Metformin accumulation: Lactic acidosis and high plasmatic metformin levels in a retrospective case series of 66 patients on chronic therapy

Clinical Toxicology

Volumn 52, Issue 2, 2014, Pages 129-135

  Vecchio, S ^a   Giampreti, A ^a   Petrolini, V M ^a   Lonati, D ^a   Protti, A ^b   Papa, P ^c   Rognoni, C ^a   Valli, A ^c   Rocchi, L ^c   Rolandi, L ^c   Manzo, L ^a   Locatelli, C A ^a  

^a UNIVERSITY OF PAVIA   (Italy)

^b FONDAZIONE IRCCS CA GRANDA OSPEDALE MAGGIORE POLICLINICO   (Italy)

^c FONDAZIONE IRCCS POLICLINICO SAN MATTEO   (Italy)

Author keywords

Accumulation; Adverse drug reaction; Lactic acidosis; Metformin

Indexed keywords

CREATININE; LACTIC ACID; METFORMIN;

ACUTE KIDNEY FAILURE; ADULT; AGED; ARTICLE; CHRONIC DRUG ADMINISTRATION; CORRELATION ANALYSIS; CREATININE BLOOD LEVEL; DRUG ACCUMULATION; DRUG BLOOD LEVEL; DRUG INDICATION; DRUG MECHANISM; FEMALE; GASTROENTERITIS; GASTROINTESTINAL SYMPTOM; HOSPITAL ADMISSION; HUMAN; LACTATE BLOOD LEVEL; LACTIC ACIDOSIS; MAJOR CLINICAL STUDY; MALE; MEDICAL HISTORY; MORTALITY; NON INSULIN DEPENDENT DIABETES MELLITUS; OBSERVATIONAL STUDY; RECOMMENDED DRUG DOSE; RETROSPECTIVE STUDY; VERY ELDERLY;

ACIDOSIS, LACTIC; ACUTE KIDNEY INJURY; ADULT; AGED; AGED, 80 AND OVER; CHRONIC DISEASE; CREATININE; FEMALE; HUMANS; HYDROGEN-ION CONCENTRATION; LACTIC ACID; MALE; METFORMIN; MIDDLE AGED; RENAL DIALYSIS; RETROSPECTIVE STUDIES;

EID: 84893467321     PISSN: 15563650     EISSN: 15569519     Source Type: Journal    
DOI: 10.3109/15563650.2013.860985     Document Type: Article

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