Wiskott-Aldrich Syndrome causing mutation, Pro373Ser restricts conformational changes essential for WASP activity in T-cells

Biochimica et Biophysica Acta - Molecular Basis of Disease

Volumn 1842, Issue 4, 2014, Pages 623-634

  Jain, Neeraj ^a   George, Bhawana ^a   Thanabalu, Thirumaran ^a  

^a NANYANG TECHNOLOGICAL UNIVERSITY   (Singapore)

Author keywords

Actin cytoskeleton; Cell migration; IL 2 expression; Immunodeficiency; T cell activation

Indexed keywords

INTERLEUKIN 2; WISKOTT ALDRICH SYNDROME PROTEIN;

ARTICLE; CHEMOTAXIS; CONFORMATION; CONFORMATIONAL TRANSITION; HUMAN; HUMAN CELL; MEMBRANE; MUTANT; MUTATION; NONHUMAN; POINT MUTATION; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION; WISKOTT ALDRICH SYNDROME; YEAST;

ACTIN CYTOSKELETON; CELL MIGRATION; IL-2 EXPRESSION; IMMUNODEFICIENCY; T-CELL ACTIVATION;

CARRIER PROTEINS; CHEMOTAXIS, LEUKOCYTE; HUMANS; IMMUNOLOGICAL SYNAPSES; INTERLEUKIN-2; JURKAT CELLS; LYMPHOCYTE ACTIVATION; MUTATION; PHOSPHORYLATION; PROTEIN CONFORMATION; T-LYMPHOCYTES; WISKOTT-ALDRICH SYNDROME; WISKOTT-ALDRICH SYNDROME PROTEIN;

EID: 84893517019     PISSN: 09254439     EISSN: 1879260X     Source Type: Journal    
DOI: 10.1016/j.bbadis.2014.01.006     Document Type: Article

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