MRNA deadenylation by Pan2-Pan3

Biochemical Society Transactions

Volumn 42, Issue 1, 2014, Pages 184-187

  Wolf, Jana ^a   Passmore, Lori A ^a  

^a MRC LABORATORY OF MOLECULAR BIOLOGY   (United Kingdom)

Author keywords

Exonuclease; Gene expression; MRNA; MRNA decay; Poly(A) tail

Indexed keywords

CHEMOKINE RECEPTOR CCR4; EXONUCLEASE; INITIATION FACTOR 4F; MESSENGER RNA; POLYADENYLIC ACID; PROTEIN PAN2; PROTEIN PAN3; UNCLASSIFIED DRUG;

3' UNTRANSLATED REGION; ADENYLATION; ARTICLE; CARBOXY TERMINAL SEQUENCE; COMPLEX FORMATION; CYTOPLASM; DEADENYLATION; EXOSOME; GENE EXPRESSION; HUMAN; MESSENGER RNA SYNTHESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; RNA DEGRADATION; RNA PROCESSING; RNA STABILITY; RNA STRUCTURE; STRESS; TRANSLATION INITIATION;

ANIMALS; CARRIER PROTEINS; EXORIBONUCLEASES; GENE EXPRESSION REGULATION; HUMANS; POLYADENYLATION; RNA STABILITY; RNA, MESSENGER;

EID: 84893213989     PISSN: 03005127     EISSN: 14708752     Source Type: Journal    
DOI: 10.1042/BST20130211     Document Type: Article

References (50)

1. Zhao, J., Hyman, L. and Moore, C. (1999) Formation of mRNA 3′ ends in eukaryotes: mechanism, regulation, and interrelationships with other steps in mRNA synthesis. Microbiol. Mol. Biol. Rev. 63, 405-445
2. Garneau, N.L., Wilusz, J. and Wilusz, C.J. (2007) The highways and byways of mRNA decay. Nat. Rev. Mol. Cell Biol. 8, 113-126
3. Wiederhold, K. and Passmore, L.A. (2010) Cytoplasmic deadenylation: regulation of mRNA fate. Biochem. Soc. Trans. 38, 1531-1536
4. Sachs, A.B., Davis, R.W. and Kornberg, R.D. (1987) A single domain of yeast poly(A)-binding protein is necessary and sufficient for RNA binding and cell viability. Mol. Cell. Biol. 7, 3268-3276
5. Sachs, A.B. and Davis, R.W. (1989) The poly(A) binding protein is required for poly(A) shortening and 60S ribosomal subunit-dependent translation initiation. Cell 58, 857-867
6. Tarun, S.Z. and Sachs, A.B. (1996) Association of the yeast poly(A) tail binding protein with translation initiation factor eIF-4G. EMBO J. 15, 7168-7177
7. Kapp, L.D. and Lorsch, J.R. (2004) The molecular mechanics of eukaryotic translation. Annu. Rev. Biochem. 73, 657-704
8. Novoa, I., Gallego, J., Ferreira, P.G. and Mendez, R. (2010) Mitotic cell-cycle progression is regulated by CPEB1 and CPEB4-dependent translational control. Nat. Cell Biol. 12, 447-456
9. Beilharz, T.H. and Preiss, T. (2007) Widespread use of poly(A) tail length control to accentuate expression of the yeast transcriptome. RNA 13, 982-997
10. Sachs, A.B. and Deardorff, J.A. (1992) Translation initiation requires the PAB-dependent poly(A) ribonuclease in yeast. Cell 70, 961-973
11. Boeck, R., Tarun, S., Rieger, M., Deardorff, J.A., Müller-Auer, S. and Sachs, A.B. (1996) The yeast Pan2 protein is required for poly(A)-binding protein-stimulated poly(A)-nuclease activity. J. Biol. Chem. 271, 432-438
12. Brown, C.E., Tarun, S.Z., Boeck, R. and Sachs, A.B. (1996) PAN3 encodes a subunit of the Pab1p-dependent poly(A) nuclease in Saccharomyces cerevisiae. Mol. Cell. Biol. 16, 5744-5753
13. Moser, M.J., Holley, W.R., Chatterjee, A. and Mian, I.S. (1997) The proofreading domain of Escherichia coli DNA polymerase I and other DNA and/or RNA exonuclease domains. Nucleic Acids Res. 25, 5110-5118
14. Zuo, Y. and Deutscher, M.P. (2001) Exoribonuclease superfamilies: structural analysis and phylogenetic distribution. Nucleic Acids Res. 29, 1017-1026
15. Quesada, V., Díaz-Perales, A., Gutiérrez-Fernández, A., Garabaya, C., Cal, S. and López-Otín, C. (2004) Cloning and enzymatic analysis of 22 novel human ubiquitin-specific proteases. Biochem. Biophys. Res. Commun. 314, 54-62
16. Mangus, D.A., Evans, M.C., Agrin, N.S., Smith, M., Gongidi, P. and Jacobson, A. (2004) Positive and negative regulation of poly(A) nuclease. Mol. Cell. Biol. 24, 5521-5533
17. Uchida, N., Hoshino, S.-I. and Katada, T. (2004) Identification of a human cytoplasmic poly(A) nuclease complex stimulated by poly(A)-binding protein. J. Biol. Chem. 279, 1383-1391
18. Siddiqui, N., Mangus, D.A., Chang, T.-C., Palermino, J.-M., Shyu, A.-B. and Gehring, K. (2007) Poly(A) nuclease interacts with the C-terminal domain of polyadenylate-binding protein domain from poly(A)-binding protein. J. Biol. Chem. 282, 25067-25075
19. Lowell, J.E., Rudner, D.Z. and Sachs, A.B. (1992) 3′-UTR-dependent deadenylation by the yeast poly(A) nuclease. Genes Dev. 6, 2088-2099
20. Baer, B.W. and Kornberg, R.D. (1980) Repeating structure of cytoplasmic poly(A)-ribonucleoprotein. Proc. Natl. Acad. Sci. U.S.A. 77, 1890-1892
21. Brown, C.E. and Sachs, A.B. (1998) Poly(A) tail length control in Saccharomyces cerevisiae occurs by message-specific deadenylation. Mol. Cell. Biol. 18, 6548-6559
22. Schmid, M., Poulsen, M.B., Olszewski, P., Pelechano, V., Saguez, C., Gupta, I., Steinmetz, L.M., Moore, C. and Jensen, T.H. (2012) Rrp6p controls mRNA poly(A) tail length and its decoration with poly(A) binding proteins. Mol. Cell 47, 267-280
23. Dunn, E.F., Hammell, C.M., Hodge, C.A. and Cole, C.N. (2005) Yeast poly(A)-binding protein, Pab1, and PAN, a poly(A) nuclease complex recruited by Pab1, connect mRNA biogenesis to export. Genes Dev. 19, 90-103
24. Dheur, S., Nykamp, K.R., Viphakone, N., Swanson, M.S. and Minvielle-Sebastia, L. (2005) Yeast mRNA poly(A) tail length control can be reconstituted in vitro in the absence of Pab1p-dependent poly(A) nuclease activity. J. Biol. Chem. 280, 24532-24538
25. Decker, C.J. and Parker, R. (1993) A turnover pathway for both stable and unstable mRNAs in yeast: evidence for a requirement for deadenylation. Genes Dev. 7, 1632-1643
26. Parker, R. and Song, H. (2004) The enzymes and control of eukaryotic mRNA turnover. Nat. Struct. Mol. Biol. 11, 121-127
27. Zheng, D., Ezzeddine, N., Chen, C.-Y.A., Zhu, W., He, X. and Shyu, A.-B. (2008) Deadenylation is prerequisite for P-body formation and mRNA decay in mammalian cells. J. Cell Biol. 182, 89-101
28. Tucker, M., Valencia-Sanchez, M.A., Staples, R.R., Chen, J., Denis, C.L. and Parker, R. (2001) The transcription factor associated Ccr4 and Caf1 proteins are components of the major cytoplasmic mRNA deadenylase in Saccharomyces cerevisiae. Cell 104, 377-386
29. Yamashita, A., Chang, T.-C., Yamashita, Y., Zhu, W., Zhong, Z., Chen, C.-Y.A. and Shyu, A.-B. (2005) Concerted action of poly(A) nucleases and decapping enzyme in mammalian mRNA turnover. Nat. Struct. Mol. Biol. 12, 1054-1063
30. Bönisch, C., Temme, C., Moritz, B. and Wahle, E. (2007) Degradation of hsp70 and other mRNAs in Drosophila via the 5′-3′ pathway and its regulation by heat shock. J. Biol. Chem. 282, 21818-21828
31. Fadda, A., Färber, V., Droll, D. and Clayton, C. (2013) The roles of 3′-exoribonucleases and the exosome in trypanosome mRNA degradation. RNA 19, 937-947
32. Weill, L., Belloc, E., Bava, F.-A. and Mendez, R. (2012) Translational control by changes in poly(A) tail length: recycling mRNAs. Nat. Struct. Mol. Biol. 19, 577-585
33. Huang, K.-L., Chadee, A.B., Chen, C.-Y.A., Zhang, Y. and Shyu, A.-B. (2013) Phosphorylation at intrinsically disordered regions of PAM2 motif-containing proteins modulates their interactions with PABPC1 and influences mRNA fate. RNA 19, 295-305
34. Wahle, E. and Winkler, G.S. (2013) RNA decay machines: deadenylation by the Ccr4-Not and Pan2-Pan3 complexes. Biochim. Biophys. Acta 1829, 561-570
35. Lee, D., Ohn, T., Chiang, Y.-C., Quigley, G., Yao, G., Liu, Y. and Denis, C.L. (2010) PUF3 acceleration of deadenylation in vivo can operate independently of CCR4 activity, possibly involving effects on the PAB1-mRNP structure. J. Mol. Biol. 399, 562-575
36. Fabian, M.R., Cieplak, M.K., Frank, F., Morita, M., Green, J., Srikumar, T., Nagar, B., Yamamoto, T., Raught, B., Duchaine, T.F. et al. (2011) miRNA-mediated deadenylation is orchestrated by GW182 through two conserved motifs that interact with CCR4-NOT. Nat. Struct. Mol. Biol. 18, 1211-1217
37. Braun, J.E., Huntzinger, E., Fauser, M. and Izaurralde, E. (2011) GW182 proteins directly recruit cytoplasmic deadenylase complexes to miRNA targets. Mol. Cell 44, 120-133
38. Chekulaeva, M., Mathys, H., Zipprich, J.T., Attig, J., Colic, M., Parker, R. and Filipowicz, W. (2011) miRNA repression involves GW182-mediated recruitment of CCR4-NOT through conserved W-containing motifs. Nat. Struct. Mol. Biol. 18, 1218-1226
39. Kuzuoglu-Öztürk, D., Huntzinger, E., Schmidt, S. and Izaurralde, E. (2012) The Caenorhabditis elegans GW182 protein AIN-1 interacts with PAB-1 and subunits of the PAN2-PAN3 and CCR4-NOT deadenylase complexes. Nucleic Acids Res. 40, 5651-5665
40. Chen, C.-Y.A., Zheng, D., Xia, Z. and Shyu, A.-B. (2009) Ago-TNRC6 triggers microRNA-mediated decay by promoting two deadenylation steps. Nat. Struct. Mol. Biol. 16, 1160-1166
41. Cooke, A., Prigge, A. and Wickens, M. (2010) Translational repression by deadenylases. J. Biol. Chem. 285, 28506-28513
42. Meijer, H.A., Kong, Y.W., Lu, W.T., Wilczynska, A., Spriggs, R.V., Robinson, S.W., Godfrey, J.D., Willis, A.E. and Bushell, M. (2013) Translational repression and eIF4A2 activity are critical for microRNA-mediated gene regulation. Science 340, 82-85
43. Zekri, L., Kuzuoglu-Öztürk, D. and Izaurralde, E. (2013) GW182 proteins cause PABP dissociation from silenced miRNA targets in the absence of deadenylation. EMBO J. 32, 1052-1065
44. Hammet, A., Pike, B.L. and Heierhorst, J. (2002) Posttranscriptional regulation of the RAD5 DNA repair gene by the Dun1 kinase and the Pan2-Pan3 poly(A)-nuclease complex contributes to survival of replication blocks. J. Biol. Chem. 277, 22469-22474
45. Hilgers, V., Teixeira, D. and Parker, R. (2006) Translation-independent inhibition of mRNA deadenylation during stress in Saccharomyces cerevisiae. RNA 12, 1835-1845
46. Gowrishankar, G., Winzen, R., Dittrich-Breiholz, O., Redich, N., Kracht, M. and Holtmann, H. (2006) Inhibition of mRNA deadenylation and degradation by different types of cell stress. Biol. Chem. 387, 323-327
47. Caponigro, G. and Parker, R. (1995) Multiple functions for the poly(A)-binding protein in mRNA decapping and deadenylation in yeast. Genes Dev. 9, 2421-2432
48. Dori-Bachash, M., Shema, E. and Tirosh, I. (2011) Coupled evolution of transcription and mRNA degradation. PLoS Biol. 9, e1001106
49. Sun, M., Schwalb, B., Schulz, D., Pirkl, N., Etzold, S., Larivière, L., Maier, K.C., Seizl, M., Tresch, A. and Cramer, P. (2012) Comparative dynamic transcriptome analysis (cDTA) reveals mutual feedback between mRNA synthesis and degradation. Genome Res. 22, 1350-1359
50. Christie, M., Boland, A., Huntzinger, E., Weichenrieder, O. and Izaurralde, E. (2013) Structure of the PAN3 pseudokinase reveals the basis for interactions with the PAN2 deadenylase and the GW182 proteins. Mol. Cell 51, 360-373