Identification and heterologous expression of the biosynthetic gene cluster for holomycin produced by Streptomyces clavuligerus

Process Biochemistry

Volumn 46, Issue 3, 2011, Pages 811-816

  Huang, Sheng ^a   Zhao, Yudong ^a   Qin, Zhiwei ^c   Wang, Xiaoling ^c   Onega, Mayca ^c   Chen, Li ^a   He, Jing ^a   Yu, Yi ^a,b   Deng, Hai ^c  

^a HUAZHONG AGRICULTURAL UNIVERSITY   (China)

^b WUHAN UNIVERSITY   (China)

^c UNIVERSITY OF ABERDEEN   (United Kingdom)

Author keywords

Biosynthesis; Dithiolopyrrolone; Heterologous expression; Holomycin; NRPS

Indexed keywords

ADENYLATION; BIOINFORMATICS ANALYSIS; BIOSYNTHETIC GENE; BIOSYNTHETIC GENE CLUSTER; DISULFIDE BONDS; DITHIOLOPYRROLONE; GENE CLUSTERS; HETEROCYCLIZATIONS; HETEROLOGOUS EXPRESSION; HOLOMYCIN; KNOCK OUTS; MULTI DOMAINS; NATURAL PRODUCTS; NONRIBOSOMAL PEPTIDE SYNTHETASES; NRPS; OXIDATIVE REACTION; STREPTOMYCES CLAVULIGERUS; THIOESTERASES; THIOLATION;

BIOCHEMISTRY; BIOINFORMATICS; BIOSYNTHESIS;

GENE EXPRESSION;

STREPTOMYCES CLAVULIGERUS;

EID: 79951509309     PISSN: 13595113     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.procbio.2010.11.024     Document Type: Article

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