Cloning and characterization of the biosynthetic gene cluster of the bacterial RNA polymerase inhibitor tirandamycin from marine-derived Streptomyces sp. SCSIO1666

Biochemical and Biophysical Research Communications

Volumn 406, Issue 3, 2011, Pages 341-347

  Mo, Xuhua ^a,b   Wang, Zhongwen ^a   Wang, Bo ^a   Ma, Junying ^a   Huang, Hongbo ^a   Tian, Xinpeng ^a   Zhang, Si ^a   Zhang, Changsheng ^a   Ju, Jianhua ^a  

^a SOUTH CHINA SEA INSTITUTE OF OCEANOLOGY   (China)

^b UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

Author keywords

Biosynthesis; Cytochrome P450 monooxygenase; Negative regulator; Positive regulator; Streptomyces sp. SCSIO1666; Tirandamycin

Indexed keywords

APRAMYCIN; CYTOCHROME P450; FAD DEPENDENT OXIDOREDUCTASE; OXIDOREDUCTASE; PHOSPHOPANTETHEINYL TRANSFERASE; POLYKETIDE SYNTHASE; PROTEIN; RNA DIRECTED RNA POLYMERASE INHIBITOR; THIOL ESTER HYDROLASE; TIRANDAMYCIN; TRANSCRIPTION FACTOR LUXR; TRANSCRIPTION FACTOR TETR; TRANSFERASE; TRDK PROTEIN; TYPE 2 THIOESTERASE; UNCLASSIFIED DRUG;

ADENYLATION; ARTICLE; BIOINFORMATICS; BIOSYNTHESIS; DNA FLANKING REGION; GENE CASSETTE; GENE CLUSTER; GENE INACTIVATION; GENE SEQUENCE; MOLECULAR CLONING; NONHUMAN; NONRIBOSOMAL PEPTIDE SYNTHESIS; NUCLEOTIDE SEQUENCE; OPEN READING FRAME; PRIORITY JOURNAL; STREPTOMYCES; TRANSCRIPTION REGULATION;

AMINOGLYCOSIDES; CLONING, MOLECULAR; DNA-DIRECTED RNA POLYMERASES; GENES, BACTERIAL; MULTIGENE FAMILY; STREPTOMYCES;

BACTERIA (MICROORGANISMS); STREPTOMYCES SP.;

EID: 79952735817     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2011.02.040     Document Type: Article

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