메뉴 건너뛰기




Volumn 35, Issue 2, 2014, Pages 479-488

MYCN and survivin cooperatively contribute to malignant transformation of fibroblasts

Author keywords

[No Author keywords available]

Indexed keywords

HYPOXIA INDUCIBLE FACTOR 1ALPHA; SURVIVIN;

EID: 84893367336     PISSN: 01433334     EISSN: 14602180     Source Type: Journal    
DOI: 10.1093/carcin/bgt341     Document Type: Article
Times cited : (9)

References (55)
  • 1
    • 0034910622 scopus 로고    scopus 로고
    • Molecular genetics of small cell lung carcinoma
    • Wistuba,I.I. et al. (2001) Molecular genetics of small cell lung carcinoma. Semin Oncol., 28(2 Suppl 4), 3-13.
    • (2001) Semin Oncol. , vol.28 , Issue.2 SUPPL. 4 , pp. 3-13
    • Wistuba, I.I.1
  • 2
    • 30044451287 scopus 로고    scopus 로고
    • Combined microarray analysis of small cell lung cancer reveals altered apoptotic balance and distinct expression signatures of MYC family gene amplification
    • Kim,Y.H. et al. (2006) Combined microarray analysis of small cell lung cancer reveals altered apoptotic balance and distinct expression signatures of MYC family gene amplification. Oncogene, 25, 130-138.
    • (2006) Oncogene , vol.25 , pp. 130-138
    • Kim, Y.H.1
  • 3
    • 0021261878 scopus 로고
    • Amplification of N-myc in untreated human neuroblastomas correlates with advanced disease stage
    • Brodeur,G.M. et al. (1984) Amplification of N-myc in untreated human neuroblastomas correlates with advanced disease stage. Science, 224, 1121-1124.
    • (1984) Science , vol.224 , pp. 1121-1124
    • Brodeur, G.M.1
  • 4
    • 0025979843 scopus 로고
    • Clinical relevance of tumor cell ploidy and N-myc gene amplification in childhood neuroblastoma: a Pediatric Oncology Group study
    • Look,A.T. et al. (1991) Clinical relevance of tumor cell ploidy and N-myc gene amplification in childhood neuroblastoma: a Pediatric Oncology Group study. J. Clin. Oncol., 9, 581-591.
    • (1991) J. Clin. Oncol. , vol.9 , pp. 581-591
    • Look, A.T.1
  • 5
    • 63749118521 scopus 로고    scopus 로고
    • Outcome prediction in pediatric medulloblastoma based on DNA copy-number aberrations of chromosomes 6q and 17q and the MYC and MYCN loci
    • Pfister,S. et al. (2009) Outcome prediction in pediatric medulloblastoma based on DNA copy-number aberrations of chromosomes 6q and 17q and the MYC and MYCN loci. J. Clin. Oncol., 27, 1627-1636.
    • (2009) J. Clin. Oncol. , vol.27 , pp. 1627-1636
    • Pfister, S.1
  • 6
    • 14144250455 scopus 로고    scopus 로고
    • The p53 regulatory gene MDM2 is a direct transcriptional target of MYCN in neuroblastoma
    • Slack,A. et al. (2005) The p53 regulatory gene MDM2 is a direct transcriptional target of MYCN in neuroblastoma. Proc. Natl Acad. Sci. USA, 102, 731-736.
    • (2005) Proc. Natl Acad. Sci. USA , vol.102 , pp. 731-736
    • Slack, A.1
  • 7
    • 70249085177 scopus 로고    scopus 로고
    • N-Myc down regulation induced differentiation, early cell cycle exit, and apoptosis in human malignant neuroblastoma cells having wild type or mutant p53
    • Janardhanan,R. et al. (2009) N-Myc down regulation induced differentiation, early cell cycle exit, and apoptosis in human malignant neuroblastoma cells having wild type or mutant p53. Biochem. Pharmacol., 78, 1105-1114.
    • (2009) Biochem. Pharmacol. , vol.78 , pp. 1105-1114
    • Janardhanan, R.1
  • 8
    • 77952375097 scopus 로고    scopus 로고
    • Pleiotropic role for MYCN in medulloblastoma
    • Swartling,F.J. et al. (2010) Pleiotropic role for MYCN in medulloblastoma. Genes Dev., 24, 1059-1072.
    • (2010) Genes Dev. , vol.24 , pp. 1059-1072
    • Swartling, F.J.1
  • 9
    • 84861399134 scopus 로고    scopus 로고
    • Distinct neural stem cell populations give rise to disparate brain tumors in response to N-MYC
    • Swartling,F.J. et al. (2012) Distinct neural stem cell populations give rise to disparate brain tumors in response to N-MYC. Cancer Cell, 21, 601-613.
    • (2012) Cancer Cell , vol.21 , pp. 601-613
    • Swartling, F.J.1
  • 10
    • 20044391414 scopus 로고    scopus 로고
    • Relationship between MYCN copy number and expression in rhabdomyosarcomas and correlation with adverse prognosis in the alveolar subtype
    • Williamson,D. et al. (2005) Relationship between MYCN copy number and expression in rhabdomyosarcomas and correlation with adverse prognosis in the alveolar subtype. J. Clin. Oncol., 23, 880-888.
    • (2005) J. Clin. Oncol. , vol.23 , pp. 880-888
    • Williamson, D.1
  • 11
    • 43049183354 scopus 로고    scopus 로고
    • Identification of PAX3-FKHR-regulated genes differentially expressed between alveolar and embryonal rhabdomyosarcoma: focus on MYCN as a biologically relevant target
    • Mercado,G.E. et al. (2008) Identification of PAX3-FKHR-regulated genes differentially expressed between alveolar and embryonal rhabdomyosarcoma: focus on MYCN as a biologically relevant target. Genes. Chromosomes Cancer, 47, 510-520.
    • (2008) Genes. Chromosomes Cancer , vol.47 , pp. 510-520
    • Mercado, G.E.1
  • 12
    • 57149093809 scopus 로고    scopus 로고
    • Defining the cooperative genetic changes that temporally drive alveolar rhabdomyosarcoma
    • Naini,S. et al. (2008) Defining the cooperative genetic changes that temporally drive alveolar rhabdomyosarcoma. Cancer Res., 68, 9583-9588.
    • (2008) Cancer Res. , vol.68 , pp. 9583-9588
    • Naini, S.1
  • 13
    • 34250643527 scopus 로고    scopus 로고
    • Expression of MYCN in pediatric synovial sarcoma
    • Somers,G.R. et al. (2007) Expression of MYCN in pediatric synovial sarcoma. Mod. Pathol., 20, 734-741.
    • (2007) Mod. Pathol. , vol.20 , pp. 734-741
    • Somers, G.R.1
  • 14
    • 0038444622 scopus 로고    scopus 로고
    • The requirement for evasion of programmed cell death in neuroblastomas with MYCN amplification
    • Hogarty,M.D. (2003) The requirement for evasion of programmed cell death in neuroblastomas with MYCN amplification. Cancer Lett., 197, 173-179.
    • (2003) Cancer Lett. , vol.197 , pp. 173-179
    • Hogarty, M.D.1
  • 15
    • 44449160893 scopus 로고    scopus 로고
    • N-myc augments death and attenuates protective effects of Bcl-2 in trophically stressed neuroblastoma cells
    • Ushmorov,A. et al. (2008) N-myc augments death and attenuates protective effects of Bcl-2 in trophically stressed neuroblastoma cells. Oncogene, 27, 3424-3434.
    • (2008) Oncogene , vol.27 , pp. 3424-3434
    • Ushmorov, A.1
  • 16
    • 0037267333 scopus 로고    scopus 로고
    • Validating survivin as a cancer therapeutic target
    • Altieri,D.C. (2003) Validating survivin as a cancer therapeutic target. Nat. Rev. Cancer, 3, 46-54.
    • (2003) Nat. Rev. Cancer , vol.3 , pp. 46-54
    • Altieri, D.C.1
  • 17
    • 52649172153 scopus 로고    scopus 로고
    • Survivin: key regulator of mitosis and apoptosis and novel target for cancer therapeutics
    • Mita,A.C. et al. (2008) Survivin: key regulator of mitosis and apoptosis and novel target for cancer therapeutics. Clin. Cancer Res., 14, 5000-5005.
    • (2008) Clin. Cancer Res. , vol.14 , pp. 5000-5005
    • Mita, A.C.1
  • 18
    • 0033600283 scopus 로고    scopus 로고
    • Gain of chromosome arm 17q and adverse outcome in patients with neuroblastoma
    • Bown,N. et al. (1999) Gain of chromosome arm 17q and adverse outcome in patients with neuroblastoma. N. Engl. J. Med., 340, 1954-1961.
    • (1999) N. Engl. J. Med. , vol.340 , pp. 1954-1961
    • Bown, N.1
  • 19
    • 33746378618 scopus 로고    scopus 로고
    • Survivin mRNA levels are associated with biology of disease and patient survival in neuroblastoma: a report from the children's oncology group
    • Miller,M.A. et al. (2006) Survivin mRNA levels are associated with biology of disease and patient survival in neuroblastoma: a report from the children's oncology group. J. Pediatr. Hematol. Oncol., 28, 412-417.
    • (2006) J. Pediatr. Hematol. Oncol. , vol.28 , pp. 412-417
    • Miller, M.A.1
  • 20
    • 0034779647 scopus 로고    scopus 로고
    • Survivin inhibition induces human neural tumor cell death through caspase-independent and -dependent pathways
    • Shankar,S.L. et al. (2001) Survivin inhibition induces human neural tumor cell death through caspase-independent and -dependent pathways. J. Neurochem., 79, 426-436.
    • (2001) J. Neurochem. , vol.79 , pp. 426-436
    • Shankar, S.L.1
  • 21
    • 84855957229 scopus 로고    scopus 로고
    • Knockdown of survivin (BIRC5) causes apoptosis in neuroblastoma via mitotic catastrophe
    • Lamers,F. et al. (2011) Knockdown of survivin (BIRC5) causes apoptosis in neuroblastoma via mitotic catastrophe. Endocr. Relat. Cancer, 18, 657-668.
    • (2011) Endocr. Relat. Cancer , vol.18 , pp. 657-668
    • Lamers, F.1
  • 22
    • 23044445753 scopus 로고    scopus 로고
    • Survivin is a negative prognostic marker in medulloblastoma
    • Pizem,J. et al. (2005) Survivin is a negative prognostic marker in medulloblastoma. Neuropathol. Appl. Neurobiol., 31, 422-428.
    • (2005) Neuropathol. Appl. Neurobiol. , vol.31 , pp. 422-428
    • Pizem, J.1
  • 23
    • 33751042197 scopus 로고    scopus 로고
    • Histopathological prognostic factors in medulloblastoma: high expression of survivin is related to unfavourable outcome
    • Haberler,C. et al. (2006) Histopathological prognostic factors in medulloblastoma: high expression of survivin is related to unfavourable outcome. Eur. J. Cancer, 42, 2996-3003.
    • (2006) Eur. J. Cancer , vol.42 , pp. 2996-3003
    • Haberler, C.1
  • 24
    • 33144470613 scopus 로고    scopus 로고
    • Survivin-directed RNA interference cocktail is a potent suppressor of tumour growth in vivo
    • Caldas,H. et al. (2006) Survivin-directed RNA interference cocktail is a potent suppressor of tumour growth in vivo. J. Med. Genet., 43, 119-128.
    • (2006) J. Med. Genet. , vol.43 , pp. 119-128
    • Caldas, H.1
  • 25
    • 79952108411 scopus 로고    scopus 로고
    • Expression of survivin detected by immunohistochemistry in the cytoplasm and in the nucleus is associated with prognosis of leiomyosarcoma and synovial sarcoma patients
    • Taubert,H. et al. (2010) Expression of survivin detected by immunohistochemistry in the cytoplasm and in the nucleus is associated with prognosis of leiomyosarcoma and synovial sarcoma patients. BMC Cancer, 10, 65.
    • (2010) BMC Cancer , vol.10 , pp. 65
    • Taubert, H.1
  • 26
    • 85006768050 scopus 로고
    • The metabolism of tumors in the body
    • Warburg,O. et al. (1927) The metabolism of tumors in the body. J. Gen. Physiol., 8, 519-530.
    • (1927) J. Gen. Physiol. , vol.8 , pp. 519-530
    • Warburg, O.1
  • 27
    • 79952284127 scopus 로고    scopus 로고
    • Hallmarks of cancer: the next generation
    • Hanahan,D. et al. (2011) Hallmarks of cancer: the next generation. Cell, 144, 646-674.
    • (2011) Cell , vol.144 , pp. 646-674
    • Hanahan, D.1
  • 28
    • 84866127673 scopus 로고    scopus 로고
    • Metabolic reprogramming of the tumor
    • Ferreira,L.M. et al. (2012) Metabolic reprogramming of the tumor. Oncogene, 31, 3999-4011.
    • (2012) Oncogene , vol.31 , pp. 3999-4011
    • Ferreira, L.M.1
  • 29
    • 78650403118 scopus 로고    scopus 로고
    • Combinatorial regulation of neuroblastoma tumor progression by N-Myc and hypoxia inducible factor HIF-1alpha
    • Qing,G. et al. (2010) Combinatorial regulation of neuroblastoma tumor progression by N-Myc and hypoxia inducible factor HIF-1alpha. Cancer Res., 70, 10351-10361.
    • (2010) Cancer Res. , vol.70 , pp. 10351-10361
    • Qing, G.1
  • 30
    • 84885178346 scopus 로고    scopus 로고
    • BIRC5/Survivin enhances aerobic glycolysis and drug resistance by altered regulation of the mitochondrial fusion/fission machinery
    • Hagenbuchner,J. et al. (2013) BIRC5/Survivin enhances aerobic glycolysis and drug resistance by altered regulation of the mitochondrial fusion/fission machinery. Oncogene, 32, 4748-4757.
    • (2013) Oncogene , vol.32 , pp. 4748-4757
    • Hagenbuchner, J.1
  • 31
    • 0029127219 scopus 로고
    • Current pathologic methods for measuring intratumoral microvessel density within breast carcinoma and other solid tumors
    • Weidner,N. (1995) Current pathologic methods for measuring intratumoral microvessel density within breast carcinoma and other solid tumors. Breast Cancer Res. Treat., 36, 169-180.
    • (1995) Breast Cancer Res. Treat. , vol.36 , pp. 169-180
    • Weidner, N.1
  • 32
    • 0034652620 scopus 로고    scopus 로고
    • High lactate levels predict likelihood of metastases, tumor recurrence, and restricted patient survival in human cervical cancers
    • Walenta,S. et al. (2000) High lactate levels predict likelihood of metastases, tumor recurrence, and restricted patient survival in human cervical cancers. Cancer Res., 60, 916-921.
    • (2000) Cancer Res. , vol.60 , pp. 916-921
    • Walenta, S.1
  • 33
    • 0023148557 scopus 로고
    • Neoplastic transformation by the human gene N-myc
    • Small,M.B. et al. (1987) Neoplastic transformation by the human gene N-myc. Mol. Cell. Biol., 7, 1638-1645.
    • (1987) Mol. Cell. Biol. , vol.7 , pp. 1638-1645
    • Small, M.B.1
  • 34
    • 0344156843 scopus 로고
    • The chemical constitution of respiration ferment
    • Warburg,O. (1928) The chemical constitution of respiration ferment. Science, 68, 437-443.
    • (1928) Science , vol.68 , pp. 437-443
    • Warburg, O.1
  • 35
    • 8144228566 scopus 로고    scopus 로고
    • Why do cancers have high aerobic glycolysis?
    • Gatenby,R.A. et al. (2004) Why do cancers have high aerobic glycolysis? Nat. Rev. Cancer, 4, 891-899.
    • (2004) Nat. Rev. Cancer , vol.4 , pp. 891-899
    • Gatenby, R.A.1
  • 36
    • 33744783432 scopus 로고    scopus 로고
    • Attenuation of LDH-A expression uncovers a link between glycolysis, mitochondrial physiology, and tumor maintenance
    • Fantin,V.R. et al. (2006) Attenuation of LDH-A expression uncovers a link between glycolysis, mitochondrial physiology, and tumor maintenance. Cancer Cell, 9, 425-434.
    • (2006) Cancer Cell , vol.9 , pp. 425-434
    • Fantin, V.R.1
  • 37
    • 0033974001 scopus 로고    scopus 로고
    • The p21(WAF1/CIP1) promoter is methylated in Rat-1 cells: stable restoration of p53-dependent p21(WAF1/CIP1) expression after transfection of a genomic clone containing the p21(WAF1/CIP1) gene
    • Allan,L.A. et al. (2000) The p21(WAF1/CIP1) promoter is methylated in Rat-1 cells: stable restoration of p53-dependent p21(WAF1/CIP1) expression after transfection of a genomic clone containing the p21(WAF1/CIP1) gene. Mol. Cell. Biol., 20, 1291-1298.
    • (2000) Mol. Cell. Biol. , vol.20 , pp. 1291-1298
    • Allan, L.A.1
  • 38
    • 79960847016 scopus 로고    scopus 로고
    • Advances in sarcoma genomics and new therapeutic targets
    • Taylor,B.S. et al. (2011) Advances in sarcoma genomics and new therapeutic targets. Nat. Rev. Cancer, 11, 541-557.
    • (2011) Nat. Rev. Cancer , vol.11 , pp. 541-557
    • Taylor, B.S.1
  • 39
    • 84866047749 scopus 로고    scopus 로고
    • A "twist box" code of p53 inactivation: twist box: p53 interaction promotes p53 degradation
    • Piccinin,S. et al. (2012) A "twist box" code of p53 inactivation: twist box: p53 interaction promotes p53 degradation. Cancer Cell, 22, 404-415.
    • (2012) Cancer Cell , vol.22 , pp. 404-415
    • Piccinin, S.1
  • 40
    • 0033588883 scopus 로고    scopus 로고
    • Rhabdomyosarcoma-working out the pathways
    • Merlino,G. et al. (1999) Rhabdomyosarcoma-working out the pathways. Oncogene, 18, 5340-5348.
    • (1999) Oncogene , vol.18 , pp. 5340-5348
    • Merlino, G.1
  • 41
    • 2642528708 scopus 로고    scopus 로고
    • Altered expression and molecular abnormalities of cell-cycle-regulatory proteins in rhabdomyosarcoma
    • Takahashi,Y. et al. (2004) Altered expression and molecular abnormalities of cell-cycle-regulatory proteins in rhabdomyosarcoma. Mod. Pathol., 17, 660-669.
    • (2004) Mod. Pathol. , vol.17 , pp. 660-669
    • Takahashi, Y.1
  • 42
    • 33644552409 scopus 로고    scopus 로고
    • Increased frequency of aberrations in the p53/MDM2/p14(ARF) pathway in neuroblastoma cell lines established at relapse
    • Carr,J. et al. (2006) Increased frequency of aberrations in the p53/MDM2/p14(ARF) pathway in neuroblastoma cell lines established at relapse. Cancer Res., 66, 2138-2145.
    • (2006) Cancer Res. , vol.66 , pp. 2138-2145
    • Carr, J.1
  • 43
    • 76749166680 scopus 로고    scopus 로고
    • High Frequency of p53/MDM2/p14ARF Pathway Abnormalities in Relapsed Neuroblastoma
    • Carr-Wilkinson,J. et al. (2010) High Frequency of p53/MDM2/p14ARF Pathway Abnormalities in Relapsed Neuroblastoma. Clin. Cancer Res., 16, 1108-1118.
    • (2010) Clin. Cancer Res. , vol.16 , pp. 1108-1118
    • Carr-Wilkinson, J.1
  • 44
    • 0028076921 scopus 로고
    • Altered growth and phenotype in clonal mycN transfectants of the SK-N-SH neuroblastoma cell line
    • Gross,N. et al. (1994) Altered growth and phenotype in clonal mycN transfectants of the SK-N-SH neuroblastoma cell line. Int. J. Cancer, 59, 141-148.
    • (1994) Int. J. Cancer , vol.59 , pp. 141-148
    • Gross, N.1
  • 45
    • 0029743372 scopus 로고    scopus 로고
    • Conditional expression of N-myc in human neuroblastoma cells increases expression of alpha-prothymosin and ornithine decarboxylase and accelerates progression into S-phase early after mitogenic stimulation of quiescent cells
    • Lutz,W. et al. (1996) Conditional expression of N-myc in human neuroblastoma cells increases expression of alpha-prothymosin and ornithine decarboxylase and accelerates progression into S-phase early after mitogenic stimulation of quiescent cells. Oncogene, 13, 803-812.
    • (1996) Oncogene , vol.13 , pp. 803-812
    • Lutz, W.1
  • 46
    • 33750827351 scopus 로고    scopus 로고
    • The case for Survivin as mitotic regulator
    • Lens,S.M. et al. (2006) The case for Survivin as mitotic regulator. Curr. Opin. Cell Biol., 18, 616-622.
    • (2006) Curr. Opin. Cell Biol. , vol.18 , pp. 616-622
    • Lens, S.M.1
  • 47
    • 33750611276 scopus 로고    scopus 로고
    • The case for survivin as a regulator of microtubule dynamics and cell-death decisions
    • Altieri,D.C. (2006) The case for survivin as a regulator of microtubule dynamics and cell-death decisions. Curr. Opin. Cell Biol., 18, 609-615.
    • (2006) Curr. Opin. Cell Biol. , vol.18 , pp. 609-615
    • Altieri, D.C.1
  • 48
    • 0038376119 scopus 로고    scopus 로고
    • Survivin is required for a sustained spindle checkpoint arrest in response to lack of tension
    • Lens,S.M. et al. (2003) Survivin is required for a sustained spindle checkpoint arrest in response to lack of tension. EMBO J., 22, 2934-2947.
    • (2003) EMBO J. , vol.22 , pp. 2934-2947
    • Lens, S.M.1
  • 49
    • 73649095563 scopus 로고    scopus 로고
    • IAP regulation of metastasis
    • Mehrotra,S. et al. (2010) IAP regulation of metastasis. Cancer Cell, 17, 53-64.
    • (2010) Cancer Cell , vol.17 , pp. 53-64
    • Mehrotra, S.1
  • 50
    • 78049267203 scopus 로고    scopus 로고
    • Survivin enhances motility of melanoma cells by supporting Akt activation and {alpha}5 integrin upregulation
    • McKenzie,J.A. et al. (2010) Survivin enhances motility of melanoma cells by supporting Akt activation and {alpha}5 integrin upregulation. Cancer Res., 70, 7927-7937.
    • (2010) Cancer Res. , vol.70 , pp. 7927-7937
    • McKenzie, J.A.1
  • 51
    • 0023734130 scopus 로고
    • Transfer of a functional human immune system to mice with severe combined immunodeficiency
    • Mosier,D.E. et al. (1988) Transfer of a functional human immune system to mice with severe combined immunodeficiency. Nature, 335, 256-259.
    • (1988) Nature , vol.335 , pp. 256-259
    • Mosier, D.E.1
  • 52
    • 0018905522 scopus 로고
    • The polyoma virus 100K large T-antigen is not required for the maintenance of transformation
    • Lania,L. et al. (1980) The polyoma virus 100K large T-antigen is not required for the maintenance of transformation. Virology, 101, 217-232.
    • (1980) Virology , vol.101 , pp. 217-232
    • Lania, L.1
  • 53
    • 0035953308 scopus 로고    scopus 로고
    • IFNgamma and lymphocytes prevent primary tumour development and shape tumour immunogenicity
    • Shankaran,V. et al. (2001) IFNgamma and lymphocytes prevent primary tumour development and shape tumour immunogenicity. Nature, 410, 1107-1111.
    • (2001) Nature , vol.410 , pp. 1107-1111
    • Shankaran, V.1
  • 54
    • 84863753157 scopus 로고    scopus 로고
    • The ALK(F1174L) mutation potentiates the oncogenic activity of MYCN in neuroblastoma
    • Berry,T. et al. (2012) The ALK(F1174L) mutation potentiates the oncogenic activity of MYCN in neuroblastoma. Cancer Cell, 22, 117-130.
    • (2012) Cancer Cell , vol.22 , pp. 117-130
    • Berry, T.1
  • 55
    • 57849107571 scopus 로고    scopus 로고
    • Stabilization of N-Myc is a critical function of Aurora A in human neuroblastoma
    • Otto,T. et al. (2009) Stabilization of N-Myc is a critical function of Aurora A in human neuroblastoma. Cancer Cell, 15, 67-78.
    • (2009) Cancer Cell , vol.15 , pp. 67-78
    • Otto, T.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.