Enzymatic synthesis of dithiolopyrrolone antibiotics using cell-free extract of saccharothrix algeriensis NRRL B-24137 and biochemical characterization of two pyrrothine N-acyltransferases in this extract

Journal of Microbiology and Biotechnology

Volumn 24, Issue 1, 2014, Pages 26-35

  Saker, S ^a   Almaksour, Z Almousa ^a   Chorin, A C ^a   Lebrihi, A ^a   Mathieu, F ^a  

^a UNIVERSITÉ DE TOULOUSE   (France)

Author keywords

Acetyltransferase; Benzoyltransferase; Biochemical characterization; Dithiolopyrrolone biosynthesis; Saccharothrix algeriensis

Indexed keywords

ACETOACETYLPYRROTHINE; ACETYL COENZYME A; ACYLTRANSFERASE; ANTIBIOTIC AGENT; BENZOYLPYRROTHINE; BENZOYLTRANSFERASE; BUTYRYLPYRROTHINE; CROTONOYLPYRROTHINE; CYCLIC ACYL GROUP; DITHIOLOPYRROLONE ANTIBIOTIC AGENT; HEXANOYLPYRROTHINE; HOLOMYCIN; HYDROXYBUTYRYLPYRROTHINE; LINEAR ACYL GROUP; POLYFUNCTIONAL GROUP; PYRROTHINE N ACYLTRANSFERASE; THIOLUTIN; UNCLASSIFIED DRUG;

ARTICLE; BACTERIUM; CELL FREE SYSTEM; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME KINETICS; ENZYME STABILITY; ENZYME SUBSTRATE; ENZYME SYNTHESIS; FERMENTATION; IN VITRO STUDY; NONHUMAN; PH; PROCESS OPTIMIZATION; SACCHAROTHRIX ALGERIENSIS; STRUCTURE ACTIVITY RELATION; TEMPERATURE DEPENDENCE; THERMOSTABILITY;

ACTINOMYCETALES; ACYLTRANSFERASES; ANTI-BACTERIAL AGENTS; ENZYME STABILITY; FERMENTATION; HYDROGEN-ION CONCENTRATION; KINETICS; TEMPERATURE;

EID: 84893145044     PISSN: 10177825     EISSN: 17388872     Source Type: Journal    
DOI: 10.4014/jmb.1309.09035     Document Type: Article

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