Acute ischemic stroke time, penumbra, and reperfusion

Stroke

Volumn 45, Issue 2, 2014, Pages 640-644

  Manning, Nathan W ^a   Campbell, Bruce C V ^a   Oxley, Thomas J ^a   Chapot, René ^b  

^a ROYAL MELBOURNE HOSPITAL   (Australia)

^b ALFRIED KRUPP KRANKENHAUS   (Germany)

Author keywords

Endovascular; Neuroimaging; Reperfusion; Stent retrievers; Stroke; Thrombectomy; Thrombolytic therapy

Indexed keywords

BLOOD CLOT LYSIS; BRAIN ISCHEMIA; BRAIN REGION; ENDOVASCULAR SURGERY; FUNCTIONAL STATUS; NEUROIMAGING; PATIENT SELECTION; PENUMBRA; PRIORITY JOURNAL; RANKIN SCALE; REPERFUSION; REVIEW; TIME;

ENDOVASCULAR; NEUROIMAGING; REPERFUSION; STENT-RETRIEVERS; STROKE; THROMBECTOMY; THROMBOLYTIC THERAPY;

BRAIN ISCHEMIA; ENDOVASCULAR PROCEDURES; HUMANS; NEUROIMAGING; PATIENT SELECTION; REPERFUSION; STROKE;

EID: 84893636559     PISSN: 00392499     EISSN: 15244628     Source Type: Journal    
DOI: 10.1161/STROKEAHA.113.003798     Document Type: Review

References (48)

1. Jauch EC, Saver JL, Adams HP, Bruno A, Connors JJB, Demaerschalk BM, et al. Guidelines for the early management of patients with acute ischemic stroke. Stroke. 2013;44:870-947.
2. Wardlaw JM, Murray V, Berge E, del Zoppo G, Sandercock P, Lindley RL, et al. Recombinant tissue plasminogen activator for acute ischaemic stroke. Lancet. 2012;379:2364-2372.
3. Donnan GA, Davis SM, Parsons MW, Ma H, Dewey HM, Howells DW. How to make better use of thrombolytic therapy in acute ischemic stroke. Nat Rev Neurol. 2011;7:400-409.
4. Astrup J, Siesjö BK, Symon L. Thresholds in cerebral ischemia-the ischemic penumbra. Stroke. 1981;12:723-725.
5. Kaufmann AM, Firlik AD, Fukui MB, Wechsler LR, Jungries CA, Yonas H. Ischemic core and penumbra in human stroke. Stroke. 1999;30:93-99.
6. Albers GW, Thijs VN, Wechsler L, Kemp S, Schlaug G, Skalabrin E, et al. Magnetic resonance imaging profiles predict clinical response to early reperfusion (DEFUSE). Ann Neurol. 2006;60:508-517.
7. Davis SM, Donnan GA, Parsons MW, Levi C, Butcher KS, Peeters A, et al. Effects of alteplase beyond 3 h after stroke in the Echoplanar Imaging Thrombolytic Evaluation Trial (EPITHET). Lancet Neurol. 2008;7:299-309.
8. Lansberg MG, Straka M, Kemp S, Mlynash M, Wechsler LR, Jovin TG, et al. MRI profile and response to endovascular reperfusion after stroke (DEFUSE-2). Lancet Neurol. 2012;11:860-867.
9. Thomalla G, Schwark C, Sobesky J, Bluhmki E, Fiebach JB, Fiehler J, et al. Outcome and symptomatic bleeding complications of intravenous thrombolysis within 6 hours in MRI-selected stroke patients. Stroke. 2006;37:852-858.
10. Köhrmann M, Jüttler E, Fiebach JB, Huttner HB, Siebert S, Schwark C, et al. MRI versus CT-based thrombolysis treatment within and beyond the 3h time window after stroke onset. Lancet Neurol. 2006;5:661-667.
11. Parsons M, Spratt N, Bivard A, Campbell B, Chung K, Miteff F, et al. A randomized trial of tenecteplase versus alteplase for acute ischemic stroke. N Engl J Med. 2012;366:1099-1107.
12. Campbell BCV, Christensen S, Butcher KS, Gordon I, Parsons MW, Desmond PM, et al. Regional very low cerebral blood volume predicts hemorrhagic transformation better than DWI volume and thresholded ADC in acute ischemic stroke. Stroke. 2010;41:82-88.
13. Porelli S, Leonardi M, Stafa A, Barbara C, Procaccianti G, Simonetti L. CT angiography in an acute stroke protocol: correlation between occlusion site and outcome of intravenous thrombolysis. Interv Neuroradiol. 2013;19:87-96.
14. González RG, Furie KL, Goldmacher GV, Smith WS, Kamalian S, Payabvash S, et al. Good outcome rate of 35% in IV-tPA-treated patients with computed tomography angiography confirmed severe anterior circulation occlusive stroke. Stroke. 2013;44:3109-3113.
15. Straka M, Albers GW, Bammer R. Real-time diffusion- perfusion mismatch analysis in acute stroke. J Magn Reson Imaging. 2010;32:1024-1037.
16. Turk A, Magarik JA, Chaudry I, Turner RD, Nicholas J, Holmstedt CA, et al. CT perfusion-guided patient selection for endovascular treatment of acute ischemic stroke is safe and effective. J Neurointerv Surg. 2012;4:261-265.
17. Kidwell CS, Jahan R, Gornbein J, Alger JR, Nenov V, Ajani Z, et al; MR RESCUE Investigators. A trial of imaging selection and endovascular treatment for ischemic stroke. N Engl J Med. 2013;368:914-923.
18. Wheeler HM, Mlynash M, Inoue M, Tipirneni A, Liggins J, Zaharchuk G, et al. Early DWI and perfusion-weighted imaging lesion volumes forecast final infarct size in DEFUSE-2. Stroke. 2013;44:681-685.
19. Lansberg MG, Lee J, Christensen S, Straka M, De Silva DA, Mlynash M, et al. RAPID automated patient selection for reperfusion therapy. Stroke. 2011;42:1608-1614.
20. Kidwell CS, Wintermark M, De Silva DA, Schaewe TJ, Jahan R, Starkman S, et al. Multiparametric MRI and CT models of infarct core and favorable penumbral imaging patterns in acute ischemic stroke. Stroke. 2013;44:73-79.
21. Lev MH, Segal AZ, Farkas J, Hossain ST, Putman C, Hunter GJ, et al. Utility of perfusion-weighted CT imaging in acute middle cerebral artery stroke treated with intra-arterial thrombolysis. Stroke. 2001;32:2021-2028.
22. Yoo AJ, Verduzco LA, Schaefer PW, Hirsch JA, Rabinov JD, Gonzalez RG. MRI-based selection for intra-arterial stroke therapy. Stroke. 2009;40:2046-2054.
23. Parsons MW, Christensen S, McElduff P, Levi CR, Butcher KS, De Silva DA, et al. Pretreatment diffusion-and perfusion-MR lesion volumes have a crucial influence on clinical response to stroke thrombolysis. J Cereb Blood Flow Metab. 2010;30:1214-1225.
24. Campbell BCV, Mitchell PJ, Yan B, Parsons MW, Christensen S, Churilov L, et al. A multicenter, randomized, controlled study to investigate EXtending the time for Thrombolysis in Emergency Neurological Deficits with Intra-Arterial therapy (EXTEND-IA). Int J Stroke. November 10, 2013. doi: 10.1111/ijs.12206.: http://onlinelibrary.wiley. com/doi/10.1111/ijs.12206/abstract. Accessed November 10, 2013.
25. De Silva DA, Fink JN, Christensen S, Ebinger M, Bladin C, Levi CR, et al; Echoplanar Imaging Thrombolytic Evaluation Trial (EPITHET) Investigators. Assessing reperfusion and recanalization as markers of clinical outcomes after intravenous thrombolysis in the echoplanar imaging thrombolytic evaluation trial (EPITHET). Stroke. 2009;40:2872-2874.
26. Soares BP, Chien JD, Wintermark M. MR and CT monitoring of recanalization, reperfusion, and penumbra salvage. Stroke. 2009;40:S24-S27.
27. Soares BP, Tong E, Hom J, Cheng S-C, Bredno J, Boussel L, et al. Reperfusion is a more accurate predictor of follow-up infarct volume than recanalization. Stroke. 2010;41:e34-e40.
28. Dávalos A, Pereira VM, Chapot R, Bonafé A, Andersson T, Gralla J; Solitaire Group. Retrospective multicenter study of Solitaire FR for revascularization in the treatment of acute ischemic stroke. Stroke. 2012;43:2699-2705.
29. Pereira VM, Gralla J, Davalos A, Bonafé A, Castaño C, Chapot R, et al. Prospective, multicenter, single-arm study of mechanical thrombectomy using Solitaire Flow Restoration in acute ischemic stroke. Stroke. 2013;44:2802-2807.
30. Furlan A, Higashida R, Wechsler L, Gent M, Rowley H, Kase C, et al. Intra-arterial prourokinase for acute ischemic stroke. The PROACT II study. JAMA. 1999;282:2003-2011.
31. NINDS tPA Stroke Study Group. Tissue plasminogen activator for acute ischemic stroke. N Engl J Med. 1995;333:1581-1587.
32. Ciccone A, Valvassori L, Nichelatti M, Sgoifo A, Ponzio M, Sterzi R, et al; SYNTHESIS Expansion Investigators. Endovascular treatment for acute ischemic stroke. N Engl J Med. 2013;368:904-913.
33. Ciccone A, Valvassori L, Ponzio M, Ballabio E, Gasparotti R, Sessa M, et al; SYNTHESIS Investigators. Intra-arterial or intravenous thrombolysis for acute ischemic stroke? The SYNTHESIS pilot trial. J Neurointerv Surg. 2010;2:74-79.
34. Broderick JP, Palesch YY, Demchuk AM, Yeatts SD, Khatri P, Hill MD, et al; Interventional Management of Stroke (IMS) III Investigators. Endovascular therapy after intravenous t-PA versus t-PA alone for stroke. N Engl J Med. 2013;368:893-903.
35. Lees KR, Bluhmki E, Kummer von R, Brott TG, Toni D, Grotta JC, et al. Time to treatment with intravenous alteplase and outcome in stroke. Lancet. 2010;375:1695-703.
36. Khatri P, Abruzzo T, Yeatts SD, Nichols C, Broderick JP, Tomsick TA; IMS I and II Investigators. Good clinical outcome after ischemic stroke with successful revascularization is time-dependent. Neurology. 2009;73:1066-1072.
37. Tomsick T, Broderick J, Carrozella J, Khatri P, Hill M, Palesch Y, et al; Interventional Management of Stroke II Investigators. Revascularization results in the Interventional Management of Stroke II trial. Am J Neuroradiol. 2008;29:582-587.
38. Koh JS, Lee SJ, Ryu CW, Kim HS. Safety and efficacy of mechanical thrombectomy with solitaire stent retrieval for acute ischemic stroke: a systematic review. Neurointervention. 2012;7:1-9.
39. Jayaraman MV, Grossberg JA, Meisel KM, Shaikhouni A, Silver B. The clinical and radiographic importance of distinguishing partial from near-complete reperfusion following intra-arterial stroke therapy. Am J Neuroradiol. 2013;34:135-139.
40. Yoo AJ, Simonsen CZ, Prabhakaran S, Chaudhry ZA, Issa MA, Fugate JE, et al. Refining angiographic biomarkers of revascularization. Stroke. 2013;44:2509-2512.
41. Zaidat OO, Yoo AJ, Khatri P, Tomsick TA, Kummer von R, Saver JL, et al. Recommendations on angiographic revascularization grading standards for acute ischemic stroke. Stroke. 2013;44:2650-2663.
42. Todo A, Minaeian A, Sahni R, Chao KH. Incidence and outcome of procedural distal emboli using the Penumbra thrombectomy for acute stroke. J Neurointerv Surg. 2013;5:135-138.
43. Saver JL, Jahan R, Levy EI, Jovin TG, Baxter B, Nogueira RG, et al. Solitaire flow restoration device versus the Merci Retriever in patients with acute ischaemic stroke (SWIFT). Lancet. 2012;380:1241-1249.
44. Almekhlafi MA, Menon BK, Freiheit EA, Demchuk AM, Goyal M. A meta-analysis of observational intra-arterial stroke therapy studies using the Merci device, Penumbra system, and retrievable stents. Am J Neuroradiol. 2013;34:140-145.
45. Brekenfeld C, Schroth G, Mordasini P, Fischer U, Mono ML, Weck A, et al. Impact of retrievable stents on acute ischemic stroke treatment. Am J Neuroradiol. 2011;32:1269-1273.
46. Ribo M, Molina CA, Jankowitz B, Tomasello A, Zaidi S, Jumaa M, et al. Stentrievers versus other endovascular treatment methods for acute stroke. J Neurointerv Surg. May 28, 2013. doi:10.1136/neurintsurg- 2013-010748. Accessed July 23, 2013.
47. Meretoja A, Strbian D, Mustanoja S, Tatlisumak T, Lindsberg PJ, Kaste M. Reducing in-hospital delay to 20 minutes in stroke thrombolysis. Neurology. 2012;79:306-313.
48. Meretoja A, Weir L, Ugalde M, Yassi N, Yan B, Hand P, et al. Helsinki model cut stroke thrombolysis delays to 25 minutes in Melbourne in only 4 months. Neurology. 2013;81:1071-1076.