Effect of platelet lysate on human cells involved in different phases of wound healing

PLoS ONE

Volumn 8, Issue 12, 2013, Pages

  Barsotti, Maria Chiara ^a   Losi, Paola ^b   Briganti, Enrica ^b   Sanguinetti, Elena ^b   Magera, Angela ^c   Al Kayal, Tamer ^b   Feriani, Roberto ^a   Di Stefano, Rossella ^a   Soldani, Giorgio ^b  

^a UNIVERSITY OF PISA   (Italy)

^b INSTITUTE OF CLINICAL PHYSIOLOGY   (Italy)

^c Kedrion SpA Loc Ai Conti   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MAPK1 PROTEIN, HUMAN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3;

CELL LINE; CELL PROLIFERATION; CELL SURVIVAL; CHEMISTRY; CYTOLOGY; HUMAN; METABOLISM; SIGNAL TRANSDUCTION; THROMBOCYTE; UMBILICAL VEIN ENDOTHELIAL CELL; WOUND HEALING;

BLOOD PLATELETS; CELL LINE; CELL PROLIFERATION; CELL SURVIVAL; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; MAP KINASE SIGNALING SYSTEM; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; NF-KAPPA B; WOUND HEALING;

EID: 84893528923     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0084753     Document Type: Article

References (40)

1. Dulmovits BM, Herman IM (2012) Microvascular remodeling and wound healing: a role for pericytes. Int J Biochem Cell Biol 44: 1800-1812. doi:10.1016/j.biocel.2012.06.031. PubMed: 22750474.
2. Anitua E, Sánchez M, Nurden AT, Nurden P, Orive G et al. (2006) New insights into and novel applications for platelet-rich fibrin therapies. Trends Biotechnol 24: 227-234. doi:10.1016/j.tibtech.2006.02.010. PubMed: 16540193.
3. Nurden AT (2011) Platelets, inflammation and tissue regeneration. Thromb Haemost 105 Suppl 1: S13-S33. doi:10.1160/THS10-11-0720. PubMed: 21479340.
4. Radziwon-Balicka A, Moncada de la Rosa C, Jurasz P (2012) Platelet-associated angiogenesis regulating factors: a pharmacological perspective. Can J Physiol Pharmacol 90: 679-688. doi:10.1139/y2012-036. PubMed: 22512504.
5. Ranzato E, Patrone M, Mazzucco L, Burlando B (2008) Platelet lysate stimulates wound repair of HaCaT keratinocytes. Br J Dermatol 159: 537-545. PubMed: 18616790.
6. Mazzucco L, Medici D, Serra M, Panizza R, Rivara G et al. (2004) The use of autologous platelet gel to treat difficult-to-heal wounds: a pilot study. Transfusion 44: 1013-1018. doi:10.1111/j.1537-2995.2004.03366.x. PubMed: 15225241. (Pubitemid 38823807)
7. Borzini P, Mazzucco L (2005) Tissue regeneration and in loco administration of platelet derivatives: clinical outcome, heterogeneous products, and heterogeneity of the effector mechanisms. Transfusion 45: 1759-1767. doi:10.1111/j.1537-2995.2005.00600.x. PubMed: 16271101. (Pubitemid 43923903)
8. Pawitan JA (2012) Platelet rich plasma in xeno-free stem cell culture: the impact of platelet count and processing method. Curr Stem Cell Res Ther 7: 329-335. doi:10.2174/157488812802481508. PubMed: 22849700.
9. Reinisch A, Bartmann C, Rohde E, Schallmoser K, Bjelic-Radisic V et al. (2007) Humanized system to propagate cord blood-derived multipotent mesenchymal stromal cells for clinical application. Regen Med 2: 371-382. doi:10.2217/17460751.2.4.371. PubMed: 17635045. (Pubitemid 47304957)
10. Bernardi M, Albiero E, Alghisi A, Chieregato K, Lievore C et al. (2013) Production of human platelet lysate by use of ultrasound for ex vivo expansion of human bone marrow-derived mesenchymal stromal cells. Cytotherapy 15: 920-929. doi:10.1016/j.jcyt.2013.01.219. PubMed: 23623274.
11. Felice F, Lucchesi D, di Stefano R, Barsotti MC, Storti E et al. (2010) Oxidative stress in response to high glucose levels in endothelial cells and in endothelial progenitor cells Evidence for differential glutathione peroxidase-1 expression. Microvasc Res 80: 332-338. doi:10.1016/j.mvr.2010.05.004. PubMed: 20471990.
12. Ranzato E, Mazzucco L, Patrone M, Burlando B (2009) Platelet lysate promotes in vitro wound scratch closure of human dermal fibroblasts: different roles of cell calcium, P38, ERK and PI3K/AKT. J Cell Mol Med 13: 2030-2038. doi:10.1111/j.1582-4934.2008.00467.x. PubMed: 19267882.
13. Da Pozzo E, Barsotti MC, Bendinelli S, Martelli A, Calderone V et al. (2012) Differential Effects of Fondaparinux and Bemiparin on Angiogenic and Vasculogenesis-like processes. Thromb Res 130: e113-e122. doi:10.1016/j. thromres.2012.03.013. PubMed: 22497885.
14. Papanas N, Eleftheriadou I, Tentolouris N, Maltezos E (2012) Advances in the topical treatment of diabetic foot ulcers. Curr Diabetes Rev 8: 209-218. doi:10.2174/157339912800563963. PubMed: 22429013.
15. Occleston NL, O'Kane S, Laverty HG, Cooper M, Fairlamb D et al. (2011) Discovery and development of avotermin (recombinant human transforming growth factor beta 3): a new class of prophylactic therapeutic for the improvement of scarring. Wound Repair Regen 19 Suppl 1: s38-s48. doi:10.1111/j.1524-475X.2011. 00711.x. PubMed: 21793965.
16. Doucet C, Ernou I, Zhang Y, Llense JR, Begot L et al. (2005) Platelet lysates promote mesenchymal stem cell expansion: a safety substitute for animal serum in cell-based therapy applications. J Cell Physiol 205: 228-236. doi:10.1002/jcp.20391. PubMed: 15887229. (Pubitemid 41428905)
17. Mazzucco L, Balbo V, Guaschino R (2012) "Reasonable compromise" to define the quality standards of platelet concentrate for non-transfusion use (CPunT). Transfus Apher Sci 47: 207-211. doi:10.1016/j.transci.2012.06.006. PubMed: 22795794.
18. Jonsdottir-Buch SM, Lieder R, Sigurjonsson OE (2013) Platelet lysates produced from expired platelet concentrates support growth and osteogenic differentiation of mesenchymal stem cells. PLOS ONE 8: e68984. doi:10.1371/journal.pone.0068984. PubMed: 23874839.
19. Novosel EC, Kleinhans C, Kluger PJ (2011) Vascularization is the key challenge in tissue engineering. Adv Drug Deliv Rev 63: 300-311. doi:10.1016/j.addr.2011.03.004. PubMed: 21396416.
20. Yang DH, Hsu CF, Lin CY, Guo JY, Yu WC et al. (2013) Krüppel-like factor 10 upregulates the expression of cyclooxygenase 1 and further modulates angiogenesis in endothelial cell and platelet aggregation in gene-deficient mice. Int J Biochem Cell Biol 45: 419-428. doi:10.1016/j.biocel.2012.11.007. PubMed: 23178857.
21. Kajdaniuk D, Marek B, Foltyn W, Kos-Kudła B (2011) Vascular endothelial growth factor (VEGF) - part 1: in physiology and pathophysiology. Endokrynol Pol 62: 444-455. PubMed: 22069106.
22. Fekete N, Gadelorge M, Fürst D, Maurer C, Dausend J et al. (2012) Platelet lysate from whole blood-derived pooled platelet concentrates and apheresis-derived platelet concentrates for the isolation and expansion of human bone marrow mesenchymal stromal cells: production process, content and identification of active components. Cytotherapy 14: 540-554. doi:10.3109/14653249.2012.655420. PubMed: 22296115.
23. Ranzato E, Boccafoschi F, Mazzucco L, Patrone M, Burlando B (2010) Role of ERK1/2 in platelet lysate-driven endothelial cell repair. J Cell Biochem 110: 783-793. doi:10.1002/jcb.22591. PubMed: 20512938.
24. Radziwon-Balicka A, Moncada de la Rosa C, Zielnik B, Doroszko A, Jurasz P (2013) Temporal and pharmacological characterization of angiostatin release and generation by human platelets: implications for endothelial cell migration. PLOS ONE 8: e59281. doi:10.1371/journal.pone.0059281. PubMed: 23555012.
25. Sum R, Hager S, Pietramaggiori G, Orgill DP, Dee J et al. (2007) Wound-healing properties of trehalose-stabilized freeze-dried outdated platelets. Transfusion 47: 672-679. doi:10.1111/j.1537-2995.2007.01170.x. PubMed: 17381626. (Pubitemid 46449628)
26. Battinelli EM, Markens BA, Italiano JE (2011) Release of angiogenesis regulatory proteins from platelet alpha granules: modulation of physiologic and pathologic angiogenesis. Blood 118: 1359-1369. doi:10.1182/blood-2011-02-334524. PubMed: 21680800.
27. Moncada de la Rosa C, Radziwon-Balicka A, El-Sikhry H, Seubert J, Ruvolo PP et al. (2013) Pharmacologic protein kinase Cα inhibition uncouples human platelet-stimulated angiogenesis from collagen-induced aggregation. J Pharmacol Exp Ther 345: 15-24. doi:10.1124/jpet.112.200881. PubMed: 23386249.
28. El Backly R, Ulivi V, Tonachini L, Cancedda R, Descalzi F et al. (2011) Platelet lysate induces in vitro wound healing of human keratinocytes associated with a strong proinflammatory response. Tissue Eng Part A 17: 1787-1800. doi:10.1089/ten.tea.2010.0729. PubMed: 21385008.
29. Burnouf T, Chou ML, Wu YW, Su CY, Lee LW (2013) Antimicrobial activity of platelet (PLT)-poor plasma, PLT-rich plasma, PLT gel, and solvent/detergent- treated PLT lysate biomaterials against wound bacteria. Transfusion 53: 138-146. doi:10.1111/j.1537-2995.2012.03668.x. PubMed: 22563709.
30. Roskoski R (2012) ERK1/2 MAP kinases: structure, function, and regulation. Pharmacol Res 66: 105-143. doi:10.1016/j.phrs.2012.04.005. PubMed: 22569528.
31. Lee SH, Zahoor M, Hwang JK, Min, Choi KY (2012) Valproic acid induces cutaneous wound healing in vivo and enhances keratinocyte motility. PLOS ONE 7: e48791. doi:10.1371/journal.pone.0048791. PubMed: 23144972.
32. Watson A, Morris VL, Chan BM (2009) Coordinated integrin and growth factor regulation of primary keratinocyte migration mediated through extracellular signal regulated kinase and phosphoinositide 3-kinase. Arch Dermatol Res 301: 307-317. doi:10.1007/s00403-009-0945-7. PubMed: 19330341.
33. Lan W, Petznick A, Heryati S, Rifada M, Tong L (2012) Nuclear Factor-κB: central regulator in ocular surface inflammation and diseases. Ocul Surf 10: 137-148. doi:10.1016/j.jtos.2012.04.001. PubMed: 22814642.
34. Melchionna R, Bellavia G, Romani M, Straino S, Germani A et al. (2012) C/EBPγ regulates wound repair and EGF receptor signaling. J Invest Dermatol 132: 1908-1917. doi:10.1038/jid.2012.51. PubMed: 22437320.
35. Valacchi G, Pecorelli A, Sticozzi C, Torricelli C, Muscettola M et al. (2011) Rottlerin exhibits antiangiogenic effects in vitro. Chem Biol Drug Des 77: 460-470. doi:10.1111/j.1747-0285.2011.01121.x. PubMed: 21435184.
36. Kim YW, West XZ, Byzova TV (2013) Inflammation and oxidative stress in angiogenesis and vascular disease. J Mol Med (Berl) 91: 323-328. doi:10.1007/s00109-013-1007-3. PubMed: 23430240.
37. Ranzato E, Martinotti S, Volante A, Mazzucco L, Burlando B (2011) Platelet lysate modulates MMP-2 and MMP-9 expression, matrix deposition and cell-to-matrix adhesion in keratinocytes and fibroblasts. Exp Dermatol 20: 308-313. doi:10.1111/j.1600-0625.2010.01173.x. PubMed: 20955204.
38. Losi P, Briganti E, Errico C, Lisella A, Sanguinetti E et al. (2013) Fibrin-based scaffold incorporating VEGF- and bFGF-loaded nanoparticles stimulates wound healing in diabetic mice. Acta Biomater 9: 7814-7821. doi:10.1016/j.actbio.2013.04.019. PubMed: 23603001.
39. Ito R, Morimoto N, Pham LH, Taira T, Kawai K et al. (2013) Efficacy of the controlled release of concentrated platelet lysate from a collagen/gelatin scaffold for dermis-like tissue regeneration. Tissue Eng Part A 19: 1398-1405. doi:10.1089/ten.tea.2012.0375. PubMed: 23427847.
40. Rossi S, Faccendini A, Bonferoni MC, Ferrari F, Sandri G et al. (2013) "Sponge-like" dressings based on biopolymers for the delivery of platelet lysate to skin chronic wounds. Int J Pharm 440: 207-215. doi:10.1016/j.ijpharm.2012.07.056. PubMed: 22884830.