Identification of a negative feedback loop between cyclic di-GMP-induced levels of IFI16 and p202 cytosolic DNA sensors and STING

Innate Immunity

Volumn 20, Issue 7, 2014, Pages 751-759

  Panchanathan, Ravichandran ^a,b   Liu, Hongzhu ^a,b   Xin, Duan ^a   Choubey, Divaker ^a,b  

^a UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

c di GMP; DNA sensors; IFI16; IFNs; p202; second messenger; STING

Indexed keywords

ADAPTOR PROTEIN; CYCLIC DI GMP; DNA; INTERFERON; INTERFERON REGULATORY FACTOR 3; PROTEIN; PROTEIN IFI 16; PROTEIN P202; PROTEIN STING; TANK BINDING KINASE 1; UNCLASSIFIED DRUG; BIS(3',5')-CYCLIC DIGUANYLIC ACID; CYCLIC GMP; IFI16 PROTEIN, HUMAN; IFI16 PROTEIN, MOUSE; IFI202B PROTEIN, MOUSE; MEMBRANE PROTEIN; MPYS PROTEIN, HUMAN; MPYS PROTEIN, MOUSE; NUCLEAR PROTEIN; PHOSPHOPROTEIN; SIGNAL PEPTIDE; TP53BP1 PROTEIN, HUMAN;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; FEEDBACK SYSTEM; HUMAN; HUMAN CELL; MACROPHAGE; MOLECULAR BIOLOGY; MONOCYTE; MOUSE; NEGATIVE FEEDBACK; NONHUMAN; PROTEIN EXPRESSION; SECOND MESSENGER; SIGNAL TRANSDUCTION; SPLEEN CELL; STEADY STATE; ANALOGS AND DERIVATIVES; ANIMAL; C57BL MOUSE; CELL LINE; CYTOSOL; DRUG EFFECTS; GENE SILENCING; GENETICS; METABOLISM;

ANIMALS; CELL LINE; CYCLIC GMP; CYTOSOL; DNA; FEEDBACK, PHYSIOLOGICAL; GENE KNOCKDOWN TECHNIQUES; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; NUCLEAR PROTEINS; PHOSPHOPROTEINS; SIGNAL TRANSDUCTION;

EID: 84893483360     PISSN: 17534259     EISSN: 17534267     Source Type: Journal    
DOI: 10.1177/1753425913507097     Document Type: Article

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