-
1
-
-
80051553765
-
The dynamics of cortical and hippocampal atrophy in alzheimer disease
-
Sabuncu, M.R.; Desikan, R.S.; Sepulcre, J.; Yeo, B.T.T.; Liu, H.; Schhmansky, N.J.; Buckner, R.L.; Sperling, R.A.; Fischl, B. The Dynamics of Cortical and Hippocampal Atrophy in Alzheimer Disease. Arch. Neurol., 2011, 68, 1040-1048.
-
(2011)
Arch. Neurol.
, vol.68
, pp. 1040-1048
-
-
Sabuncu, M.R.1
Desikan, R.S.2
Sepulcre, J.3
Yeo, B.T.T.4
Liu, H.5
Schhmansky, N.J.6
Buckner, R.L.7
Sperling, R.A.8
Fischl, B.9
-
2
-
-
84855762409
-
DNA methylation of the 50-untranslated region at +298 and +351 represses BACE1 expression in mouse BV-2 microglial cells
-
Byun, C.J.; Seo, J.; Jo, S.A.; Park, Y.J.; Klug, M.; Rehli, M.; Park, M-H.; Jo, I. DNA methylation of the 50-untranslated region at +298 and +351 represses BACE1 expression in mouse BV-2 microglial cells. Biochem. Bioph. Res. Co., 2012, 417, 387-392.
-
(2012)
Biochem. Bioph. Res. Co.
, vol.417
, pp. 387-392
-
-
Byun, C.J.1
Seo, J.2
Jo, S.A.3
Park, Y.J.4
Klug, M.5
Rehli, M.6
Park, M.-H.7
Jo, I.8
-
3
-
-
84882779807
-
Avaliação neuropsicológica na doença de Alzheimer e no comprometimento cognitivo leve
-
Hamdan, A.C. Avaliação neuropsicológica na doença de Alzheimer e no comprometimento cognitivo leve. Psicol. Argum., 2008, 26, 183-192.
-
(2008)
Psicol. Argum.
, vol.26
, pp. 183-192
-
-
Hamdan, A.C.1
-
4
-
-
78650673350
-
Potential predictors of hippocampal atrophy in alzheimer's disease
-
Dhikav, V.; Anand, K. Potential Predictors of Hippocampal Atrophy in Alzheimer's Disease. Drug. Aging, 2011, 28, 1-11.
-
(2011)
Drug. Aging
, vol.28
, pp. 1-11
-
-
Dhikav, V.1
Anand, K.2
-
5
-
-
84859325175
-
Defining Alzheimer as a common age-related neurodegenerative process not inevitably leading to dementia
-
Ferrer, I. Defining Alzheimer as a common age-related neurodegenerative process not inevitably leading to dementia. Prog. Neurobiol., 2012, 97, 38-51.
-
(2012)
Prog. Neurobiol.
, vol.97
, pp. 38-51
-
-
Ferrer, I.1
-
6
-
-
84858148877
-
Antioxidant clinical trials in mild cognitive impairment and Alzheimer's disease
-
Mecocci, P.; Polidori, M.C.; Antioxidant clinical trials in mild cognitive impairment and Alzheimer's disease. Biochim.. Bioph.. Acta., 2012, 1822, 631-638.
-
(2012)
Biochim. Bioph. Acta.
, vol.1822
, pp. 631-638
-
-
Mecocci, P.1
Polidori, M.C.2
-
7
-
-
79952574501
-
Epidemiology of Alzheimer disease
-
Reitz, C.; Brayne, C.; Mayeux, R. Epidemiology of Alzheimer disease. Nat. Rev. Neurol., 2011, 7, 137-152.
-
(2011)
Nat. Rev. Neurol.
, vol.7
, pp. 137-152
-
-
Reitz, C.1
Brayne, C.2
Mayeux, R.3
-
8
-
-
0038240721
-
Causative and susceptibility genes for Alzheimer's disease: A review
-
Rocchi, A.; Pellegrini, S.; Siciliano, G.; Murri, L. Causative and susceptibility genes for Alzheimer's disease: a review. Brain Res. Bull., 2003, 61, 1-24.
-
(2003)
Brain Res. Bull.
, vol.61
, pp. 1-24
-
-
Rocchi, A.1
Pellegrini, S.2
Siciliano, G.3
Murri, L.4
-
9
-
-
84857788978
-
Insulin signaling, glucose metabolism and mitochondria: Major players in Alzheimer's disease and diabetes interrelation
-
Correia, S.C.; Santos, R.X.; Carvalho, C.; Cardoso, S.; Candeias, E.; Santos, M.S.; Oliveira, C.R.; Moreira, P.I. Insulin signaling, glucose metabolism and mitochondria: Major players in Alzheimer's disease and diabetes interrelation. Brain Res., 2012, 1441, 64 - 78
-
(2012)
Brain Res.
, vol.1441
, pp. 64-78
-
-
Correia, S.C.1
Santos, R.X.2
Carvalho, C.3
Cardoso, S.4
Candeias, E.5
Santos, M.S.6
Oliveira, C.R.7
Moreira, P.I.8
-
10
-
-
84859135159
-
Statistical analysis, trial design and duration in Alzheimer's disease clinical trials: A review
-
Thompson, P.A.; Wright, D.E.; Counsell, C.E.; Zajicek, J. Statistical analysis, trial design and duration in Alzheimer's disease clinical trials: a review. Int. Psychogeriatr., 2012, 24, 689-697.
-
(2012)
Int. Psychogeriatr.
, vol.24
, pp. 689-697
-
-
Thompson, P.A.1
Wright, D.E.2
Counsell, C.E.3
Zajicek, J.4
-
11
-
-
84876107554
-
A comprehensive review on synthesis and designing aspects of coumarin derivatives as monoamine oxidase inhibitors for depression and Alzheimer's disease
-
Patil, P.O.; Bari, S.B.; Firke, S.D.; Deshmukh, P.K.; Donda, S.T.; Patil, D.A. A comprehensive review on synthesis and designing aspects of coumarin derivatives as monoamine oxidase inhibitors for depression and Alzheimer's disease. Bioorg. Med. Chem., 2013, 21, 2434-2450.
-
(2013)
Bioorg. Med. Chem.
, vol.21
, pp. 2434-2450
-
-
Patil, P.O.1
Bari, S.B.2
Firke, S.D.3
Deshmukh, P.K.4
Donda, S.T.5
Patil, D.A.6
-
12
-
-
84874680950
-
The development of effective biomarkers for Alzheimer's disease: A review
-
Henry, M.S.; Passmore, A.P.; Todd, S.; McGuinness, B.; Craig, D.; Johnston, J.A. The development of effective biomarkers for Alzheimer's disease: a review. Int. J. Geriatr. Psych., 2013, 28, 331- 340.
-
(2013)
Int. J. Geriatr. Psych.
, vol.28
, pp. 331-340
-
-
Henry, M.S.1
Passmore, A.P.2
Todd, S.3
McGuinness, B.4
Craig, D.5
Johnston, J.A.6
-
13
-
-
84872699164
-
Review: Systemic inflammation and alzheimer's disease
-
Holmes, C. Review: Systemic inflammation and Alzheimer's disease. Neuropath. Appl. Neuro., 2013, 39, 51-68.
-
(2013)
Neuropath. Appl. Neuro.
, vol.39
, pp. 51-68
-
-
Holmes, C.1
-
14
-
-
84871341948
-
Evolution of the evidence on the effectiveness and cost-effectiveness of acetylcholinesterase inhibitors and memantine for Alzheimer's disease: Systematic review and economic model
-
Hyde,C.; Peters,J.; Bond.M.; Rogers,G.; Hoyle,M.; Anderson, R.; Jeffreys, M.; Davis, S.; Thokala, P.; Moxham, T. Evolution of the evidence on the effectiveness and cost-effectiveness of acetylcholinesterase inhibitors and memantine for Alzheimer's disease: systematic review and economic model. Age Ageing., 2013, 42, 14- 20.
-
(2013)
Age Ageing.
, vol.42
, pp. 14-20
-
-
Hyde, C.1
Peters, J.2
Bond, M.3
Rogers, G.4
Hoyle, M.5
Anderson, R.6
Jeffreys, M.7
Davis, S.8
Thokala, P.9
Moxham, T.10
-
15
-
-
84877873373
-
A review on cholinesterase inhibitors for Alzheimer's disease
-
Anand, P.; Singh, B. A review on cholinesterase inhibitors for Alzheimer's disease. Arch. Pharm. Res., 2013, 36, 375-399.
-
(2013)
Arch. Pharm. Res.
, vol.36
, pp. 375-399
-
-
Anand, P.1
Singh, B.2
-
16
-
-
81055156769
-
Effect of cholineacetyltransferase activity and choline recycle ratio on diffusion-reaction modeling, bifurcation and chaotic behavior of acetylcholine neurocycle and their relation to Alzheimer's and Parkinson's diseases
-
Mustafa, I.H.; Elkamel, A.; Chen, P.; Ibrahim, G.; Elnashaie, S.S. E. H. Effect of cholineacetyltransferase activity and choline recycle ratio on diffusion-reaction modeling, bifurcation and chaotic behavior of acetylcholine neurocycle and their relation to Alzheimer's and Parkinson's diseases. Chem. Eng. Sci., 2012, 68, 19-35.
-
(2012)
Chem. Eng. Sci.
, vol.68
, pp. 19-35
-
-
Mustafa, I.H.1
Elkamel, A.2
Chen, P.3
Ibrahim, G.4
Elnashaie, S.S.E.H.5
-
17
-
-
0020545051
-
Alzheimer's disease: Choline acetyltransferase activity in brain tissue from clinical and pathological subgroups
-
Bird, T.D.; Stranahan, S.; Sumi, S.M.; Raskind, M. Alzheimer's disease: choline acetyltransferase activity in brain tissue from clinical and pathological subgroups. Ann. Neurol., 1983, 14, 284-293.
-
(1983)
Ann. Neurol.
, vol.14
, pp. 284-293
-
-
Bird, T.D.1
Stranahan, S.2
Sumi, S.M.3
Raskind, M.4
-
18
-
-
76849095847
-
The clinical use of structural MRI in Alzheimer disease
-
Frisoni, G.B. The clinical use of structural MRI in Alzheimer disease. Nat. Rev. Neurol., 2010, 6, 67-77.
-
(2010)
Nat. Rev. Neurol.
, vol.6
, pp. 67-77
-
-
Frisoni, G.B.1
-
19
-
-
0029968507
-
Acetylcholine muscarinic m2 receptor stimulated [35s]gtpgs binding shows regional selective changes in alzheimer's disease postmortem brain
-
Cowburn, R.F.; Wiehager, B.; Ravid, R.; Winblad, B. Acetylcholine Muscarinic M2 Receptor Stimulated [35S]GTPgS Binding Shows Regional Selective Changes in Alzheimer's Disease Postmortem Brain. Neurodegeneration., 1996, 5, 19-26.
-
(1996)
Neurodegeneration.
, vol.5
, pp. 19-26
-
-
Cowburn, R.F.1
Wiehager, B.2
Ravid, R.3
Winblad, B.4
-
20
-
-
0034732104
-
Allosteric modulation of nicotinic acetylcholine receptors as a treatment strategy for alzheimer's disease
-
Maelicke, A.; Albuquerque, E.X. Allosteric modulation of nicotinic acetylcholine receptors as a treatment strategy for Alzheimer's disease. Eur. J. Pharmacol., 2000, 393, 165-170.
-
(2000)
Eur. J. Pharmacol.
, vol.393
, pp. 165-170
-
-
Maelicke, A.1
Albuquerque, E.X.2
-
21
-
-
0242352648
-
Unique mechanism of action of alzheimer's drugs on brain nicotinic acetylcholine receptors and nmda receptors
-
Narahashi, T.; Marszalec, W.; Moriguchi, S.; Yeh, J. Z.; Zhao, X. Unique mechanism of action of Alzheimer's drugs on brain nicotinic acetylcholine receptors and NMDA receptors. Life Sci., 2003, 74, 281-291.
-
(2003)
Life Sci.
, vol.74
, pp. 281-291
-
-
Narahashi, T.1
Marszalec, W.2
Moriguchi, S.3
Yeh, J.Z.4
Zhao, X.5
-
22
-
-
0033841591
-
Expression of nicotinic acetylcholine receptors in Alzheimer's disease: Postmortem investigations and experimental approaches
-
Wevers, A.; Burghaus, L.; Moser, N.; Witter, B.; Steinlein, O.K.; Schütz, U.; Achnitz, B.; Krempel, U.; Nowacki, S.; Pilz, K.; Stoodt, J.; Lindstrom, J.; Vos, R.A.I.D.; Steur, J.; Schröder, H. Expression of nicotinic acetylcholine receptors in Alzheimer's disease: postmortem investigations and experimental approaches. Behavioural Brain Res., 2000, 113, 207-215.
-
(2000)
Behavioural Brain Res.
, vol.113
, pp. 207-215
-
-
Wevers, A.1
Burghaus, L.2
Moser, N.3
Witter, B.4
Steinlein, O.K.5
Schütz, U.6
Achnitz, B.7
Krempel, U.8
Nowacki, S.9
Pilz, K.10
Stoodt, J.11
Lindstrom, J.12
Vos, R.A.I.D.13
Steur, J.14
Schröder, H.15
-
23
-
-
84866419359
-
An in silico approach for the identification of inhibitors against Acetylcholinesterase
-
Remya, C.; Dileep, K.V.; Tintu, I.; Variyar, E.J.; Sadasivan, C. An in silico approach for the identification of inhibitors against Acetylcholinesterase. Med. Chem. Res., 2012, 21, 2779-2787.
-
(2012)
Med. Chem. Res.
, vol.21
, pp. 2779-2787
-
-
Remya, C.1
Dileep, K.V.2
Tintu, I.3
Variyar, E.J.4
Sadasivan, C.5
-
24
-
-
84856218975
-
Anticholinesterase potential of flavonols from paper mulberry (Broussonetia papyrifera) and their kinetic studies
-
Ryu, H.W.; Curtis-Long, M.J.; Jung, I.Y.; Kim, D.S.; Kang, K.Y.; Park, K.H. Anticholinesterase potential of flavonols from paper mulberry (Broussonetia papyrifera) and their kinetic studies. Food Chem., 2012, 132, 1244-1250.
-
(2012)
Food Chem.
, vol.132
, pp. 1244-1250
-
-
Ryu, H.W.1
Curtis-Long, M.J.2
Jung, I.Y.3
Kim, D.S.4
Kang, K.Y.5
Park, K.H.6
-
25
-
-
84862875257
-
Zinc and human health: An update
-
Chasapis, C.T.; Loutsidou, A.C.; Spiliopoulou, C.A.; Stefanidou, M.E. Zinc and human health: an update. Arch. Toxicol., 2012, 86, 521-534.
-
(2012)
Arch. Toxicol.
, vol.86
, pp. 521-534
-
-
Chasapis, C.T.1
Loutsidou, A.C.2
Spiliopoulou, C.A.3
Stefanidou, M.E.4
-
26
-
-
0034914927
-
Antioxidant defences and oxidative stress markers in erythrocytes and plasma from normally nourished elderly Alzheimer patients
-
Bourdel-Marchasson, I.; Delmas-Beauvieux, M.-C.;Peuchant, E.; Richard-Harston, S.; Decamps, A.; Reignier, B.; Emeriau, J.P.; Rainfray, M. Antioxidant defences and oxidative stress markers in erythrocytes and plasma from normally nourished elderly Alzheimer patients. Age. Ageing, 2000, 30, 235-241.
-
(2000)
Age. Ageing
, vol.30
, pp. 235-241
-
-
Bourdel-Marchasson, I.1
Delmas-Beauvieux, M.-C.2
Peuchant, E.3
Richard-Harston, S.4
Decamps, A.5
Reignier, B.6
Emeriau, J.P.7
Rainfray, M.8
-
27
-
-
84858161403
-
Elevation of glutathione as a therapeutic strategy in Alzheimer disease
-
Pocernich, C. B; Butterfield, D. A. Elevation of glutathione as a therapeutic strategy in Alzheimer disease. Bioch. Bioph. Acta., 2012, 625-630.
-
(2012)
Bioch. Bioph. Acta.
, pp. 625-630
-
-
Pocernich, C.B.1
Butterfield, D.A.2
-
28
-
-
0042591280
-
Plasma antioxidants are similarly depleted in mild cognitive impairment and in Alzheimer's disease
-
Rinaldi, P.; Polidori, M.C.; Metastasio, A.; Mariani, E.; Mattiolo, P.; Cherubini, A.; Catani, M.; Cecchetti, R.; Senin, U.; Mecocci, P. Plasma antioxidants are similarly depleted in mild cognitive impairment and in Alzheimer's disease. Neurobiol. Aging., 2003, 24, 915-919.
-
(2003)
Neurobiol. Aging.
, vol.24
, pp. 915-919
-
-
Rinaldi, P.1
Polidori, M.C.2
Metastasio, A.3
Mariani, E.4
Mattiolo, P.5
Cherubini, A.6
Catani, M.7
Cecchetti, R.8
Senin, U.9
Mecocci, P.10
-
29
-
-
84655176377
-
Reactive oxygen species target specific tryptophan site in the mitochondrial ATP synthase
-
Rexroth, S.; Poetsch, A.; Rogner, M.; Hamann, A.; Werner, A.; Osiewacz, H.D.; Schafer, E.R.; Dencher, N.A. Reactive oxygen species target specific tryptophan site in the mitochondrial ATP synthase. Bioch. Bioph. Acta., 2012, 1817, 381-387.
-
(2012)
Bioch. Bioph. Acta.
, vol.1817
, pp. 381-387
-
-
Rexroth, S.1
Poetsch, A.2
Rogner, M.3
Hamann, A.4
Werner, A.5
Osiewacz, H.D.6
Schafer, E.R.7
Dencher, N.A.8
-
30
-
-
79952517451
-
Ibuprofen and Glutathione Conjugate as a Potential Therapeutic Agent for Treating Alzheimer's Disease
-
Pinnen, F.; Sozio, P.; Cornacchia, C.; Mollica, A.; Iannitelli, A.; D'Aurizio, E.; Cataldi, A.; Zara, S.; Nasuti, C.; Di Stefano, A. Ibuprofen and Glutathione Conjugate as a Potential Therapeutic Agent for Treating Alzheimer's Disease. Arch. Pharm. Chem. Life Sci., 2011, 11, 139-148.
-
(2011)
Arch. Pharm. Chem. Life Sci.
, vol.11
, pp. 139-148
-
-
Pinnen, F.1
Sozio, P.2
Cornacchia, C.3
Mollica, A.4
Iannitelli, A.5
D'Aurizio, E.6
Cataldi, A.7
Zara, S.8
Nasuti, C.9
Di Stefano, A.10
-
31
-
-
79961033321
-
The link between iron, metabolic syndrome, and Alzheimer's disease
-
Grünblatt, E.; Bartl, J.; Riederer, P. The link between iron, metabolic syndrome, and Alzheimer's disease. J. Neural. Transm., 2011, 118, 371-379.
-
(2011)
J. Neural. Transm.
, vol.118
, pp. 371-379
-
-
Grünblatt, E.1
Bartl, J.2
Riederer, P.3
-
32
-
-
84866112645
-
Review: Quantifying mitochondrial dysfunction in complex diseases of aging
-
Horan, M. P.; Pichaud, N.; Ballard, J. W. O. Review: Quantifying Mitochondrial Dysfunction in Complex Diseases of Aging. J. Gerontol. A-Biol., 2012, 67, 1022-1035.
-
(2012)
J. Gerontol. A-Biol.
, vol.67
, pp. 1022-1035
-
-
Horan, M.P.1
Pichaud, N.2
Ballard, J.W.O.3
-
33
-
-
84870570226
-
Insulin: An emerging treatment for alzheimer's disease dementia?
-
Morris, J. K.; Burns, J. M. Insulin: An Emerging Treatment for Alzheimer's Disease Dementia?, Curr. Neurol. Neurosci., 2012, 12, 520-527.
-
(2012)
Curr. Neurol. Neurosci.
, vol.12
, pp. 520-527
-
-
Morris, J.K.1
Burns, J.M.2
-
34
-
-
67349085203
-
Uncontrolled diabetes increases the risk of Alzheimer's disease: A population-based cohort study
-
Xu, W. L.; Von Strauss, E.; Qiu, C. X.; Winblad, B.; Fratiglioni, L. Uncontrolled diabetes increases the risk of Alzheimer's disease: a population-based cohort study. Diabetologia, 2009, 52, 1031-1039.
-
(2009)
Diabetologia
, vol.52
, pp. 1031-1039
-
-
Xu, W.L.1
Von Strauss, E.2
Qiu, C.X.3
Winblad, B.4
Fratiglioni, L.5
-
35
-
-
84863084862
-
Plasma oxidative stress parameters in men and women with early stage Alzheimer type dementia
-
Puertas, M. C.; Martínez-Martos, J. M.; Carrera, M. P.; Mayas, M. D. Plasma oxidative stress parameters in men and women with early stage Alzheimer type dementia. Exp. Gerontol., 2012, 47, 625-630.
-
(2012)
Exp. Gerontol.
, vol.47
, pp. 625-630
-
-
Puertas, M.C.1
Martínez-Martos, J.M.2
Carrera, M.P.3
Mayas, M.D.4
-
36
-
-
84863230675
-
Age- Dependent and Tissue-Related Glutathione Redox Status in a Mouse Model of Alzheimer's Disease
-
Zhang, C.; Rodriguez, C.; Spaulding, J.; Aw, T. Y.; Feng, J. Age- Dependent and Tissue-Related Glutathione Redox Status in a Mouse Model of Alzheimer's Disease. J. Alzheimers Dis., 2012, 28, 655-666.
-
(2012)
J. Alzheimers Dis.
, vol.28
, pp. 655-666
-
-
Zhang, C.1
Rodriguez, C.2
Spaulding, J.3
Aw, T.Y.4
Feng, J.5
-
37
-
-
0032853190
-
Normal cerebrospinal fluid glutathione concentrations in parkinson's disease, alzheimer's disease and multiple system atrophy
-
Konings, C. H.; Kuiper, M. A.; Mulder, C.; Scheltens, Ph.; Wolters, E. Ch. Normal cerebrospinal fluid glutathione concentrations in Parkinson's disease, Alzheimer's disease and multiple system atrophy. J. Neurol. Sci., 1999, 168, 112-115.
-
(1999)
J. Neurol. Sci.
, vol.168
, pp. 112-115
-
-
Konings, C.H.1
Kuiper, M.A.2
Mulder, C.3
Scheltens, P.H.4
Wolters, E.C.H.5
-
38
-
-
72449133293
-
Basal cerebral metabolism may modulate the cognitive effects of Aβ in mild cognitive impairment: An example of brain reserve
-
Cohen, A. D.; Price, J. C.; Weissfeld, L. A.; James, J.; Rosario, B. L.; Bi, W.; Nebes, R. D.; Saxton, J. A.; Snitz, B. E.; Aizestein, H. A.; Wolk, D. A.; Dekosky, S. T.; Mathis, C. A.; Klunk, W. Basal Cerebral Metabolism May Modulate the Cognitive Effects of Aβ in Mild Cognitive Impairment: An Example of Brain Reserve. J. Neurosci., 2009, 25, 14770-1478.
-
(2009)
J. Neurosci.
, vol.25
, pp. 14770-11488
-
-
Cohen, A.D.1
Price, J.C.2
Weissfeld, L.A.3
James, J.4
Rosario, B.L.5
Bi, W.6
Nebes, R.D.7
Saxton, J.A.8
Snitz, B.E.9
Aizestein, H.A.10
Wolk, D.A.11
Dekosky, S.T.12
Mathis, C.A.13
Klunk, W.14
-
39
-
-
0031724265
-
Enhanced oxidative stress and altered antioxidants in brains of Bcl-2-Deficient mice
-
Hochman, A.; Gorodin, S.; Korsmeyer, S.; Ziv, I.; Melamed, E.; Offen, D. Enhanced Oxidative Stress and Altered Antioxidants in Brains of Bcl-2-Deficient Mice. J. Neurochem., 1998, 71, 741 -748.
-
(1998)
J. Neurochem.
, vol.71
, pp. 741-748
-
-
Hochman, A.1
Gorodin, S.2
Korsmeyer, S.3
Ziv, I.4
Melamed, E.5
Offen, D.6
-
40
-
-
33749506795
-
Two-year follow-up of amyloid deposition in patients with Alzheimer's disease
-
Engler, H.; Forsberg, A.; Almkvist, O.; Blomquist, G.; Larsson, E.; Savitcheva, I.; Wall, A.; Ringheim, A.; Langstrom, B.; Nordberg, A. Two-year follow-up of amyloid deposition in patients with Alzheimer's disease. Brain, 2006, 129, 2856-2866.
-
(2006)
Brain
, vol.129
, pp. 2856-2866
-
-
Engler, H.1
Forsberg, A.2
Almkvist, O.3
Blomquist, G.4
Larsson, E.5
Savitcheva, I.6
Wall, A.7
Ringheim, A.8
Langstrom, B.9
Nordberg, A.10
-
41
-
-
80053336026
-
A randomized, double-blind, placebocontrolled trial of simvastatin to treat Alzheimer disease
-
Sano, M.; Bell, K. L.; Galasko, D.; Galvin, J. E.; Thomas, R. G.; Dyck, C. H.; Aisen, P. S. A randomized, double-blind, placebocontrolled trial of simvastatin to treat Alzheimer disease. Neurol., 2011, 77, 556-563.
-
(2011)
Neurol.
, vol.77
, pp. 556-563
-
-
Sano, M.1
Bell, K.L.2
Galasko, D.3
Galvin, J.E.4
Thomas, R.G.5
Dyck, C.H.6
Aisen, P.S.7
-
42
-
-
84865617768
-
Attenuation of Aβ-induced neurotoxicity by thymoquinone via inhibition of mitochondrial dysfunction and oxidative stress
-
Khan, A.; Vaibhav, K.; Javed, H.; Khan, M.M.; Tabassum, R.; Ahmed, M.E.; Sristava, P.; Khuwaja, G.; Islam, F.; Siddiqui, S.; Shafi, M.M.; Islam, F. Attenuation of Aβ-induced neurotoxicity by thymoquinone via inhibition of mitochondrial dysfunction and oxidative stress. Mol. Cell. Biochem., 2012, 369, 55-65.
-
(2012)
Mol. Cell. Biochem.
, vol.369
, pp. 55-65
-
-
Khan, A.1
Vaibhav, K.2
Javed, H.3
Khan, M.M.4
Tabassum, R.5
Ahmed, M.E.6
Sristava, P.7
Khuwaja, G.8
Islam, F.9
Siddiqui, S.10
Shafi, M.M.11
Islam, F.12
-
43
-
-
84858046578
-
Neuropathological alterations in alzheimer disease. Cold spring harb
-
Serrano-Pozo, A.; Frosch, M. P.; Masliah, E.; Hyman, B. T. Neuropathological Alterations in Alzheimer Disease. Cold Spring Harb. Perspect. Med., 2011, 1, a006189.
-
(2011)
Perspect. Med.
, vol.1
-
-
Serrano-Pozo, A.1
Frosch, M.P.2
Masliah, E.3
Hyman, B.T.4
-
44
-
-
78650850292
-
Is brain amyloid production a cause or a result of dementia of the Alzheimer type?
-
Stuble, R.G.; Ala, T.; Patrylo, P.R.; Brewer, G.J.; Yan, X-X. Is brain amyloid production a cause or a result of dementia of the Alzheimer type? J. Alzheimers Dis., 2010, 22, 393-399.
-
(2010)
J. Alzheimers Dis.
, vol.22
, pp. 393-399
-
-
Stuble, R.G.1
Ala, T.2
Patrylo, P.R.3
Brewer, G.J.4
Yan, X.-X.5
-
45
-
-
84862897184
-
The role of APP proteolytic processing in lipid metabolism
-
Grimm, M.O.W.; Rothhaar, T.L.; Hartmann, T. The role of APP proteolytic processing in lipid metabolism, Exp. Brain Res., 2012, 217, 365-375.
-
(2012)
Exp. Brain Res.
, vol.217
, pp. 365-375
-
-
Grimm, M.O.W.1
Rothhaar, T.L.2
Hartmann, T.3
-
46
-
-
84861235844
-
Axonal transport of APP and the spatial regulation of APP cleavage and function in neuronal cells
-
Brunholz, S.; Sisodia, S.; Lorenzo, A.; Deyts, C.; Kins, S.; Morfini, G. Axonal transport of APP and the spatial regulation of APP cleavage and function in neuronal cells. Exp. Brain Res., 2012, 217, 353-364.
-
(2012)
Exp. Brain Res.
, vol.217
, pp. 353-364
-
-
Brunholz, S.1
Sisodia, S.2
Lorenzo, A.3
Deyts, C.4
Kins, S.5
Morfini, G.6
-
47
-
-
16444379174
-
Delta;- Glutamylcysteine ethyl ester-Induced up-Regulation of glutathione protects neurons against Aβ (1-42)-Mediated oxidative stress and neurotoxicity: Implications for alzheimer's disease
-
Boyd-Kimball, D.; Sultana, R.; Abdul, H.M.; Butterfield, D.A. Delta;- Glutamylcysteine Ethyl Ester-Induced Up-Regulation of Glutathione Protects Neurons Against Aβ (1-42)-Mediated Oxidative Stress and Neurotoxicity:Implications for Alzheimer's Disease. J. Neurosci. Res., 2005, 79, 700-706.
-
(2005)
J. Neurosci. Res.
, vol.79
, pp. 700-706
-
-
Boyd-Kimball, D.1
Sultana, R.2
Abdul, H.M.3
Butterfield, D.A.4
-
48
-
-
33750589818
-
CSF phosphorylated tau protein correlates with neocortical neurofibrillary pathology in Alzheimer's disease
-
Buerger, K.; Ewers, M.; Pirttila, T.; Zinkowski, R.; Alafuzoff, I.; Teipel, S.J.; DeBernardis, J.; Kerkman, D.; McCulloch, C.; Soininen, H.; Hampel, H. CSF phosphorylated tau protein correlates with neocortical neurofibrillary pathology in Alzheimer's disease. Brain, 2006, 129, 3035-3041.
-
(2006)
Brain
, vol.129
, pp. 3035-3041
-
-
Buerger, K.1
Ewers, M.2
Pirttila, T.3
Zinkowski, R.4
Alafuzoff, I.5
Teipel, S.J.6
Debernardis, J.7
Kerkman, D.8
McCulloch, C.9
Soininen, H.10
Hampel, H.11
-
49
-
-
0031947586
-
Cerebrospinal fluid tau protein as a biochemical marker for Alzheimer's disease: A community based follow up study
-
Andreasen, N.; Vanmechelen, E.; Van de Voorde, A.; Davidsson, P.; Tarvonen, S.; Raiha, I.; Sourander, L.; Winblad, B.; Blennow, K. Cerebrospinal fluid tau protein as a biochemical marker for Alzheimer's disease: a community based follow up study. J. Neurol. Neurosurg. Psych., 1998, 64, 298-305.
-
(1998)
J. Neurol. Neurosurg. Psych.
, vol.64
, pp. 298-305
-
-
Andreasen, N.1
Vanmechelen, E.2
Van De Voorde, A.3
Davidsson, P.4
Tarvonen, S.5
Raiha, I.6
Sourander, L.7
Winblad, B.8
Blennow, K.9
-
50
-
-
84893776217
-
Amyloid-β and tau in Alzheimer's disease
-
poster
-
LaFerla, F.M. Amyloid-β and tau in Alzheimer's disease. Nat. Rev. Neurosci., 2008, 9(5), poster.
-
(2008)
Nat. Rev. Neurosci.
, vol.9
, pp. 5
-
-
Laferla, F.M.1
-
51
-
-
84857620173
-
Acetylated tau, a novel pathological signature in Alzheimer's disease and other tauopathies
-
Irwin, D.J.; Cohen, T.J.; Grossman, M.; Arnold, S.E.; Xie, S.X.; Lee, M-Y.; Trojanowski, J.Q.; Acetylated tau, a novel pathological signature in Alzheimer's disease and other tauopathies. Brain, 2012, 135, 807-818.
-
(2012)
Brain
, vol.135
, pp. 807-818
-
-
Irwin, D.J.1
Cohen, T.J.2
Grossman, M.3
Arnold, S.E.4
Xie, S.X.5
Lee, M.-Y.6
Trojanowski, J.Q.7
-
52
-
-
0032196604
-
Modification of tau to an Alzheimer's type protein interferes with its interaction with microtubules
-
Gonzalez, C.; Farias, G.; Maccioni.; R.B. Modification of tau to an Alzheimer's type protein interferes with its interaction with microtubules. Cell. Mol. Biol., 1998, 44, 1117-1127.
-
(1998)
Cell. Mol. Biol.
, vol.44
, pp. 1117-1127
-
-
Gonzalez, C.1
Farias, G.2
Maccioni, R.B.3
-
53
-
-
0031054759
-
Immunological characterization of epitopes on tau of Alzheimer's type and chemically modified tau
-
Farias, G.; Gonzalez, C.; Maccioni, R. B. Immunological characterization of epitopes on tau of Alzheimer's type and chemically modified tau. Mol. Cell. Biochem., 1997, 168, 59-66.
-
(1997)
Mol. Cell. Biochem.
, vol.168
, pp. 59-66
-
-
Farias, G.1
Gonzalez, C.2
Maccioni, R.B.3
-
54
-
-
77249098331
-
Increased metabolic vulnerability in early-onset Alzheimer's disease is not related to amyloid burden
-
Rabinovici, G.D.; Furst, A.J.; Alkalay, A.; Racine, C.A.; O'Neil, J.; Janabi, M.; Baker, S.L.; Agarwal, N.; Bonasera, S.J.; Mormino, E.C.; Weiner, M.W.; Gorno-Tempini, M.L.; Rosen, H.J.; Miller, B.L.; Jagust, W.J. Increased metabolic vulnerability in early-onset Alzheimer's disease is not related to amyloid burden, Brain, 2010, 133, 512-528.
-
(2010)
Brain
, vol.133
, pp. 512-528
-
-
Rabinovici, G.D.1
Furst, A.J.2
Alkalay, A.3
Racine, C.A.4
O'Neil, J.5
Janabi, M.6
Baker, S.L.7
Agarwal, N.8
Bonasera, S.J.9
Mormino, E.C.10
Weiner, M.W.11
Gorno-Tempini, M.L.12
Rosen, H.J.13
Miller, B.L.14
Jagust, W.J.15
-
55
-
-
0029671451
-
Water-soluble Aβ (N-40, N-42) Oligomers in Normal and Alzheimer Disease Brains
-
Kuo, Y-M.; Emmerling, M.R.; Kasunic, T.C.; Kirkpatrick, J.B., Murdoch, G.H.; Ball, M.J.; Roher, A.E. Water-soluble Aβ (N-40, N-42) Oligomers in Normal and Alzheimer Disease Brains. J. Biol. Chem., 1996, 271, 4077-4081.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 4077-4081
-
-
Kuo, Y.-M.1
Emmerling, M.R.2
Kasunic, T.C.3
Kirkpatrick, J.B.4
Murdoch, G.H.5
Ball, M.J.6
Roher, A.E.7
-
56
-
-
84856950778
-
Detrimental effects of arachidonic acid and its metabolites in cellular and mouse models of Alzheimer's disease: Structural insight
-
Amtul, Z.; Uhrig, M.; Wang, L.; Rozmahel, R.F.; Beyreuther, K. Detrimental effects of arachidonic acid and its metabolites in cellular and mouse models of Alzheimer's disease: structural insight. Neurobiol. Aging, 2012, 33, 831.e21-e31.
-
(2012)
Neurobiol. Aging
, vol.33
, Issue.831
-
-
Amtul, Z.1
Uhrig, M.2
Wang, L.3
Rozmahel, R.F.4
Beyreuther, K.5
-
57
-
-
77956313661
-
ABCG2 reduces ROS-mediated toxicity and inflammation: A potential role in Alzheimer's disease
-
Shen, S.; Callaghan, D.; Juzwik, C.; Xiong, H.; Huang, P.; Zhang, W. ABCG2 reduces ROS-mediated toxicity and inflammation: a potential role in Alzheimer's disease. J. Neurochem., 2010, 114, 1590-1604.
-
(2010)
J. Neurochem.
, vol.114
, pp. 1590-1604
-
-
Shen, S.1
Callaghan, D.2
Juzwik, C.3
Xiong, H.4
Huang, P.5
Zhang, W.6
-
58
-
-
84855798260
-
Enzymatic synthesis of substituted epicathechins for bioactivity studies in neurological disorders
-
Blount, J.W.; Ferruzzi, M.; Raftery, D.; Pasiinetti, G. M.; Dixon, R. A. Enzymatic synthesis of substituted epicathechins for bioactivity studies in neurological disorders. Biochem. Bioph. Res. Co., 2012, 417, 457-461.
-
(2012)
Biochem. Bioph. Res. Co.
, vol.417
, pp. 457-461
-
-
Blount, J.W.1
Ferruzzi, M.2
Raftery, D.3
Pasiinetti, G.M.4
Dixon, R.A.5
-
59
-
-
84878912705
-
IDE (rs6583817) polymorphism and type 2 diabetes differentially modify executive function in older adults
-
McFall, G. P.; Wiebe, S.A.; Westaway, D.; Jhamandas, J.; Dixon, R. A. IDE (rs6583817) polymorphism and type 2 diabetes differentially modify executive function in older adults. Neurobiol. Aging, 2013, 34, 2208-2216.
-
(2013)
Neurobiol. Aging
, vol.34
, pp. 2208-2216
-
-
McFall, G.P.1
Wiebe, S.A.2
Westaway, D.3
Jhamandas, J.4
Dixon, R.A.5
-
60
-
-
84874786893
-
Ginsenoside Rg1 decreases Aβ1-42 level by upregulating PPARc and IDE expression in the hippocampus of a rat model of alzheimer's disease
-
Quan, Q.; Wang, J.; Li, X.; Wang, Y. Ginsenoside Rg1 Decreases Aβ1-42 Level by Upregulating PPARc and IDE Expression in the Hippocampus of a Rat Model of Alzheimer's Disease. PLOS, 2013, 8, e59155.
-
(2013)
PLOS
, vol.8
-
-
Quan, Q.1
Wang, J.2
Li, X.3
Wang, Y.4
-
61
-
-
77649295213
-
Concordant association of insulin degrading enzyme gene (ide) variants with ide mrna aβ and alzheimer's disease
-
Carrasquillo, M.M.; Belbin, O.; Zou, F.; Allen M.; Ertekin-Taner, N.; Ansari, M.; Wilcox, S.L.; Kashino, M.R.; Ma, L.; Younkin, L.H.; Younkin, S.G.; Younkin, C.S.; Dincman, T.A.; Howard, M.E.; Howell, C.C.; Stanton, C.M.; Watson, C.M.; Crump, M.; Vitart, V.; Hayward, C.; Hastie, N.D.; Rudan, I.; Campbell, H.; Polasek, O.; Brown, K.; Passmore, P.; Craig, D.; McGuiness, B.; Todd, S.; Kehoe, P.G.; Mann, D.M.; Smith, A.D.; Beaumont, H.; Warden, D.; Holmes, C.; Heun, R.; Kölsch, H.; Kalsheker, N.; Pankratz, V.S.; Dickson, D.W.; Graff-Radford, N.R.; Petersen, R.C.; Wright, A.F.; Youunkin, S.G.; Morgan, K. Concordant Association of Insulin Degrading Enzyme Gene (IDE) Variants with IDE mRNA, Aβ, and Alzheimer's Disease. PLOS, 2010, 5, e8764.
-
(2010)
PLOS
, vol.5
-
-
Carrasquillo, M.M.1
Belbin, O.2
Zou, F.3
Allen, M.4
Ertekin-Taner, N.5
Ansari, M.6
Wilcox, S.L.7
Kashino, M.R.8
Ma, L.9
Younkin, L.H.10
Younkin, S.G.11
Younkin, C.S.12
Dincman, T.A.13
Howard, M.E.14
Howell, C.C.15
Stanton, C.M.16
Watson, C.M.17
Crump, M.18
Vitart, V.19
Hayward, C.20
Hastie, N.D.21
Rudan, I.22
Campbell, H.23
Polasek, O.24
Brown, K.25
Passmore, P.26
Craig, D.27
McGuiness, B.28
Todd, S.29
Kehoe, P.G.30
Mann, D.M.31
Smith, A.D.32
Beaumont, H.33
Warden, D.34
Holmes, C.35
Heun, R.36
Kölsch, H.37
Kalsheker, N.38
Pankratz, V.S.39
Dickson, D.W.40
Graff-Radford, N.R.41
Petersen, R.C.42
Wright, A.F.43
Youunkin, S.G.44
Morgan, K.45
more..
-
62
-
-
84871680169
-
Deletion of Crry, the murine ortholog of the sporadic Alzheimer's disease risk gene CR1, impacts tau phosphorylation and brain CFH
-
Killick, R.; Hughes, T. R.; Morgan, B. P.; Lovestone, S. Deletion of Crry, the murine ortholog of the sporadic Alzheimer's disease risk gene CR1, impacts tau phosphorylation and brain CFH. Neurosci. Lett., 2013, 533, 96-99.
-
(2013)
Neurosci. Lett.
, vol.533
, pp. 96-99
-
-
Killick, R.1
Hughes, T.R.2
Morgan, B.P.3
Lovestone, S.4
-
63
-
-
84873673141
-
CR1 and the "vanishing amyloid" hypothesis of alzheimer's disease
-
Gandy, S.; Haroutunian, V.; Dekosky, S. T.; Sano, M.; Schadt, E. E. CR1 and the "Vanishing Amyloid" Hypothesis of Alzheimer's Disease. Biol. Psychiatry, 2013, 73, 393- 95.
-
(2013)
Biol. Psychiatry
, vol.73
, pp. 393-395
-
-
Gandy, S.1
Haroutunian, V.2
Dekosky, S.T.3
Sano, M.4
Schadt, E.E.5
-
64
-
-
1842778936
-
Elevated S-adenosylhomocysteine in Alzheimer brain: Influence on methyltransferases and cognitive function
-
Kennedy, B. P.; Bottiglieri, T.; Arning, E.; Ziegler, M. G.; Hansen, L. A.; Masliah, E. Elevated S-adenosylhomocysteine in Alzheimer brain: influence on methyltransferases and cognitive function. J. Neural. Transm., 2004, 111, 547-567.
-
(2004)
J. Neural. Transm.
, vol.111
, pp. 547-567
-
-
Kennedy, B.P.1
Bottiglieri, T.2
Arning, E.3
Ziegler, M.G.4
Hansen, L.A.5
Masliah, E.6
-
65
-
-
84861739730
-
Catechol-o-methyltransferase and alzheimer's disease: A review of biological and genetic findings
-
Serretti, A.; Olgiati, P. Catechol-O-Methyltransferase and Alzheimer's Disease: A Review of Biological and Genetic Findings. CNS Neurol. Disord. Drug. Targets., 2012, 11, 299-305.
-
(2012)
CNS Neurol. Disord. Drug. Targets.
, vol.11
, pp. 299-305
-
-
Serretti, A.1
Olgiati, P.2
-
66
-
-
84876188924
-
Sexually dimorphic effects of catechol-omethyltransferase (comt) inhibition on dopamine metabolism in multiple brain regions
-
Laatikainen, L. M.; Sharp, T.; Harrison, P. J.; Tunbridge, E. M. Sexually Dimorphic Effects of Catechol-OMethyltransferase (COMT) Inhibition on Dopamine Metabolism in Multiple Brain Regions. PLOS, 2013, 8, e61839.
-
(2013)
PLOS
, vol.8
-
-
Laatikainen, L.M.1
Sharp, T.2
Harrison, P.J.3
Tunbridge, E.M.4
-
67
-
-
77952087072
-
Entacapone Tolcapone Two CatecholO-Methyltransferase Inhibitors Block Fibril Formation of -Synuclein and β-Amyloid and Protect against Amyloid-induced Toxicity
-
Giovanni, S.D.; Eleuteri, S.; Paleologou, K.E.; Yin, G.; Zweckestetter, M.; Carrupt, P-A.; Lashuel, H. A. Entacapone and Tolcapone, Two CatecholO-Methyltransferase Inhibitors, Block Fibril Formation of -Synuclein and β-Amyloid and Protect against Amyloid-induced Toxicity. J. Biol. Chem., 2010, 285, 1491-1495.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 1491-1495
-
-
Giovanni, S.D.1
Eleuteri, S.2
Paleologou, K.E.3
Yin, G.4
Zweckestetter, M.5
Carrupt, P.-A.6
Lashuel, H.A.7
-
68
-
-
36849087430
-
Novel screening assay for antioxidant protection against peroxyl radical- induced loss of protein function
-
Bertolini, F.; Novaroli, L.; Carrupt, P-A.; Reist, M. Novel Screening Assay for Antioxidant Protection against Peroxyl Radical- Induced Loss of Protein Function. J. Pharm. Sci., 2006, 96, 2931- 2944.
-
(2006)
J. Pharm. Sci.
, vol.96
, pp. 2931-2944
-
-
Bertolini, F.1
Novaroli, L.2
Carrupt, P.-A.3
Reist, M.4
-
69
-
-
77149157824
-
Genetics of psychosis in alzheimer disease: A Review
-
DeMichele-Sweet, M.A.; Sweet, R.A. Genetics of Psychosis in Alzheimer Disease: A Review. J. Alzheimers Dis., 2010, 19, 761-780.
-
(2010)
J. Alzheimers Dis.
, vol.19
, pp. 761-780
-
-
Demichele-Sweet, M.A.1
Sweet, R.A.2
|