Control of protein concentrations in heterogeneous cell populations

2013 European Control Conference, ECC 2013

Volumn , Issue , 2013, Pages 3633-3639

  Vignoni, A ^a   Oyarzun, D A ^b   Pico, J ^a   Stan, G B ^b  

^a UNIVERSITAT POLITÈCNICA DE VALÈNCIA   (Spain)

^b IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CELL CULTURE; CELL PROLIFERATION; CELLS; CLOSED LOOP SYSTEMS; CONTROLLERS; ESCHERICHIA COLI; PHYSIOLOGICAL MODELS; PROTEINS;

CELL-TO-CELL COMMUNICATION; CLOSED-FORM EXPRESSION; INDEPENDENT CONTROL; NON-LINEAR CONTROLLERS; PIECEWISE AFFINE APPROXIMATION; PROTEIN CONCENTRATIONS; SIGNALLING MOLECULES; SYNTHETIC GENE CIRCUITS;

CELL SIGNALING;

EID: 84893224567     PISSN: None     EISSN: None     Source Type: Conference Proceeding    
DOI: 10.23919/ecc.2013.6669828     Document Type: Conference Paper

References (23)

1. M. B. Elowitz and S. Leibler, "A synthetic oscillatory network of transcriptional regulators, " Nature, vol. 403, no. 6767, pp. 335-338, Jan. 2000.
2. T. S. Gardner, C. R. Cantor, and J. J. Collins, "Construction of a genetic toggle switch in Escherichia coli, " Nature, vol. 403, no. 6767, pp. 339-342, Jan. 2000.
3. P. E. M. Purnick and R. Weiss, "The second wave of synthetic biology: from modules to systems." Nature reviews. Molecular cell biology, vol. 10, no. 6, pp. 410-22, Jun. 2009.
4. A. S. Khalil and J. J. Collins, "Synthetic biology: applications come of age." Nature reviews. Genetics, vol. 11, no. 5, pp. 367-79, May 2010.
5. D. McMillen, N. Kopell, J. Hasty, and J. Collins, "Synchronizing genetic relaxation oscillators by intercell signaling, " Proceedings of the National Academy of Sciences, vol. 99, no. 2, p. 679, 2002.
6. H. Kobayashi, M. Kaern, M. Araki, K. Chung, T. Gardner, C. Cantor, and J. Collins, "Programmable cells: interfacing natural and engineered gene networks, " Proceedings of the National Academy of Sciences of the United States of America, vol. 101, no. 22, p. 8414, 2004.
7. S. Basu, Y. Gerchman, C. Collins, F. Arnold, and R. Weiss, "A synthetic multicellular system for programmed pattern formation, " Nature, vol. 434, no. 7037, pp. 1130-1134, 2005.
8. F. K. Balagadd́e, H. Song, J. Ozaki, C. H. Collins, M. Barnet, F. H. Arnold, S. R. Quake, and L. You, "A synthetic Escherichia coli predator-prey ecosystem." Molecular systems biology, vol. 4, p. 187, Jan. 2008.
9. M. B. Elowitz, A. J. Levine, E. D. Siggia, and P. S. Swain, "Stochastic Gene Expression in a Single Cell, " Science, vol. 297, no. 5584, pp. 1183-1186, Aug. 2002.
10. C. Zechner, J. Ruess, P. Krenn, S. Pelet, M. Peter, J. Lygeros, and H. Koeppl, "Moment-Based Inference Predicts Bimodality in Transient Gene Expression, " PNAS, vol. 109, no. 21, pp. 8340-8345, 2012.
11. P. S. Swain, M. B. Elowitz, and E. D. Siggia, "Intrinsic and extrinsic contributions to stochasticity in gene expression." Proceedings of the National Academy of Sciences of the United States of America, vol. 99, no. 20, pp. 12795-800, Oct. 2002.
12. F. Esfandiari and H. Khalil, "Stability analysis of a continuous implementation of variable structure control, " Automatic Control, IEEE Transactions on, vol. 36, no. 5, pp. 616-620, 1991.
13. A. Vignoni, J. Pićo, F. Garelli, and H. De Battista, "Sliding mode reference conditioning for coordination in swarms of non-identical multiagent systems." in Variable Structure Systems, 12th IEEE International Workshop on, 2012, pp. 231-236.
14. C. Fuqua, M. Parsek, and E. Greenberg, "Regulation of gene expression by cell-to-cell communication: acyl-homoserine lactone quorum sensing, " Annual review of genetics, vol. 35, no. 1, pp. 439-468, 2001.
15. K. A. Egland and E. P. Greenberg, "Conversion of the vibrio fischeri transcriptional activator, LuxR, to a repressor, " Journal of Bacteriology, vol. 182, no. 3, pp. 805-811, Feb. 2000.
16. H. Kaplan and E. Greenberg, "Diffusion of autoinducer is involved in regulation of the vibrio fischeri luminescence system." Journal of Bacteriology, vol. 163, no. 3, pp. 1210-1214, 1985.
17. A. L. Schaefer, D. L. Val, B. L. Hanzelka, J. E. Cronan, and E. P. Greenberg, "Generation of cell-to-cell signals in quorum sensing: acyl homoserine lactone synthase activity of a purified vibrio fischeri luxi protein, " Proceedings of the National Academy of Sciences, vol. 93, no. 18, pp. 9505-9509, 1996.
18. P. Mina, M. di Bernardo, N. J. Savery, and K. Tsaneva-Atanasova, "Modelling emergence of oscillations in communicating bacteria: A structured approach from one to many cells, " Journal of The Royal Society Interface, vol. 10, no. 78, 2013.
19. M. Kærn, T. C. Elston, W. J. Blake, and J. J. Collins, "Stochasticity in gene expression: from theories to phenotypes, " Nature Reviews Genetics, vol. 6, no. 6, pp. 451-464, 2005.
20. C. Smith, H. Song, and L. You, "Signal discrimination by differential regulation of protein stability in quorum sensing, " Journal of molecular biology, vol. 382, no. 5, p. 1290, 2008.
21. M. Weber, J. Buceta et al., "Dynamics of the quorum sensing switch: stochastic and non-stationary effects, " BMC systems biology, vol. 7, no. 1, p. 6, 2013.
22. R. G. Egbert and E. Klavins, "Fine-tuning gene networks using simple sequence repeats, " Proceedings of the National Academy of Sciences of the United States of America, Aug. 2012.
23. N. E. Buchler and F. R. Cross, "Protein sequestration generates a flexible ultrasensitive response in a genetic network, " Molecular Systems Biology, vol. 5, 2009.