Molecular mechanism of Na+,K+-ATPase malfunction in mutations characteristic of adrenal hypertension

Biochemistry

Volumn 53, Issue 4, 2014, Pages 746-754

  Kopec, Wojciech ^a   Loubet, Bastien ^a   Poulsen, Hanne ^b   Khandelia, Himanshu ^a  

^a UNIVERSITY OF SOUTHERN DENMARK   (Denmark)

^b AARHUS UNIVERSITY   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

ION GRADIENTS; MOLECULAR DYNAMICS SIMULATIONS; MOLECULAR MECHANISM; PHYSIOLOGICAL CONDITION; SODIUM BINDING; STRUCTURAL BEHAVIORS; TRANSMEMBRANE HELICES; WATER-PATHWAY;

ELECTROPHYSIOLOGY; HYDRATION; MOLECULAR DYNAMICS;

IONS;

ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); MUTANT PROTEIN;

ADRENAL GLAND; AMINO ACID SUBSTITUTION; ARTICLE; CONTROLLED STUDY; ELECTROPHYSIOLOGY; ENZYME ACTIVITY; ENZYME MECHANISM; ENZYME STRUCTURE; GAIN OF FUNCTION MUTATION; HYPERTENSION; MOLECULAR DYNAMICS; NONHUMAN; PRIORITY JOURNAL; PROTON TRANSPORT;

ADRENAL GLAND DISEASES; BINDING SITES; CATIONS, MONOVALENT; HUMANS; HYPERTENSION; MOLECULAR DYNAMICS SIMULATION; MUTATION; OUABAIN; PROTEIN BINDING; SODIUM; SODIUM-POTASSIUM-EXCHANGING ATPASE; STATIC ELECTRICITY; WATER;

EID: 84893641602     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi401425g     Document Type: Article

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