Comparison of six immunohistochemical markers for the histologic diagnosis of neoplasia in Barrett's esophagus

Virchows Archiv

Volumn 457, Issue 5, 2010, Pages 537-545

  Weimann, Andreas ^a   Rieger, Anja ^a   Zimmermann, Mathias ^a   Gross, Monica ^a   Hoffmann, Peter ^a   Slevogt, Hortense ^a   Morawietz, Lars ^a  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

Author keywords

Barrett's esophagus; Immunohistochemistry; Intestinal metaplasia; Intraepithelial neoplasia; LI cadherin; Mucin 2

Indexed keywords

CADHERIN; CLAUDIN 2; L1 CADHERIN; MEMBRANE PROTEIN; MUCIN 2; TRANSCRIPTION FACTOR CDX2; TUMOR MARKER; UNCLASSIFIED DRUG; VILLIN;

ADULT; AGED; ARTICLE; BARRETT ESOPHAGUS; BLOOD GROUP LEWIS SYSTEM; CANCER DIAGNOSIS; CANCER GRADING; COMPARATIVE STUDY; DIFFERENTIAL DIAGNOSIS; ESOPHAGEAL ADENOCARCINOMA; ESOPHAGUS CANCER; ESOPHAGUS RESECTION; FEMALE; HISTOPATHOLOGY; HUMAN; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL;

ADENOCARCINOMA; ADULT; AGED; AGED, 80 AND OVER; BARRETT ESOPHAGUS; CADHERINS; ESOPHAGEAL NEOPLASMS; FEMALE; HOMEODOMAIN PROTEINS; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MEMBRANE PROTEINS; MICROFILAMENT PROTEINS; MIDDLE AGED; MUCIN-2; TUMOR MARKERS, BIOLOGICAL;

EID: 78149467337     PISSN: 09456317     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00428-010-0972-y     Document Type: Article

References (52)

1. NR Barrett 1950 Chronic peptic ulcer of the oesophagus and 'oesophagitis' Br J Surg 38 175 182 10.1002/bjs.18003815005 14791960 1:STN:280: DyaG3M%2FitFGisg%3D%3D
2. NR Barrett 1957 The lower esophagus lined by columnar epithelium Surgery 41 881 894 13442856 1:STN:280:DyaG2s%2FovFGrtA%3D%3D
3. RC Haggitt 1992 Adenocarcinoma in Barrett's esophagus: a new epidemic? Hum Pathol 23 475 476 10.1016/0046-8177(92)90121-I 1568742 1:STN:280: DyaK383jsVCqug%3D%3D
4. G Sarosi G Brown K Jaiswal, et al. 2008 Bone marrow progenitor cells contribute to esophageal regeneration and metaplasia in a rat model of Barrett's esophagus Dis Esophagus 21 43 50 18197938 1:STN:280:DC%2BD1c%2FksVentQ%3D%3D
5. RE Sampliner 1998 Practice guidelines on the diagnosis, surveillance, and therapy of Barrett'sesophagus. The Practice Parameters Committee of the American College of Gastroenterology Am J Gastroenterol 93 1028 1032 10.1111/j.1572-0241.1998.00362.x 9672324 1:STN:280:DyaK1czjs1Slug%3D%3D (Pubitemid 29080944)
6. WM Weinstein AF Ippoliti 1996 The diagnosis of Barrett's esophagus: goblets, goblets, goblets Gastrointest Endosc 44 91 95 10.1016/S0016-5107(96) 70239-0 8836727 1:STN:280:DyaK28vjtlOntQ%3D%3D
7. KP Batts 2001 Barrett esophagus-more steps forward Hum Pathol 32 357 359 10.1053/hupa.2001.24685 11331951 1:STN:280:DC%2BD3Mzis1Sgtg%3D%3D (Pubitemid 32378296)
8. JR Goldblum 2003 Barrett's esophagus and Barrett's-related dysplasia Mod Pathol 16 316 324 10.1097/01.MP.0000062996.66432.12 12692197 (Pubitemid 36443981)
9. WJ Blot SS Devesa RW Kneller JF Fraumeni Jr 1991 Rising incidence of adenocarcinoma of the esophagus and gastric cardia JAMA 265 1287 1289 10.1001/jama.265.10.1287 1995976 1:STN:280:DyaK3M7ktVOqsQ%3D%3D
10. AP Vizcaino V Moreno R Lambert DM Parkin 2002 Time trends incidence of both major histologic types of esophageal carcinomas in selected countries, 1973-1995 Int J Cancer 99 860 868 10.1002/ijc.10427 12115489 1:CAS:528:DC%2BD38XksVajsLw%3D (Pubitemid 34575705)
11. MA Eloubedi D Provenzale 1999 Does this patient have Barrett's esophagus? The utility of predicting Barrett's esophagus at the index endoscopy Am J Gastroenterol 94 937 943 10.1111/j.1572-0241.1999.990-m.x
12. JN Freund C Domon-Dell M Kedinger I Duluc 1998 The Cdx-1 and Cdx-2 homeobox genes in the intestine Biochem Cell Biol 76 957 969 10.1139/bcb-76-6-957 10392709 1:CAS:528:DyaK1MXjvF2rsL4%3D (Pubitemid 29450564)
13. E Suh PG Traber 1996 An intestine-specific homeobox gene regulates proliferation and differentiation Mol Cell Biol 16 619 625 8552090 1:CAS:528:DyaK28XmtVWhtw%3D%3D
14. A Eda H Osawa I Yanaka K Satoh H Mutoh K Kihira K Sugano 2002 Expression of homeobox gene CDX2 precedes that of CDX1 during the progression of intestinal metaplasia J Gastroenterol 37 94 100 10.1007/s005350200002 11871772 1:CAS:528:DC%2BD38XitVWrt7w%3D (Pubitemid 34223741)
15. A Eda H Osawa K Satoh I Yanaka K Kihira Y Ishino H Mutoh K Sugano 2003 Aberrant expression of CDX2 in Barrett'sepithelium and inflammatory esophageal mucosa J Gastroenterol 38 14 22 10.1007/s005350300001 12560917 1:CAS:528:DC%2BD3sXovFajtw%3D%3D (Pubitemid 36267690)
16. S Ko KM Chu JM Luk BW Wong ST Yuen SY Leung J Wong 2005 CDX2 co-localizes with liver-intestine cadherin in intestinal metaplasia and adenocarcinoma of the stomach J Pathol 205 615 622 10.1002/path.1741 15732140 1:CAS:528: DC%2BD2MXjvVajtbg%3D (Pubitemid 40514835)
17. B Ranscht 1994 Cadherins and catenins: interactions and functions in embryogenic development Curr Opin Cell Biol 6 740 746 10.1016/0955-0674(94) 90102-3 7833053 1:CAS:528:DyaK2cXmt1Kqurs%3D
18. M Takeichi 1995 Morphogenetic roles of classic cadherins Curr Opin Cell Biol 7 619 627 10.1016/0955-0674(95)80102-2 8573335 1:CAS:528:DyaK2MXosVKnsr8%3D
19. M Takeichei 1993 Cadherins in cancer: implications for invasion and metastasis Curr Opin Cell Biol 5 806 811 10.1016/0955-0674(93)90029-P
20. S Hirohashi 1998 Inactivation of the E-cadherin-mediated cell adhesion system in human cancers Am J Pathol 153 333 339 9708792 1:CAS:528: DyaK1cXls1ejsbw%3D
21. 2+-dependent cell adhesion molecule expressed in liver and intestine J Cell Biol 125 1353 1369 10.1083/jcb.125.6. 1353 8207063 1:CAS:528:DyaK2cXjtFyjsrc%3D (Pubitemid 24189538)
22. R Gessner R Tauber 2000 Intestinal cell adhesion molecules. Liver-intestine cadherin Ann NY Acad Sci 915 136 143 10.1111/j.1749-6632.2000. tb05236.x 11193569 1:CAS:528:DC%2BD3MXntVCgtA%3D%3D
23. T Hinoi PC Lucas R Kuick S Hanash KR Cho ER Fearon 2002 CDX2 regulates liver intestine-cadherin expression in normal and malignant colon epithelium and intestinal metaplasia Gastroenterology 123 1565 1577 10.1053/gast.2002.36598 12404231 1:CAS:528:DC%2BD38XptVGjsbw%3D
24. C Grötzinger J Kneifel D Patschan N Schnoy I Anagnostopoulos S Faiss R Tauber B Wiedenmann R Gessner 2001 LI-cadherin: a marker of gastric metaplasia and neoplasia Gut 49 8 10.1136/gut.49.1.73 (Pubitemid 32601882)
25. BW Wong JM Luk IO Ng MY Hu KD Liu ST Fan 2003 Identification of liver-intestine cadherin in hepatocellular carcinoma-a potential disease marker Biochem Biophys Res Commun 311 618 624 10.1016/j.bbrc.2003.10.032 14623315 1:CAS:528:DC%2BD3sXos12ltLs%3D (Pubitemid 37377699)
26. M Takamura M Sakamoto Y Ino T Shimamura T Ichida H Asakura S Hirohashi 2003 Expression of liver-intestine cadherin and its possible interaction with galectin-3 in ductal adenocarcinoma of the pancreas Cancer Sci 94 425 430 10.1111/j.1349-7006.2003.tb01459.x 12824888 1:CAS:528:DC%2BD3sXls1WrtLw%3D
27. RC Fitzgerald MB Omary G Triadafilopoulos 1997 Acid modulation of HT29 cell growth and differentiation: an in vitro model for Barrett's esophagus J Cell Sci 110 663 671 9092948 1:CAS:528:DyaK2sXitlamsrY%3D
28. T Niwa Y Ikehara H Nakanishi, et al. 2005 Mixed gastric- and intestinal-type metaplasia is formed by cells with dual intestinal and gastric differentiation J Histochem Cytochem 53 75 85 10.1369/jhc.4A6443.2005 15637340 1:CAS:528:DC%2BD2MXot12gtw%3D%3D (Pubitemid 40130122)
29. B Dudouet S Robine C Huet, et al. 1987 Changes in villin synthesis and subcellular distribution during intestinal differentiation of HT29-18 clones J Cell Biol 105 359 369 10.1083/jcb.105.1.359 2440895 1:CAS:528:DyaL2sXkvFChtbg%3D (Pubitemid 17101255)
30. M Furuse H Sasaki S Tsukita 1999 Manner of interaction of heterogeneous claudin species within and between tight junction strands J Cell Biol 147 891 903 10.1083/jcb.147.4.891 10562289 1:CAS:528:DyaK1MXnsFSqtbo%3D
31. N Sawada M Murata K Kikuchi M Osanai H Tobioka T Kojima H Chiba 2003 Tight junctions and human diseases Med Electron Microsc 36 147 156 10.1007/s00795-003-0219-y 14505058 (Pubitemid 37288275)
32. S Offner A Hekele U Teichmann S Weinberger S Gross P Kufer C Itin PA Baeuerle B Kohleisen 2004 Epithelial tight junction proteins as potential antibody targets for pancarcinoma therapy Cancer Immunol Immunother 54 431 445 10.1007/s00262-004-0613-x 15750830 1:CAS:528:DC%2BD2MXhvFyrsLo%3D
33. P Michl M Buchholz M Rolke S Kunsch M Lohr B McClane S Tsukita G Leder G Adler TM Gress 2001 Claudin-4: a new target for pancreatic cancer treatment using Clostridium perfringens enterotoxin Gastroenterology 121 678 684 10.1053/gast.2001.27124 11522752 1:CAS:528:DC%2BD3MXntVKnsbc%3D
34. SB Ho GH Niehans C Lyftogt PS Yan DL Cherwitz, et al. 1993 Heterogeneity of mucin gene expression in normal and neoplastic tissues Cancer Res 53 641 651 7678777 1:CAS:528:DyaK3sXhsVClu7g%3D
35. SC Burjonrappa S Reedimasu Z Nawaz, et al. 2009 Mucin expression profile in Barrett́s, dysplasia, adenocarcinoma sequence in the esophagus Indian J Cancer 44 1 5 10.4103/0019-509X.31160
36. M Blaszczyk-Thurin M Ramachandran MAJ Westerink, et al. 1996 Molecular recognition of the Lewis Y antigen by monoclonal antibodies Prot Engineering 5 447 459 10.1093/protein/9.5.447
37. Werner M, Flejou JF, Hainaut P, Hoefler H, Lambert R, Keller G, Stein HJ (2000) Adenocarcinoma of the oesophagus. In: Hamilton SR, Aaltonen LA (eds) WHO classification of tumours, pathology & genetics, tumors of the digestive system. IARC Press, Lyon, pp 20-26
38. A Weimann M Zimmermann M Gross H Slevogt A Rieger L Morawietz 2010 CDX2 and LI-cadherin expression in esophageal mucosa: use of both markers can facilitate the histologic diagnosis of Barrett's esophagus and carcinoma Int J Surg Pathol 10.1177/1066896910364428 20444732
39. W Remmele HE Stegner 1987 Recommendation for uniform definition of an immunoreactive score (IRS) for immunohistochemical estrogen receptor detection (ER-ICA) in breast cancer tissue Pathologe 8 138 140 3303008 1:STN:280:DyaL2s3ovFGhsQ%3D%3D
40. M Conio G Lapertosa S Blanchi R Filiberti 2003 Barrett's esophagus: an update Crit Rev Oncol Hematol 46 187 206 10.1016/S1040-8428(02)00123-3 12711361 (Pubitemid 36444633)
41. GW Falk 2002 Barrett's esophagus Gastroenterology 122 1569 1591 10.1053/gast.2002.33427 12016424
42. MB Menke-Pluymers AH Mulder WC Hop M van Blankenstein HW Tilanus 1994 Dysplasia and aneuploidy as markers of malignant degeneration in Barrett's oesophagus. The Rotterdam Oesophageal Tumour Study Group Gut 35 1348 1351 10.1136/gut.35.10.1348 7959183 1:STN:280:DyaK2M%2FkslKksw%3D%3D
43. BJ Reid DS Levine G Longton PL Blount PS Rabinovitch 2000 Predictors of progression to cancer in Barrett's esophagus: baseline histology and flow cytometry identify low- and high-risk patient subsets Am J Gastroenterol 95 1669 1676 10925966 1:STN:280:DC%2BD3cvgvVWntQ%3D%3D
44. S Ko KM Chu JM Luk BW Wong ST Yuen SY Leung J Wong 2004 Overexpression of LI-cadherin in gastric cancer is associated with lymph node metastasis Biochem Biophys Res Commun 319 562 568 10.1016/j.bbrc.2004.04.197 15178443 1:CAS:528:DC%2BD2cXkslSjuro%3D (Pubitemid 38725983)
45. RW Phillips HF Frierson Jr CA Moskaluk 2003 Cdx2 as a marker of epithelial intestinal differentiation in the esophagus Am J Surg Pathol 27 1442 1447 10.1097/00000478-200311000-00006 14576477 (Pubitemid 37315196)
46. M Noguchi T Nakajima S Hirohashi T Akiba Y Shimosato 1989 Immunohistochemical distinction of malignant mesothelioma from pulmonary adenocarcinoma with anti-surfactant apoprotein, anti-Lewisa, and anti-Tn antibodies Hum Pathol 20 53 57 10.1016/0046-8177(89)90202-5 2912874 1:STN:280:DyaL1M7gvVCitg%3D%3D (Pubitemid 19041995)
47. JR Riera C Astengo-Osuna JA Longmate H Battifora 1997 The immunohistochemical diagnostic panel for epithelial mesothelioma. A reevaluation after heat-induced epitope retrieval Am J Surg Pathol 21 1409 1419 10.1097/00000478-199712000-00003 9414184 1:STN:280:DyaK1c%2FnsV2qtw%3D%3D (Pubitemid 27528251)
48. WK Kauer JH Peters TR DeMeester AP Ireland CG Bremner JA Hagen 1995 Mixed reflux of gastric and duodenal juices is more harmful to the esophagus than gastric juice alone: the need for surgical therapy re-emphasized Ann Surg 222 525 531 7574932 1:STN:280:DyaK28%2FisFWhsQ%3D%3D
49. H Yamamoto YQ Bai Y Yuasa 2003 Homeodomain protein CDX2 regulates goblet-specific MUC2 gene expression Biochem Biophys Res Commun 300 813 818 10.1016/S0006-291X(02)02935-2 12559945 1:CAS:528:DC%2BD3sXmsVCgsg%3D%3D (Pubitemid 36259834)
50. N Yamamichi KI Inada C Furukawa K Sakurai, et al. 2009 Cdx2 and the Brm-type SWI/SNF complex cooperatively regulate villin expression in gastrointestinal cells Exp Cell Res 315 1779 1789 10.1016/j.yexcr.2009.01.006 19371634 1:CAS:528:DC%2BD1MXlslWitL0%3D
51. B Jovov CM Van Itallie NJ Shaheen JL Carson, et al. 2007 Claudin-18: a dominant tight junction protein in Barrett's esophagus and likely contributor to its acid resistance Am J Physiol Gastrointest Liver Physiol 293 1106 1113 10.1152/ajpgi.00158.2007 1:CAS:528:DC%2BD2sXhsVGls7bO (Pubitemid 350255034)
52. H Györffy A Holczbauer P Nagy Z Szabó, et al. 2005 Claudin expression in Barrett's esophagus and adenocarcinoma Virchows Arch 447 961 968 10.1007/s00428-005-0045-9 16133365 1:CAS:528:DC%2BD2MXht1Gnu7vI (Pubitemid 41719551)