The inverted CD4:CD8 ratio is associated with cytomegalovirus, poor cognitive and functional states in older adults

NeuroImmunoModulation

Volumn 21, Issue 4, 2014, Pages 206-212

  Luz Correa, Bruna ^a   Ornaghi, Ana Paula ^a   Cerutti Muller, Guilherme ^a   Engroff, Paula ^a   Pestana Lopes, Rodrigo ^c   Gomes Da Silva Filho, Irênio ^a   Bosch, Jos A ^d   Bonorino, Cristina ^b   Bauer, Moisés Evandro ^a  

^a PONTIFICAL CATHOLIC UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

^b Institute of Biomedical Research   (Spain)

^c BD Biosciences   (Brazil)

^d UNIVERSITY OF BIRMINGHAM   (United Kingdom)

Author keywords

CD4:CD8 ratio; Cognitive function; Cytomegalovirus; Immunosenescence; Lymphocytes; T cells

Indexed keywords

CYTOMEGALOVIRUS ANTIBODY; IMMUNOGLOBULIN G ANTIBODY; CD28 ANTIGEN; CD4 ANTIGEN; CD8 ANTIGEN;

ADULT; AGED; AGING; ANTIBODY TITER; ARTICLE; B LYMPHOCYTE; CD4 CD8 RATIO; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; COGNITIVE DEFECT; CYTOMEGALOVIRUS INFECTION; DAILY LIFE ACTIVITY; DEVELOPING COUNTRY; DISABILITY; ENZYME LINKED IMMUNOSORBENT ASSAY; EPSTEIN BARR VIRUS INFECTION; FEMALE; FLOW CYTOMETRY; FUNCTIONAL STATUS; HUMAN; IMMUNOPHENOTYPING; IMMUNOSENESCENCE; INSTRUMENT OF BRIEF NEUROPSYCHOLOGICAL ASSESSMENT; MAJOR CLINICAL STUDY; MALE; MIDDLE AGED; NATURAL KILLER CELL; NATURAL KILLER T CELL; NEUROPSYCHOLOGICAL TEST; PERIPHERAL LYMPHOCYTE; PERSISTENT VIRUS INFECTION; PFEFFER FUNCTIONAL ACTIVITIES QUESTIONNAIRE; PRIORITY JOURNAL; QUESTIONNAIRE; SEROLOGY; T LYMPHOCYTE SUBPOPULATION; VERY ELDERLY; ASSESSMENT OF HUMANS; BRIEF NEUROPSYCHOLOGICAL ASSESSMENT; COGNITION; CYTOMEGALOVIRUS; EPSTEIN BARR VIRUS; MINI MENTAL STATE EXAMINATION; MORBIDITY; MORTALITY;

AGED; AGED, 80 AND OVER; AGING; CD4-CD8 RATIO; COGNITION; CYTOMEGALOVIRUS INFECTIONS; FEMALE; FLOW CYTOMETRY; HUMANS; IMMUNOPHENOTYPING; MALE; MIDDLE AGED; NEUROPSYCHOLOGICAL TESTS;

EID: 84893700021     PISSN: 10217401     EISSN: 14230216     Source Type: Journal    
DOI: 10.1159/000356827     Document Type: Article

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