Dichloroacetate at therapeutic concentration alters glucose metabolism and induces regulatory t-cell differentiation in alloreactive human lymphocytes

Journal of Basic and Clinical Physiology and Pharmacology

Volumn 24, Issue 4, 2013, Pages 271-276

  Eleftheriadis, Theodoros ^a   Pissas, Georgios ^a   Karioti, Aggeliki ^a   Antoniadi, Georgia ^a   Antoniadis, Nikolaos ^a,b   Liakopoulos, Vassilios ^a   Stefanidis, Ioannis ^a  

^a UNIVERSITY OF THESSALY   (Greece)

^b ARISTOTLE UNIVERSITY OF THESSALONIKI   (Greece)

Author keywords

Aerobic glycolysis; Autoimmunity; Cancer; Dichloroacetate; FOXP3; Interleukin 10; Regulatory T cells; Transplantation

Indexed keywords

DICHLOROACETIC ACID; GLUCOSE; INTERLEUKIN 10; LACTATE DEHYDROGENASE; LACTIC ACID; TRANSCRIPTION FACTOR FOXP3;

ADULT; ALLOIMMUNITY; ARTICLE; CELL LYSATE; CELL MEDIATED CYTOTOXICITY; CLINICAL ARTICLE; CYTOKINE PRODUCTION; CYTOTOXICITY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; GLUCOSE METABOLISM; GLUCOSE TRANSPORT; GLYCOLYSIS; HUMAN; HUMAN CELL; LYMPHOCYTE DIFFERENTIATION; LYMPHOCYTE PROLIFERATION; MALE; MIXED LYMPHOCYTE REACTION; NORMAL HUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; PROTEIN EXPRESSION; REGULATORY T LYMPHOCYTE; SUPERNATANT;

AEROBIOSIS; AUTOIMMUNITY; CELL CULTURE TECHNIQUES; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL SURVIVAL; CELLS, CULTURED; DICHLOROACETIC ACID; DOSE-RESPONSE RELATIONSHIP, DRUG; FORKHEAD TRANSCRIPTION FACTORS; GLUCOSE; GLYCOLYSIS; HUMANS; INTERLEUKIN-10; LEUKOCYTES, MONONUCLEAR; T-LYMPHOCYTES, REGULATORY;

EID: 84893569114     PISSN: 07926855     EISSN: 21910286     Source Type: Journal    
DOI: 10.1515/jbcpp-2013-0001     Document Type: Article

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