Immunohistochemical analysis of metaplastic non-goblet columnar lined oesophagus shows phenotypic similarities to Barrett's oesophagus: A study in an Asian population

Digestive and Liver Disease

Volumn 46, Issue 2, 2014, Pages 170-175

  Srivastava, Supriya ^a   Liew, Mei Shan ^b   McKeon, Frank ^b,c   Xian, Wa ^d,e   Yeoh, Khay Guan ^f   Ho, Khek Yu ^f   Teh, Ming ^f  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^b GENOME INSTITUTE OF SINGAPORE   (Singapore)

^c HARVARD MEDICAL SCHOOL   (United States)

^d BRIGHAM AND WOMEN S HOSPITAL   (United States)

^e INSTITUTE OF MEDICAL BIOLOGY   (Singapore)

^f NATIONAL UNIVERSITY HEALTH SYSTEM   (Singapore)

Author keywords

Barrett's oesophagus; Claudin 3; Columnar lined oesophagus; MUC4; Oesophageal adenocarcinoma

Indexed keywords

CLAUDIN 3; MUCIN 4; VILLIN;

ADULT; AGED; ARTICLE; ASIAN; BARRETT ESOPHAGUS; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATIONAL STUDY; DISEASE ASSOCIATION; ENDOSCOPIC BIOPSY; ESOPHAGEAL ADENOCARCINOMA; ESOPHAGOSCOPY; ESOPHAGUS DISEASE; ESOPHAGUS DYSPLASIA; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MALE; MIDDLE AGED; NON GOBLET COLUMNAR LINED ESOPHAGUS; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; YOUNG ADULT;

BARRETT'S OESOPHAGUS; CLAUDIN 3; COLUMNAR LINED OESOPHAGUS; MUC4; OESOPHAGEAL ADENOCARCINOMA;

ADENOCARCINOMA; ADULT; AGED; AGED, 80 AND OVER; ASIAN CONTINENTAL ANCESTRY GROUP; BARRETT ESOPHAGUS; CLAUDIN-3; EPITHELIAL CELLS; ESOPHAGEAL NEOPLASMS; FEMALE; GOBLET CELLS; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MICROFILAMENT PROTEINS; MIDDLE AGED; MUCIN-4; PHENOTYPE;

EID: 84893693667     PISSN: 15908658     EISSN: 18783562     Source Type: Journal    
DOI: 10.1016/j.dld.2013.09.025     Document Type: Article

References (40)

1. Werner M., Flejou J.F., Hainaut P., et al. Tumours of the oesophagus. WHO classification of tumours, pathology & genetics, tumors of the digestive system 2000, 20-36. IARC Press, Lyon, France. S.R. Hamilton, L.A. Aaltonen (Eds.).
2. Wang K.K., Sampliner R.E. Practice Parameters Committee of the American College of Gastroenterology: updated guidelines 2008 for the diagnosis, surveillance and therapy of Barrett's oesophagus. American Journal of Gastroenterology 2008, 103:788-797.
3. Playford R.J. New British Society of Gastroenterology (BSG) guidelines for the diagnosis and management of Barrett's oesophagus. Gut 2006, 55:442-443.
4. Ogiya K., Kawano T., Ito E., et al. Lower oesophageal palisade vessels and the definition of Barrett's oesophagus. Diseases of the Oesophagus 2008, 21:645-649.
5. Peng S., Xiong L.S., Xiao Y.L., et al. Prompt upper endoscopy is an appropriate initial management in uninvestigated Chinese patients with typical reflux symptoms. American Journal of Gastroenterology 2010, 105:1947-1952.
6. Kim J.Y., Kim Y.S., Jung M.K., et al. Prevalence of Barrett's oesophagus in Korea. Journal of Gastroenterology and Hepatology 2005, 20:633-636.
7. Chandrasoma P.T., Deer R., Dalton P., et al. Distribution and significance of epithelial types in columnar-lined oesophagus. American Journal of Surgical Pathology 2001, 25:1188-1193.
8. Yousef F., Cardwell C., Cantwell M.M., et al. The incidence of oesophageal cancer and high-grade dysplasia in Barrett's oesophagus: a systematic review and meta-analysis. American Journal of Epidemiology 2008, 168:237-249.
9. Bollschweiler E., Wolfgarten E., Gutschow C., et al. Demographic variations in the rising incidence of oesophageal adenocarcinoma in white males. Cancer 2001, 92:549-555.
10. Fernandes M.L., Seow A., Chan Y.H., et al. Opposing trends in incidence of oesophageal squamous cell carcinoma and adenocarcinoma in a multi-ethnic Asian country. American Journal of Gastroenterology 2006, 101:1430-1436.
11. Shibata A., Matsuda T., Ajiki W., et al. Trend in incidence of adenocarcinoma of the oesophagus in Japan, 1993-2001. Japanese Journal of Clinical Oncology 2008, 38:464-468.
12. Haghdoost A.A., Hosseini H., Chamani G., et al. Rising incidence of adenocarcinoma of the oesophagus in Kerman, Iran. Archives of Iranian Medicine 2008, 11:364-370.
13. Gatenby P.C., Ramus J.R., Caygill C.P., et al. Relevance of the detection of intestinal metaplasia in non-dysplastic columnar-lined oesophagus. Scandinavian Journal of Gastroenterology 2008, 43:524-530.
14. Kelty C.J., Gough M.D., Wyk Q.V., et al. Barrett's oesophagus: intestinal metaplasia is not essential for cancer risk. Scandinavian Journal of Gastroenterology 2007, 42:1271-1274.
15. Corfield A.P., Carroll D., Myerscough N., et al. Mucins in the gastrointestinal tract in health and disease. Frontiers in Bioscience 2001, 6:D1321-D1357.
16. Piessen G., Jnocheere N., Vincent A., et al. Regulation of the human mucin MUC4 by taurodeoxycholic bile acids in oesophageal cancer cells is mediated by hepatocyte nuclear factor 1 alpha. Biochemical Journal 2007, 402:81-91.
17. Morin P.J. Claudin proteins in human cancer: promising new targets for diagnosis and therapy. Cancer Research 2005, 65:9603-9606.
18. Montgomery E., Mamelak A.J., Gibson, et al. Overexpression of claudin proteins in oesophageal adenocarcinoma and its precursor lesions. Applied Immunohistochemistry and Molecular Morphology 2006, 14:24-30.
19. Meng J., Vardar D., Wang Y., et al. High-resolution crystal structures of villin headpiece and mutants with reduced F-actin binding activity. Biochemistry 2005, 44:11963-11973.
20. Regalado S.P., Nambu Y., Iannettoni M.D., et al. Abundant expression of the intestinal protein villin in Barrett's metaplasia and oesophageal adenocarcinomas. Molecular Carcinogenesis 1998, 22:182-189.
21. Okugawa T., Oshima T., Chen X., et al. Down-regulation of claudin-3 is associated with proliferative potential in early gastric cancer. Digestive Diseases and Sciences 2012, 57:1562-1567.
22. Arul G.S., Moorghen M., Myerscough N., et al. Mucin gene expression in Barrett's oesophagus: an in situ hybridisation and immunohistochemical study. Gut 2000, 47:753-761.
23. Hahn H., Blount P.L., Ayub K., et al. Intestinal differentiation in metaplastic, non-goblet columnar epithelium in the oesophagus. American Journal of Surgical Pathology 2009, 33:1006-1015.
24. Ho K.Y. From GERD to Barrett's oesophagus: is the pattern in Asia mirroring that in the West. Journal of Gastroenterology and Hepatology 2011, 26:816-824.
25. Ishimura N., Amano Y., Sollano J.D., et al. Questionnaire-based survey conducted in 2011 concerning endoscopic management of Barrett's oesophagus in east Asian countries. Digestion 2012, 86:136-146.
26. Law S., Lam K.Y., Chu K.M., et al. Specialized intestinal metaplasia and carditis at the gastroesophageal junction in Chinese patients undergoing endoscopy. American Journal of Gastroenterology 2002, 97:1924-1929.
27. Xiong L.S., Cui Y., Wang J.P., et al. Prevalence and risk factors of Barrett's oesophagus in patients undergoing endoscopy for upper gastrointestinal symptoms. Journal of Digestive Diseases 2010, 11:83-87.
28. Hirst N.G., Gordon L.G., Whiteman D.C., et al. Is endoscopic surveillance for non-dysplastic Barrett's oesophagus cost-effective? Review of economic evaluations. Journal of Gastroenterology and Hepatology 2011, 26:247-254.
29. Weimann A., Rieger A., Zimmermann M., et al. Comparison of six immunohistochemical markers for the histologic diagnosis of neoplasia in Barrett's oesophagus. Virchows Archiv 2010, 457:337-345.
30. Chaves P., Cruz C., Dias Pereira A., et al. Gastric and intestinal differentiation in Barrett's metaplasia and associated adenocarcinoma. Diseases of the Oesophagus 2005, 18:383-387.
31. Bruyère E., Jonckheere N., Frénois F., et al. The MUC4 membrane-bound mucin regulates oesophageal cancer cell proliferation and migration properties: Implication for S100A4 protein. Biochemical and Biophysical Research Communications 2001, 413:325-329.
32. Bax D.A., Haringsma J., Einerhand A.W., et al. MUC4 is increased in high grade intraepithelial neoplasia in Barrett's oesophagus and is associated with a proapoptotic Bax to Bcl-2 ratio. Journal of Clinical Pathology 2004, 57:1267-1272.
33. Guillem P., Billeret V., Buisine M.P., et al. Mucin gene expression and cell differentiation in human premalignant and malignant oesophagus. International Journal of Cancer 2000, 88:856-861.
34. Piessen G., Wacrenier A., Briez N., et al. Clinical impact of MUC1 and MUC4 expression in Barrett-associated oesophageal adenocarcinoma. Journal of Clinical Pathology 2009, 62:1144-1146.
35. Hopwood D., Logan K.R., Coghill G., et al. Histochemical studies of the muco-substances and the lipids in the normal human oesophageal epithelium. Histochemical Journal 1977, 9:153-161.
36. Chandrasoma P., Wijetunge S., DeMeester S., et al. Columnar-lined oesophagus without intestinal metaplasia has no proven risk of adenocarcinoma. American Journal of Surgical Pathology 2012, 36:1-7.
37. Bhat S., Coleman H.G., Yousef F., et al. Risk of malignant progression in Barrett's oesophagus patients: results from a large population-based study. Journal of the National Cancer Institute 2011, 103:1049-1057.
38. Chaves P., Crespo M., Ribeiro C., et al. Chromosomal analysis of Barrett's cells: demonstration of instability and detection of the metaplastic lineage involved. Modern Pathology 2007, 20:788-796.
39. Pereira A.D., Chaves P. Columnar-lined oesophagus without intestinal metaplasia: results from a cohort with a mean follow-up of 7 years. Alimentary Pharmacology and Therapeutics 2012, 36:282-289.
40. Liu W., Hahn H., Odze R., et al. Metaplastic oesophageal columnar epithelium without goblet cells shows DNA content abnormalities similar to goblet cell-containing epithelium. American Journal of Gastroenterology 2009, 104:816-824.