Incretin response to a standard test meal in a rat model of sleeve gastrectomy with diet-induced obesity

Obesity Surgery

Volumn 24, Issue 1, 2014, Pages 95-101

  Al Sabah, Suleiman ^a   Alasfar, Fahad ^a   Al Khaledi, Ghanim ^a   Dinesh, Reshma ^a   Al Saleh, Mervat ^a   Abul, Habib ^a  

^a KUWAIT UNIVERSITY   (Kuwait)

Author keywords

Diet induced obesity; GIP; GLP 1; Incretin; Rats; Sleeve gastrectomy

Indexed keywords

GASTRIC INHIBITORY POLYPEPTIDE; GLUCAGON LIKE PEPTIDE 1; GLUCOSE; INCRETIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; DIET RESTRICTION; GLUCOSE BLOOD LEVEL; HORMONE BLOOD LEVEL; JUGULAR VEIN; LIPID DIET; MALE; NONHUMAN; OBESITY; ORAL GLUCOSE TOLERANCE TEST; PRIORITY JOURNAL; RAT; SLEEVE GASTRECTOMY; SUGAR INTAKE; TEST MEAL; VASCULAR ACCESS; WEIGHT CHANGE;

ANIMALS; BLOOD GLUCOSE; DIET; DISEASE MODELS, ANIMAL; GASTRECTOMY; GLUCAGON-LIKE PEPTIDE 1; INCRETINS; MALE; OBESITY; RATS; RATS, SPRAGUE-DAWLEY;

EID: 84893665993     PISSN: 09608923     EISSN: 17080428     Source Type: Journal    
DOI: 10.1007/s11695-013-1056-2     Document Type: Article

References (28)

1. Peterli R, Wölnerhanssen B, Peters T, et al. Improvement in glucose metabolism after bariatric surgery: comparison of laparoscopic Roux-en-Y gastric bypass and laparoscopic sleeve gastrectomy: a prospective randomized trial. Ann Surg. 2009;250(2):234-41. PMID: 19638921.
2. Romero F, Nicolau J, Flores L, et al. Comparable early changes in gastrointestinal hormones after sleeve gastrectomy and Roux-en-Y gastric bypass surgery for morbidly obese type 2 diabetic subjects. Surg Endosc. 2012;26(8):2231-9. PMID: 22302537.
3. Kim W, Egan JM. The role of incretins in glucose homeostasis and diabetes treatment. Pharmacol Rev. 2008;60(4):470-512. PMCID: PMC2696340.
4. Nauck MA, Heimesaat MM, Orskov C, et al. Preserved incretin activity of glucagon-like peptide 1 [7-36 amide] but not of synthetic human gastric inhibitory polypeptide in patients with type-2 diabetes mellitus. J Clin Invest. 1993;91(1):301-7. PubMed PMID: 8423228; PubMed Central PMCID: PMC330027.
5. Donnelly D. The structure and function of the glucagon-like peptide-1 receptor and its ligands. Br J Pharmacol. 2012;166(1):27-41. doi: 10.1111/j.1476-5381.2011.01687.x. Review. PubMed PMID: 21950636; PubMed Central PMCID: PMC3415635.
6. Laferrère B, Heshka S, Wang K, et al. Incretin levels and effect are markedly enhanced 1 month after Roux-en-Y gastric bypass surgery in obese patients with type 2 diabetes. Diabetes Care. 2007;30(7):1709-16. PubMed PMID: 17416796; PubMed Central PMCID: PMC2743330.
7. Korner J, Bessler M, Inabnet W, et al. Exaggerated glucagon-like peptide-1 and blunted glucose-dependent insulinotropic peptide secretion are associated with Roux-en-Y gastric bypass but not adjustable gastric banding. Surg Obes Relat Dis. 2007;3(6):597-601. Epub 2007 Oct 23. PubMed PMID: 17936091; PubMed Central PMCID: PMC2134840.
8. Kashyap SR, Daud S, Kelly KR, et al. Acute effects of gastric bypass versus gastric restrictive surgery on beta-cell function and insulinotropic hormones in severely obese patients with type 2 diabetes. Int J Obes (Lond). 2010;34(3):462-71. doi: 10.1038/ijo.2009.254. Epub 2009 Dec 22. PubMed PMID: 20029383; PubMed Central PMCID: PMC2838991.
9. Romero F, Nicolau J, Flores L, et al. Comparable early changes in gastrointestinal hormones after sleeve gastrectomy and Roux-en-Y gastric bypass surgery for morbidly obese type 2 diabetic subjects. Surg Endosc. 2012;26(8):2231-9. doi: 10.1007/s00464-012-2166-y. PubMed PMID: 22302537.
10. Tseng CC, Boylan MO, Jarboe LA, et al. Chronic desensitization of the glucose-dependent insulinotropic polypeptide receptor in diabetic rats. Am J Physiol. 1996;270(4 Pt 1):E661-6. PubMed PMID: 8928774.
11. Martire SI, Holmes N, Westbrook RF, et al. Altered feeding patterns in rats exposed to a palatable cafeteria diet: increased snacking and its implications for development of obesity. PLoS One. 2013;8(4):e60407. doi: 10.1371/journal.pone.0060407. Epub 2013 Apr 2. PMID: 23565243 [PubMed-in process] PMCID: PMC3614998.
12. Thrivikraman KV, Huot RL, Plotsky PM. Jugular vein catheterization for repeated blood sampling in the unrestrained conscious rat. Brain Res Brain Res Protoc. 2002;10(2):84-94. PubMed PMID: 12431707.
13. Diehl KH, Hull R, Morton D, European Federation of Pharmaceutical Industries Association and European Centre for the Validation of Alternative Methods, et al. A good practice guide to the administration of substances and removal of blood, including routes and volumes. J Appl Toxicol. 2001;21(1):15-23. PubMed PMID: 11180276.
14. Gunnarsson PT, Winzell MS, Deacon CF, et al. Glucose-induced incretin hormone release and inactivation are differently modulated by oral fat and protein in mice. Endocrinology. 2006;147(7):3173-80. Epub 2006 Apr 20. PubMed PMID: 16627575.
15. Carr RD, Larsen MO, Winzell MS, et al. Incretin and islet hormonal responses to fat and protein ingestion in healthy men. Am J Physiol Endocrinol Metab. 2008;295(4):E779-84. doi: 10.1152/ajpendo.90233.2008. Epub 2008 Jul 8. PubMed PMID: 18612044.
16. Horowitz M, Cook DJ, Collins PJ, et al. Measurement of gastric emptying after gastric bypass surgery using radionuclides. Br J Surg. 1982;69(11):655-7. PubMed PMID: 7127049.
17. Melissas J, Koukouraki S, Askoxylakis J, et al. Sleeve gastrectomy: a restrictive procedure? Obes Surg. 2007;17(1):57-62. PubMed PMID: 17355769.
18. Diep TA, Madsen AN, Holst B, et al. Dietary fat decreases intestinal levels of the anorectic lipids through a fat sensor. FASEB J. 2011;25(2):765-74. doi: 10.1096/fj.10-166595. Epub 2010 Oct 19. PubMed PMID: 2095916.
19. Valderas JP, Irribarra V, Rubio L, et al. Effects of sleeve gastrectomy and medical treatment for obesity on glucagon-like peptide 1 levels and glucose homeostasis in non-diabetic subjects. Obes Surg. 2011;21(7):902-9. doi: 10.1007/s11695-011-0375-4. PubMed PMID: 21347823.
20. Chambers AP, Stefater MA, Wilson-Perez HE, et al. Similar effects of Roux-en-Y gastric bypass and vertical sleeve gastrectomy on glucose regulation in rats. Physiol Behav. 2011;105(1):120-3. doi: 10.1016/j.physbeh.2011.05.026. Epub 2011 Jun 12. PubMed PMID: 21683726.
21. Holst JJ, Schwartz TW, Lovgreen NA, et al. Diurnal profile of pancreatic polypeptide, pancreatic glucagon, gut glucagon and insulin in human morbid obesity. Int J Obes. 1983;7(6):529-38. PubMed PMID: 6360922.
22. Näslund E, Grybäck P, Backman L, et al. Distal small bowel hormones: correlation with fasting antroduodenal motility and gastric emptying. Dig Dis Sci. 1998;43(5):945-52. PubMed PMID: 9590405.
23. Basso N, Capoccia D, Rizzello M, et al. First-phase insulin secretion, insulin sensitivity, ghrelin, GLP-1, and PYY changes 72 h after sleeve gastrectomy in obese diabetic patients: the gastric hypothesis. Surg Endosc. 2011;25(11):3540-50. doi: 10.1007/s00464-011-1755-5. Epub 2011 Jun 3. PubMed PMID: 21638183.
24. Papamargaritis D, Koukoulis G, Sioka E, et al. Dumping symptoms and incidence of hypoglycaemia after provocation test at 6 and 12 months after laparoscopic sleeve gastrectomy. Obes Surg. 2012;22(10):1600-6. doi: 10.1007/s11695-012-0711-3. PubMed PMID: 22773085.
25. Tack J, Arts J, Caenepeel P, et al. Pathophysiology, diagnosis and management of postoperative dumping syndrome. Nat Rev Gastroenterol Hepatol. 2009;6(10):583-90. doi: 10.1038/nrgastro.2009.148. Epub 2009 Sep 1. Review. PubMed PMID: 19724252.
26. Vilsbøll T, Krarup T, Madsbad S, et al. Defective amplification of the late phase insulin response to glucose by GIP in obese type II diabetic patients. Diabetologia. 2002;45(8):1111-9. Epub 2002 Jul 4. PubMed PMID: 12189441.
27. Zhou J, Livak MF, Bernier M, et al. Ubiquitination is involved in glucose-mediated downregulation of GIP receptors in islets. Am J Physiol Endocrinol Metab. 2007;293(2):E538-47. Epub 2007 May 15. PubMed PMID: 17505054; PubMed Central PMCID: PMC2640485.
28. Cummings BP, Bremer AA, Kieffer TJ, et al. Investigation of the mechanisms contributing to the compensatory increase in insulin secretion during dexamethasone-induced insulin resistance in rhesus macaques. J Endocrinol. 2013;216(2):207-15. doi: 10.1530/JOE-12-0459. Print 2013. PMID: 23151361.