Oxidative stress in response to high glucose levels in endothelial cells and in endothelial progenitor cells. Evidence for differential glutathione peroxidase-1 expression.

Microvascular Research

Volumn 80, Issue 3, 2010, Pages 332-338

  Felice, Francesca ^a   Lucchesi, Daniela ^a   di Stefano, Rossella ^a   Barsotti, Maria Chiara ^a   Storti, Eugenia ^a   Penno, Giuseppe ^a   Balbarini, Alberto ^a   Del Prato, Stefano ^a   Pucci, Laura ^a  

^a UNIVERSITY OF PISA   (Italy)

Author keywords

Antioxidative enzyme; Endothelial progenitor cells; HUVECs; Hyperglycaemia; Reactive oxygen species

Indexed keywords

GLUCOSE; GLUTATHIONE PEROXIDASE 1; REACTIVE OXYGEN METABOLITE;

ARTICLE; CELL GROWTH; CELL STRAIN; CELL STRESS; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME ACTIVATION; ENZYME ACTIVITY; HUMAN; HUMAN CELL; HUMAN UMBILICAL VEIN ENDOTHELIAL CELL; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; STEM CELL;

ADULT; BIOLOGICAL MARKERS; CELL SURVIVAL; CELLS, CULTURED; ENDOTHELIAL CELLS; GENE EXPRESSION REGULATION, NEOPLASTIC; GLUCOSE; GLUTATHIONE PEROXIDASE; HUMANS; HYPERGLYCEMIA; MALE; OXIDATIVE STRESS; PHENOTYPE; REACTIVE OXYGEN SPECIES; STEM CELLS; TIME FACTORS; UP-REGULATION;

EID: 78249286483     PISSN: 00262862     EISSN: 10959319     Source Type: Journal    
DOI: 10.1016/j.mvr.2010.05.004     Document Type: Article

References (37)

1. Annuk M., Zilmer M., Fellstrom B. Endothelium-dependent vasodilation and oxidative stress in chronic renal failure: impact on cardiovascular disease. Kidney Int. 2003, S50-S53. Suppl.
2. Asahara T., Murohara T., Sullivan A., Silver M., van der Zee R., Li T., Witzenbichler B., Schatteman G., Isner J.M. Isolation of putative progenitor endothelial cells for angiogenesis. Science 1997, 275:964-967.
3. Assmus B., Schachinger V., Teupe C., Britten M., Lehmann R., Dobert N., Grunwald F., Aicher A., Urbich C., Martin H., Hoelzer D., Dimmeler S., Zeiher A.M. Transplantation of progenitor cells and regeneration enhancement in acute myocardial infarction (TOPCARE-AMI). Circulation 2002, 106:3009-3017.
4. Balbarini A., Barsotti M.C., Di Stefano R., Leone A., Santoni T. Circulating endothelial progenitor cells characterization, function and relationship with cardiovascular risk factors. Curr. Pharm. Des. 2007, 13:1699-1713.
5. Bonomini F., Tengattini S., Fabiano A., Bianchi R., Rezzani R. Atherosclerosis and oxidative stress. Histol. Histopathol. 2008, 23:381-390.
6. Cai H., Harrison D.G. Endothelial dysfunction in cardiovascular diseases: the role of oxidant stress. Circ. Res. 2000, 87:840-844.
7. Callaghan M.J., Ceradini D.J., Gurtner G.C. Hyperglycemia-induced reactive oxygen species and impaired endothelial progenitor cell function. Antioxid. Redox Signal. 2005, 7:1476-1482.
8. Dernbach E., Urbich C., Brandes R.P., Hofmann W.K., Zeiher A.M., Dimmeler S. Antioxidative stress-associated genes in circulating progenitor cells: evidence for enhanced resistance against oxidative stress. Blood 2004, 104:3591-3597.
9. Di Stefano R., Santoni T., Barsotti M.C., Armani C., Chifenti B., Guida C., Vanacore R., Locci M.T., Mariani M., Balbarini A., Mariani M. Different growth conditions for peripheral blood endothelial progenitors. Cardiovasc. Radiat. Med. 2002, 3:172-175.
10. Fadini G.P., Pucci L., Vanacore R., Baesso I., Penno G., Balbarini A., Di Stefano R., Miccoli R., de Kreutzenberg S., Coracina A., Tiengo A., Agostini C., Del Prato S., Avogaro A. Glucose tolerance is negatively associated with circulating progenitor cell levels. Diabetologia 2007, 50:2156-2163.
11. Fuchs S., Hermanns M.I., Kirkpatrick C.J. Retention of a differentiated endothelial phenotype by outgrowth endothelial cells isolated from human peripheral blood and expanded in long-term cultures. Cell Tissue Res. 2006, 326:79-92.
12. Galasso G., Schiekofer S., Sato K., Shibata R., Handy D.E., Ouchi N., Leopold J.A., Loscalzo J., Walsh K. Impaired angiogenesis in glutathione peroxidase-1-deficient mice is associated with endothelial progenitor cell dysfunction. Circ. Res. 2006, 98:254-261.
13. He T., Peterson T.E., Holmuhamedov E.L., Terzic A., Caplice N.M., Oberley L.W., Katusic Z.S. Human endothelial progenitor cells tolerate oxidative stress due to intrinsically high expression of manganese superoxide dismutase. Arterioscler. Thromb. Vasc. Biol. 2004, 24:2021-2027.
14. He T., Smith L.A., Harrington S., Nath K.A., Caplice N.M., Katusic Z.S. Transplantation of circulating endothelial progenitor cells restores endothelial function of denuded rabbit carotid arteries. Stroke 2004, 35:2378-2384.
15. He T., Joyner M.J., Katusic Z.S. Aging decreases expression and activity of glutathione peroxidase-1 in human endothelial progenitor cells. Microvasc. Res. 2009, 78(3):447-452.
16. Hill J.M., Zalos G., Halcox J.P., Schenke W.H., Waclawiw M.A., Quyyumi A.A., Finkel T. Circulating endothelial progenitor cells, vascular function, and cardiovascular risk. N. Engl. J. Med. 2003, 348:593-600.
17. Hirschi K.K., Ingram D.A., Yoder M.C. Assessing identity, phenotype, and fate of endothelial progenitor cells. Arterioscler. Thromb. Vasc. Biol. 2008, 28:1584-1595.
18. Hur J., Yoon C.H., Kim H.S., Choi J.H., Kang H.J., Hwang K.K., Oh B.H., Lee M.M., Park Y.B. Characterization of two types of endothelial progenitor cells and their different contributions to neovasculogenesis. Arterioscler. Thromb. Vasc. Biol. 2004, 24:288-293.
19. Ivanova N.B., Dimos J.T., Schaniel C., Hackney J.A., Moore K.A., Lemischka I.R. A stem cell molecular signature. Science 2002, 298:601-604.
20. Lapenna D., de Gioia S., Ciofani G., Mezzetti A., Ucchino S., Calafiore A.M., Napolitano A.M., Di Ilio C., Cuccurullo F. Glutathione-related antioxidant defenses in human atherosclerotic plaques. Circulation 1998, 97:1930-1934.
21. Lin Y., Weisdorf D.J., Solovey A., Hebbel R.P. Origins of circulating endothelial cells and endothelial outgrowth from blood. J. Clin. Invest. 2000, 105:71-77.
22. Miller S., Walker S.W., Arthur J.R., Nicol F., Pickard K., Lewin M.H., Howie A.F., Beckett G.J. Clin. Sci. 2001, 100:543-550.
23. Morais C., Westhuyzen J., Pat B., Gobe G., Healy H. High ambient glucose is effect neutral on cell death and proliferation in human proximal tubular epithelial cells. Am. J. Physiol. Renal. Physiol. 2005, 289:F401-F409.
24. Muller F.L., Lustgarten M.S., Jang Y., Richardson A., Van Remmen H. Trends in oxidative aging theories. Free Radic. Biol. Med. 2007, 43(4):477-503.
25. Murphy M.P. How mitochondria produce reactive oxygen species. Biochem. J. 2009, 417:1-13.
26. Nishikawa T., Kukidome D., Sonoda K., Fujisawa K., Matsuhisa T., Motoshima H., Matsumura T., Araki E. Impact of mitochondrial ROS production on diabetic vascular complications. Diab. Res. Clin. Pract. 2007, 77(Suppl 1):S41-S45.
27. Raes M., Michiels C., Remacle J. Comparative study of the enzymatic defense systems against oxygen-derived free radicals: the key role of glutathione peroxidase. Free Radic. Biol. Med. 1987, 3:3-7.
28. Ramalho-Santos M., Yoon S., Matsuzaki Y., Mulligan R.C., Melton D.A. "Stemness": transcriptional profiling of embryonic and adult stem cells. Science 2002, 298:597-600.
29. Recchioni R., Marcheselli F., Moroni F., Pieri C. Apoptosis in human aortic endothelial cells induced by hyperglycemic condition involves mitochondrial depolarization and is prevented by N-acetyl-l-cysteine. Metabolism 2002, 51:1384-1388.
30. Rehman J., Li J., Orschell C.M., March K.L. Peripheral blood "endothelial progenitor cells" are derived from monocyte/macrophages and secrete angiogenic growth factors. Circulation 2003, 107:1164-1169.
31. Schachinger V., Aicher A., Dobert N., Rover R., Diener J., Fichtlscherer S., Assmus B., Seeger F.H., Menzel C., Brenner W., Dimmeler S., Zeiher A.M. Pilot trial on determinants of progenitor cell recruitment to the infarcted human myocardium. Circulation 2008, 118:1425-1432.
32. Schachinger V., Assmus B., Britten M.B., Honold J., Lehmann R., Teupe C., Abolmaali N.D., Vogl T.J., Hofmann W.K., Martin H., Dimmeler S., Zeiher A.M. Transplantation of progenitor cells and regeneration enhancement in acute myocardial infarction: final one-year results of the TOPCARE-AMI. Trial. J. Am. Coll. Cardiol. 2004, 44:1690-1699.
33. Tepper O.M., Galiano R.D., Capla J.M., Kalka C., Gagne P.J., Jacobowitz G.R., Levine J.P., Gurtner G.C. Human endothelial progenitor cells from type II diabetics exhibit impaired proliferation, adhesion, and incorporation into vascular structures. Circulation 2002, 106:2781-2786.
34. Urbich C., Dimmeler S. Endothelial progenitor cells functional characterization. Trends Cardiovasc. Med. 2004, 14:318-322.
35. Ursini F., Maiorino M., Brigelius-Flohe R., Aumann K.D., Roveri A., Schomburg D., Flohe L. Diversity of glutathione peroxidases. Methods Enzymol. 1995, 252:38-53.
36. Vasa M., Fichtlscherer S., Adler K., Aicher A., Martin H., Zeiher A.M., Dimmeler S. Increase in circulating endothelial progenitor cells by statin therapy in patients with stable coronary artery disease. Circulation 2001, 103:2885-2890.
37. Wang X.X., Zhang F.R., Shang Y.P., Zhu J.H., Xie X.D., Tao Q.M., Zhu J.H., Chen J.Z. Transplantation of autologous endothelial progenitor cells may be beneficial in patients with idiopathic pulmonary arterial hypertension: a pilot randomized controlled trial. J. Am. Coll. Cardiol. 2007, 49:1566-1571.