메뉴 건너뛰기




Volumn 35, Issue 1, 2014, Pages 277-286

YKL-40 expression could be a poor prognostic marker in the breast cancer tissue

Author keywords

Breast cancer; Prognostic marker; YKL 40

Indexed keywords

ALDEHYDE DEHYDROGENASE; CYTOKERATIN 5; CYTOKERATIN 6; EPIDERMAL GROWTH FACTOR RECEPTOR; EPIDERMAL GROWTH FACTOR RECEPTOR 2; ESTROGEN RECEPTOR; GLYCOPROTEIN; KI 67 ANTIGEN; PROGESTERONE RECEPTOR; PROTEIN P53; TRANSCRIPTION FACTOR GLI1; TRANSFORMING GROWTH FACTOR BETA; TUMOR MARKER; UNCLASSIFIED DRUG; YKL 40 GLYCOPROTEIN;

EID: 84893721278     PISSN: 10104283     EISSN: 14230380     Source Type: Journal    
DOI: 10.1007/s13277-013-1036-0     Document Type: Article
Times cited : (19)

References (41)
  • 2
    • 37049183697 scopus 로고
    • Human breast cancer: Correlation of relapse and survival with amplification of the HER-2/neu oncogene
    • 1:CAS:528:DyaL2sXhtVSht7s%3D 3798106 10.1126/science.3798106
    • Slamon DJ, Clark GM, Wong SG, et al. Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene. Science. 1987;235:177-82.
    • (1987) Science , vol.235 , pp. 177-182
    • Slamon, D.J.1    Clark, G.M.2    Wong, S.G.3
  • 3
    • 0027430967 scopus 로고
    • A new biochemical marker for joint injury. Analysis of YKL-40 in serum and synovial fluid
    • 1:STN:280:DyaK2c%2FjsF2nuw%3D%3D 8220933 10.1093/rheumatology/32.11.949
    • Johansen JS, Jensen HS, Price PA. A new biochemical marker for joint injury. Analysis of YKL-40 in serum and synovial fluid. Br J Rheumatol. 1993;32:949-55.
    • (1993) Br J Rheumatol , vol.32 , pp. 949-955
    • Johansen, J.S.1    Jensen, H.S.2    Price, P.A.3
  • 4
    • 0027505001 scopus 로고
    • Human cartilage gp-39, a major secretory product of articular chondrocytes and synovial cells, is a mammalian member of a chitinase protein family
    • 1:CAS:528:DyaK3sXmsVKgtbc%3D 8245017
    • Hakala BE, White C, Recklies AD. Human cartilage gp-39, a major secretory product of articular chondrocytes and synovial cells, is a mammalian member of a chitinase protein family. J Biol Chem. 1993;268:25803-10.
    • (1993) J Biol Chem , vol.268 , pp. 25803-25810
    • Hakala, B.E.1    White, C.2    Recklies, A.D.3
  • 5
    • 0032518453 scopus 로고    scopus 로고
    • Chitotriosidase, a chitinase, and the 39-kDa human cartilage glycoprotein, a chitin-binding lectin, are homologues of family 18 glycosyl hydrolases secreted by human macrophages
    • 1:CAS:528:DyaK1cXnvFSisQ%3D%3D 9492324 10.1046/j.1432-1327.1998.2510504.x
    • Renkema GH, Boot RG, Au FL, et al. Chitotriosidase, a chitinase, and the 39-kDa human cartilage glycoprotein, a chitin-binding lectin, are homologues of family 18 glycosyl hydrolases secreted by human macrophages. Eur J Biochem. 1998;251:504-9.
    • (1998) Eur J Biochem , vol.251 , pp. 504-509
    • Renkema, G.H.1    Boot, R.G.2    Au, F.L.3
  • 6
    • 0141621106 scopus 로고    scopus 로고
    • Crystal structure and carbohydrate-binding properties of the human cartilage glycoprotein-39
    • 1:CAS:528:DC%2BD3sXnsV2lt78%3D 12851408 10.1074/jbc.M303137200
    • Fusetti F, Pijning T, Kalk KH, et al. Crystal structure and carbohydrate-binding properties of the human cartilage glycoprotein-39. J Biol Chem. 2003;278:37753-60.
    • (2003) J Biol Chem , vol.278 , pp. 37753-37760
    • Fusetti, F.1    Pijning, T.2    Kalk, K.H.3
  • 7
    • 0026773679 scopus 로고
    • Identification of proteins secreted by human osteoblastic cells in culture
    • 1:CAS:528:DyaK38XltVyktbs%3D 1615759 10.1002/jbmr.5650070506
    • Johansen JS, Williamson MK, Rice JS, Price PA. Identification of proteins secreted by human osteoblastic cells in culture. J Bone Miner Res. 1992;7:501-12.
    • (1992) J Bone Miner Res , vol.7 , pp. 501-512
    • Johansen, J.S.1    Williamson, M.K.2    Rice, J.S.3    Price, P.A.4
  • 8
    • 17744375604 scopus 로고    scopus 로고
    • Regulation of YKL-40 expression during genotoxic or microenvironmental stress in human glioblastoma cells
    • 1:CAS:528:DC%2BD2MXjsFWgtL8%3D 15771622 10.1111/j.1349-7006.2005.00026.x
    • Junker N, Johansen JS, Hansen LT, et al. Regulation of YKL-40 expression during genotoxic or microenvironmental stress in human glioblastoma cells. Cancer Sci. 2005;96:183-90.
    • (2005) Cancer Sci , vol.96 , pp. 183-190
    • Junker, N.1    Johansen, J.S.2    Hansen, L.T.3
  • 9
    • 0035028329 scopus 로고    scopus 로고
    • Studies on YKL-40 in knee joints of patients with rheumatoid arthritis and osteoarthritis. Involvement of YKL-40 in the joint pathology
    • 1:STN:280:DC%2BD3MzisFWitA%3D%3D 11300743 10.1053/joca.2000.0377
    • Volck B, Johansen JS, Stoltenberg M, et al. Studies on YKL-40 in knee joints of patients with rheumatoid arthritis and osteoarthritis. Involvement of YKL-40 in the joint pathology. Osteoarthr Cartil. 2001;9:203-14.
    • (2001) Osteoarthr Cartil , vol.9 , pp. 203-214
    • Volck, B.1    Johansen, J.S.2    Stoltenberg, M.3
  • 10
    • 0032975495 scopus 로고    scopus 로고
    • Strong induction of members of the chitinase family of proteins in atherosclerosis: Chitotriosidase and human cartilage gp-39 expressed in lesion macrophages
    • 1:CAS:528:DyaK1MXitFGnsb0%3D 10073974 10.1161/01.ATV.19.3.687
    • Boot RG, van Achterberg TA, van Aken BE, et al. Strong induction of members of the chitinase family of proteins in atherosclerosis: chitotriosidase and human cartilage gp-39 expressed in lesion macrophages. Arterioscler Thromb Vasc Biol. 1999;19:687-94.
    • (1999) Arterioscler Thromb Vasc Biol , vol.19 , pp. 687-694
    • Boot, R.G.1    Van Achterberg, T.A.2    Van Aken, B.E.3
  • 11
    • 0033513295 scopus 로고    scopus 로고
    • YKL-40 in giant cells and macrophages from patients with giant cell arteritis
    • 1:CAS:528:DC%2BD3cXjslanug%3D%3D 10616010 10.1002/1529-0131(199912)42: 12<2624: AID-ANR17>3.0.CO;2-K
    • Johansen JS, Baslund B, Garbarsch C, et al. YKL-40 in giant cells and macrophages from patients with giant cell arteritis. Arthritis Rheum. 1999;42:2624-30.
    • (1999) Arthritis Rheum , vol.42 , pp. 2624-2630
    • Johansen, J.S.1    Baslund, B.2    Garbarsch, C.3
  • 12
    • 58149308830 scopus 로고    scopus 로고
    • YKL-40 is elevated in patients with chronic obstructive pulmonary disease and activates alveolar macrophages
    • 1:CAS:528:DC%2BD1cXhtFaru7rF 18802121
    • Letuve S, Kozhich A, Arouche N, et al. YKL-40 is elevated in patients with chronic obstructive pulmonary disease and activates alveolar macrophages. J Immunol. 2008;181:5167-73.
    • (2008) J Immunol , vol.181 , pp. 5167-5173
    • Letuve, S.1    Kozhich, A.2    Arouche, N.3
  • 13
    • 61849086267 scopus 로고    scopus 로고
    • YKL-40, a marker of inflammation and endothelial dysfunction, is elevated in patients with type 1 diabetes and increases with levels of albuminuria
    • 1:CAS:528:DC%2BD1MXis1WrsL4%3D 18957531 10.2337/dc08-1144
    • Rathcke CN, Persson F, Tarnow L, et al. YKL-40, a marker of inflammation and endothelial dysfunction, is elevated in patients with type 1 diabetes and increases with levels of albuminuria. Diabetes Care. 2009;32:323-8.
    • (2009) Diabetes Care , vol.32 , pp. 323-328
    • Rathcke, C.N.1    Persson, F.2    Tarnow, L.3
  • 14
    • 36148981436 scopus 로고    scopus 로고
    • A chitinase-like protein in the lung and circulation of patients with severe asthma
    • 1:CAS:528:DC%2BD2sXhtlWis7rO 18003958 10.1056/NEJMoa073600
    • Chupp GL, Lee CG, Jarjour N, et al. A chitinase-like protein in the lung and circulation of patients with severe asthma. N Engl J Med. 2007;357:2016-27.
    • (2007) N Engl J Med , vol.357 , pp. 2016-2027
    • Chupp, G.L.1    Lee, C.G.2    Jarjour, N.3
  • 15
    • 0036645699 scopus 로고    scopus 로고
    • The chitinase 3-like protein human cartilage glycoprotein 39 (HC-gp39) stimulates proliferation of human connective-tissue cells and activates both extracellular signal-regulated kinase- and protein kinase B-mediated signalling pathways
    • 1:CAS:528:DC%2BD38XlsV2htbs%3D 12071845 10.1042/BJ20020075
    • Recklies AD, White C, Ling H. The chitinase 3-like protein human cartilage glycoprotein 39 (HC-gp39) stimulates proliferation of human connective-tissue cells and activates both extracellular signal-regulated kinase- and protein kinase B-mediated signalling pathways. Biochem J. 2002;365:119-26.
    • (2002) Biochem J , vol.365 , pp. 119-126
    • Recklies, A.D.1    White, C.2    Ling, H.3
  • 16
    • 0033542726 scopus 로고    scopus 로고
    • Gp38k, a protein synthesized by vascular smooth muscle cells, stimulates directional migration of human umbilical vein endothelial cells
    • 1:CAS:528:DyaK1MXktV2ktro%3D 10388530 10.1006/excr.1999.4511
    • Malinda KM, Ponce L, Kleinman HK, et al. Gp38k, a protein synthesized by vascular smooth muscle cells, stimulates directional migration of human umbilical vein endothelial cells. Exp Cell Res. 1999;250:168-73.
    • (1999) Exp Cell Res , vol.250 , pp. 168-173
    • Malinda, K.M.1    Ponce, L.2    Kleinman, H.K.3
  • 17
    • 0037530029 scopus 로고    scopus 로고
    • Gp38k (CHI3L1) is a novel adhesion and migration factor for vascular cells
    • 1:CAS:528:DC%2BD3sXksVyrtbs%3D 12799184 10.1016/S0014-4827(03)00069-7
    • Nishikawa KC, Millis AJ. gp38k (CHI3L1) is a novel adhesion and migration factor for vascular cells. Exp Cell Res. 2003;287:79-87.
    • (2003) Exp Cell Res , vol.287 , pp. 79-87
    • Nishikawa, K.C.1    Millis, A.J.2
  • 18
    • 0037180757 scopus 로고    scopus 로고
    • Inflammation and cancer
    • 1:CAS:528:DC%2BD38XpsFygtb4%3D 2803035 12490959 10.1038/nature01322
    • Coussens LM, Werb Z. Inflammation and cancer. Nature. 2002;420:860-7.
    • (2002) Nature , vol.420 , pp. 860-867
    • Coussens, L.M.1    Werb, Z.2
  • 19
    • 0037485763 scopus 로고    scopus 로고
    • High serum YKL-40 levels in patients with primary breast cancer is related to short recurrence free survival
    • 1:CAS:528:DC%2BD3sXkvVCksLY%3D 12889595 10.1023/A:1024431000710
    • Johansen JS, Christensen IJ, Riisbro R, et al. High serum YKL-40 levels in patients with primary breast cancer is related to short recurrence free survival. Breast Cancer Res Treat. 2003;80:15-21.
    • (2003) Breast Cancer Res Treat , vol.80 , pp. 15-21
    • Johansen, J.S.1    Christensen, I.J.2    Riisbro, R.3
  • 20
    • 0029094048 scopus 로고
    • Serum YKL-40: A new potential marker of prognosis and location of metastases of patients with recurrent breast cancer
    • 1:CAS:528:DyaK2MXosl2rs7Y%3D 7577068 10.1016/0959-8049(95)00196-P
    • Johansen JS, Cintin C, Jorgensen M, et al. Serum YKL-40: a new potential marker of prognosis and location of metastases of patients with recurrent breast cancer. Eur J Cancer. 1995;31A:1437-42.
    • (1995) Eur J Cancer , vol.31 , pp. 1437-1442
    • Johansen, J.S.1    Cintin, C.2    Jorgensen, M.3
  • 21
    • 0037099560 scopus 로고    scopus 로고
    • High serum YKL-40 level after surgery for colorectal carcinoma is related to short survival
    • 12124825 10.1002/cncr.10644
    • Cintin C, Johansen JS, Christensen IJ, et al. High serum YKL-40 level after surgery for colorectal carcinoma is related to short survival. Cancer. 2002;95:267-74.
    • (2002) Cancer , vol.95 , pp. 267-274
    • Cintin, C.1    Johansen, J.S.2    Christensen, I.J.3
  • 22
    • 0141960434 scopus 로고    scopus 로고
    • High levels of serum HER-2/neu and YKL-40 independently reflect aggressiveness of metastatic breast cancer
    • 1:CAS:528:DC%2BD3sXotVShsbg%3D 14555515
    • Jensen BV, Johansen JS, Price PA. High levels of serum HER-2/neu and YKL-40 independently reflect aggressiveness of metastatic breast cancer. Clin Cancer Res. 2003;9:4423-34.
    • (2003) Clin Cancer Res , vol.9 , pp. 4423-4434
    • Jensen, B.V.1    Johansen, J.S.2    Price, P.A.3
  • 23
    • 0037361965 scopus 로고    scopus 로고
    • Plasma YKL-40, as a prognostic tumor marker in recurrent ovarian cancer
    • 12694127 10.1034/j.1600-0412.2003.00010.x
    • Dehn H, Hogdall EV, Johansen JS, et al. Plasma YKL-40, as a prognostic tumor marker in recurrent ovarian cancer. Acta Obstet Gynecol Scand. 2003;82:287-93.
    • (2003) Acta Obstet Gynecol Scand , vol.82 , pp. 287-293
    • Dehn, H.1    Hogdall, E.V.2    Johansen, J.S.3
  • 24
    • 8444236654 scopus 로고    scopus 로고
    • High serum YKL-40 level in patients with small cell lung cancer is related to early death
    • 15541818 10.1016/j.lungcan.2004.05.010
    • Johansen JS, Drivsholm L, Price PA, Christensen IJ. High serum YKL-40 level in patients with small cell lung cancer is related to early death. Lung Cancer. 2004;46:333-40.
    • (2004) Lung Cancer , vol.46 , pp. 333-340
    • Johansen, J.S.1    Drivsholm, L.2    Price, P.A.3    Christensen, I.J.4
  • 25
    • 33644534470 scopus 로고    scopus 로고
    • Elevated serum level of YKL-40 is an independent prognostic factor for poor survival in patients with metastatic melanoma
    • 1:CAS:528:DC%2BD28Xis1agt7c%3D 16456816 10.1002/cncr.21678
    • Schmidt H, Johansen JS, Gehl J, et al. Elevated serum level of YKL-40 is an independent prognostic factor for poor survival in patients with metastatic melanoma. Cancer. 2006;106:1130-9.
    • (2006) Cancer , vol.106 , pp. 1130-1139
    • Schmidt, H.1    Johansen, J.S.2    Gehl, J.3
  • 26
    • 33846684089 scopus 로고    scopus 로고
    • YKL-40 expression in benign and malignant lesions of the breast: A methodologic study
    • 1:CAS:528:DC%2BD2sXhsVyhurzP 18091378 10.1097/01.pai.0000213146.77772.6a
    • Roslind A, Johansen JS, Junker N, et al. YKL-40 expression in benign and malignant lesions of the breast: a methodologic study. Appl Immunohistochem Mol Morphol. 2007;15:371-81.
    • (2007) Appl Immunohistochem Mol Morphol , vol.15 , pp. 371-381
    • Roslind, A.1    Johansen, J.S.2    Junker, N.3
  • 27
    • 83055191301 scopus 로고    scopus 로고
    • YKL-40 expression in human hepatocellular carcinoma: A potential biomarker?
    • 22146624 10.1016/S1499-3872(11)60103-3
    • Xiao XQ, Hassanein T, Li QF, et al. YKL-40 expression in human hepatocellular carcinoma: a potential biomarker? Hepatobiliary Pancreat Dis Int. 2011;10:605-10.
    • (2011) Hepatobiliary Pancreat Dis Int , vol.10 , pp. 605-610
    • Xiao, X.Q.1    Hassanein, T.2    Li, Q.F.3
  • 28
    • 77956056197 scopus 로고    scopus 로고
    • Prognostic significance of histological grading, p53 status, YKL-40 expression, and IDH1 mutations in pediatric high-grade gliomas
    • 1:CAS:528:DC%2BC3cXhtVGmtLfI 20174854 10.1007/s11060-010-0129-5
    • Antonelli M, Buttarelli FR, Arcella A, et al. Prognostic significance of histological grading, p53 status, YKL-40 expression, and IDH1 mutations in pediatric high-grade gliomas. J Neurooncol. 2010;99:209-15.
    • (2010) J Neurooncol , vol.99 , pp. 209-215
    • Antonelli, M.1    Buttarelli, F.R.2    Arcella, A.3
  • 29
    • 70349786795 scopus 로고    scopus 로고
    • Expression of the glioma-associated oncogene homolog (GLI) 1 in human breast cancer is associated with unfavourable overall survival
    • 2753634 19706168 10.1186/1471-2407-9-298
    • ten Haaf A, Bektas N, von Serenyi S, et al. Expression of the glioma-associated oncogene homolog (GLI) 1 in human breast cancer is associated with unfavourable overall survival. BMC Cancer. 2009;9:298.
    • (2009) BMC Cancer , vol.9 , pp. 298
    • Ten Haaf, A.1    Bektas, N.2    Von Serenyi, S.3
  • 30
    • 79952711817 scopus 로고    scopus 로고
    • Aldehyde dehydrogenase 1 expression is a predictor of poor prognosis in node-positive breast cancers: A long-term follow-up study
    • 21371077 10.1111/j.1365-2559.2011.03781.x
    • Yoshioka T, Umekita Y, Ohi Y, et al. Aldehyde dehydrogenase 1 expression is a predictor of poor prognosis in node-positive breast cancers: a long-term follow-up study. Histopathology. 2011;58:608-16.
    • (2011) Histopathology , vol.58 , pp. 608-616
    • Yoshioka, T.1    Umekita, Y.2    Ohi, Y.3
  • 31
    • 31444442248 scopus 로고    scopus 로고
    • Determination of TGFbeta1 protein level in human primary breast cancers and its relationship with survival
    • 1:CAS:528:DC%2BD28XmvVygtQ%3D%3D 2361106 16404434 10.1038/sj.bjc.6602920
    • Desruisseau S, Palmari J, Giusti C, et al. Determination of TGFbeta1 protein level in human primary breast cancers and its relationship with survival. Br J Cancer. 2006;94:239-46.
    • (2006) Br J Cancer , vol.94 , pp. 239-246
    • Desruisseau, S.1    Palmari, J.2    Giusti, C.3
  • 32
    • 33846568336 scopus 로고    scopus 로고
    • American Society of Clinical Oncology/College of American Pathologists guideline recommendations for human epidermal growth factor receptor 2 testing in breast cancer
    • 1:CAS:528:DC%2BD2sXhsVOmu74%3D 19548375
    • Wolff AC, Hammond ME, Schwartz JN, et al. American Society of Clinical Oncology/College of American Pathologists guideline recommendations for human epidermal growth factor receptor 2 testing in breast cancer. Arch Pathol Lab Med. 2007;131:18-43.
    • (2007) Arch Pathol Lab Med , vol.131 , pp. 18-43
    • Wolff, A.C.1    Hammond, M.E.2    Schwartz, J.N.3
  • 33
    • 33847660092 scopus 로고    scopus 로고
    • Prognostic implications of immunohistochemically detected YKL-40 expression in breast cancer
    • 1802867 17286869 10.1186/1477-7819-5-17
    • Kim SH, Das K, Noreen S, et al. Prognostic implications of immunohistochemically detected YKL-40 expression in breast cancer. World J Surg Oncol. 2007;5:17.
    • (2007) World J Surg Oncol , vol.5 , pp. 17
    • Kim, S.H.1    Das, K.2    Noreen, S.3
  • 34
    • 53949093693 scopus 로고    scopus 로고
    • YKL-40 protein expression is not a prognostic marker in patients with primary breast cancer
    • 1:CAS:528:DC%2BD1cXht1Cms73M 18157633 10.1007/s10549-007-9870-7
    • Roslind A, Knoop AS, Jensen MB, et al. YKL-40 protein expression is not a prognostic marker in patients with primary breast cancer. Breast Cancer Res Treat. 2008;112:275-85.
    • (2008) Breast Cancer Res Treat , vol.112 , pp. 275-285
    • Roslind, A.1    Knoop, A.S.2    Jensen, M.B.3
  • 35
    • 80053970009 scopus 로고    scopus 로고
    • Breast cancer expression of YKL-40 correlates with tumour grade, poor differentiation, and other cancer markers
    • 1:CAS:528:DC%2BC3MXhtlahsrrK 3208489 21934681 10.1038/bjc.2011.347
    • Shao R, Cao QJ, Arenas RB, et al. Breast cancer expression of YKL-40 correlates with tumour grade, poor differentiation, and other cancer markers. Br J Cancer. 2011;105:1203-9.
    • (2011) Br J Cancer , vol.105 , pp. 1203-1209
    • Shao, R.1    Cao, Q.J.2    Arenas, R.B.3
  • 36
    • 58749083936 scopus 로고    scopus 로고
    • Serum YKL-40 levels as a prognostic factor in patients with locally advanced breast cancer
    • 18670741 10.1007/s12325-008-0082-2
    • Yamac D, Ozturk B, Coskun U, et al. Serum YKL-40 levels as a prognostic factor in patients with locally advanced breast cancer. Adv Ther. 2008;25:801-9.
    • (2008) Adv Ther , vol.25 , pp. 801-809
    • Yamac, D.1    Ozturk, B.2    Coskun, U.3
  • 37
    • 84865152701 scopus 로고    scopus 로고
    • The roles of TGF-beta signaling in carcinogenesis and breast cancer metastasis
    • 22139728 10.1007/s12282-011-0321-2
    • Imamura T, Hikita A, Inoue Y. The roles of TGF-beta signaling in carcinogenesis and breast cancer metastasis. Breast Cancer. 2012;19:118-24.
    • (2012) Breast Cancer , vol.19 , pp. 118-124
    • Imamura, T.1    Hikita, A.2    Inoue, Y.3
  • 38
    • 40949137792 scopus 로고    scopus 로고
    • Sonic hedgehog signaling promotes motility and invasiveness of gastric cancer cells through TGF-beta-mediated activation of the ALK5-Smad 3 pathway
    • 1:CAS:528:DC%2BD1cXjsVamsLc%3D 18174246 10.1093/carcin/bgm281
    • Yoo YA, Kang MH, Kim JS, Oh SC. Sonic hedgehog signaling promotes motility and invasiveness of gastric cancer cells through TGF-beta-mediated activation of the ALK5-Smad 3 pathway. Carcinogenesis. 2008;29:480-90.
    • (2008) Carcinogenesis , vol.29 , pp. 480-490
    • Yoo, Y.A.1    Kang, M.H.2    Kim, J.S.3    Oh, S.C.4
  • 39
    • 34547120220 scopus 로고    scopus 로고
    • Induction of sonic hedgehog mediators by transforming growth factor-beta: Smad3-dependent activation of Gli2 and Gli1 expression in vitro and in vivo
    • 1:CAS:528:DC%2BD2sXnslOit7c%3D 17638910 10.1158/0008-5472.CAN-07-0491
    • Dennler S, Andre J, Alexaki I, et al. Induction of sonic hedgehog mediators by transforming growth factor-beta: Smad3-dependent activation of Gli2 and Gli1 expression in vitro and in vivo. Cancer Res. 2007;67:6981-6.
    • (2007) Cancer Res , vol.67 , pp. 6981-6986
    • Dennler, S.1    Andre, J.2    Alexaki, I.3
  • 40
    • 79956057857 scopus 로고    scopus 로고
    • A YKL-40-neutralizing antibody blocks tumor angiogenesis and progression: A potential therapeutic agent in cancers
    • 1:CAS:528:DC%2BC3MXlslKgtr0%3D 3091949 21357475 10.1158/1535-7163.MCT-10- 0868
    • Faibish M, Francescone R, Bentley B, et al. A YKL-40-neutralizing antibody blocks tumor angiogenesis and progression: a potential therapeutic agent in cancers. Mol Cancer Ther. 2011;10:742-51.
    • (2011) Mol Cancer Ther , vol.10 , pp. 742-751
    • Faibish, M.1    Francescone, R.2    Bentley, B.3
  • 41
    • 35448956544 scopus 로고    scopus 로고
    • Locally advanced breast carcinoma treated with neoadjuvant chemotherapy: Are the changes in serum levels of YKL-40, MMP-2 and MMP-9 correlated with tumor response?
    • 1:CAS:528:DC%2BD1cXhs1aqtA%3D%3D 17845129
    • Coskun U, Yamac D, Gulbahar O, et al. Locally advanced breast carcinoma treated with neoadjuvant chemotherapy: are the changes in serum levels of YKL-40, MMP-2 and MMP-9 correlated with tumor response? Neoplasma. 2007;54:348-52.
    • (2007) Neoplasma , vol.54 , pp. 348-352
    • Coskun, U.1    Yamac, D.2    Gulbahar, O.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.