High-resolution crystal structures of villin headpiece and mutants with reduced F-actin binding activity

Biochemistry

Volumn 44, Issue 36, 2005, Pages 11963-11973

  Meng, Jianmin ^a   Vardar, Didem ^a,b   Wang, Yeming ^a   Guo, Hwai Chen ^a   Head, James F ^a   McKnight, C James ^a  

^a BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; CYTOLOGY; PROTEINS; STABILITY;

BINDING AFFINITY; HIGH-RESOLUTION CRYSTAL STRUCTURES; MUTANTS; VILLIN HEADPIECE;

CRYSTAL STRUCTURE;

ACTIN; ACTIN BINDING PROTEIN; ALANINE; AMINO ACID; ARGININE; F ACTIN; MUTANT PROTEIN; TRYPTOPHAN; TYROSINE; UNCLASSIFIED DRUG; VILLIN; VILLIN HEADPIECE;

AMINO ACID SEQUENCE; ARTICLE; BINDING AFFINITY; BINDING SITE; BRUSH BORDER; CARBOXY TERMINAL SEQUENCE; CHICKEN; CRYSTAL STRUCTURE; INTESTINE EPITHELIUM; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN FOLDING; PROTEIN MOTIF; SEDIMENTATION; STRUCTURE ANALYSIS;

ACTINS; ANIMALS; AVIAN PROTEINS; CHICKENS; CIRCULAR DICHROISM; CRYSTALLOGRAPHY, X-RAY; MICROFILAMENT PROTEINS; MODELS, MOLECULAR; MUTATION; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PROTEIN BINDING; PROTEIN DENATURATION; PROTEIN STRUCTURE, TERTIARY; TEMPERATURE;

EID: 24644519821     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi050850x     Document Type: Article

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