In vivo delivery of Atoh1 gene to rat cochlea using a dendrimer-based nanocarrier

Journal of Biomedical Nanotechnology

Volumn 9, Issue 10, 2013, Pages 1736-1745

  Wu, Nan ^a   Li, Min ^b   Chen, Zhi Ting ^a   Zhang, Xiao Bing ^c   Liu, Hui Zhan ^a   Li, Zhou ^d   Guo, Wei Wei ^a   Zhao, Li Dong ^a   Ren, Li Li ^a   Li, Jia Nan ^a   Yi, Hai Jin ^a   Han, Dong ^b   Yang, Wei Yan ^a   Wu, Yan ^b   Yang, Shi Ming ^a  

^a CHINESE PLA GENERAL HOSPITAL   (China)

^b NATIONAL CENTER FOR NANOSCIENCE AND TECHNOLOGY   (China)

^c LANZHOU UNIVERSITY   (China)

^d BEIHANG UNIVERSITY   (China)

Author keywords

Activation; Cochlea; Gene delivery; Hearing loss; Na carboxymethyl cyclodextrin modification; PAMAM dendrimers

Indexed keywords

AUDITION; BIOLOGICAL MATERIALS; CHEMICAL ACTIVATION; CYCLODEXTRINS; DENDRIMERS; GENE TRANSFER; GENES; PARTICLE SIZE; RATS; SODIUM;

CARBOXYMETHYL; COCHLEA; GENE DELIVERY; HEARING LOSS; PAMAM DENDRIMER;

GENE THERAPY;

ATONAL HOMOLOG 1; BASIC HELIX LOOP HELIX TRANSCRIPTION FACTOR; BETA CYCLODEXTRIN; EPIDERMAL GROWTH FACTOR RECEPTOR; NANOCARRIER; POLYAMIDOAMINE; SODIUM CARBOXYMETHYL BETA CYCLODEXTRIN; UNCLASSIFIED DRUG; ATOH1 PROTEIN, RAT; DENDRIMER; DNA; NANOCAPSULE; PAMAM STARBURST;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELLS BY BODY ANATOMY; COCHLEA; COCHLEA FENESTRA; CONTROLLED STUDY; DNA DRUG COMPLEX; EVOKED BRAIN STEM AUDITORY RESPONSE; FLUORESCENCE; GENE; GENE CONSTRUCT; HAIR CELL; IN VIVO GENE TRANSFER; INNER EAR; INOCULATION; MALE; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; PARTICLE SIZE; PLASMID; RAT; SEQUENCE ANALYSIS; ZETA POTENTIAL; ANIMAL; CHEMISTRY; GENETIC TRANSFECTION; GENETICS; MATERIALS TESTING; PHYSIOLOGY; PROCEDURES; SPRAGUE DAWLEY RAT; ULTRASTRUCTURE;

ANIMALS; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; COCHLEA; DENDRIMERS; DNA; MALE; MATERIALS TESTING; NANOCAPSULES; PARTICLE SIZE; RATS; RATS, SPRAGUE-DAWLEY; TRANSFECTION;

EID: 84893563627     PISSN: 15507033     EISSN: 15507041     Source Type: Journal    
DOI: 10.1166/jbn.2013.1684     Document Type: Article

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