메뉴 건너뛰기




Volumn 33, Issue 6, 2014, Pages 794-803

ISGylation governs the oncogenic function of Ki-Ras in breast cancer

Author keywords

breast cancer; ISG15; ISGylation; Ki Ras; oncogenic transformation; UbcH8

Indexed keywords

SHORT HAIRPIN RNA;

EID: 84893644001     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2012.633     Document Type: Article
Times cited : (68)

References (53)
  • 2
    • 33751257187 scopus 로고    scopus 로고
    • The interferon regulated ubiquitin-like protein, ISG15, in tumorigenesis: Friend or foe?
    • Andersen JB, Hassel BA. The interferon regulated ubiquitin-like protein, ISG15, in tumorigenesis: friend or foe? Cytokine Growth Factor Rev 2006; 17: 411-421.
    • (2006) Cytokine Growth Factor Rev , vol.17 , pp. 411-421
    • Andersen, J.B.1    Hassel, B.A.2
  • 3
    • 65849226334 scopus 로고    scopus 로고
    • The ubiquitinlike molecule interferon-stimulated gene 15 (ISG15) is a potential prognostic marker in human breast cancer
    • Bektas N, Noetzel E, Veeck J, Press MF, Kristiansen G, Naami A et al. The ubiquitinlike molecule interferon-stimulated gene 15 (ISG15) is a potential prognostic marker in human breast cancer. Breast Cancer Res 2008; 10: R58.
    • (2008) Breast Cancer Res , vol.10
    • Bektas, N.1    Noetzel, E.2    Veeck, J.3    Press, M.F.4    Kristiansen, G.5    Naami, A.6
  • 4
    • 31544460359 scopus 로고    scopus 로고
    • Elevated expression of ISG15 in tumor cells interferes with the ubiquitin/26S proteasome pathway
    • Desai SD, Haas AL, Wood LM, Tsai YC, Pestka S, Rubin EH et al. Elevated expression of ISG15 in tumor cells interferes with the ubiquitin/26S proteasome pathway. Cancer Res 2006; 66: 921-928.
    • (2006) Cancer Res , vol.66 , pp. 921-928
    • Desai, S.D.1    Haas, A.L.2    Wood, L.M.3    Tsai, Y.C.4    Pestka, S.5    Rubin, E.H.6
  • 5
    • 0023160888 scopus 로고
    • Interferon induces a 15-kilodalton protein exhibitingmarked homology to ubiquitin
    • Haas AL, Ahrens P, Bright PM, Ankel H. Interferon induces a 15-kilodalton protein exhibitingmarked homology to ubiquitin. J Biol Chem 1987; 262: 11315-11323.
    • (1987) J Biol Chem , vol.262 , pp. 11315-11323
    • Haas, A.L.1    Ahrens, P.2    Bright, P.M.3    Ankel, H.4
  • 6
    • 67651122930 scopus 로고    scopus 로고
    • Expression, regulation and function of the ISGylation system in prostate cancer
    • Kiessling A, Hogrefe C, Erb S, Bobach C, Fuessel S, Wessjohann L et al. Expression, regulation and function of the ISGylation system in prostate cancer. Oncogene 2009; 28: 2606-2620.
    • (2009) Oncogene , vol.28 , pp. 2606-2620
    • Kiessling, A.1    Hogrefe, C.2    Erb, S.3    Bobach, C.4    Fuessel, S.5    Wessjohann, L.6
  • 7
    • 0026526147 scopus 로고
    • Induced expression of the endogenous beta interferon gene in adenovirus type 5-transformed rat fibroblasts
    • Nielsch U, Pine R, Zimmer SG, Babiss LE. Induced expression of the endogenous beta interferon gene in adenovirus type 5-transformed rat fibroblasts. J Virol 1992; 66: 1884-1890.
    • (1992) J Virol , vol.66 , pp. 1884-1890
    • Nielsch, U.1    Pine, R.2    Zimmer, S.G.3    Babiss, L.E.4
  • 9
    • 0034904982 scopus 로고    scopus 로고
    • Role for p53 in gene induction by double-stranded RNA
    • Hummer BT, Li XL, Hassel BA. Role for p53 in gene induction by double-stranded RNA. J Virol 2001; 75: 7774-7777.
    • (2001) J Virol , vol.75 , pp. 7774-7777
    • Hummer, B.T.1    Li, X.L.2    Hassel, B.A.3
  • 10
    • 79551510429 scopus 로고    scopus 로고
    • A novel role for ATM in regulating proteasome-mediated protein degradation through suppression of the ISG15 conjugation pathway
    • Wood LM, Sankar S, Reed RE, Haas AL, Liu LF, McKinnon P et al. A novel role for ATM in regulating proteasome-mediated protein degradation through suppression of the ISG15 conjugation pathway. PLoS ONE 2011; 6: e16422.
    • (2011) PLoS ONE , vol.6
    • Wood, L.M.1    Sankar, S.2    Reed, R.E.3    Haas, A.L.4    Liu, L.F.5    McKinnon, P.6
  • 11
    • 12844275047 scopus 로고    scopus 로고
    • Down-regulation of UCRP and UBE2L6 in BRCA2 knocked-down human breast cells
    • Tripathi MK, Chaudhuri G. Down-regulation of UCRP and UBE2L6 in BRCA2 knocked-down human breast cells. Biochem Biophys Res Commun 2005; 328: 43-48.
    • (2005) Biochem Biophys Res Commun , vol.328 , pp. 43-48
    • Tripathi, M.K.1    Chaudhuri, G.2
  • 12
    • 77951481221 scopus 로고    scopus 로고
    • Antiviral activity of innate immune protein ISG15
    • Harty RN, Pitha PM, Okumura A. Antiviral activity of innate immune protein ISG15. J Innate Immun 2009; 1: 397-404.
    • (2009) J Innate Immun , vol.1 , pp. 397-404
    • Harty, R.N.1    Pitha, P.M.2    Okumura, A.3
  • 15
    • 7444232643 scopus 로고    scopus 로고
    • Microarray analyses uncover UBE1L as a candidate target gene for lung cancer chemoprevention
    • Pitha-Rowe I, Petty WJ, Feng Q, Koza-Taylor PH, Dimattia DA, Pinder L et al. Microarray analyses uncover UBE1L as a candidate target gene for lung cancer chemoprevention. Cancer Res 2004; 64: 8109-8115.
    • (2004) Cancer Res , vol.64 , pp. 8109-8115
    • Pitha-Rowe, I.1    Petty, W.J.2    Feng, Q.3    Koza-Taylor, P.H.4    Dimattia, D.A.5    Pinder, L.6
  • 17
    • 1642312315 scopus 로고    scopus 로고
    • Genetic alterations in pancreatic carcinoma
    • Schneider G, Schmid RM. Genetic alterations in pancreatic carcinoma. Mol Cancer 2003; 2: 15.
    • (2003) Mol Cancer , vol.2 , pp. 15
    • Schneider, G.1    Schmid, R.M.2
  • 18
    • 16844376315 scopus 로고    scopus 로고
    • Oncogenic Ras in tumour progression and metastasis
    • Giehl K. Oncogenic Ras in tumour progression and metastasis. Biol Chem 2005; 386: 193-205.
    • (2005) Biol Chem , vol.386 , pp. 193-205
    • Giehl, K.1
  • 19
    • 0027905014 scopus 로고
    • Altered growth of human colon cancer cell lines disrupted at activated Ki-ras
    • Shirasawa S, Furuse M, Yokoyama N, Sasazuki T. Altered growth of human colon cancer cell lines disrupted at activated Ki-ras. Science 1993; 260: 85-88.
    • (1993) Science , vol.260 , pp. 85-88
    • Shirasawa, S.1    Furuse, M.2    Yokoyama, N.3    Sasazuki, T.4
  • 20
    • 0021265128 scopus 로고
    • Actin cytoskeletal organization loss in the benign-to-malignant tumor transition in cultured human colonic epithelial cells
    • Friedman E, Verderame M, Winawer S, Pollack R. Actin cytoskeletal organization loss in the benign-to-malignant tumor transition in cultured human colonic epithelial cells. Cancer Res 1984; 44: 3040-3050.
    • (1984) Cancer Res , vol.44 , pp. 3040-3050
    • Friedman, E.1    Verderame, M.2    Winawer, S.3    Pollack, R.4
  • 21
    • 33947230755 scopus 로고    scopus 로고
    • Phosphatidylinositol-3-OH kinase or RAS pathway mutations in human breast cancer cell lines
    • Hollestelle A, Elstrodt F, Nagel JH, Kallemeijn WW, Schutte M. Phosphatidylinositol-3-OH kinase or RAS pathway mutations in human breast cancer cell lines. Mol Cancer Res 2007; 5: 195-201.
    • (2007) Mol Cancer Res , vol.5 , pp. 195-201
    • Hollestelle, A.1    Elstrodt, F.2    Nagel, J.H.3    Kallemeijn, W.W.4    Schutte, M.5
  • 22
    • 3042742432 scopus 로고    scopus 로고
    • Involvement of Ras activation in human breast cancer cell signaling, invasion, and anoikis
    • Eckert LB, Repasky GA, Ulkü AS, McFall A, Zhou H, Sartor CI et al. Involvement of Ras activation in human breast cancer cell signaling, invasion, and anoikis. Cancer Res 2004; 64: 4585-4592.
    • (2004) Cancer Res , vol.64 , pp. 4585-4592
    • Eckert, L.B.1    Repasky, G.A.2    Ulkü, A.S.3    McFall, A.4    Zhou, H.5    Sartor, C.I.6
  • 23
    • 34548710863 scopus 로고    scopus 로고
    • Knock-in of mutant K-ras in nontumorigenic human epithelial cells as a new model for studying K-ras mediated transformation
    • Konishi H, Karakas B, Abukhdeir AM, Lauring J, Gustin JP, Garay JP et al. Knock-in of mutant K-ras in nontumorigenic human epithelial cells as a new model for studying K-ras mediated transformation. Cancer Res 2007; 67: 8460-8467.
    • (2007) Cancer Res , vol.67 , pp. 8460-8467
    • Konishi, H.1    Karakas, B.2    Abukhdeir, A.M.3    Lauring, J.4    Gustin, J.P.5    Garay, J.P.6
  • 24
    • 66949151103 scopus 로고    scopus 로고
    • H-Ras is degraded by Wnt/beta-catenin signaling via beta-TrCP-mediated polyubiquitylation
    • Kim SE, Yoon JY, Jeong WJ, Jeon SH, Park Y, Yoon JB et al. H-Ras is degraded by Wnt/beta-catenin signaling via beta-TrCP-mediated polyubiquitylation. J Cell Sci 2009; 122: 842-848.
    • (2009) J Cell Sci , vol.122 , pp. 842-848
    • Kim, S.E.1    Yoon, J.Y.2    Jeong, W.J.3    Jeon, S.H.4    Park, Y.5    Yoon, J.B.6
  • 25
    • 0034967925 scopus 로고    scopus 로고
    • The ubiquitin-proteasome pathway and proteasome inhibitors
    • Myung J, Kim KB, Crews CM. The ubiquitin-proteasome pathway and proteasome inhibitors. Med Res Rev 2001; 21: 245-273.
    • (2001) Med Res Rev , vol.21 , pp. 245-273
    • Myung, J.1    Kim, K.B.2    Crews, C.M.3
  • 26
    • 0028935165 scopus 로고
    • Ubiquitin, proteasomes, and the regulation of intracellular protein degradation
    • Hochstrasser M. Ubiquitin, proteasomes, and the regulation of intracellular protein degradation. Curr Opin Cell Biol 1995; 7: 215-223.
    • (1995) Curr Opin Cell Biol , vol.7 , pp. 215-223
    • Hochstrasser, M.1
  • 27
    • 23944474123 scopus 로고    scopus 로고
    • Early work on the ubiquitin proteasome system, an interview with Aaron Ciechanover
    • Ciechanover A. Early work on the ubiquitin proteasome system, an interview with Aaron Ciechanover. Interview by CDD. Cell Death Differ 2005; 12: 1167-1177.
    • (2005) Interview by CDD. Cell Death Differ , vol.12 , pp. 1167-1177
    • Ciechanover, A.1
  • 28
    • 33846471122 scopus 로고    scopus 로고
    • Proteasome-independent functions of ubiquitin in endocytosis and signaling
    • Mukhopadhyay D, Riezman H. Proteasome-independent functions of ubiquitin in endocytosis and signaling. Science 2007; 315: 201-205.
    • (2007) Science , vol.315 , pp. 201-205
    • Mukhopadhyay, D.1    Riezman, H.2
  • 29
    • 65649128660 scopus 로고    scopus 로고
    • K63-linked ubiquitin chains as a specific signal for protein sorting into the multivesicular body pathway
    • Lauwers E, Jacob C, Andre B. K63-linked ubiquitin chains as a specific signal for protein sorting into the multivesicular body pathway. J Cell Biol 2009; 185: 493-502.
    • (2009) J Cell Biol , vol.185 , pp. 493-502
    • Lauwers, E.1    Jacob, C.2    Andre, B.3
  • 30
    • 0030772933 scopus 로고    scopus 로고
    • Targeting of substrates to the 26S proteasome
    • Pickart CM. Targeting of substrates to the 26S proteasome. FASEB J 1997; 11: 1055-1066.
    • (1997) FASEB J , vol.11 , pp. 1055-1066
    • Pickart, C.M.1
  • 31
    • 0034327504 scopus 로고    scopus 로고
    • Ubiquitin in chains
    • Pickart CM. Ubiquitin in chains. Trends Biochem Sci 2000; 25: 544-548.
    • (2000) Trends Biochem Sci , vol.25 , pp. 544-548
    • Pickart, C.M.1
  • 32
    • 24344477111 scopus 로고    scopus 로고
    • ISG15 modification of Ubc13 suppresses its ubiquitin-conjugating activity
    • Takeuchi T, Yokosawa H. ISG15 modification of Ubc13 suppresses its ubiquitin-conjugating activity. Biochem Biophys Res Commun 2005; 336: 9-13.
    • (2005) Biochem Biophys Res Commun , vol.336 , pp. 9-13
    • Takeuchi, T.1    Yokosawa, H.2
  • 33
    • 24344449085 scopus 로고    scopus 로고
    • ISG15 modification of ubiquitin E2 Ubc13 disrupts its ability to form thioester bond with ubiquitin
    • Zou W, Papov V, Malakhova O, Kim KI, Dao C, Li J et al. ISG15 modification of ubiquitin E2 Ubc13 disrupts its ability to form thioester bond with ubiquitin. Biochem Biophys Res Commun 2005; 336: 61-68.
    • (2005) Biochem Biophys Res Commun , vol.336 , pp. 61-68
    • Zou, W.1    Papov, V.2    Malakhova, O.3    Kim, K.I.4    Dao, C.5    Li, J.6
  • 34
    • 33846317359 scopus 로고    scopus 로고
    • Negative regulation of ISG15 E3 ligase EFP through its autoISGylation
    • Zou W, Wang J, Zhang DE. Negative regulation of ISG15 E3 ligase EFP through its autoISGylation. Biochem Biophys Res Commun 2007; 354: 321-327.
    • (2007) Biochem Biophys Res Commun , vol.354 , pp. 321-327
    • Zou, W.1    Wang, J.2    Zhang, D.E.3
  • 35
    • 32944461462 scopus 로고    scopus 로고
    • Link between the ubiquitin conjugation system and the ISG15 conjugation system: ISG15 conjugation to the UbcH6 ubiquitin E2 enzyme
    • Takeuchi T, Iwahara S, Saeki Y, Sasajima H, Yokosawa H. Link between the ubiquitin conjugation system and the ISG15 conjugation system: ISG15 conjugation to the UbcH6 ubiquitin E2 enzyme. J Biochem 2005; 138: 711-719.
    • (2005) J Biochem , vol.138 , pp. 711-719
    • Takeuchi, T.1    Iwahara, S.2    Saeki, Y.3    Sasajima, H.4    Yokosawa, H.5
  • 36
    • 64049096198 scopus 로고    scopus 로고
    • A clathrindependent pathway leads to KRas signaling on late endosomes en route to lysosomes
    • Lu A, Tebar F, Alvarez-Moya B, Ló pez-Alcalá C, Calvo M, Enrich C et al. A clathrindependent pathway leads to KRas signaling on late endosomes en route to lysosomes. J Cell Biol 2009; 184: 863-879.
    • (2009) J Cell Biol , vol.184 , pp. 863-879
    • Lu, A.1    Tebar, F.2    Alvarez-Moya, B.3    Ló Pez-Alcala, C.4    Calvo, M.5    Enrich, C.6
  • 37
    • 0031593675 scopus 로고    scopus 로고
    • Bafilomycin A1 prevents maturation of autophagic vacuoles by inhibiting fusion between autophagosomes and lysosomes in rat hepatoma cell line, H-4-II-E cells
    • Yamamoto A, Tagawa Y, Yoshimori T, Moriyama Y, Masaki R, Tashiro Y. Bafilomycin A1 prevents maturation of autophagic vacuoles by inhibiting fusion between autophagosomes and lysosomes in rat hepatoma cell line, H-4-II-E cells. Cell Struct Funct 1998; 23: 33-42.
    • (1998) Cell Struct Funct , vol.23 , pp. 33-42
    • Yamamoto, A.1    Tagawa, Y.2    Yoshimori, T.3    Moriyama, Y.4    Masaki, R.5    Tashiro, Y.6
  • 38
    • 0034614637 scopus 로고    scopus 로고
    • The hallmarks of cancer
    • Hanahan D, Weinberg RA. The hallmarks of cancer. Cell 2000; 100: 57-70.
    • (2000) Cell , vol.100 , pp. 57-70
    • Hanahan, D.1    Weinberg, R.A.2
  • 39
    • 79952284127 scopus 로고    scopus 로고
    • Hallmarks of cancer: The next generation
    • Hanahan D, Weinberg RA. Hallmarks of cancer: the next generation. Cell 2011; 144: 646-674.
    • (2011) Cell , vol.144 , pp. 646-674
    • Hanahan, D.1    Weinberg, R.A.2
  • 40
    • 0037007430 scopus 로고    scopus 로고
    • Ras-inducible immortalized fibroblasts: Focus formation without cell cycle deregulation
    • Jacobsen K, Groth A, Willumsen BM. Ras-inducible immortalized fibroblasts: focus formation without cell cycle deregulation. Oncogene 2002; 21: 3058-3067.
    • (2002) Oncogene , vol.21 , pp. 3058-3067
    • Jacobsen, K.1    Groth, A.2    Willumsen, B.M.3
  • 41
    • 54549102284 scopus 로고    scopus 로고
    • Derailed endocytosis: An emerging feature of cancer
    • Mosesson Y, Mills GB, Yarden Y. Derailed endocytosis: an emerging feature of cancer. Nat Rev Cancer 2008; 8: 835-850.
    • (2008) Nat Rev Cancer , vol.8 , pp. 835-850
    • Mosesson, Y.1    Mills, G.B.2    Yarden, Y.3
  • 42
    • 33749024777 scopus 로고    scopus 로고
    • Reassessing epithelial to mesenchymal transition as a prerequisite for carcinoma invasion and metastasis
    • Christiansen JJ, Rajasekaran AK. Reassessing epithelial to mesenchymal transition as a prerequisite for carcinoma invasion and metastasis. Cancer Res 2006; 66: 8319-8326.
    • (2006) Cancer Res , vol.66 , pp. 8319-8326
    • Christiansen, J.J.1    Rajasekaran, A.K.2
  • 43
    • 0033615002 scopus 로고    scopus 로고
    • Tumourassociated E-cadherin mutations alter cellular morphology, decrease cellular adhesion and increase cellular motility
    • Handschuh G, Candidus S, Luber B, Reich U, Schott C, Oswald S et al. Tumourassociated E-cadherin mutations alter cellular morphology, decrease cellular adhesion and increase cellular motility. Oncogene 1999; 18: 4301-4312.
    • (1999) Oncogene , vol.18 , pp. 4301-4312
    • Handschuh, G.1    Candidus, S.2    Luber, B.3    Reich, U.4    Schott, C.5    Oswald, S.6
  • 44
    • 4644273687 scopus 로고    scopus 로고
    • The role of Rho GTPases in the regulation of the rearrangement of actin cytoskeleton and cell movement
    • Begum R, Nur EKMS, Zaman MA. The role of Rho GTPases in the regulation of the rearrangement of actin cytoskeleton and cell movement. Exp Mol Med 2004; 36: 358-366.
    • (2004) Exp Mol Med , vol.36 , pp. 358-366
    • Begum, R.1    Nur, E.K.M.S.2    Zaman, M.A.3
  • 48
    • 57149092129 scopus 로고    scopus 로고
    • Ras signaling influences permissiveness of malignant peripheral nerve sheath tumor cells to oncolytic herpes
    • Farassati F, Bell SM, Sagar P, Blair GE, Dixon MF, Quirke P. Ras signaling influences permissiveness of malignant peripheral nerve sheath tumor cells to oncolytic herpes. Am J Pathol 2008; 173: 1861-1872.
    • (2008) Am J Pathol , vol.173 , pp. 1861-1872
    • Farassati, F.1    Bell, S.M.2    Sagar, P.3    Blair, G.E.4    Dixon, M.F.5    Quirke, P.6
  • 49
    • 33645325937 scopus 로고    scopus 로고
    • CHMP5 is essential for late endosome function and down-regulation of receptor signaling during mouse embryogenesis
    • Shim JH, Xiao C, Hayden MS, Lee KY, Trombetta ES, Pypaert M et al. CHMP5 is essential for late endosome function and down-regulation of receptor signaling during mouse embryogenesis. J Cell Biol 2006; 172: 1045-1056.
    • (2006) J Cell Biol , vol.172 , pp. 1045-1056
    • Shim, J.H.1    Xiao, C.2    Hayden, M.S.3    Lee, K.Y.4    Trombetta, E.S.5    Pypaert, M.6
  • 50
    • 77950839509 scopus 로고    scopus 로고
    • The interferon-induced gene ISG15 blocks retrovirus release from cells late in the budding process
    • Pincetic A, Kuang Z, Seo EJ, Leis J. The interferon-induced gene ISG15 blocks retrovirus release from cells late in the budding process. J Virol 2011; 84: 4725-4736.
    • (2011) J Virol , vol.84 , pp. 4725-4736
    • Pincetic, A.1    Kuang, Z.2    Seo, E.J.3    Leis, J.4
  • 51
    • 79960406323 scopus 로고    scopus 로고
    • Mechanism of inhibition of retrovirus release from cells by interferon-induced gene ISG15
    • Kuang Z, Seo EJ, Leis J. Mechanism of inhibition of retrovirus release from cells by interferon-induced gene ISG15. J Virol 2011; 85: 7153-7161.
    • (2011) J Virol , vol.85 , pp. 7153-7161
    • Kuang, Z.1    Seo, E.J.2    Leis, J.3
  • 52
    • 15444369744 scopus 로고    scopus 로고
    • The role of LIP5 and CHMP5 in multivesicular body formation and HIV-1 budding in mammalian cells
    • Ward DM, Vaughn MB, Shiflett SL, White PL, Pollock AL, Hill J et al. The role of LIP5 and CHMP5 in multivesicular body formation and HIV-1 budding in mammalian cells. J Biol Chem 2005; 280: 10548-10555.
    • (2005) J Biol Chem , vol.280 , pp. 10548-10555
    • Ward, D.M.1    Vaughn, M.B.2    Shiflett, S.L.3    White, P.L.4    Pollock, A.L.5    Hill, J.6
  • 53
    • 58049205735 scopus 로고    scopus 로고
    • Deficiency of a potential 3p21.3 tumor suppressor gene UBE1L (UBA7) does not accelerate lung cancer development in K-rasLA2 mice
    • Yin X, Cong X, Yan M, Zhang DE. Deficiency of a potential 3p21.3 tumor suppressor gene UBE1L (UBA7) does not accelerate lung cancer development in K-rasLA2 mice. Lung Cancer 2009; 63: 194-200.
    • (2009) Lung Cancer , vol.63 , pp. 194-200
    • Yin, X.1    Cong, X.2    Yan, M.3    Zhang, D.E.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.