-
1
-
-
0037264633
-
Targeting RAS signalling pathways in cancer therapy
-
Downward J: Targeting RAS signalling pathways in cancer therapy. Nat Rev Cancer 2003, 3:11-22
-
(2003)
Nat Rev Cancer
, vol.3
, pp. 11-22
-
-
Downward, J.1
-
2
-
-
0038311995
-
Ras family signaling: Therapeutic targeting
-
Cox AD, Der CJ: Ras family signaling: therapeutic targeting. Cancer Biol Ther 2002, 1:599-606
-
(2002)
Cancer Biol Ther
, vol.1
, pp. 599-606
-
-
Cox, A.D.1
Der, C.J.2
-
3
-
-
1242340431
-
Oncogenic Ras and its role in tumor cell invasion and metastasis
-
Campbell PM, Der CJ: Oncogenic Ras and its role in tumor cell invasion and metastasis. Semin Cancer Biol 2004, 14:105-114
-
(2004)
Semin Cancer Biol
, vol.14
, pp. 105-114
-
-
Campbell, P.M.1
Der, C.J.2
-
4
-
-
1642556736
-
Raf pathway inhibitors in oncology
-
Bollag G, Freeman S, Lyons JF, Post LE: Raf pathway inhibitors in oncology. Curr Opin Investig Drugs 2003, 4:1436-1441
-
(2003)
Curr Opin Investig Drugs
, vol.4
, pp. 1436-1441
-
-
Bollag, G.1
Freeman, S.2
Lyons, J.F.3
Post, L.E.4
-
5
-
-
0034793640
-
Ras inhibitors and radiation therapy
-
Jones HA, Hahn SM, Bernhard E, McKenna WG: Ras inhibitors and radiation therapy. Semin Radiat Oncol 2001, 11:328-337
-
(2001)
Semin Radiat Oncol
, vol.11
, pp. 328-337
-
-
Jones, H.A.1
Hahn, S.M.2
Bernhard, E.3
McKenna, W.G.4
-
6
-
-
3042742432
-
-
Eckert LB, Repasky GA, Ulku AS, McFall A, Zhou H, Sartor CI, Der CJ: Involvement of Ras activation in human breast cancer cell signaling, invasion, and anoikis. Cancer Res 2004, 64:4585-4592
-
Eckert LB, Repasky GA, Ulku AS, McFall A, Zhou H, Sartor CI, Der CJ: Involvement of Ras activation in human breast cancer cell signaling, invasion, and anoikis. Cancer Res 2004, 64:4585-4592
-
-
-
-
7
-
-
0033861175
-
Ras activation in human breast cancer
-
von Lintig FC, Dreilinger AD, Varki NM, Wallace AM, Casteel DE, Boss GR: Ras activation in human breast cancer. Breast Cancer Res Treat 2000, 62:51-62
-
(2000)
Breast Cancer Res Treat
, vol.62
, pp. 51-62
-
-
von Lintig, F.C.1
Dreilinger, A.D.2
Varki, N.M.3
Wallace, A.M.4
Casteel, D.E.5
Boss, G.R.6
-
8
-
-
0035220605
-
Biological and clinical significance of HER2 overexpression in breast cancer
-
Kurebayashi J: Biological and clinical significance of HER2 overexpression in breast cancer. Breast Cancer 2001, 8:45-51
-
(2001)
Breast Cancer
, vol.8
, pp. 45-51
-
-
Kurebayashi, J.1
-
9
-
-
0037306387
-
Inhibiting Ras signaling in the therapy of breast cancer
-
Li T, Sparano JA: Inhibiting Ras signaling in the therapy of breast cancer. Clin Breast Cancer 2003, 3:405-420
-
(2003)
Clin Breast Cancer
, vol.3
, pp. 405-420
-
-
Li, T.1
Sparano, J.A.2
-
10
-
-
2142658985
-
Molecular evolutionary patterns in breast cancer
-
Shackney SE, Silverman JF: Molecular evolutionary patterns in breast cancer. Adv Anat Pathol 2003, 10:278-290
-
(2003)
Adv Anat Pathol
, vol.10
, pp. 278-290
-
-
Shackney, S.E.1
Silverman, J.F.2
-
11
-
-
0037447154
-
Attenuation of Ras signaling restores androgen sensitivity to hormone-refractory C4-2 prostate cancer cells
-
Bakin RE, Gioeli D, Bissonette EA, Weber MJ: Attenuation of Ras signaling restores androgen sensitivity to hormone-refractory C4-2 prostate cancer cells. Cancer Res 2003, 63:1975-1980
-
(2003)
Cancer Res
, vol.63
, pp. 1975-1980
-
-
Bakin, R.E.1
Gioeli, D.2
Bissonette, E.A.3
Weber, M.J.4
-
12
-
-
0037447330
-
Constitutive activation of the Ras/mitogen-activated protein kinase signaling pathway promotes androgen hypersensitivity in LNCaP prostate cancer cells
-
Bakin RE, Gioeli D, Sikes RA, Bissonette EA, Weber MJ: Constitutive activation of the Ras/mitogen-activated protein kinase signaling pathway promotes androgen hypersensitivity in LNCaP prostate cancer cells. Cancer Res 2003, 63:1981-1989
-
(2003)
Cancer Res
, vol.63
, pp. 1981-1989
-
-
Bakin, R.E.1
Gioeli, D.2
Sikes, R.A.3
Bissonette, E.A.4
Weber, M.J.5
-
13
-
-
0033555967
-
Activation of mitogen-activated protein kinase associated with prostate cancer progression
-
Gioeli D, Mandell JW, Petroni GR, Frierson Jr HF, Weber MJ: Activation of mitogen-activated protein kinase associated with prostate cancer progression. Cancer Res 1999, 59:279-284
-
(1999)
Cancer Res
, vol.59
, pp. 279-284
-
-
Gioeli, D.1
Mandell, J.W.2
Petroni, G.R.3
Frierson Jr, H.F.4
Weber, M.J.5
-
14
-
-
16344382525
-
Mitogen activated protein kinase signal transduction pathways in the prostate
-
Maroni PD, Koul S, Meacham RB, Koul HK: Mitogen activated protein kinase signal transduction pathways in the prostate. Cell Commun Signal 2004, 2:5
-
(2004)
Cell Commun Signal
, vol.2
, pp. 5
-
-
Maroni, P.D.1
Koul, S.2
Meacham, R.B.3
Koul, H.K.4
-
15
-
-
0346095286
-
Activation of the Raf-1/MEK/Erk kinase pathway by a novel Cdc25 inhibitor in human prostate cancer cells
-
Nemoto K, Vogt A, Oguri T, Lazo JS: Activation of the Raf-1/MEK/Erk kinase pathway by a novel Cdc25 inhibitor in human prostate cancer cells. Prostate 2004, 58:95-102
-
(2004)
Prostate
, vol.58
, pp. 95-102
-
-
Nemoto, K.1
Vogt, A.2
Oguri, T.3
Lazo, J.S.4
-
16
-
-
3242756036
-
Ras signaling in prostate cancer progression
-
Weber MJ, Gioeli D: Ras signaling in prostate cancer progression. J Cell Biochem 2004, 91:13-25
-
(2004)
J Cell Biochem
, vol.91
, pp. 13-25
-
-
Weber, M.J.1
Gioeli, D.2
-
17
-
-
0028907463
-
Ras, p53 and HPV status in benign and malignant prostate tumors
-
Moyret-Lalle C, Marcais C, Jacquemier J, Moles JP, Daver A, Soret JY, Jeanteur P, Ozturk M, Theillet C: Ras, p53 and HPV status in benign and malignant prostate tumors. Int J Cancer 1995, 64:124-129
-
(1995)
Int J Cancer
, vol.64
, pp. 124-129
-
-
Moyret-Lalle, C.1
Marcais, C.2
Jacquemier, J.3
Moles, J.P.4
Daver, A.5
Soret, J.Y.6
Jeanteur, P.7
Ozturk, M.8
Theillet, C.9
-
18
-
-
0027476131
-
Mutational status of codons 12 and 13 of the N- and K-ras genes in tissue and cell lines derived from primary and metastatic prostate carcinomas
-
Pergolizzi RG, Kreis W, Rottach C, Susin M, Broome JD: Mutational status of codons 12 and 13 of the N- and K-ras genes in tissue and cell lines derived from primary and metastatic prostate carcinomas. Cancer Invest 1993, 11:25-32
-
(1993)
Cancer Invest
, vol.11
, pp. 25-32
-
-
Pergolizzi, R.G.1
Kreis, W.2
Rottach, C.3
Susin, M.4
Broome, J.D.5
-
19
-
-
0033572599
-
HRAS1 rare minisatellite alleles and breast cancer in Australian women under age forty years
-
Firgaira FA, Seshadri R, McEvoy CR, Dite GS, Giles GG, McCredie MR, Southey MC, Venter DJ, Hopper JL: HRAS1 rare minisatellite alleles and breast cancer in Australian women under age forty years. J Natl Cancer Inst 1999, 91:2107-2111
-
(1999)
J Natl Cancer Inst
, vol.91
, pp. 2107-2111
-
-
Firgaira, F.A.1
Seshadri, R.2
McEvoy, C.R.3
Dite, G.S.4
Giles, G.G.5
McCredie, M.R.6
Southey, M.C.7
Venter, D.J.8
Hopper, J.L.9
-
20
-
-
0034901122
-
Phase I trial of ISIS 5132, an antisense oligonucleotide inhibitor of c-raf-1, administered by 24-hour weekly infusion to patients with advanced cancer
-
Rudin CM, Holmlund J, Fleming GF, Mani S, Stadler WM, Schumm P, Monia BP, Johnston JF, Geary R, Yu RZ, Kwoh TJ, Dorr FA, Ratain MJ: Phase I trial of ISIS 5132, an antisense oligonucleotide inhibitor of c-raf-1, administered by 24-hour weekly infusion to patients with advanced cancer. Clin Cancer Res 2001, 7:1214-1220
-
(2001)
Clin Cancer Res
, vol.7
, pp. 1214-1220
-
-
Rudin, C.M.1
Holmlund, J.2
Fleming, G.F.3
Mani, S.4
Stadler, W.M.5
Schumm, P.6
Monia, B.P.7
Johnston, J.F.8
Geary, R.9
Yu, R.Z.10
Kwoh, T.J.11
Dorr, F.A.12
Ratain, M.J.13
-
21
-
-
0026521070
-
Aberrant regulation of ras proteins in malignant tumour cells from type 1 neurofibromatosis patients
-
Basu TN, Gutmann DH, Fletcher JA, Glover TW, Collins FS, Downward J: Aberrant regulation of ras proteins in malignant tumour cells from type 1 neurofibromatosis patients. Nature 1992, 356:713-715
-
(1992)
Nature
, vol.356
, pp. 713-715
-
-
Basu, T.N.1
Gutmann, D.H.2
Fletcher, J.A.3
Glover, T.W.4
Collins, F.S.5
Downward, J.6
-
22
-
-
0035936783
-
NF1 tumor suppressor gene function: Narrowing the GAP
-
Cichowski K, Jacks T: NF1 tumor suppressor gene function: narrowing the GAP. Cell 2001, 104:593-604
-
(2001)
Cell
, vol.104
, pp. 593-604
-
-
Cichowski, K.1
Jacks, T.2
-
24
-
-
2942576587
-
Sulindac derivatives inhibit cell growth and induce apoptosis in primary cells from malignant peripheral nerve sheath tumors of NF1-patients
-
Frahm S, Kurtz A, Kluwe L, Farassati F, Friedrich RE, Mautner VF: Sulindac derivatives inhibit cell growth and induce apoptosis in primary cells from malignant peripheral nerve sheath tumors of NF1-patients. Cancer Cell Int 2004, 4:4
-
(2004)
Cancer Cell Int
, vol.4
, pp. 4
-
-
Frahm, S.1
Kurtz, A.2
Kluwe, L.3
Farassati, F.4
Friedrich, R.E.5
Mautner, V.F.6
-
25
-
-
0033605452
-
Pathology of tumors of the peripheral nerve sheath in type 1 neurofibromatosis
-
Woodruff JM: Pathology of tumors of the peripheral nerve sheath in type 1 neurofibromatosis. Am J Med Genet 1999, 89:23-30
-
(1999)
Am J Med Genet
, vol.89
, pp. 23-30
-
-
Woodruff, J.M.1
-
26
-
-
13944279517
-
Ras/Raf/ERK signalling and NF1
-
Harrisingh MC, Lloyd AC: Ras/Raf/ERK signalling and NF1. Cell Cycle 2004, 3:1255-1258
-
(2004)
Cell Cycle
, vol.3
, pp. 1255-1258
-
-
Harrisingh, M.C.1
Lloyd, A.C.2
-
27
-
-
0030992545
-
A double-stranded RNA-activated protein kinase-dependent pathway mediating stress-induced apoptosis
-
Der SD, Yang YL, Weissmann C, Williams BR: A double-stranded RNA-activated protein kinase-dependent pathway mediating stress-induced apoptosis. Proc Natl Acad Sci USA 1997, 94:3279-3283
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 3279-3283
-
-
SD, D.1
Yang, Y.L.2
Weissmann, C.3
Williams, B.R.4
-
29
-
-
0035075794
-
Neurofibromatosis 1 (NF1) heterozygosity results in a cell-autonomous growth advantage for astrocytes
-
Bajenaru ML, Donahoe J, Corral T, Reilly KM, Brophy S, Pellicer A, Gutmann DH: Neurofibromatosis 1 (NF1) heterozygosity results in a cell-autonomous growth advantage for astrocytes. Glia 2001, 33:314-323
-
(2001)
Glia
, vol.33
, pp. 314-323
-
-
Bajenaru, M.L.1
Donahoe, J.2
Corral, T.3
Reilly, K.M.4
Brophy, S.5
Pellicer, A.6
Gutmann, D.H.7
-
30
-
-
0034730635
-
Single cell Ras-GTP analysis reveals altered Ras activity in a subpopulation of neurofibroma Schwann cells but not fibroblasts
-
Sherman LS, Atit R, Rosenbaum T, Cox AD, Ratner N: Single cell Ras-GTP analysis reveals altered Ras activity in a subpopulation of neurofibroma Schwann cells but not fibroblasts. J Biol Chem 2000, 275:30740-30745
-
(2000)
J Biol Chem
, vol.275
, pp. 30740-30745
-
-
Sherman, L.S.1
Atit, R.2
Rosenbaum, T.3
Cox, A.D.4
Ratner, N.5
-
31
-
-
0030850675
-
Confirmation of a double-hit model for the NF1 gene in benign neurofibromas
-
Serra E, Puig S, Otero D, Gaona A, Kruyer H, Ars E, Estivill X, Lazaro C: Confirmation of a double-hit model for the NF1 gene in benign neurofibromas. Am J Hum Genet 1997, 61:512-519
-
(1997)
Am J Hum Genet
, vol.61
, pp. 512-519
-
-
Serra, E.1
Puig, S.2
Otero, D.3
Gaona, A.4
Kruyer, H.5
Ars, E.6
Estivill, X.7
Lazaro, C.8
-
32
-
-
0025108408
-
Chromosome 17p deletions and p53 gene mutations associated with the formation of malignant neurofibrosarcomas in von Recklinghausen neurofibromatosis
-
Menon AG, Anderson KM, Riccardi VM, Chung RY, Whaley JM, Yandell DW, Farmer GE, Freiman RN, Lee JK, Li FP: Chromosome 17p deletions and p53 gene mutations associated with the formation of malignant neurofibrosarcomas in von Recklinghausen neurofibromatosis. Proc Natl Acad Sci USA 1990, 87:5435-5439
-
(1990)
Proc Natl Acad Sci USA
, vol.87
, pp. 5435-5439
-
-
Menon, A.G.1
Anderson, K.M.2
Riccardi, V.M.3
Chung, R.Y.4
Whaley, J.M.5
Yandell, D.W.6
Farmer, G.E.7
Freiman, R.N.8
Lee, J.K.9
Li, F.P.10
-
33
-
-
0028146806
-
TP53 mutations are frequent in malignant NF1 tumors
-
Legius E, Dierick H, Wu R, Hall BK, Marynen P, Cassiman JJ, Glover TW: TP53 mutations are frequent in malignant NF1 tumors. Genes Chromosom Cancer 1994, 10:250-255
-
(1994)
Genes Chromosom Cancer
, vol.10
, pp. 250-255
-
-
Legius, E.1
Dierick, H.2
Wu, R.3
Hall, B.K.4
Marynen, P.5
Cassiman, J.J.6
Glover, T.W.7
-
34
-
-
0026969093
-
Cytogenetics and molecular genetics of nervous system tumors
-
Rey JA, Pestana A, Bello MJ: Cytogenetics and molecular genetics of nervous system tumors. Oncol Res 1992, 4:321-331
-
(1992)
Oncol Res
, vol.4
, pp. 321-331
-
-
Rey, J.A.1
Pestana, A.2
Bello, M.J.3
-
35
-
-
0032786494
-
Mouse tumor model for neurofibromatosis type 1
-
Vogel KS, Klesse LJ, Velasco-Miguel S, Meyers K, Rushing EJ, Parada LF: Mouse tumor model for neurofibromatosis type 1. Science 1999, 286:2176-2179
-
(1999)
Science
, vol.286
, pp. 2176-2179
-
-
Vogel, K.S.1
Klesse, L.J.2
Velasco-Miguel, S.3
Meyers, K.4
Rushing, E.J.5
Parada, L.F.6
-
36
-
-
0032763861
-
Mouse models of tumor development in neurofibromatosis type 1
-
Cichowski K, Shih TS, Schmitt E, Santiago S, Reilly K, McLaughlin ME, Bronson RT, Jacks T: Mouse models of tumor development in neurofibromatosis type 1. Science 1999, 286:2172-2176
-
(1999)
Science
, vol.286
, pp. 2172-2176
-
-
Cichowski, K.1
Shih, T.S.2
Schmitt, E.3
Santiago, S.4
Reilly, K.5
McLaughlin, M.E.6
Bronson, R.T.7
Jacks, T.8
-
37
-
-
0029023868
-
Attenuated multi-mutated herpes simplex virus-1 for the treatment of malignant gliomas
-
Mineta T, Rabkin SD, Yazaki T, Hunter WD, Martuza RL: Attenuated multi-mutated herpes simplex virus-1 for the treatment of malignant gliomas. Nat Med 1995, 1:938-943
-
(1995)
Nat Med
, vol.1
, pp. 938-943
-
-
Mineta, T.1
Rabkin, S.D.2
Yazaki, T.3
Hunter, W.D.4
Martuza, R.L.5
-
38
-
-
12944315014
-
Conditionally replicating herpes simplex virus mutant. G207 for the treatment of malignant glioma: Results of a phase I trial
-
Markert JM, Medlock MD, Rabkin SD, Gillespie GY, Todo T, Hunter WD, Palmer CA, Feigenbaum F, Tornatore C, Tufaro F, Martuza RL: Conditionally replicating herpes simplex virus mutant. G207 for the treatment of malignant glioma: results of a phase I trial. Gene Ther 2000, 7:867-874
-
(2000)
Gene Ther
, vol.7
, pp. 867-874
-
-
Markert, J.M.1
Medlock, M.D.2
Rabkin, S.D.3
Gillespie, G.Y.4
Todo, T.5
Hunter, W.D.6
Palmer, C.A.7
Feigenbaum, F.8
Tornatore, C.9
Tufaro, F.10
Martuza, R.L.11
-
39
-
-
0035004186
-
Therapeutic efficacy of G207 in a novel peripheral nerve sheath tumor model
-
Mashour GA, Moulding HD, Chahlavi A, Khan GA, Rabkin SD, Martuza RL, Driever PH, Kurtz A: Therapeutic efficacy of G207 in a novel peripheral nerve sheath tumor model. Exp Neurol 2001, 169:64-71
-
(2001)
Exp Neurol
, vol.169
, pp. 64-71
-
-
Mashour, G.A.1
Moulding, H.D.2
Chahlavi, A.3
Khan, G.A.4
Rabkin, S.D.5
Martuza, R.L.6
Driever, P.H.7
Kurtz, A.8
-
40
-
-
1542752969
-
Ras signalling pathway: A gateway for HSV-1 infection
-
Farassati F, Lee PW: Ras signalling pathway: a gateway for HSV-1 infection. Sci World J 2003, 3:533-535
-
(2003)
Sci World J
, vol.3
, pp. 533-535
-
-
Farassati, F.1
Lee, P.W.2
-
41
-
-
0034910459
-
Oncogenes in Ras signalling pathway dictate host-cell permissiveness to herpes simplex virus 1
-
Farassati F, Yang AD, Lee PW: Oncogenes in Ras signalling pathway dictate host-cell permissiveness to herpes simplex virus 1. Nat Cell Biol 2001, 3:745-750
-
(2001)
Nat Cell Biol
, vol.3
, pp. 745-750
-
-
Farassati, F.1
Yang, A.D.2
Lee, P.W.3
-
42
-
-
0032515141
-
Reovirus therapy of tumors with activated Ras pathway
-
Coffey MC, Strong JE, Forsyth PA, Lee PW: Reovirus therapy of tumors with activated Ras pathway. Science 1998, 282:1332-1334
-
(1998)
Science
, vol.282
, pp. 1332-1334
-
-
Coffey, M.C.1
Strong, J.E.2
Forsyth, P.A.3
Lee, P.W.4
-
43
-
-
0036210203
-
Reovirus oncolysis of human breast cancer
-
Norman KL, Coffey MC, Hirasawa K, Demetrick DJ, Nishikawa SG, DiFrancesco LM, Strong JE, Lee PW: Reovirus oncolysis of human breast cancer. Hum Gene Ther 2002, 13:641-652
-
(2002)
Hum Gene Ther
, vol.13
, pp. 641-652
-
-
Norman, K.L.1
Coffey, M.C.2
Hirasawa, K.3
Demetrick, D.J.4
Nishikawa, S.G.5
DiFrancesco, L.M.6
Strong, J.E.7
Lee, P.W.8
-
44
-
-
0032526693
-
The molecular basis of viral oncolysis: Usurpation of the Ras signaling pathway by reovirus
-
Strong JE, Coffey MC, Tang D, Sabinin P, Lee PW: The molecular basis of viral oncolysis: usurpation of the Ras signaling pathway by reovirus. EMBO J 1998, 17:3351-3362
-
(1998)
EMBO J
, vol.17
, pp. 3351-3362
-
-
Strong, J.E.1
Coffey, M.C.2
Tang, D.3
Sabinin, P.4
Lee, P.W.5
-
45
-
-
2342641505
-
Mitogen-activated protein kinase signaling
-
Kyosseva SV: Mitogen-activated protein kinase signaling. Int Rev Neurobiol 2004, 59:201-220
-
(2004)
Int Rev Neurobiol
, vol.59
, pp. 201-220
-
-
Kyosseva, S.V.1
-
46
-
-
1342321750
-
PI 3-kinase, Akt and cell survival
-
Downward J: PI 3-kinase, Akt and cell survival. Semin Cell Dev Biol 2004, 15:177-182
-
(2004)
Semin Cell Dev Biol
, vol.15
, pp. 177-182
-
-
Downward, J.1
-
47
-
-
0028074316
-
-
Rodriguez-Viciana P, Warne PH, Dhand R, Vanhaesebroeck B, Gout I, Fry MJ, Waterfield MD, Downward J: Phosphatidylinositol-3-OH kinase as a direct target of Ras. Nature 1994, 370:527-532
-
Rodriguez-Viciana P, Warne PH, Dhand R, Vanhaesebroeck B, Gout I, Fry MJ, Waterfield MD, Downward J: Phosphatidylinositol-3-OH kinase as a direct target of Ras. Nature 1994, 370:527-532
-
-
-
-
48
-
-
0034992141
-
Ras activation of phosphatidylinositol 3-kinase and Akt
-
Rodriguez-Viciana P, Downward J: Ras activation of phosphatidylinositol 3-kinase and Akt. Methods Enzymol 2001, 333:37-44
-
(2001)
Methods Enzymol
, vol.333
, pp. 37-44
-
-
Rodriguez-Viciana, P.1
Downward, J.2
-
49
-
-
0035067274
-
p53 is dispensable for UV-induced cell cycle arrest at late G(1) in mammalian cells
-
Al-Mohanna MA, Al-Khodairy FM, Krezolek Z, Bertilsson PA, Al-Houssein KA, Aboussekhra A: p53 is dispensable for UV-induced cell cycle arrest at late G(1) in mammalian cells. Carcinogenesis 2001, 22:573-578
-
(2001)
Carcinogenesis
, vol.22
, pp. 573-578
-
-
Al-Mohanna, M.A.1
Al-Khodairy, F.M.2
Krezolek, Z.3
Bertilsson, P.A.4
Al-Houssein, K.A.5
Aboussekhra, A.6
-
50
-
-
0036615657
-
p53-independent apoptosis in UV-irradiated mouse skin: Possible inhibition by 50 Hz magnetic fields
-
Kumlin T, Heikkinen P, Kosma VM, Alhonen L, Janne J, Juutilainen J: p53-independent apoptosis in UV-irradiated mouse skin: possible inhibition by 50 Hz magnetic fields. Radiat Environ Biophys 2002, 41:155-158
-
(2002)
Radiat Environ Biophys
, vol.41
, pp. 155-158
-
-
Kumlin, T.1
Heikkinen, P.2
Kosma, V.M.3
Alhonen, L.4
Janne, J.5
Juutilainen, J.6
-
51
-
-
0028349997
-
Targeted disruption of the neurofibromatosis type-1 gene leads to developmental abnormalities in heart and various neural crest-derived tissues
-
Brannan CI, Perkins AS, Vogel KS, Ratner N, Nordlund ML, Reid SW, Buchberg AM, Jenkins NA, Parada LF, Copeland NG: Targeted disruption of the neurofibromatosis type-1 gene leads to developmental abnormalities in heart and various neural crest-derived tissues. Genes Dev 1994, 8:1019-1029
-
(1994)
Genes Dev
, vol.8
, pp. 1019-1029
-
-
Brannan, C.I.1
Perkins, A.S.2
Vogel, K.S.3
Ratner, N.4
Nordlund, M.L.5
Reid, S.W.6
Buchberg, A.M.7
Jenkins, N.A.8
Parada, L.F.9
Copeland, N.G.10
-
52
-
-
0034734607
-
Molecular assembly of mitogen-activated protein kinase module in ras-transformed NIH3T3 cell line
-
Park KS, Kim JA, Chai KJ: Molecular assembly of mitogen-activated protein kinase module in ras-transformed NIH3T3 cell line. Exp Mol Med 2000, 32:120-126
-
(2000)
Exp Mol Med
, vol.32
, pp. 120-126
-
-
Park, K.S.1
Kim, J.A.2
Chai, K.J.3
-
53
-
-
0027210909
-
Antibodies to human papillomavirus and to other genital infectious agents and invasive cervical cancer risk
-
Jha PK, Beral V, Peto J, Hack S, Hermon C, Deacon J, Mant D, Chilvers C, Vessey MP, Pike MC: Antibodies to human papillomavirus and to other genital infectious agents and invasive cervical cancer risk. Lancet 1993, 341:1116-1118
-
(1993)
Lancet
, vol.341
, pp. 1116-1118
-
-
Jha, P.K.1
Beral, V.2
Peto, J.3
Hack, S.4
Hermon, C.5
Deacon, J.6
Mant, D.7
Chilvers, C.8
Vessey, M.P.9
Pike, M.C.10
-
54
-
-
0030861015
-
Cellular ras gene activity is required for full neoplastic transformation by the large tumor antigen of SV40
-
Raptis L, Brownell HL, Corbley MJ, Wood KW, Wang D, Haliotis T: Cellular ras gene activity is required for full neoplastic transformation by the large tumor antigen of SV40. Cell Growth Differ 1997, 8:891-901
-
(1997)
Cell Growth Differ
, vol.8
, pp. 891-901
-
-
Raptis, L.1
Brownell, H.L.2
Corbley, M.J.3
Wood, K.W.4
Wang, D.5
Haliotis, T.6
-
55
-
-
0035958881
-
Simian virus 40 large tumor antigen modulates the Raf signaling pathway
-
Grammatikakis N, Jaronczyk K, Siganou A, Vultur A, Brownell HL, Benzaquen M, Rausch C, Lapointe R, Gjoerup O, Roberts TM, Raptis L: Simian virus 40 large tumor antigen modulates the Raf signaling pathway. J Biol Chem 2001, 276:27840-27845
-
(2001)
J Biol Chem
, vol.276
, pp. 27840-27845
-
-
Grammatikakis, N.1
Jaronczyk, K.2
Siganou, A.3
Vultur, A.4
Brownell, H.L.5
Benzaquen, M.6
Rausch, C.7
Lapointe, R.8
Gjoerup, O.9
Roberts, T.M.10
Raptis, L.11
-
56
-
-
0031309798
-
Mammalian MAP kinase modules: How to transduce specific signals
-
Brunet A, Pouyssegur J: Mammalian MAP kinase modules: how to transduce specific signals. Essays Biochem 1997, 32:1-16
-
(1997)
Essays Biochem
, vol.32
, pp. 1-16
-
-
Brunet, A.1
Pouyssegur, J.2
-
57
-
-
0032541650
-
Increasing complexity of Ras signaling
-
Campbell SL, Khosravi-Far R, Rossman KL, Clark GJ, Der CJ: Increasing complexity of Ras signaling. Oncogene 1998, 17:1395-1413
-
(1998)
Oncogene
, vol.17
, pp. 1395-1413
-
-
Campbell, S.L.1
Khosravi-Far, R.2
Rossman, K.L.3
Clark, G.J.4
Der, C.J.5
-
58
-
-
0032928614
-
Mitogen-activated protein kinase: Conservation of a three-kinase module from yeast to human
-
Widmann C, Gibson S, Jarpe MB, Johnson GL: Mitogen-activated protein kinase: conservation of a three-kinase module from yeast to human. Physiol Rev 1999, 79:143-180
-
(1999)
Physiol Rev
, vol.79
, pp. 143-180
-
-
Widmann, C.1
Gibson, S.2
Jarpe, M.B.3
Johnson, G.L.4
-
59
-
-
0028229012
-
The stress-activated protein kinase subfamily of c-Jun kinases
-
Kyriakis JM, Banerjee P, Nikolakaki E, Dai T, Rubie EA, Ahmad MF, Avruch J, Woodgett JR: The stress-activated protein kinase subfamily of c-Jun kinases. Nature 1994, 369:156-160
-
(1994)
Nature
, vol.369
, pp. 156-160
-
-
Kyriakis, J.M.1
Banerjee, P.2
Nikolakaki, E.3
Dai, T.4
Rubie, E.A.5
Ahmad, M.F.6
Avruch, J.7
Woodgett, J.R.8
-
60
-
-
0342758711
-
p38 MAPK signalling cascades: Ancient roles and new functions
-
Martín-Blanco E: p38 MAPK signalling cascades: ancient roles and new functions. Bioessays 2000, 22:637-645
-
(2000)
Bioessays
, vol.22
, pp. 637-645
-
-
Martín-Blanco, E.1
-
61
-
-
0030765077
-
Stress-activated protein kinases: Activation, regulation and function
-
Paul A, Wilson S, Belham CM, Robinson CJ, Scott PH, Gould GW, Plevin R: Stress-activated protein kinases: activation, regulation and function. Cell Signal 1997, 9:403-410
-
(1997)
Cell Signal
, vol.9
, pp. 403-410
-
-
Paul, A.1
Wilson, S.2
Belham, C.M.3
Robinson, C.J.4
Scott, P.H.5
Gould, G.W.6
Plevin, R.7
-
62
-
-
0033545565
-
Differential contribution of the ERK and JNK mitogen-activated protein kinase cascades to Ras transformation of HT1080 fibrosarcoma and DLD-1 colon carcinoma cells
-
Plattner R, Gupta S, Khosravi-Far R, Sato KY, Perucho M, Der CJ, Stanbridge EJ: Differential contribution of the ERK and JNK mitogen-activated protein kinase cascades to Ras transformation of HT1080 fibrosarcoma and DLD-1 colon carcinoma cells. Oncogene 1999, 18:1807-1817
-
(1999)
Oncogene
, vol.18
, pp. 1807-1817
-
-
Plattner, R.1
Gupta, S.2
Khosravi-Far, R.3
Sato, K.Y.4
Perucho, M.5
CJ, D.6
Stanbridge, E.J.7
-
63
-
-
0030605386
-
Phosphatidylinositol 3 kinase: One of the effectors of Ras
-
Rodriguez-Viciana P, Marte BM, Warne PH, Downward J: Phosphatidylinositol 3 kinase: one of the effectors of Ras. Philos Trans R Soc Lond B Biol Sci 1996, 351:222-231
-
(1996)
Philos Trans R Soc Lond B Biol Sci
, vol.351
, pp. 222-231
-
-
Rodriguez-Viciana, P.1
Marte, B.M.2
Warne, P.H.3
Downward, J.4
-
64
-
-
0032515027
-
Regulation of cell death protease caspase-9 by phosphorylation
-
Cardone MH, Roy N, Stennicke HR, Salvesen GS, Franke TF, Stanbridge E, Frisch S, Reed JC: Regulation of cell death protease caspase-9 by phosphorylation. Science 1998, 282:1318-1321
-
(1998)
Science
, vol.282
, pp. 1318-1321
-
-
Cardone, M.H.1
Roy, N.2
Stennicke, H.R.3
Salvesen, G.S.4
Franke, T.F.5
Stanbridge, E.6
Frisch, S.7
Reed, J.C.8
-
65
-
-
0033083796
-
Neurofibromatosis type 1 peripheral nerve tumors: Aberrant activation of the Ras pathway
-
Feldkamp MM, Angelov L, Guha A: Neurofibromatosis type 1 peripheral nerve tumors: aberrant activation of the Ras pathway. Surg Neurol 1999, 51:211-218
-
(1999)
Surg Neurol
, vol.51
, pp. 211-218
-
-
Feldkamp, M.M.1
Angelov, L.2
Guha, A.3
-
68
-
-
0034924357
-
Oncolytic viruses as therapeutic agents
-
Wildner O: Oncolytic viruses as therapeutic agents. Ann Med 2001, 33:291-304
-
(2001)
Ann Med
, vol.33
, pp. 291-304
-
-
Wildner, O.1
-
69
-
-
0030897659
-
Evaluation of genetically engineered herpes simplex viruses as oncolytic agents for human malignant brain tumors
-
Andreansky S, Soroceanu L, Flotte ER, Chou J, Markert JM, Gillespie GY, Roizman B, Whitley RJ: Evaluation of genetically engineered herpes simplex viruses as oncolytic agents for human malignant brain tumors. Cancer Res 1997, 57:1502-1509
-
(1997)
Cancer Res
, vol.57
, pp. 1502-1509
-
-
Andreansky, S.1
Soroceanu, L.2
Flotte, E.R.3
Chou, J.4
Markert, J.M.5
Gillespie, G.Y.6
Roizman, B.7
Whitley, R.J.8
-
70
-
-
0034780803
-
Ionizing radiation does not alter the antitumor activity of herpes simplex virus vector g207 in subcutaneous tumor models of human and murine prostate cancer
-
Jorgensen TJ, Katz S, Wittmack EK, Varghese S, Todo T, Rabkin SD, Martuza RL: Ionizing radiation does not alter the antitumor activity of herpes simplex virus vector g207 in subcutaneous tumor models of human and murine prostate cancer. Neoplasia 2001, 3:451-456
-
(2001)
Neoplasia
, vol.3
, pp. 451-456
-
-
Jorgensen, T.J.1
Katz, S.2
Wittmack, E.K.3
Varghese, S.4
Todo, T.5
Rabkin, S.D.6
Martuza, R.L.7
-
71
-
-
0032789088
-
Attenuated, replication-competent herpes simplex virus type 1 mutant G207: Safety evaluation of intracerebral injection in nonhuman primates
-
Hunter WD, Martuza RL, Feigenbaum F, Todo T, Mineta T, Yazaki T, Toda M, Newsome JT, Platenberg RC, Manz HJ, Rabkin SD: Attenuated, replication-competent herpes simplex virus type 1 mutant G207: safety evaluation of intracerebral injection in nonhuman primates. J Virol 1999, 73:6319-6326
-
(1999)
J Virol
, vol.73
, pp. 6319-6326
-
-
Hunter, W.D.1
Martuza, R.L.2
Feigenbaum, F.3
Todo, T.4
Mineta, T.5
Yazaki, T.6
Toda, M.7
Newsome, J.T.8
Platenberg, R.C.9
Manz, H.J.10
Rabkin, S.D.11
-
72
-
-
0034922940
-
Preclinical safety evaluation of G207, a replication-competent herpes simplex virus type 1, inoculated intraprostatically in mice and nonhuman primates
-
Varghese S, Newsome JT, Rabkin SD, McGeagh K, Mahoney D, Nielsen P, Todo T, Martuza RL: Preclinical safety evaluation of G207, a replication-competent herpes simplex virus type 1, inoculated intraprostatically in mice and nonhuman primates. Hum Gene Ther 2001, 12:999-1010
-
(2001)
Hum Gene Ther
, vol.12
, pp. 999-1010
-
-
Varghese, S.1
Newsome, J.T.2
Rabkin, S.D.3
McGeagh, K.4
Mahoney, D.5
Nielsen, P.6
Todo, T.7
Martuza, R.L.8
-
73
-
-
27944459718
-
Unshackling the links between reovirus oncolysis, Ras signaling, translational control and cancer
-
Shmulevitz M, Marcato P, Lee PW: Unshackling the links between reovirus oncolysis, Ras signaling, translational control and cancer. Oncogene 2005, 24:7720-7728
-
(2005)
Oncogene
, vol.24
, pp. 7720-7728
-
-
Shmulevitz, M.1
Marcato, P.2
Lee, P.W.3
-
74
-
-
44349119097
-
Lytic infection with vaccinia virus activates caspases in a Bcl-2-inhibitable manner
-
Kalbacova M, Spisakova M, Liskova J, Melkova Z: Lytic infection with vaccinia virus activates caspases in a Bcl-2-inhibitable manner. Virus Res 2008, 135:53-63
-
(2008)
Virus Res
, vol.135
, pp. 53-63
-
-
Kalbacova, M.1
Spisakova, M.2
Liskova, J.3
Melkova, Z.4
-
75
-
-
33846309244
-
Oncolytic HSV and erlotinib inhibit tumor growth and angiogenesis in a novel malignant peripheral nerve sheath tumor xenograft model
-
Mahller YY, Vaikunth SS, Currier MA, Miller SJ, Ripberger MC, Hsu YH, Mehrian-Shai R, Collins MH, Crombleholme TM, Ratner N, Cripe TP: Oncolytic HSV and erlotinib inhibit tumor growth and angiogenesis in a novel malignant peripheral nerve sheath tumor xenograft model. Mol Ther 2007, 15:279-286
-
(2007)
Mol Ther
, vol.15
, pp. 279-286
-
-
Mahller, Y.Y.1
Vaikunth, S.S.2
Currier, M.A.3
Miller, S.J.4
Ripberger, M.C.5
Hsu, Y.H.6
Mehrian-Shai, R.7
Collins, M.H.8
Crombleholme, T.M.9
Ratner, N.10
Cripe, T.P.11
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