Lentiviral vectors express chondroitinase ABC in cortical projections and promote sprouting of injured corticospinal axons

Journal of Neuroscience Methods

Volumn 201, Issue 1, 2011, Pages 228-238

  Zhao, Rong Rong ^a   Muir, Elizabeth M ^b   Alves, João Nuno ^a,b   Rickman, Hannah ^b   Allan, Anna Y ^b   Kwok, Jessica C ^a   Roet, Kasper C D ^c   Verhaagen, Joost ^c   Schneider, Bernard L ^d   Bensadoun, Jean Charles ^d,f   Ahmed, Sherif G ^e   Yáñez Muñoz, Rafael J ^e   Keynes, Roger J ^b   Fawcett, James W ^a   Rogers, John H ^b  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^c NETHERLANDS INSTITUTE FOR NEUROSCIENCE   (Netherlands)

^d EPFL   (Switzerland)

^e UNIVERSITY OF LONDON   (United Kingdom)

^f MERCK SERONO S A   (Switzerland)

Author keywords

Axon regeneration; Chondroitinase ABC; Corticospinal tract; Lentiviral vectors; Spinal cord injury

Indexed keywords

CHONDROITIN ABC LYASE; LENTIVIRUS VECTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; ENZYME THERAPY; GENE THERAPY; HUMAN; HUMAN CELL; MALE; NERVE FIBER; NERVE REGENERATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PYRAMIDAL TRACT; RAT; SPINAL CORD INJURY;

ANIMALS; CELLS, CULTURED; CEREBRAL CORTEX; CHONDROITIN ABC LYASE; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENETIC VECTORS; HEK293 CELLS; HUMANS; LENTIVIRUS; MALE; MICE; NERVE REGENERATION; PYRAMIDAL TRACTS; RATS; SHEEP; SPINAL CORD INJURIES;

EID: 80052339651     PISSN: 01650270     EISSN: 1872678X     Source Type: Journal    
DOI: 10.1016/j.jneumeth.2011.08.003     Document Type: Article

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