juillard, T. Velu, M. Goldman, and G. E. Grau. 1997. Interleukin-10 modulates susceptibility in experimental cerebral malaria. Immunology 91:536-540.
4. de Waal Malefijt, R., R. J. Haanen, H. Spits, M. G. Roncarolo, A. te Velde, C. Figdor, K. Johnson, R. Kastelein, H. Yssel, and J. E. de Vries. 1991. IL-10 and viral IL-10 strongly reduce antigen-specific human T cell proliferation by diminishing the antigen-presenting capacity of monocytes via down-regulation of class II major histocompatibility complex expression. J. Exp. Med. 174:915-924.
5. de Waal Malefijt, R., H. Yssel, and J. E. de Vries. 1993. Direct effects of IL-10 on subsets of human CD4 T cell clones and resting T cells. Specific inhibition of IL-2 production and proliferation. J. Immunol. 150:4754-4765.
6. Ding, L., P. S. Linsley, L. Y. Huang, R. N. Germain, and E. M. Shevach. 1993. IL-10 inhibits macrophage costimulatory activity by selectively inhibiting the up-regulation of B7 expression. J. Immunol. 151:1224-1234.
7. Elhassan, I. M., L. Hviid, G. Satti, B. Akerstrom, P. H. Jacobsen, J. B. Jensen and T. G. Theander. 1994. Evidence of endothehal inflammation, T cell activation, and T cell reallocation in uncomplicated Plasmodium falciparum malaria. Am. J. Trop. Med. Hyg. 51:372-379.
8. Finnemann, S., P. G. Kremsner, M. F. Chaves, C. Schumacher, S. Neifer, and U. Bienzle. 1992. Antibody response in Plasmodium vinckei malaria after treatment with chloroquine and adjuvant interferon-gamma. Parasitol. Res. 78:629-634.
9. Ho, M., H. K. Webster, B. Green, S. Looareesuwan, S. Kongchareon, and N. J. White. 1988. Defective production of and response to IL-2 in acute human falciparum malaria. J. Immunol. 141:2755-2759.
10. Hommel, M. 1997. Modulation of host cell receptors: a mechanism for the survival of malaria parasites. Parasitology 115:45-54.
11. Hviid, L., J. A. L. Kurtzhals, B. Q. Goka, J. O. Oliver-Commey, F. K. Nkrumah, and T. G. Theander. 1997. Rapid reemergence of T cells into peripheral circulation following treatment of severe and uncomplicated Plasmodium falciparum malaria. Infect. Immun. 65:4090-4093.
12. Hviid, L., T. G. Theander, N. H. Abdulhadi, A. Abu-Zeid, R. A. Bayoumi, and J. B. Jensen. 1991. Transient depletion of T cells with high LFA-1 expression from peripheral circulation during acute Plasmodium falciparum malaria. Eur. J. Immunol. 21:1249-1253.
13. Jacobs, P., D. Radzioch, and M. M. Stevenson. 1996. A Th1-associated increase in tumor necrosis factor alpha expression in the spleen correlates with resistance to blood-stage malaria in mice. Infect. Immun. 64:535-541.
14. Jacobs, P., D. Radzioch, and M. M. Stevenson. 1996. In vivo regulation of nitric oxide production by tumor necrosis factor alpha and gamma interferon, but not by interleukin-4, during blood stage malaria in mice. Infect. Immun. 64:44-49.
15. Jung, T., U. Schauer, C. Heusser, C. Neumann, and C. Rieger. 1993. Detection of intracellular cytokines by flow cytometry. J. Immunol. Methods 159: 197-207.
16. Kremsner, P. G., S. Neifer, S. Schermuck, M. Ferreira Chaves, K. Sliwa, and U. Bienzle. 1991. Interferon-γ enhances the effect of antimalarial chemotherapy in murine Plasmodium vinckei malaria. J. Infect. Dis. 163: 1161-1163.
17. Kremsner, P. G., G. M. Zotter, H. Feldmeier, W. Graninger, R. M. Rocha, R. Jansen-Rosseck, and U. Bienzle. 1990. Immune response during and after Plasmodium falciparum infection. J. Infect. Dis. 161:1025-1028.
18. Kumaratilake, L. M., and A. Ferrante. 1992. IL-4 inhibits macrophage-mediated killing of Plasmodium falciparum in vitro. A possible parasite-immune evasion mechanism. J. Immunol. 149:194-199.
19. Linke, A., R. Kühn, W. Müller, N. Honarvar, C. Li, and J. Langhorne. 1996. Plasmodium chabaudi chabaudi: differential susceptibility of gene-targeted mice deficient in IL-10 to an erythrocytic-stage infection. Exp. Parasitol. 84:253-263.
20. Mohan, K., P. Moulin, and M. M. Stevenson. 1997. Natural killer cell cytokine production, not cytotoxicity, contributes to resistance against blood-stage Plasmodium chabaudi AS infection. J. Immunol. 159:4990-4998.
21. Perlmann, H., S. Kumar, J. M. Vinetz, M. Kullberg, L. H. Miller, and P. Perlmann. 1995. Cellular mechanisms in the immune response to malaria in Plasmodium vinckei-infected mice. Infect. Immun. 63:3987-3993.
22. Schmidt-Ott, R., D. Luckner, L. G. Lehman, B. Lell, P. Matousek, B. Greve, and P. G. Kremsner. 1997. Sulfadoxine/pyrimethamine for treating uncomplicated Plasmodium falciparum malaria in young children in Gabon. Trans. R. Soc. Trop. Med. Hyg. 91:578-579.
23. Sedegah, M., F. Finkelman, and S. L. Hoffman. 1994. Interleukin 12 induction of interferon γ-dependent protection against malaria. Proc. Natl. Acad. Sci. USA 91:10700-10702.
24. Stevenson, M. M., and M. F. Tam. 1993. Differential induction of helper T cell subsets during blood-stage Plasmodium chabaudi AS infection in resistant and susceptible mice. Clin. Exp. Immunol. 92:77-83.
25. Stevenson, M. M., M. F. Tam, S. F. Wolf, and A. Sher. 1995. IL-12-induced protection against blood-stage Plasmodium chabaudi AS requires IFN-γ and TNF-α and occurs via a nitric oxide-dependent mechanism. J. Immunol. 155:2545-2556.
26. Taylor-Robinson, A. W. 1998. Immunoregulation of malarial infection: balancing the vices and virtues. Int. J. Parasitol. 28:135-148.
27. Taylor-Robinson, A. W., and M. Looker. 1998. Sensitivity of malaria parasites to nitric oxide at low oxygen tensions. Lancet 351:1630. (Letter.)
28. Taylor-Robinson, A. W., R. S. Phillips, A. Severn, S. Moncada, and F. Y. Liew. 1993. The role of Th1 and Th2 cells in a rodent malaria infection. Science 260:1931-1934.
29. Troye-Blomberg, M., K. Berzins, and P. Perlmann. 1994. T-cell control of immunity to the asexual blood stages of the malaria parasite. Crit. Rev. Immunol. 14:131-155.
30. Urban, J. F., N. Noben-Trauth, D. D. Donaldson, K. B. Madden, S. C. Morris, M. Collins, and F. D. Finkelman. 1998. IL-13, IL-4Rα, and Stat6 are required for the expulsion of the gastrointestinal nematode parasite Nippostrongylus brasiliensis. Immunity 8:255-264.
31. Von der Weid, T., M. Kopf, G. Köhler, and J. Langhorne. 1994. The immune response to Plasmodium chabaudi malaria in interleukin-4-deficient mice. Eur. J. Immunol. 24:2285-2293.
32. Wildling, E., S. Winkler, P. G. Kremsner, C. Brandts, L. Jenne, and W. H. Wernsdorfer. 1995. Malaria epidemiology in the province of Moyen Ogooué, Gabon. Trop. Med. Parasitol. 46:77-82.
33. Willheim, M., C. Ebner, K. Baier, W. Kern, K. Schrattbauer, R. Thien, D. Kraft, H. Breiteneder, W. Reinisch, and O. Scheiner. 1997. Cell surface characterization of T lymphocytes and allergen-specific T cell clones: correlation of CD26 expression with Th1 subsets. J. Allergy Clin. Immunol. 100: 348-355.
34. Windhagen, A., D. E. Anderson, A. Carrizosa, R. E. Williams, and D. A. Hafler. 1996. IL-12 induces human T cells secreting IL-10 with IFN-γ. J. Immunol. 157:1127-1131.