-
1
-
-
84945924302
-
-
Influenza fact sheet World Health Organization 211
-
Influenza fact sheet No. 211: World Health Organization; (2009)
-
(2009)
-
-
-
2
-
-
84862003840
-
Influenza neuraminidase
-
Air, G. M. Influenza neuraminidase. Influenza Other Respi Viruses. 6(4), 245-256 (2012)
-
(2012)
Influenza Other Respi Viruses
, vol.6
, Issue.4
, pp. 245-256
-
-
Air, G.M.1
-
3
-
-
84863230485
-
A distinct lineage of influenza A virus from bats
-
Tong, S. et al. A distinct lineage of influenza A virus from bats. Proc Natl Acad Sci U S A. 109(11), 4269-4274 (2012)
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
, Issue.11
, pp. 4269-4274
-
-
Tong, S.1
-
4
-
-
33748437791
-
The structure of H5N1 avian influenza neuraminidase suggests new opportunities for drug design
-
Russell, R. J. et al. The structure of H5N1 avian influenza neuraminidase suggests new opportunities for drug design. Nature. 443(7107), 45-49 (2006)
-
(2006)
Nature
, vol.443
, Issue.7107
, pp. 45-49
-
-
Russell, R.J.1
-
5
-
-
84869233988
-
Crystal structures of two subtype N10 neuraminidase-like proteins from bat influenza A viruses reveal a diverged putative active site
-
Zhu, X. et al. Crystal structures of two subtype N10 neuraminidase-like proteins from bat influenza A viruses reveal a diverged putative active site. Proc Natl Acad Sci U S A. 109(46), 18903-18908 (2012)
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
, Issue.46
, pp. 18903-18908
-
-
Zhu, X.1
-
6
-
-
84869222897
-
Structural and functional characterization of neuraminidase-like molecule N10 derived from bat influenza A virus
-
Li, Q. et al. Structural and functional characterization of neuraminidase-like molecule N10 derived from bat influenza A virus. Proc Natl Acad Sci U S A. 109(46), 18897-18902 (2012)
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
, Issue.46
, pp. 18897-18902
-
-
Li, Q.1
-
7
-
-
84866902241
-
H1N1 2009 pandemic influenza virus: Resistance of the I223R neuraminidase mutant explained by kinetic and structural analysis
-
van der Vries, E. et al. H1N1 2009 pandemic influenza virus: resistance of the I223R neuraminidase mutant explained by kinetic and structural analysis. PLoS Pathog. 8(9), e1002914 (2012)
-
(2012)
PLoS Pathog
, vol.8
, Issue.9
, pp. e1002914
-
-
Van Der Vries, E.1
-
8
-
-
79960337244
-
Mechanism of 150-cavity formation in influenza neuraminidase
-
Amaro, R. E. et al. Mechanism of 150-cavity formation in influenza neuraminidase. Nat Commun. 2, 388 (2011)
-
(2011)
Nat Commun
, vol.2
, pp. 388
-
-
Amaro, R.E.1
-
9
-
-
77957767268
-
The 2009 pandemic H1N1 neuraminidase N1 lacks the 150-cavity in its active site
-
Li, Q. et al. The 2009 pandemic H1N1 neuraminidase N1 lacks the 150-cavity in its active site. Nat Struct Mol Biol. 17(10), 1266-1268 (2010)
-
(2011)
Nat Struct Mol Biol
, vol.17
, Issue.10
, pp. 1266-1268
-
-
Li, Q.1
-
10
-
-
84876041941
-
Plasticity of 150-loop in influenza neuraminidase explored by hamiltonian replica exchange molecular dynamics simulations
-
Han, N. &Mu, Y. Plasticity of 150-loop in influenza neuraminidase explored by hamiltonian replica exchange molecular dynamics simulations. PLoS One. 8(4), e60995 (2013)
-
(2013)
PLoS One
, vol.8
, Issue.4
, pp. e60995
-
-
Han, N.1
Mu, Y.2
-
11
-
-
84867566248
-
Synthesis and evaluation of novel 3-C-Alkylated-Neu5Ac2en derivatives as probes of influenza virus sialidase 150-loop flexibility
-
Rudrawar, S. et al. Synthesis and evaluation of novel 3-C-Alkylated-Neu5Ac2en derivatives as probes of influenza virus sialidase 150-loop flexibility. Org Biomol Chem. 10(43), 8628-8639 (2012)
-
(2012)
Org Biomol Chem
, vol.10
, Issue.43
, pp. 8628-8639
-
-
Rudrawar, S.1
-
12
-
-
78650045655
-
Novel sialic acid derivatives lock open the 150-loop of an influenza A virus group-1 sialidase
-
Rudrawar, S. et al. Novel sialic acid derivatives lock open the 150-loop of an influenza A virus group-1 sialidase. Nat Commun. 1, 113 (2010)
-
(2011)
Nat Commun
, vol.1
, pp. 113
-
-
Rudrawar, S.1
-
13
-
-
77958509160
-
Carbocycles related to oseltamivir as influenza virus group-1-specific neuraminidase inhibitors. Binding to N1 enzymes in the context of virus-like particles
-
Mohan, S., McAtamney, S., Haselhorst, T., von Itzstein, M. &Pinto, B. M. Carbocycles related to oseltamivir as influenza virus group-1-specific neuraminidase inhibitors. Binding to N1 enzymes in the context of virus-like particles. J Med Chem. 53(20), 7377-7391 (2010)
-
(2011)
J Med Chem
, vol.53
, Issue.20
, pp. 7377-7391
-
-
Mohan, S.1
McAtamney, S.2
Haselhorst, T.3
Von Itzstein, M.4
Pinto, B.M.5
-
14
-
-
77953138513
-
Analogs of zanamivir with modified C4-substituents as the inhibitors against the group-1 neuraminidases of influenza viruses
-
Wen, W. H. et al. Analogs of zanamivir with modified C4-substituents as the inhibitors against the group-1 neuraminidases of influenza viruses. Bioorg Med Chem. 18(11), 4074-4084 (2010)
-
(2011)
Bioorg Med Chem
, vol.18
, Issue.11
, pp. 4074-4084
-
-
Wen, W.H.1
-
15
-
-
84875440351
-
The influence of 150-cavity binders on the dynamics of influenza A neuraminidases as revealed by molecular dynamics simulations and combined clustering
-
Greenway, K. T., LeGresley, E. B. &Pinto, B. M. The influence of 150-cavity binders on the dynamics of influenza A neuraminidases as revealed by molecular dynamics simulations and combined clustering. PLoS One. 8(3), e59873 (2013)
-
(2013)
PLoS One
, vol.8
, Issue.3
, pp. e59873
-
-
Greenway, K.T.1
LeGresley, E.B.2
Pinto, B.M.3
-
16
-
-
67949124553
-
Characterizing loop dynamics and ligand recognition in human-And avian-type influenza neuraminidases via generalized born molecular dynamics and end-point free energy calculations
-
Amaro, R. E., Cheng, X., Ivanov, I., Xu, D. &McCammon, J. A. Characterizing loop dynamics and ligand recognition in human-And avian-type influenza neuraminidases via generalized born molecular dynamics and end-point free energy calculations. J Am Chem Soc. 131(13), 4702-4709 (2009)
-
(2009)
J Am Chem Soc
, vol.131
, Issue.13
, pp. 4702-4709
-
-
Amaro, R.E.1
Cheng, X.2
Ivanov, I.3
Xu, D.4
McCammon, J.A.5
-
17
-
-
84875763136
-
Induced opening of influenza virus neuraminidase N2 150-loop suggests an important role in inhibitor binding
-
Wu, Y. et al. Induced opening of influenza virus neuraminidase N2 150-loop suggests an important role in inhibitor binding. Sci Rep. 3, 1551 (2013)
-
(2013)
Sci Rep
, vol.3
, pp. 1551
-
-
Wu, Y.1
-
18
-
-
79953856447
-
Replication inhibition activity of carbocycles related to oseltamivir on influenza A virus in vitro
-
Niikura, M., Bance, N., Mohan, S. &Pinto, B. M. Replication inhibition activity of carbocycles related to oseltamivir on influenza A virus in vitro. Antiviral Res. 90(3), 160-163 (2011)
-
(2011)
Antiviral Res
, vol.90
, Issue.3
, pp. 160-163
-
-
Niikura, M.1
Bance, N.2
Mohan, S.3
Pinto, B.M.4
-
19
-
-
79955471904
-
Inhibitor selectivity of a new class of oseltamivir analogs against viral neuraminidase over human neuraminidase enzymes
-
Albohy, A., Mohan, S., Zheng, R. B., Pinto, B. M. &Cairo, C. W. Inhibitor selectivity of a new class of oseltamivir analogs against viral neuraminidase over human neuraminidase enzymes. Bioorg Med Chem. 19(9), 2817-2822 (2011)
-
(2011)
Bioorg Med Chem
, vol.19
, Issue.9
, pp. 2817-2822
-
-
Albohy, A.1
Mohan, S.2
Zheng, R.B.3
Pinto, B.M.4
Cairo, C.W.5
-
20
-
-
54049124684
-
Limited inhibitory effects of oseltamivir and zanamivir on human sialidases
-
Hata, K. et al. Limited inhibitory effects of oseltamivir and zanamivir on human sialidases. Antimicrob Agents Chemother. 52(10), 3484-3491 (2008)
-
(2008)
Antimicrob Agents Chemother
, vol.52
, Issue.10
, pp. 3484-3491
-
-
Hata, K.1
-
21
-
-
0035190544
-
Comparison of the activities of zanamivir, oseltamivir, and RWJ-270201 against clinical isolates of influenza virus and neuraminidase inhibitor-resistant variants
-
Gubareva, L. V., Webster, R. G. &Hayden, F. G. Comparison of the activities of zanamivir, oseltamivir, and RWJ-270201 against clinical isolates of influenza virus and neuraminidase inhibitor-resistant variants. Antimicrob Agents Chemother. 45(12), 3403-3408 (2001)
-
(2001)
Antimicrob Agents Chemother
, vol.45
, Issue.12
, pp. 3403-3408
-
-
Gubareva, L.V.1
Webster, R.G.2
Hayden, F.G.3
-
22
-
-
46249111790
-
Crystal structures of oseltamivir-resistant influenza virus neuraminidase mutants
-
Collins, P. J. et al. Crystal structures of oseltamivir-resistant influenza virus neuraminidase mutants. Nature. 453(7199), 1258-1261 (2008)
-
(2008)
Nature
, vol.453
, Issue.7199
, pp. 1258-1261
-
-
Collins, P.J.1
-
23
-
-
0027287506
-
Rational design of potent sialidase-based inhibitors of influenza virus replication
-
von Itzstein, M. et al. Rational design of potent sialidase-based inhibitors of influenza virus replication. Nature. 363(6428), 418-423 (1993)
-
(1993)
Nature
, vol.363
, Issue.6428
, pp. 418-423
-
-
Von Itzstein, M.1
-
24
-
-
34848839869
-
Synthesis of tamiflu and its phosphonate congeners possessing potent anti-influenza activity
-
Shie, J. J. et al. Synthesis of tamiflu and its phosphonate congeners possessing potent anti-influenza activity. J Am Chem Soc. 129(39), 11892-11893 (2007)
-
(2007)
J Am Chem Soc
, vol.129
, Issue.39
, pp. 11892-11893
-
-
Shie, J.J.1
-
25
-
-
0036805385
-
Comparison of colorimetric, fluorometric, and visual methods for determining anti-influenza (H1N1 and H3N2) virus activities and toxicities of compounds
-
Smee, D. F., Morrison, A. C., Barnard, D. L. &Sidwell, R. W. Comparison of colorimetric, fluorometric, and visual methods for determining anti-influenza (H1N1 and H3N2) virus activities and toxicities of compounds. J Virol Methods. 106(1), 71-79 (2002)
-
(2002)
J Virol Methods
, vol.106
, Issue.1
, pp. 71-79
-
-
Smee, D.F.1
Morrison, A.C.2
Barnard, D.L.3
Sidwell, R.W.4
-
26
-
-
0035115174
-
Cyclopentane neuraminidase inhibitors with potent in vitro anti-influenza virus activities
-
Smee, D. F., Huffman, J. H., Morrison, A. C., Barnard, D. L. &Sidwell, R. W. Cyclopentane neuraminidase inhibitors with potent in vitro anti-influenza virus activities. Antimicrob Agents Chemother. 45(3), 743-748 (2001)
-
(2001)
Antimicrob Agents Chemother
, vol.45
, Issue.3
, pp. 743-748
-
-
Smee, D.F.1
Huffman, J.H.2
Morrison, A.C.3
Barnard, D.L.4
Sidwell, R.W.5
-
27
-
-
84945945175
-
-
Sawyer, L., Isaacs, N., Bailey, S. (eds Data Collection and Processing. 556-562 (SERC Daresbury Laboratory: Warrington
-
Otwinowski, Z. &Minor, W. In: Sawyer, L., Isaacs, N., Bailey, S. (eds). Data Collection and Processing. 556-562 (SERC Daresbury Laboratory: Warrington, 1993)
-
(1993)
-
-
Otwinowski, Z.1
Minor, W.2
-
28
-
-
76449098262
-
PHENIX: A comprehensive Python-based system for macromolecular structure solution
-
Adams, P. D. et al. PHENIX: a comprehensive Python-based system for macromolecular structure solution. Acta Crystallogr D Biol Crystallogr. 66(Pt 2), 213-221 (2010)
-
(2011)
Acta Crystallogr D Biol Crystallogr
, vol.66
, Issue.2
, pp. 213-221
-
-
Adams, P.D.1
-
29
-
-
77949535720
-
Features and development of Coot
-
Emsley, P., Lohkamp, B., Scott, W. G. &Cowtan, K. Features and development of Coot. Acta Crystallogr D Biol Crystallogr. 66(Pt 4), 486-501 (2010)
-
(2011)
Acta Crystallogr D Biol Crystallogr
, vol.66
, Issue.4
, pp. 486-501
-
-
Emsley, P.1
Lohkamp, B.2
Scott, W.G.3
Cowtan, K.4
|