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Volumn 2014, Issue , 2014, Pages

Anticancer and antitumor potential of fucoidan and fucoxanthin, two main metabolites isolated from brown algae

Author keywords

[No Author keywords available]

Indexed keywords

ALGAL EXTRACT; CAROTENOID; FLUOROURACIL; FUCOIDIN; FUCOXANTHIN; POLYSACCHARIDE SULFATE; VASCULOTROPIN 165; ANTINEOPLASTIC AGENT; POLYSACCHARIDE; XANTHOPHYLL;

EID: 84893192820     PISSN: None     EISSN: 1537744X     Source Type: Journal    
DOI: 10.1155/2014/768323     Document Type: Review
Times cited : (143)

References (60)
  • 1
    • 80053244339 scopus 로고    scopus 로고
    • Nigerian foodstuffs with prostate cancer chemopreventive polyphenols
    • supplement 2, article S9 2-s2.0-80053244339 10.1186/1750-9378-6-S2-S9
    • Atawodi S., Nigerian foodstuffs with prostate cancer chemopreventive polyphenols. Infectious Agents and Cancer 2011 6 supplement 2, article S9 2-s2.0-80053244339 10.1186/1750-9378-6-S2-S9
    • (2011) Infectious Agents and Cancer , vol.6
    • Atawodi, S.1
  • 2
    • 59449102796 scopus 로고    scopus 로고
    • Impact, mechanisms, and novel chemotherapy strategies for overcoming resistance to anthracyclines and taxanes in metastatic breast cancer
    • 2-s2.0-59449102796 10.1007/s10549-008-0005-6
    • Perez E. A., Impact, mechanisms, and novel chemotherapy strategies for overcoming resistance to anthracyclines and taxanes in metastatic breast cancer. Breast Cancer Research and Treatment 2009 114 2 195 201 2-s2.0-59449102796 10.1007/s10549-008-0005-6
    • (2009) Breast Cancer Research and Treatment , vol.114 , Issue.2 , pp. 195-201
    • Perez, E.A.1
  • 3
    • 84861854118 scopus 로고    scopus 로고
    • A killer promoting survival: P53 as a selective means to avoid side effects of chemotherapy
    • 10.4161/cc.20698
    • Kranz D., Dobbelstein M., A killer promoting survival: p53 as a selective means to avoid side effects of chemotherapy. Cell Cycle 2012 11 11 2053 2054 10.4161/cc.20698
    • (2012) Cell Cycle , vol.11 , Issue.11 , pp. 2053-2054
    • Kranz, D.1    Dobbelstein, M.2
  • 4
    • 34250308322 scopus 로고    scopus 로고
    • Apoptosis: A review of programmed cell death
    • DOI 10.1080/01926230701320337, PII 779478428
    • Elmore S., Apoptosis: a review of programmed cell death. Toxicologic Pathology 2007 35 4 495 516 2-s2.0-34250308322 10.1080/01926230701320337 (Pubitemid 46911891)
    • (2007) Toxicologic Pathology , vol.35 , Issue.4 , pp. 495-516
    • Elmore, S.1
  • 5
    • 61849148824 scopus 로고    scopus 로고
    • Natural products and drug discovery: Can thousands of years of ancient medical knowledge lead us to new and powerful drug combinations in the fight against cancer and dementia?
    • 2-s2.0-61849148824 10.1038/embor.2009.12
    • Ji H. F., Li X. J., Zhang H. Y., Natural products and drug discovery: can thousands of years of ancient medical knowledge lead us to new and powerful drug combinations in the fight against cancer and dementia? EMBO Reports 2009 10 3 194 200 2-s2.0-61849148824 10.1038/embor.2009.12
    • (2009) EMBO Reports , vol.10 , Issue.3 , pp. 194-200
    • Ji, H.F.1    Li, X.J.2    Zhang, H.Y.3
  • 6
    • 78751581464 scopus 로고    scopus 로고
    • Anti-proliferative activity of phlorotannin extracts from brown algae Laminaria japonica Aresch
    • 2-s2.0-78751581464 10.1007/s00343-010-9054-x
    • Yang H., Zeng M., Dong S., Liu Z., Li R., Anti-proliferative activity of phlorotannin extracts from brown algae Laminaria japonica Aresch. Chinese Journal of Oceanology and Limnology 2010 28 1 122 130 2-s2.0-78751581464 10.1007/s00343-010-9054-x
    • (2010) Chinese Journal of Oceanology and Limnology , vol.28 , Issue.1 , pp. 122-130
    • Yang, H.1    Zeng, M.2    Dong, S.3    Liu, Z.4    Li, R.5
  • 7
    • 80052267548 scopus 로고    scopus 로고
    • Biological activities and health benefit effects of natural pigments derived from marine algae
    • 2-s2.0-80052267548 10.1016/j.jff.2011.07.001
    • Pangestuti R., Kim S. K., Biological activities and health benefit effects of natural pigments derived from marine algae. Journal of Functional Foods 2011 3 4 255 266 2-s2.0-80052267548 10.1016/j.jff.2011.07.001
    • (2011) Journal of Functional Foods , vol.3 , Issue.4 , pp. 255-266
    • Pangestuti, R.1    Kim, S.K.2
  • 8
    • 0021814973 scopus 로고
    • Effect of dietary seaweed preparations on 1,2-dimethylhydrazine-induced intestinal carcinogenesis in rats
    • DOI 10.1016/0304-3835(85)90047-3
    • Yamamoto I., Maruyama H., Effect of dietary seaweed preparations on 1,2-dimethylhydrazine-induced intestinal carcinogenesis in rats. Cancer Letters 1985 26 3 241 251 2-s2.0-0021814973 (Pubitemid 15032602)
    • (1985) Cancer Letters , vol.26 , Issue.3 , pp. 241-251
    • Yamamoto, I.1    Maruyama, H.2
  • 9
    • 0023183450 scopus 로고
    • The effect of dietary seaweeds on 7,12-dimethyl-benz[a]anthracene-induced mammary tumorigenesis in rats
    • DOI 10.1016/0304-3835(87)90033-4
    • Yamamoto I., Maruyama H., Moriguchi M., The effect of dietary seaweeds on 7,12-dimethyl-benz[a]anthracene-induced mammary tumorigenesis in rats. Cancer Letters 1987 35 2 109 118 2-s2.0-0023183450 (Pubitemid 17115946)
    • (1987) Cancer Letters , vol.35 , Issue.2 , pp. 109-118
    • Yamamoto, I.1    Maruyama, H.2    Moriguchi, M.3
  • 10
    • 0028075451 scopus 로고
    • Effects in vitro of sulfated polysaccharide from Schizymenia dubyi (Rhodophyta, Gigartinales) on a non-small-cell bronchopulmonary carcinoma line (NSCLC-N6)
    • DOI 10.1016/0304-3835(94)90243-7
    • Bourgougnon N., Roussakis C., Kornprobst J. M., Lahaye M., Effects in vitro of sulfated polysaccharide from Schizymenia dubyi (Rhodophyta, Gigartinales) on a non-small-cell bronchopulmonary carcinoma line (NSCLC-N6). Cancer Letters 1994 85 1 87 92 2-s2.0-0028075451 10.1016/0304-3835(94)90243-7 (Pubitemid 24280167)
    • (1994) Cancer Letters , vol.85 , Issue.1 , pp. 87-92
    • Bourgougnon, N.1    Roussakis, C.2    Kornprobst, J.-M.3    Lahaye, M.4
  • 11
    • 0038219974 scopus 로고    scopus 로고
    • Marine pharmacology in 2000: Antitumor and cytotoxic compounds
    • DOI 10.1002/ijc.11080
    • Mayer A. M. S., Gustafson K. R., Marine pharmacology in 2000: antitumor and cytotoxic compounds. International Journal of Cancer 2003 105 3 291 299 2-s2.0-0038219974 10.1002/ijc.11080 (Pubitemid 36570039)
    • (2003) International Journal of Cancer , vol.105 , Issue.3 , pp. 291-299
    • Mayer, A.M.S.1    Gustafson, K.R.2
  • 12
    • 77953580322 scopus 로고    scopus 로고
    • Protective effect of amphiroa dilatata on ROS induced oxidative damage and MMP expressions in HT1080 cells
    • 2-s2.0-77953580322 10.1007/s12257-009-0052-9
    • Khan S. B., Kong C. S., Kim J. A., Kim S. K., Protective effect of amphiroa dilatata on ROS induced oxidative damage and MMP expressions in HT1080 cells. Biotechnology and Bioprocess Engineering 2010 15 1 191 198 2-s2.0-77953580322 10.1007/s12257-009-0052-9
    • (2010) Biotechnology and Bioprocess Engineering , vol.15 , Issue.1 , pp. 191-198
    • Khan, S.B.1    Kong, C.S.2    Kim, J.A.3    Kim, S.K.4
  • 13
    • 0842304213 scopus 로고    scopus 로고
    • Biotransformation of fucoxanthinol into amarouciaxanthin a in mice and HepG2 cells: Formation and cytotoxicity of fucoxanthin metabolites
    • DOI 10.1124/dmd.32.2.205
    • Asai A., Sugawara T., Ono H., Nagao A., Biotransformation of fucoxanthinol into amarouciaxanthin a in mice and HepG2 cells: formation and cytotoxicity of fucoxanthin metabolites. Drug Metabolism and Disposition 2004 32 2 205 211 2-s2.0-0842304213 10.1124/dmd.32.2.205 (Pubitemid 38176937)
    • (2004) Drug Metabolism and Disposition , vol.32 , Issue.2 , pp. 205-211
    • Asai, A.1    Sugawara, T.2    Ono, H.3    Nagao, A.4
  • 14
    • 33749241096 scopus 로고    scopus 로고
    • Porphyran induces apoptosis related signal pathway in AGS gastric cancer cell lines
    • DOI 10.1016/j.lfs.2006.06.031, PII S002432050600498X
    • Kwon M. J., Nam T. J., Porphyran induces apoptosis related signal pathway in AGS gastric cancer cell lines. Life Sciences 2006 79 20 1956 1962 2-s2.0-33749241096 10.1016/j.lfs.2006.06.031 (Pubitemid 44485121)
    • (2006) Life Sciences , vol.79 , Issue.20 , pp. 1956-1962
    • Kwon, M.-J.1    Nam, T.-J.2
  • 15
    • 67349101223 scopus 로고    scopus 로고
    • Antioxidant and antitumoural activities of some Phaeophyta from Brittany coasts
    • 2-s2.0-67349101223 10.1016/j.foodchem.2009.03.025
    • Zubia M., Fabre M. S., Kerjean V., Lann K. L., Stiger-Pouvreau V., Fauchon M., Deslandes E., Antioxidant and antitumoural activities of some Phaeophyta from Brittany coasts. Food Chemistry 2009 116 3 693 701 2-s2.0-67349101223 10.1016/j.foodchem.2009.03.025
    • (2009) Food Chemistry , vol.116 , Issue.3 , pp. 693-701
    • Zubia, M.1    Fabre, M.S.2    Kerjean, V.3    Lann, K.L.4    Stiger-Pouvreau, V.5    Fauchon, M.6    Deslandes, E.7
  • 16
    • 77954880512 scopus 로고    scopus 로고
    • Assessment of in vitro antitumoral and antimicrobial activities of marine algae harvested from the eastern Mediterranean sea
    • 2-s2.0-77954880512
    • Taskin E., Caki Z., Ozturk M., Taskin E., Assessment of in vitro antitumoral and antimicrobial activities of marine algae harvested from the eastern Mediterranean sea. African Journal of Biotechnology 2010 9 27 4272 4277 2-s2.0-77954880512
    • (2010) African Journal of Biotechnology , vol.9 , Issue.27 , pp. 4272-4277
    • Taskin, E.1    Caki, Z.2    Ozturk, M.3    Taskin, E.4
  • 17
    • 33744929600 scopus 로고    scopus 로고
    • Antiproliferative and antioxidant properties of an enzymatic hydrolysate from brown alga, Ecklonia cava
    • DOI 10.1016/j.fct.2006.01.011, PII S0278691506000068
    • Athukorala Y., Kim K. N., Jeon Y. J., Antiproliferative and antioxidant properties of an enzymatic hydrolysate from brown alga, Ecklonia cava. Food and Chemical Toxicology 2006 44 7 1065 1074 2-s2.0-33744929600 10.1016/j.fct.2006. 01.011 (Pubitemid 43850075)
    • (2006) Food and Chemical Toxicology , vol.44 , Issue.7 , pp. 1065-1074
    • Athukorala, Y.1    Kim, K.-N.2    Jeon, Y.-J.3
  • 21
    • 4444379223 scopus 로고    scopus 로고
    • Sulfated seaweed polysaccharides as antiviral agents
    • Damonte E. B., Matulewicz M. C., Cerezo A. S., Sulfated seaweed polysaccharides as antiviral agents. Current Medicinal Chemistry 2004 11 18 2399 2419 2-s2.0-4444379223 (Pubitemid 39172357)
    • (2004) Current Medicinal Chemistry , vol.11 , Issue.18 , pp. 2399-2419
    • Damonte, E.B.1    Matulewicz, M.C.2    Cerezo, A.S.3
  • 23
    • 0035961371 scopus 로고    scopus 로고
    • A disaccharide repeat unit is the major structure in fucoidans from two species of brown algae
    • DOI 10.1016/S0008-6215(00)00314-1, PII S0008621500003141
    • Chevolot L., Mulloy B., Ratiskol J., Foucault A., Colliec-Jouault S., A disaccharide repeat unit is the major structure in fucoidans from two species of brown algae. Carbohydrate Research 2001 330 4 529 535 2-s2.0-0035961371 10.1016/S0008-6215(00)00314-1 (Pubitemid 32206395)
    • (2001) Carbohydrate Research , vol.330 , Issue.4 , pp. 529-535
    • Chevolot, L.1    Mulloy, B.2    Ratiskol, J.3    Foucault, A.4    Colliec-Jouault, S.5
  • 24
    • 34250796744 scopus 로고    scopus 로고
    • Anti-proliferative activity of oversulfated fucoidan from commercially cultured Cladosiphon okamuranus TOKIDA in U937 cells
    • DOI 10.1016/j.ijbiomac.2007.02.010, PII S0141813007000761
    • Teruya T., Konishi T., Uechi S., Tamaki H., Tako M., Anti-proliferative activity of oversulfated fucoidan from commercially cultured Cladosiphon okamuranus TOKIDA in U937 cells. International Journal of Biological Macromolecules 2007 41 3 221 226 2-s2.0-34250796744 10.1016/j.ijbiomac.2007.02. 010 (Pubitemid 46990525)
    • (2007) International Journal of Biological Macromolecules , vol.41 , Issue.3 , pp. 221-226
    • Teruya, T.1    Konishi, T.2    Uechi, S.3    Tamaki, H.4    Tako, M.5
  • 25
    • 0021228256 scopus 로고
    • Antitumor effect of seaweeds. IV. Enhancement of antitumor activity by sulfation of a crude fucoidan fraction from sargassum kjellmanianum
    • Yamamoto I., Takahashi M., Suzuki T., Antitumor effect of seaweeds. IV. Enhancement of antitumor activity by sulfation of a crude fucoidan fraction from sargassum kjellmanianum. Japanese Journal of Experimental Medicine 1984 54 4 143 151 2-s2.0-0021228256 (Pubitemid 14010593)
    • (1984) Japanese Journal of Experimental Medicine , vol.54 , Issue.4 , pp. 143-151
    • Yamamoto, I.1    Takahashi, M.2    Suzuki, T.3
  • 26
    • 0023132816 scopus 로고
    • Analysis of the inhibition of tumour metastasis by sulphated polysaccharides
    • Coombe D. R., Parish C. R., Ramshaw I. A., Snowden J. M., Analysis of the inhibition of tumour metastasis by sulphated polysaccharides. International Journal of Cancer 1987 39 1 82 88 2-s2.0-0023132816 (Pubitemid 17233832)
    • (1987) International Journal of Cancer , vol.39 , Issue.1 , pp. 82-88
    • Coombe, D.R.1    Parish, C.R.2    Ramshaw, I.A.3    Snowden, J.M.4
  • 27
    • 0029278080 scopus 로고
    • Antitumor active fucoidan from the brown seaweed, umitoranoo (Sargassum thunbergii)
    • 2-s2.0-0029278080
    • Zhuang Cun Z. C., Itoh H., Mizuno T., Ito H., Antitumor active fucoidan from the brown seaweed, umitoranoo (Sargassum thunbergii). Bioscience, Biotechnology and Biochemistry 1995 59 4 563 567 2-s2.0-0029278080
    • (1995) Bioscience, Biotechnology and Biochemistry , vol.59 , Issue.4 , pp. 563-567
    • Zhuang Cun, Z.C.1    Itoh, H.2    Mizuno, T.3    Ito, H.4
  • 28
    • 0037437728 scopus 로고    scopus 로고
    • Oversulfation of fucoidan enhances its anti-angiogenic and antitumor activities
    • DOI 10.1016/S0006-2952(02)01478-8, PII S0006295202014788
    • Koyanagi S., Tanigawa N., Nakagawa H., Soeda S., Shimeno H., Oversulfation of fucoidan enhances its anti-angiogenic and antitumor activities. Biochemical Pharmacology 2003 65 2 173 179 2-s2.0-0037437728 10.1016/S0006-2952(02)01478-8 (Pubitemid 36015820)
    • (2003) Biochemical Pharmacology , vol.65 , Issue.2 , pp. 173-179
    • Koyanagi, S.1    Tanigawa, N.2    Nakagawa, H.3    Soeda, S.4    Shimeno, H.5
  • 29
    • 28944446844 scopus 로고    scopus 로고
    • Enzyme-digested fucoidan extracts derived from seaweed Mozuku of Cladosiphon novae-caledoniae kylin inhibit invasion and angiogenesis of tumor cells
    • DOI 10.1007/s10616-005-3761-8
    • Ye J., Li Y., Teruya K., Katakura Y., Ichikawa A., Eto H., Hosoi M., Hosoi M., Nishimoto S., Shirahata S., Enzyme-digested fucoidan extracts derived from seaweed Mozuku of Cladosiphon novae-caledoniae kylin inhibit invasion and angiogenesis of tumor cells. Cytotechnology 2005 47 1 3 117 126 2-s2.0-28944446844 10.1007/s10616-005-3761-8 (Pubitemid 41784672)
    • (2005) Cytotechnology , vol.47 , Issue.1-3 , pp. 117-126
    • Ye, J.1    Li, Y.2    Teruya, K.3    Katakura, Y.4    Ichikawa, A.5    Eto, H.6    Hosoi, M.7    Hosoi, M.8    Nishimoto, S.9    Shirahata, S.10
  • 30
    • 0027751896 scopus 로고
    • Antitumor activity and immunological properties of marine algal polysaccharides, especially fucoidan, prepared from Sargassum thunbergii of phaeophyceae
    • Itoh H., Noda H., Amano H., Zhuaug C., Mizuno T., Ito H., Antitumor activity and immunological properties of marine algal polysaccharides, especially fucoidan, prepared from Sargassum thunbergii of phaeophyceae. Anticancer Research 1993 13 6 2045 2052 2-s2.0-0027751896 (Pubitemid 24036324)
    • (1993) Anticancer Research , vol.13 , Issue.6 A , pp. 2045-2052
    • Itoh, H.1    Noda, H.2    Amano, H.3    Zhuaug, C.4    Mizuno, T.5    Ito, H.6
  • 31
    • 0041621601 scopus 로고    scopus 로고
    • Antitumor activity and immune response of Mekabu fucoidan extracted from Sporophyll of Undaria pinnatifida
    • Maruyama H., Tamauchi H., Hashimoto M., Nakano T., Antitumor activity and immune response of Mekabu fucoidan extracted from Sporophyll of Undaria pinnatifida. In Vivo 2003 17 3 245 249 2-s2.0-0041621601 (Pubitemid 36958113)
    • (2003) Vivo , vol.17 , Issue.3 , pp. 245-249
    • Maruyama, H.1    Tamauchi, H.2    Hashimoto, M.3    Nakano, T.4
  • 34
    • 11144297712 scopus 로고    scopus 로고
    • Fucoidan induces apoptosis of human HS-Sultan cells accompanied by activation of caspase-3 and down-regulation of ERK pathways
    • DOI 10.1002/ajh.20182
    • Aisa Y., Miyakawa Y., Nakazato T., Shibata H., Saito K., Ikeda Y., Kizaki M., Fucoidan induces apoptosis of human HS-Sultan cells accompanied by activation of caspase-3 and down-regulation of ERK pathways. American Journal of Hematology 2005 78 1 7 14 2-s2.0-11144297712 10.1002/ajh.20182 (Pubitemid 40023740)
    • (2005) American Journal of Hematology , vol.78 , Issue.1 , pp. 7-14
    • Aisa, Y.1    Miyakawa, Y.2    Nakazato, T.3    Shibata, H.4    Saito, K.5    Ikeda, Y.6    Kizaki, M.7
  • 36
    • 70349319640 scopus 로고    scopus 로고
    • Fucoidan induces apoptosis through activation of caspase-8 on human breast cancer MCF-7 cells
    • 2-s2.0-70349319640 10.1021/jf9010406
    • Yamasaki-Miyamoto Y., Yamasaki M., Tachibana H., Yamada K., Fucoidan induces apoptosis through activation of caspase-8 on human breast cancer MCF-7 cells. Journal of Agricultural and Food Chemistry 2009 57 18 8677 8682 2-s2.0-70349319640 10.1021/jf9010406
    • (2009) Journal of Agricultural and Food Chemistry , vol.57 , Issue.18 , pp. 8677-8682
    • Yamasaki-Miyamoto, Y.1    Yamasaki, M.2    Tachibana, H.3    Yamada, K.4
  • 37
    • 0842265914 scopus 로고    scopus 로고
    • A highly regular fraction of a fucoidan from the brown seaweed Fucus distichus L
    • DOI 10.1016/j.carres.2003.10.028
    • Bilan M. I., Grachev A. A., Ustuzhanina N. E., Shashkov A. S., Nifantiev N. E., Usov A. I., A highly regular fraction of a fucoidan from the brown seaweed Fucus distichus L. Carbohydrate Research 2004 339 3 511 517 2-s2.0-0842265914 10.1016/j.carres.2003.10.028 (Pubitemid 38167650)
    • (2004) Carbohydrate Research , vol.339 , Issue.3 , pp. 511-517
    • Bilan, M.I.1    Grachev, A.A.2    Ustuzhanina, N.E.3    Shashkov, A.S.4    Nifantiev, N.E.5    Usov, A.I.6
  • 38
    • 77955766528 scopus 로고    scopus 로고
    • Fucoidan present in brown algae induces apoptosis of human colon cancer cells
    • article 96 2-s2.0-77955766528 10.1186/1471-230X-10-96
    • Kim E. J., Park S. Y., Lee J. Y., Park J. H. Y., Fucoidan present in brown algae induces apoptosis of human colon cancer cells. BMC Gastroenterology 2010 10 article 96 2-s2.0-77955766528 10.1186/1471-230X-10-96
    • (2010) BMC Gastroenterology , vol.10
    • Kim, E.J.1    Park, S.Y.2    Lee, J.Y.3    Park, J.H.Y.4
  • 40
    • 77950863237 scopus 로고    scopus 로고
    • Structure and antitumour activity of fucoidan isolated from sporophyll of Korean brown seaweed Undaria pinnatifida
    • 2-s2.0-77950863237 10.1016/j.carbpol.2010.01.052
    • Synytsya A., Kim W. J., Kim S. M., Pohl R., Synytsya A., Kvasnička F., Čopíková J., Il Park Y., Structure and antitumour activity of fucoidan isolated from sporophyll of Korean brown seaweed Undaria pinnatifida. Carbohydrate Polymers 2010 81 1 41 48 2-s2.0-77950863237 10.1016/j.carbpol.2010.01.052
    • (2010) Carbohydrate Polymers , vol.81 , Issue.1 , pp. 41-48
    • Synytsya, A.1    Kim, W.J.2    Kim, S.M.3    Pohl, R.4    Synytsya, A.5    Kvasnička, F.6    Čopíková, J.7    Il Park, Y.8
  • 42
    • 36749088994 scopus 로고    scopus 로고
    • Sensitization of human malignant lymphoid cells to etoposide by fucoidan, a brown seaweed polysaccharide
    • Philchenkov A., Zavelevich M., Imbs T., Zvyagintseva T., Zaporozhets T., Sensitization of human malignant lymphoid cells to etoposide by fucoidan, a brown seaweed polysaccharide. Experimental Oncology 2007 29 3 181 185 2-s2.0-36749088994 (Pubitemid 350206743)
    • (2007) Experimental Oncology , vol.29 , Issue.3 , pp. 181-185
    • Philchenkov, A.1    Zavelevich, M.2    Imbs, T.3    Zvyagintseva, T.4    Zaporozhets, T.5
  • 43
    • 0030890037 scopus 로고    scopus 로고
    • Vitamins and cancer
    • DOI 10.1016/S0304-3835(97)04662-4, PII S0304383597046624
    • van Poppel G., van den Berg H., Vitamins and cancer. Cancer Letters 1997 114 1-2 195 202 2-s2.0-0030890037 10.1016/S0304-3835(97)04662-4 (Pubitemid 27140112)
    • (1997) Cancer Letters , vol.114 , Issue.1-2 , pp. 195-202
    • Van Poppel, G.1    Van Den Berg, H.2
  • 46
    • 0025602410 scopus 로고
    • Inhibitory effects of fucoxanthin, a natural carotenoid, on N-myc expression and cell cycle progression in human malignant tumor cells
    • 2-s2.0-0025602410 10.1016/0304-3835(90)90068-9
    • Okuzumi J., Nishino H., Murakoshi M., Iwashima A., Tanaka Y., Yamane T., Fujita Y., Takahashi T., Inhibitory effects of fucoxanthin, a natural carotenoid, on N-myc expression and cell cycle progression in human malignant tumor cells. Cancer Letters 1990 55 1 75 81 2-s2.0-0025602410 10.1016/0304-3835(90)90068-9
    • (1990) Cancer Letters , vol.55 , Issue.1 , pp. 75-81
    • Okuzumi, J.1    Nishino, H.2    Murakoshi, M.3    Iwashima, A.4    Tanaka, Y.5    Yamane, T.6    Fujita, Y.7    Takahashi, T.8
  • 47
    • 0027480268 scopus 로고
    • Inhibitory effects of fucoxanthin, a natural carotenoid, on N-ethyl-N'-nitro-N-nitrosoguanidine-induced mouse duodenal carcinogenesis
    • Okuzumi J., Takahashi T., Yamane T., Kitao Y., Inagake M., Ohya K., Nishino H., Tanaka Y., Inhibitory effects of fucoxanthin, a natural carotenoid, on N-ethyl-N′-nitro-N-nitrosoguanidine-induced mouse duodenal carcinogenesis. Cancer Letters 1993 68 2-3 159 168 2-s2.0-0027480268 (Pubitemid 23090674)
    • (1993) Cancer Letters , vol.68 , Issue.2-3 , pp. 159-168
    • Okuzumi, J.1    Takahashi, T.2    Yamane, T.3    Kitao, Y.4    Inagake, M.5    Ohya, K.6    Nishino, H.7    Tanaka, Y.8
  • 52
    • 7744240624 scopus 로고    scopus 로고
    • Fucoxanthin induces apoptosis and enhances the antiproliferative effect of the PPARγ ligand, troglitazone, on colon cancer cells
    • DOI 10.1016/j.bbagen.2004.08.012, PII S0304416504002223
    • Hosokawa M., Kudo M., Maeda H., Kohno H., Tanaka T., Miyashita K., Fucoxanthin induces apoptosis and enhances the antiproliferative effect of the PPAR γ ligand, troglitazone, on colon cancer cells. Biochimica et Biophysica Acta 2004 1675 1 3 113 119 2-s2.0-7744240624 10.1016/j.bbagen.2004. 08.012 (Pubitemid 39463260)
    • (2004) Biochimica et Biophysica Acta - General Subjects , vol.1675 , Issue.1-3 , pp. 113-119
    • Hosokawa, M.1    Kudo, M.2    Maeda, H.3    Kohno, H.4    Tanaka, T.5    Miyashita, K.6
  • 53
    • 14644445985 scopus 로고    scopus 로고
    • Neoxanthin and fucoxanthin induce apoptosis in PC-3 human prostate cancer cells
    • DOI 10.1016/j.canlet.2004.07.048
    • Kotake-Nara E., Asai A., Nagao A., Neoxanthin and fucoxanthin induce apoptosis in PC-3 human prostate cancer cells. Cancer Letters 2005 220 1 75 84 2-s2.0-14644445985 10.1016/j.canlet.2004.07.048 (Pubitemid 40312020)
    • (2005) Cancer Letters , vol.220 , Issue.1 , pp. 75-84
    • Kotake-Nara, E.1    Asai, A.2    Nagao, A.3
  • 54
    • 18844385479 scopus 로고    scopus 로고
    • Antiproliferative effect of neoxanthin and fucoxanthin on cultured cells
    • DOI 10.1111/j.1444-2906.2005.00986.x
    • Kotake-Nara E., Sugawara T., Nagao A., Antiproliferative effect of neoxanthin and fucoxanthin on cultured cells. Fisheries Science 2005 71 2 459 461 2-s2.0-18844385479 10.1111/j.1444-2906.2005.00986.x (Pubitemid 40689911)
    • (2005) Fisheries Science , vol.71 , Issue.2 , pp. 459-461
    • Kotake-Nara, E.1    Sugawara, T.2    Nagao, A.3
  • 55
    • 34047207526 scopus 로고    scopus 로고
    • Fucoxanthin, a natural carotenoid, induces G1 arrest and GADD45 gene expression in human cancer cells
    • Yoshiko S., Hoyoko N., Fucoxanthin, a natural carotenoid, induces G1 arrest and GADD45 gene expression in human cancer cells. In Vivo 2007 21 2 305 309 2-s2.0-34047207526 (Pubitemid 46534285)
    • (2007) Vivo , vol.21 , Issue.2 , pp. 305-309
    • Yoshiko, S.1    Hoyoko, N.2
  • 56
    • 40949104695 scopus 로고    scopus 로고
    • Growth inhibition of human hepatic carcinoma HepG2 cells by fucoxanthin is associated with down-regulation of cyclin D
    • 2-s2.0-40949104695 10.1016/j.bbagen.2008.01.003
    • Das S. K., Hashimoto T., Kanazawa K., Growth inhibition of human hepatic carcinoma HepG2 cells by fucoxanthin is associated with down-regulation of cyclin D. Biochimica et Biophysica Acta 2008 1780 4 743 749 2-s2.0-40949104695 10.1016/j.bbagen.2008.01.003
    • (2008) Biochimica et Biophysica Acta , vol.1780 , Issue.4 , pp. 743-749
    • Das, S.K.1    Hashimoto, T.2    Kanazawa, K.3
  • 57
    • 0019781211 scopus 로고
    • Adult T-cell leukemia: Antigen in an ATL cell line and detection of antibodies to the antigen in human sera
    • Hinuma Y., Nagata K., Hanaoka M., Adult T-cell leukemia: antigen in an ATL cell line and detection of antibodies to the antigen in human sera. Proceedings of the National Academy of Sciences of the United States of America 1981 78 10 6476 6480 2-s2.0-0019781211 (Pubitemid 12179735)
    • (1981) Proceedings of the National Academy of Sciences of the United States of America , vol.78 , Issue.10 , pp. 6476-6480
    • Hinuma, Y.1    Nagata, K.2    Hanaoka, M.3
  • 58
    • 79952487250 scopus 로고    scopus 로고
    • Effects of fucoxanthin on proliferation and apoptosis in human gastric adenocarcinoma MGC-803 cells via JAK/STAT signal pathway
    • 2-s2.0-79952487250 10.1016/j.ejphar.2010.12.006
    • Yu R. X., Hu X. M., Xu S. Q., Jiang Z. J., Yang W., Effects of fucoxanthin on proliferation and apoptosis in human gastric adenocarcinoma MGC-803 cells via JAK/STAT signal pathway. European Journal of Pharmacology 2011 657 1 3 10 19 2-s2.0-79952487250 10.1016/j.ejphar.2010.12.006
    • (2011) European Journal of Pharmacology , vol.657 , Issue.13 , pp. 10-19
    • Yu, R.X.1    Hu, X.M.2    Xu, S.Q.3    Jiang, Z.J.4    Yang, W.5
  • 59
    • 33846550814 scopus 로고    scopus 로고
    • Antiangiogenic activity of brown algae fucoxanthin and its deacetylated product, fucoxanthinol
    • DOI 10.1021/jf062204q
    • Sugawara T., Matsubara K., Akagi R., Mori M., Hirata T., Antiangiogenic activity of brown algae fucoxanthin and its deacetylated product, fucoxanthinol. Journal of Agricultural and Food Chemistry 2006 54 26 9805 9810 2-s2.0-33846550814 10.1021/jf062204q (Pubitemid 46158974)
    • (2006) Journal of Agricultural and Food Chemistry , vol.54 , Issue.26 , pp. 9805-9810
    • Sugawara, T.1    Matsubara, K.2    Akagi, R.3    Mori, M.4    Hirata, T.5
  • 60
    • 0033198369 scopus 로고    scopus 로고
    • Effects of epoxycarotenoids, β-carotene, and retinoic acid on the differentiation and viability of the leukemia cell line NB4 in vitro
    • Duitsman P. K., Barua A. B., Becker B., Olson J. A., Effects of epoxycarotenoids, β -carotene, and retinoic acid on the differentiation and viability of the leukemia cell line NB4 in vitro. International Journal for Vitamin and Nutrition Research 1999 69 5 303 308 2-s2.0-0033198369 (Pubitemid 29460075)
    • (1999) International Journal for Vitamin and Nutrition Research , vol.69 , Issue.5 , pp. 303-308
    • Duitsman, P.K.1    Barua, A.B.2    Becker, B.3    Olson, J.A.4


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