Deletion of acetyl-CoA synthetases I and II increases production of 3-hydroxypropionate by the metabolically-engineered hyperthermophile Pyrococcus furiosus

Metabolic Engineering

Volumn 22, Issue , 2014, Pages 83-88

  Thorgersen, Michael P ^a   Lipscomb, Gina L ^a   Schut, Gerrit J ^a   Kelly, Robert M ^b   Adams, Michael W W ^a  

^a University of Georgia ^*  (United States)

^b North Carolina State University   (United States)

Author keywords

3 Hydroxypropionate; Acetyl CoA synthetase; Electrofuels; Metallosphaera sedula

Indexed keywords

3-HYDROXYPROPIONATE; ELECTROFUELS; HYPERTHERMOPHILES; HYPERTHERMOPHILIC ARCHAEON; METALLOSPHAERA SEDULA; PRODUCTION STRAIN; PYROCOCCUS FURIOSUS; SYNTHETASES;

CARBON DIOXIDE; METABOLIC ENGINEERING;

MICROORGANISMS;

ACETYL COENZYME A SYNTHETASE; ACETYL COENZYME A SYNTHETASE 1; ACETYL COENZYME A SYNTHETASE 2; COENZYME A; HYDRACRYLIC ACID; MALONYL COENZYME A; MALTOSE; PROPIONYL COENZYME A; UNCLASSIFIED DRUG; ARCHAEAL PROTEIN; LACTIC ACID; LONG CHAIN FATTY ACID COENZYME A LIGASE;

ARTICLE; BACTERIAL GENE; BACTERIAL GROWTH; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DELETION MUTANT; GENE DELETION; GLYCOLYSIS; HETEROLOGOUS EXPRESSION; HYPERTHERMOPHILE; METABOLIC ENGINEERING; METALLOSPHAERA SEDULA; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PYROCOCCUS FURIOSUS; TEMPERATURE; ANALOGS AND DERIVATIVES; GENETICS; METABOLISM; PROCEDURES;

ARCHAEAL PROTEINS; COENZYME A LIGASES; GENE DELETION; LACTIC ACID; METABOLIC ENGINEERING; PYROCOCCUS FURIOSUS;

EID: 84893443107     PISSN: 10967176     EISSN: 10967184     Source Type: Journal    
DOI: 10.1016/j.ymben.2013.12.006     Document Type: Article

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