Prostaglandin E2 inhibits elastogenesis in the ductus arteriosus via EP4 signaling

Circulation

Volumn 129, Issue 4, 2014, Pages 487-496

  Yokoyama, Utako ^a   Minamisawa, Susumu ^a,b,c   Shioda, Aki ^a   Ishiwata, Ryo ^a   Jin, Mei Hua ^a   Masuda, Munetaka ^a   Asou, Toshihide ^d   Sugimoto, Yukihiko ^e   Aoki, Hiroki ^f   Nakamura, Tomoyuki ^g   Ishikawa, Yoshihiro ^a,b  

^a YOKOHAMA CITY UNIVERSITY   (Japan)

^b WASEDA UNIVERSITY   (Japan)

^c JIKEI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^d KANAGAWA CHILDREN'S MEDICAL CENTER   (Japan)

^e KUMAMOTO UNIVERSITY   (Japan)

^f KURUME UNIVERSITY   (Japan)

^g KANSAI MEDICAL UNIVERSITY   (Japan)

Author keywords

Elasticity; Muscle, smooth; Pediatrics; Prostaglandins; Signal transduction

Indexed keywords

ELASTIN; PROSTAGLANDIN E RECEPTOR 4; PROSTAGLANDIN E2; PROTEIN LYSINE 6 OXIDASE;

ADENOVIRUS; ANIMAL TISSUE; AORTA; ARTICLE; CIRCULATION; CONTROLLED STUDY; DUCTUS ARTERIOSUS; ELASTIC FIBER; FETUS; HUMAN; HUMAN TISSUE; LYSOSOME; MICROSCOPY; NONHUMAN; ONCOGENE SRC; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SMOOTH MUSCLE FIBER; VASCULAR TISSUE;

ELASTICITY; MUSCLE, SMOOTH; PEDIATRICS; PROSTAGLANDINS; SIGNAL TRANSDUCTION;

ANIMALS; AORTA; CELLS, CULTURED; DINOPROSTONE; DUCTUS ARTERIOSUS; ELASTIC TISSUE; ELASTICITY; ELASTIN; HUMANS; INFANT, NEWBORN; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MODELS, ANIMAL; MYOCYTES, SMOOTH MUSCLE; PHENOTYPE; PHOSPHOLIPASE C GAMMA; PROTEIN-LYSINE 6-OXIDASE; RATS; RATS, WISTAR; RECEPTORS, PROSTAGLANDIN E, EP4 SUBTYPE; SIGNAL TRANSDUCTION; SRC-FAMILY KINASES;

EID: 84893341444     PISSN: 00097322     EISSN: 15244539     Source Type: Journal    
DOI: 10.1161/CIRCULATIONAHA.113.004726     Document Type: Article

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