Molecular dynamics analysis of a novel β3 Pro189Ser mutation in a patient with Glanzmann thrombasthenia differentially affecting αIIbβ3 and αvβ3 expression

PLoS ONE

Volumn 8, Issue 11, 2013, Pages

  Laguerre, Michel ^a   Sabi, Essa ^b   Daly, Martina ^b   Stockley, Jacqueline ^b   Nurden, Paquita ^c,d   Pillois, Xavier ^e   Nurden, Alan T ^c  

^a INSTITUT EUROPÉEN DE CHIMIE ET BIOLOGIE   (France)

^b UNIVERSITY OF SHEFFIELD   (United Kingdom)

^c Ctr Geriatrie Ctr Hosp Univ B   (France)

^d TIMONE HOSPITAL   (France)

^e HAUT LÉVÊQUE HOSPITAL   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMALS; CHO CELLS; CRICETINAE; CRICETULUS; FEMALE; GENE EXPRESSION; HUMANS; HYDROGEN BONDING; INTEGRIN ALPHA2; INTEGRIN ALPHAV; INTEGRIN BETA3; MIDDLE AGED; MOLECULAR DYNAMICS SIMULATION; MUTATION, MISSENSE; PROTEIN INTERACTION DOMAINS AND MOTIFS; PROTEIN STRUCTURE, QUATERNARY; PROTEIN STRUCTURE, SECONDARY; THROMBASTHENIA;

EID: 84893567862     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0078683     Document Type: Article

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