Phosphorylation at intrinsically disordered regions of PAM2 motif-containing proteins modulates their interactions with PABPC1 and influences mRNA fate

RNA

Volumn 19, Issue 3, 2013, Pages 295-305

  Huang, Kai Lieh ^a   Chadee, Amanda B ^a,b   Chen, Chyi Ying A ^a   Zhang, Yueqiang ^a   Shyu, Ann Bin ^a  

^a UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

^b LONE STAR COLLEGE   (United States)

Author keywords

Deadenylation; GW182; Intrinsically disordered region; MiRNA function; MRNA turnover; PABP; PAM2 motif; Protein phosphorylation; Translation

Indexed keywords

CYTOPLASMIC POLYADENYLATION ELEMENT BINDING PROTEIN; CYTOPLASMIC POLYADENYLATION ELEMENT BINDING PROTEIN C1; MESSENGER RNA; NUCLEIC ACID BINDING PROTEIN; NUCLEIC ACID BINDING PROTEIN PAN3; NUCLEIC ACID BINDING PROTEIN TNRC6C; NUCLEIC ACID BINDING PROTEIN TOB2; SERINE; THREONINE; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; GENE SILENCING; HUMAN; HUMAN CELL; INTRINSICALLY DISORDERED REGION; NONHUMAN; PRIORITY JOURNAL; PROTEIN INTERACTION; PROTEIN MOTIF; PROTEIN PHOSPHORYLATION; REGULATORY MECHANISM; TURNOVER TIME; WESTERN BLOTTING;

AMINO ACID MOTIFS; AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; CELLS, CULTURED; CYTOPLASM; HUMANS; MICE; NIH 3T3 CELLS; PHOSPHORYLATION; POLY A; POLY(A)-BINDING PROTEIN I; RNA, MESSENGER; SERINE; THREONINE; TRANSFECTION;

EID: 84874312261     PISSN: 13558382     EISSN: 14699001     Source Type: Journal    
DOI: 10.1261/rna.037317.112     Document Type: Article

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