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Volumn 10, Issue , 2014, Pages 134-140

Physalin H from Solanum nigrum as an Hh signaling inhibitor blocks GLI1-DNA-complex formation

Author keywords

Hedgehog inhibitor; Hedgehog signal; Natural products; Physalins; Solanum nigrum

Indexed keywords


EID: 84893412709     PISSN: None     EISSN: 18605397     Source Type: Journal    
DOI: 10.3762/bjoc.10.10     Document Type: Article
Times cited : (33)

References (32)
  • 1
    • 57049089995 scopus 로고    scopus 로고
    • doi:10.1016/j.devcel.2008.11.010
    • Jiang, J.; Hui, C.-c. Dev. Cell 2008, 15, 801-812. doi:10.1016/j.devcel. 2008.11.010
    • (2008) Dev. Cell , vol.15 , pp. 801-812
    • Jiang, J.1    Hui, C.-C.2
  • 2
    • 34247857432 scopus 로고    scopus 로고
    • Pathways of signal transduction employed by vertebrate Hedgehogs
    • DOI 10.1042/BJ20061723
    • Riobo, N. A.; Manning, D. R. Biochem. J. 2007, 403, 369-379. doi:10.1042/BJ20061723 (Pubitemid 46706966)
    • (2007) Biochemical Journal , vol.403 , Issue.3 , pp. 369-379
    • Riobo, N.A.1    Manning, D.R.2
  • 4
    • 0027423758 scopus 로고
    • doi:10.1126/science.8378770 See for the X-ray structure of GLI-DNA complex.
    • Pavletich, N. P.; Pabo, C. O. Science 1993, 261, 1701-1707. doi:10.1126/science.8378770 See for the X-ray structure of GLI-DNA complex.
    • (1993) Science , vol.261 , pp. 1701-1707
    • Pavletich, N.P.1    Pabo, C.O.2
  • 6
    • 33751549095 scopus 로고    scopus 로고
    • Targeting the Hedgehog pathway in cancer
    • DOI 10.1038/nrd2086, PII NRD2086
    • Rubin, L. L.; de Sauvage, F. J. Nat. Rev. Drug Discovery 2006, 5, 1026-1033. doi:10.1038/nrd2086 (Pubitemid 44835129)
    • (2006) Nature Reviews Drug Discovery , vol.5 , Issue.12 , pp. 1026-1033
    • Rubin, L.L.1    De Sauvage, F.J.2
  • 8
    • 0036829397 scopus 로고    scopus 로고
    • Inhibition of Hedgehog signaling by direct binding of cyclopamine to Smoothened
    • DOI 10.1101/gad.1025302
    • Chen, J. K.; Taipale, J.; Cooper, M. K.; Beachy, P. A. Genes Dev. 2002, 16, 2743-2748. doi:10.1101/gad.1025302 (Pubitemid 35253140)
    • (2002) Genes and Development , vol.16 , Issue.21 , pp. 2743-2748
    • Chen, J.K.1    Taipale, J.2    Cooper, M.K.3    Beachy, P.A.4
  • 29
    • 0000064713 scopus 로고
    • doi:10.1016/S0040-4020(01)93024-8
    • Kawai, M.; Matsuura, T. Tetrahedron 1970, 26, 1743-1745. doi:10.1016/S0040-4020(01)93024-8
    • (1970) Tetrahedron , vol.26 , pp. 1743-1745
    • Kawai, M.1    Matsuura, T.2
  • 31
    • 1842839986 scopus 로고    scopus 로고
    • Expression of the PTCH1 tumor suppressor gene is regulated by alternative promoters and a single functional Gli-binding site
    • DOI 10.1016/j.gene.2004.01.010, PII S0378111904000368
    • Ågren, M.; Kogerman, P.; Kleman, M. I.; Wessling, M.; Toftgård, R. Gene 2004, 330, 101-114. doi:10.1016/j.gene.2004.01.010 (Pubitemid 38490423)
    • (2004) Gene , vol.330 , Issue.1-2 , pp. 101-114
    • Agren, M.1    Kogerman, P.2    Kleman, M.I.3    Wessling, M.4    Toftgard, R.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.